Publications from CoRe members are listed below to illustrate the breadth and depth of our research activities. The current selection reflects research published by our members from January 2024 to November 2026.

To view a CoRe member’s recent publication history, click their name to open the dropdown. For further information about a member’s publication history, please visit the webpage linked on their Member Profile.

Featured Publication

Nikitin Lab

Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39366996; PMCID: PMC11452611.

Dr. Alexander Nikitin‘s (Professor of Pathology, Department of Biomedical Sciences) laboratory published an article in Nature Communications earlier this month, co-first authored by Dr. Andrea Flesken-Nikitin (Assistant Research Professor) and graduate student Coulter Ralston. The article, titled “Pre-ciliated tubal epithelial cells are prone to initiating of high-grade serous ovarian carcinoma,” highlights transitional cells in the fallopian tube, known as a pre-ciliated tubal epithelial cells, as being particularly susceptible to cancer. High-grade serous carcinoma (HGSC) can develop in both the ovary and a section of the fallopian tube, and this publication reflects the lab’s first time identifying susceptible cells in the fallopian tube.

VISIT PUBLICATION

Antczak

2024

Radovic L, Remer V, Rigler D, Bozlak E, Allen L, Brem G, Reissman M, Brockmann GA, Ropka-Molik K, Stefaniuk-Szmukier M, Kalinkova L, Kalashnikov VV, Zaitev AM, Raudsepp T, Castaneda C, von Butler-Wemken I, Patterson Rosa L, Brooks SA, Novoa-Bravo M, Kostaras N, Abdurasulov A, Antczak DF, Miller DC, Lopes MS, da Câmara Machado A, Lindgren G, Juras R, Cothran G, Wallner B. The global spread of Oriental Horses in the past 1,500 years through the lens of the Y chromosome. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2414408121. doi: 10.1073/pnas.2414408121. Epub 2024 Nov 18. PubMed PMID: 39556761; PubMed Central PMCID: PMC11626155.

Aravin

2026

Chen P, Xu P, Waseem H, McCormick J, Pan KC, Aravin AA, Clark AG, Feschotte C. piRNA loss unleashes episodic transposition bursts. Proc Natl Acad Sci U S A. 2026 Nov 3;123(44):e2623866123. doi: 10.1073/pnas.2623866123. Epub 2026 Oct 28. PMID: 42949961.
Luo Y, Zhou W, Jin Z, Godneeva B, Huang X, Wang H, He P, Huang Y, Aravin AA. piRNA direct the chromatin reader to its genomic targets. bioRxiv [Preprint]. 2026 May 9:2026.05.08.723782. doi: 10.64898/2026.05.08.723782. PMID: 42146450; PMCID: PMC13174600.
Luo Y, de Oliveira DS, He P, Aravin AA. A trans-piRNA network and transcriptional antagonism shape piRNA cluster function. bioRxiv [Preprint]. 2026 Apr 9:2026.04.08.717276. doi: 10.64898/2026.04.08.717276. PMID: 41993540; PMCID: PMC13082016.

2025

Chen P, Pan KC, Park EH, Luo Y, Lee YCG, Aravin AA. Escalation of genome defense capacity enables control of an expanding meiotic driver. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2418541122. doi: 10.1073/pnas.2418541122. Epub 2025 Jan 7. PMID: 39772737; PMCID: PMC11745323.

Bailey

2025

Bailey, C.S., Beachler, T.M., Mochel, J.P., Wulf, L.W., Yaeger, M., Kundu, D., Withowski, K. and Papich, M.G. (2025), Penicillin and Gentamicin Concentrations in the Uterine Fluid of Non-Pregnant Mares Following a Single Intrauterine Infusion. J Vet Pharmacol Therap, 48: 389-396. https://doi.org/10.1111/jvp.13518

Clark

2026

Chen P, Xu P, Waseem H, McCormick J, Pan KC, Aravin AA, Clark AG, Feschotte C. piRNA loss unleashes episodic transposition bursts. Proc Natl Acad Sci U S A. 2026 Nov 3;123(44):e2623866123. doi: 10.1073/pnas.2623866123. Epub 2026 Oct 28. PMID: 42949961.
Potdar S, Makhmudova T, Schenck-Davis A, Delbare SYN, Jain AM, Hafezi Y, Clark AG, Wolfner MF. No detectable effect of P2 neurons on female post-mating changes in sleep and feeding in Drosophila melanogaster. bioRxiv [Preprint]. 2026 Sep 16:2026.09.10.750755. doi: 10.64898/2026.09.10.750755. PMID: 42780211; PMCID: PMC13596533.
Chen Y, Shah SR, Leung AK, Paramo MI, Gonzales C, Cochran K, Wang A, Kundaje A, Clark AG, Lis JT, Yu H. Directionality of transcriptional regulatory elements. Nat Commun. 2026 Sep 10;17(1):10671. doi: 10.1038/s41467-026-76415-5. PMID: 42860398; PMCID: PMC13655173.
McCormick BK, Barbash DA, Clark AG. The Stellate meiotic drive system of Drosophila melanogaster is active in contemporary populations. Genetics. 2026 Aug 5;233(4):iyag153. doi: 10.1093/genetics/iyag153. PMID: 42302288; PMCID: PMC13439701.
Nguyen TN, Cosgrove EJ, Chen N, Lehr N, Lokey MG, Beaudry FEG, Fitzpatrick SW, Bowman R, Miller KE, Fitzpatrick JW, Clark AG. Florida scrub-jay genomes across space and time reveal impacts of population decline and reduced gene flow. Curr Biol. 2026 Aug 3;36(15):3794-3807.e4. doi: 10.1016/j.cub.2026.06.044. Epub 2026 Jul 13. PMID: 42442356.
Li W, Chen J, Liu C, Wang Q, Wang Y, Clark AG, Lu J. Comparative population genomics reveals adaptive convergence in two Drosophila species across global environments. Cell Rep. 2026 Jul 28;45(7):117642. doi: 10.1016/j.celrep.2026.117642. Epub 2026 Jul 3. PMID: 42397734.
Afkhami M, Li ML, Liang C, Patel PH, Buehner NA, Wolfner MF, Clark AG. Application of the Bradley-Terry model to quantify components of sperm competition. bioRxiv [Preprint]. 2026 Jul 10:2026.07.06.736847. doi: 10.64898/2026.07.06.736847. PMID: 42465271; PMCID: PMC13370413.
Carlisle JA, Craig RMJ, Matera-Vatnick M, Villanueva BM, Andrus AR, Cosgrove EJ, Chen DS, Clark AG, Wolfner MF. Female genetic variation controlling timing of mating plug ejection in Drosophila melanogaster. bioRxiv [Preprint]. 2026 Jul 1:2026.06.27.734984. doi: 10.64898/2026.06.27.734984. PMID: 42427634; PMCID: PMC13344986.
Carlisle JA, McCormick BK, Verbakel L, von Philipsborn AC, Wolfner MF, Clark AG. Correlated gene copy number changes in a seminal fluid protein network in Drosophila. Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2529899123. doi: 10.1073/pnas.2529899123. Epub 2026 Jun 16. PMID: 42301780; PMCID: PMC13291673.
Barad A, Xu H, Clark AG, Gu Z, Pressman EK, Ye K, O’Brien KO. A genetic association study of iron absorption in adults of East Asian or Northern European ancestry from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr. 2026 Jun;123(6):101298. doi: 10.1016/j.ajcnut.2026.101298. Epub 2026 Mar 25. PMID: 41895699; PMCID: PMC13173465.
Shah SR, Chen Y, Leung AK, Navarro PVC, Paramo MI, Gupta J, Gurumurthy A, Fite RF, Weimer AK, Cochran K, Wang A, Du Q, Mohyeldin AM, Egli D, Kundaje A, Creusot RJ, Ryan RJH, Snyder MP, Clark AG, Lis JT, Yu H. The nascent transcriptome delineates the regulatory landscape in human health and disease. bioRxiv [Preprint]. 2026 Jun 9:2025.09.24.676871. doi: 10.1101/2025.09.24.676871. PMID: 41040139; PMCID: PMC12485982.
Xu P, Liang S, Hahn A, Zhao V, Lo WT’, Haller BC, Sobkowiak B, Chitwood MH, Colijn C, Cohen T, Rhee KY, Messer PW, Wells MT, Clark AG, Kim J. e3SIM: Epidemiological-ecological-evolutionary simulation framework for genomic epidemiology. Methods Ecol Evol. 2026 Apr;17(4):1051-1059. doi: 10.1111/2041-210x.70278. Epub 2026 Mar 5. PMID: 41953710; PMCID: PMC13055929.

2025

Carlisle JA, McCormick BK, Verbakel L, von Philipsborn AC, Wolfner MF, Clark AG. Correlated Gene Copy Number Changes in a Seminal Fluid Protein Network in Drosophila. bioRxiv [Preprint]. 2025 Nov 3:2025.10.27.684572. doi: 10.1101/2025.10.27.684572. Update in: Proc Natl Acad Sci U S A. 2026 Jun 23;123(25):e2529899123. doi: 10.1073/pnas.2529899123. PMID: 41279800; PMCID: PMC12636338.
Chen J, Liu C, Li W, Clark AG, Wang Z, Lu J. Pervasive sex-dependent effects in the genetic architecture of starvation resistance in Drosophila melanogaster. Sci Adv. 2025 Sep 26;11(39):eadt3560. doi: 10.1126/sciadv.adt3560. Epub 2025 Sep 26. PMID: 41004585; PMCID: PMC12466915.
Shah SR, Chen Y, Leung AK, Navarro PVC, Paramo MI, Gupta J, Gurumurthy A, Fite RF, Weimer AK, Du Q, Mohyeldin AM, Egli D, Creusot RJ, Ryan RJH, Snyder MP, Clark AG, Lis JT, Yu H. The regulatory landscape of nascent transcription in human health and disease. bioRxiv [Preprint]. 2025 Sep 26:2025.09.24.676871. doi: 10.1101/2025.09.24.676871. PMID: 41040139; PMCID: PMC12485982.
Chen DS, Marrero K, Sanchez-Lopez JA, Belenky M, Thomalla JM, Buehner NA, Apel I, Levi Y, Hafezi Y, Wang S, Clark AG, Heifetz Y, Siegal ML, Wolfner MF. Asymmetric development and function of paired sperm-storage organs in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2025 Aug 26;122(34):e2512096122. doi: 10.1073/pnas.2512096122. Epub 2025 Aug 19. PMID: 40828028; PMCID: PMC12403100.
Forsberg SKG, Melo D, Wolf SW, Grenier JK, Tang M, Henry LP, Pallares LF, Clark AG, Ayroles JF. Longitudinal sequencing reveals polygenic and epistatic nature of genomic response to selection. Proc Natl Acad Sci U S A. 2025 Jun 24;122(25):e2410452122. doi: 10.1073/pnas.2410452122. Epub 2025 Jun 18. PMID: 40531879; PMCID: PMC12207516.
Cappello L, Lo WT’, Zhang JZ, Xu P, Barrow D, Chopra I, Clark AG, Wells MT, Kim J. Bayesian phylodynamic inference of population dynamics with dormancy. Proc Natl Acad Sci U S A. 2025 May 6;122(18):e2501394122. doi: 10.1073/pnas.2501394122. Epub 2025 May 2. PMID: 40314983; PMCID: PMC12067208.
Dong C, Xia S, Zhang L, Arsala D, Fang C, Tan S, Clark AG, Long M. Subcellular Enrichment Patterns of New Genes in Drosophila Evolution. Mol Biol Evol. 2025 Feb 3;42(2):msaf038. doi: 10.1093/molbev/msaf038. PMID: 39920336; PMCID: PMC11843443.

2024

Xue H, Delbare SYN, Wells MT, Basu S, Clark AG. Integrative Analysis of Differentially Expressed Genes in Time-Course Multi-Omics Data with MINT-DE. Res Sq [Preprint]. 2024 Dec 23:rs.3.rs-3806701. doi: 10.21203/rs.3.rs-3806701/v2. PMID: 38260696; PMCID: PMC10802680.
Said I, Barbash DA, Clark AG. The Structure of Simple Satellite Variation in the Human Genome and Its Correlation With Centromere Ancestry. Genome Biol Evol. 2024 Aug 5;16(8):evae153. doi: 10.1093/gbe/evae153. PMID: 39018452; PMCID: PMC11305138.
Srivastav SP, Feschotte C, Clark AG. Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary. Genome Res. 2024 Jun 25;34(5):711-724. doi: 10.1101/gr.278062.123. PMID: 38749655; PMCID: PMC11216404.
Barad A, Clark AG, Pressman EK, O’Brien KO. Associations Between Genetically Predicted Iron Status and Cardiovascular Disease Risk: A Mendelian Randomization Study. J Am Heart Assoc. 2024 Jun 4;13(11):e034991. doi: 10.1161/JAHA.124.034991. Epub 2024 May 31. PMID: 38818967; PMCID: PMC11255641.
Hafezi Y, Omurzakov A, Carlisle JA, Caldas IV, Wolfner MF, Clark AG. The Drosophila melanogaster Y-linked gene, WDY, is required for sperm to swim in the female reproductive tract. Commun Biol. 2024 Jan 12;7(1):90. doi: 10.1038/s42003-023-05717-x. PMID: 38216628; PMCID: PMC10786823.
Flynn JM, Ahmed-Braimah YH, Long M, Wing RA, Clark AG. High-Quality Genome Assemblies Reveal Evolutionary Dynamics of Repetitive DNA and Structural Rearrangements in the Drosophila virilis Subgroup. Genome Biol Evol. 2024 Jan 5;16(1):evad238. doi: 10.1093/gbe/evad238. PMID: 38159044; PMCID: PMC10783647.

Cohen, Paula

2026

de Almeida LP, Butler VM, Marin L, Nowak KP, Ostoja-Helczynski M, Ragsdale C, Kawecka MK, Carr KD, Cohen PE, Dresser ME, Burgess SM, Finn EH, Pezza RJ. Stepwise pairing and fast transition regulated by recombination drive meiotic chromosome interactions. Nat Commun. 2026 Sep 24;17(1):11072. doi: 10.1038/s41467-026-78036-4. PMID: 42918807; PMCID: PMC13691100.
Carro MLM, Dziubek A, Touey-May A, Popkowski EA, Abdelmassih M, Simon LE, Tanis SL, Ahmed F, Grenier JK, Grimson A, Cohen PE. Argonaute proteins orchestrate Meiotic Sex Chromosome Inactivation and timing of the spermatogenic transcriptional program. PLoS Genet. 2026 Jun 29;22(6):e1012217. doi: 10.1371/journal.pgen.1012217. PMID: 42371982; PMCID: PMC13336459.
Carr KD, O’Donnell E, Horan TS, Adjei-Boadu MS, Wood AJ, Zhang Y, Edelmann W, de Las Mercedes Carro M, Cohen PE. A mammalian-specific domain of MSH5 drives the transition from crossover licensing to designation during meiotic prophase I. bioRxiv [Preprint]. 2026 Jun 18:2026.06.16.731784. doi: 10.64898/2026.06.16.731784. PMID: 42367974; PMCID: PMC13307971.
Horan TS, Wood A, Tanis S, Peirau-Gabarrell C, Cohen PE. Molecular assessment of recombination processing across genetically diverse mouse strains reveals sexually dimorphic determinants of crossover distribution beyond chromosome length. Mol Biol Evol. 2026 Jun 4;43(6):msag130. doi: 10.1093/molbev/msag130. PMID: 42226637; PMCID: PMC13267643.
Tanis S, Simon LE, Alexander AK, Horan TS, Carro MLM, Bonnett SJ, Xie A, Ben-Shlomo R, Owens CE, Danko CG, Lujic J, Cohen PE. Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2517498123. doi: 10.1073/pnas.2517498123. Epub 2026 Apr 7. PMID: 41945432; PMCID: PMC13080027.

2025

Horan TS, Wood A, Tanis S, Gabarrell CP, Cohen PE. Chromosome length is not the sole determinant of sexually dimorphic crossover rates during mammalian meiosis: Insights from genetically diverse mouse strains. bioRxiv [Preprint]. 2025 Dec 22:2025.12.19.695521. doi: 10.64898/2025.12.19.695521. PMID: 41509471; PMCID: PMC12776159.
Wood AJ, Ahmed RM, Simon LE, Bradley RA, Gray S, Wolff ID, Cohen PE. CNTD1 is crucial for crossover formation in female meiosis and for establishing the ovarian reserve. J Cell Biol. 2025 Aug 4;224(8):e202401021. doi: 10.1083/jcb.202401021. Epub 2025 Jun 9. PMID: 40488668; PMCID: PMC12147665.
Carro MLM, Dziubek A, Touey A, Popkowski EA, Abdelmassih M, Simon L, Tanis S, Ahmed F, Grenier JK, Grimson A, Cohen PE. Argonaute proteins regulate the timing of the spermatogenic transcriptional program. bioRxiv [Preprint]. 2025 Jan 1:2024.12.31.630913. doi: 10.1101/2024.12.31.630913. PMID: 39803480; PMCID: PMC11722363.

2024

Condezo YB, Sainz-Urruela R, Gomez-H L, Salas-Lloret D, Felipe-Medina N, Bradley R, Wolff ID, Tanis S, Barbero JL, Sánchez-Martín M, de Rooij D, Hendriks IA, Nielsen ML, Gonzalez-Prieto R, Cohen PE, Pendas AM, Llano E. RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2320995121. doi: 10.1073/pnas.2320995121. Epub 2024 Jun 12. Erratum in: Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2418611121. doi: 10.1073/pnas.2418611121. PMID: 38865271; PMCID: PMC11194559.
Horan TS, Ascenção CFR, Mellor C, Wang M, Smolka MB, Cohen PE. The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice. PLoS Genet. 2024 Feb 20;20(2):e1011175. doi: 10.1371/journal.pgen.1011175. PMID: 38377115; PMCID: PMC10906868.

Cohen, Roy

2026

Huynh A, Byron MJ, Lenfest MI, Mukhtarov F, Yasmin R, Cohen R, Rishniw M, Travis AJ, Merbl Y. Neuron-specific enolase enzymatic activity as a biomarker to discriminate neurologic and orthopedic gait abnormalities in dogs. J Vet Intern Med. 2026 May 4;40(3):aalag122. doi: 10.1093/jvimsj/aalag122. PMID: 42341219; PMCID: PMC13293243.

2025

White MA, Cohen R, Travis AJ. Real-Time Imaging of Calcium Dynamics in Human Sperm After Precise Single-Cell Stimulation. Methods Mol Biol. 2025;2861:247-256. doi: 10.1007/978-1-0716-4164-4_18. PMID: 39395110.

Comizzoli

2026

Comizzoli P, Lee PC. Recent advances in long-term preservation of viable gonadal tissues from Carnivora. Theriogenology. 2026 Oct 26;268:118288. doi: 10.1016/j.theriogenology.2026.118288. Epub ahead of print. PMID: 42933343.
Palmer GA, Gambini A, Pask A, Comizzoli P. One Embryology: impactful connections between human- and wildlife-assisted reproduction. J Assist Reprod Genet. 2026 Oct 9. doi: 10.1007/s10815-026-04044-4. Epub ahead of print. PMID: 42853361.
Comizzoli P. A 30-year journey in wildlife assisted reproductive technologies. Anim Reprod. 2026 Sep 21;23(4):e20260101. doi: 10.1590/1984-3143-AR2026-0101. PMID: 42877386; PMCID: PMC13667901.
Hagedorn M, Comizzoli P, Parenti LR, Craddock RA, Mabee P, Meinke B, Bischof JC, Sandlin RD, Tessier SN, Toner M, Ambrose R, Journaux B, Fitzpatrick G. Inducing radiation resilience in frozen animal cells via mRNA coding for tardigrade damage-suppressor protein in support of space travel and Lunar storage. J Hered. 2026 Sep 3;117(5):1087-1092. doi: 10.1093/jhered/esag030. PMID: 42096497; PMCID: PMC13539440.
DeCandia AL, Tennenbaum SR, Santymire R, Livieri T, Bortner R, Garelle D, Crosier A, Marinari P, Pukazhenthi BS, Comizzoli P, Maldonado JE, Koepfli KP, vonHoldt BM. Ex situ reared black-footed ferrets exhibit altered sperm DNA methylation. J Hered. 2026 Sep 3;117(5):1093-1106. doi: 10.1093/jhered/esaf056. PMID: 40847813.
Ruggeri E, Gambini A, Galli C, Mastromonaco G, Comizzoli P. Unlocking the value of cloning for wildlife conservation with research priorities, open collaborations, data/information sharing, and ethics as keys to success. Reprod Fertil Dev. 2026 Aug 18;38(12):RD26167. doi: 10.1071/RD26167. PMID: 42581573.
Sandoval EDP, Lee PC, Duarte JMB, Comizzoli P. Slow Freezing vs. Vitrification of Testicular Tissue in Nontraditional Animal Models. Biopreserv Biobank. 2026 Aug;24(4):346-356. doi: 10.1177/19475535251391026. Epub 2025 Oct 28. PMID: 41151088.
Sosnicki DM, Jensen A, Spicer O, Comizzoli P. Response of Domestic Cat Primary Fibroblasts to Trehalose-Loading Methods, Air-Drying, and Storage Conditions at Non-freezing Temperatures. Biopreserv Biobank. 2026 Jul 4:19475535261463415. doi: 10.1177/19475535261463415. Epub ahead of print. PMID: 42400274.
Amorim CA, Chuva de Sousa Lopes SM, Klutstein M, Brieño-Enriquez MA, Anderson RA, Duncan FE, De Vos M, Damdimopoulou P, Comizzoli P, Williams SA, O’Meara Y, Khattak H, Segers S, Gruhn JR, Roig I, Kristensen SG. Proceedings of the first European Ovary Workshop (EOW 2025), Lagos, Portugal, 17-20 February 2025. Mol Hum Reprod. 2026 Jul 7;32(3):gaag039. doi: 10.1093/molehr/gaag039. PMID: 42363403.
Bezerra LGP, Silva AM, Dantas MRT, Santos RPD, Moreira SSJ, Pereira AG, de Oliveira MF, Jorge-Neto PN, Comizzoli P, Silva AR. Individual Variation in Sperm Quality and Resilience to Cryopreservation with Different Dimethyl Sulfoxide Concentrations in Captive Greater Rheas (Rhea americana). Biopreserv Biobank. 2026 Jun 23:19475535261451610. doi: 10.1177/19475535261451610. Epub ahead of print. PMID: 42334403.
Yang Y, Thongthip N, Angkawanish T, Comizzoli P, Chatdarong K. Influence of intrinsic and extrinsic factors on quality of Asian elephant semen – Current knowledge and new research directions. Anim Reprod Sci. 2026 May;288:108122. doi: 10.1016/j.anireprosci.2026.108122. Epub 2026 Feb 3. PMID: 41679093.
Lee PC, Yang Y, Chatdarong K, Comizzoli P. Dehydration-based preservation of cat cumulus-oocyte complexes is not improved by membrane-permeable trehalose. Front Vet Sci. 2026 Apr 7;13:1805930. doi: 10.3389/fvets.2026.1805930. PMID: 42022390; PMCID: PMC13095549.
Holt WV, Comizzoli P. Reproductive science and wildlife conservation: the knowns and unknowns! Reprod Fertil. 2026 Mar 13;7(1):RAF250135. doi: 10.1530/RAF-25-0135. PMID: 41746758; PMCID: PMC13010306.
Pollard CL, Hashem NM, Sontakke SD, Comizzoli P. Editorial: Advancing animal reproduction: Artificial Intelligence, precision technologies and reproductive biotechnologies. Front Vet Sci. 2026 Feb 10;13:1790388. doi: 10.3389/fvets.2026.1790388. PMID: 41743560; PMCID: PMC12930625.
Amelkina O, Comizzoli P. Making sense of expanding transcriptomic data: network-based approaches for studying reproduction in domestic and wild animal species. Front Vet Sci. 2026 Jan 12;12:1728981. doi: 10.3389/fvets.2025.1728981. PMID: 41602618; PMCID: PMC12832437.
Mastromonaco G, Mackie P, Russell V, Comizzoli P. Stem Cells and Wildlife Conservation. Adv Exp Med Biol. 2026;16:313-339. doi: 10.1007/978-3-031-87707-0_10. PMID: 41718875.
Lee PC, Comizzoli P. Biobanking biodiversity: recent strategies, challenges, and opportunities. J Reprod Dev. 2026;72(3):210-224. doi: 10.1262/jrd.2025-114. PMID: 42309731; PMCID: PMC13286723.
Holt WV, Comizzoli P. Reproductive Strategies and Their Relevance to Vertebrate Conservation. Adv Exp Med Biol. 2026;16:17-39. doi: 10.1007/978-3-031-87707-0_2. PMID: 41718867.
Comizzoli P, Brown J, Holt WV. Reproductive Sciences to the Rescue of Wild Animal Species. Adv Exp Med Biol. 2026;16:1-16. doi: 10.1007/978-3-031-87707-0_1. PMID: 41718866.
Holt WV, Brown J, Comizzoli P. How to Ensure a Bright Future for Reproductive Sciences in Animal Conservation. Adv Exp Med Biol. 2026;16:647-656. doi: 10.1007/978-3-031-87707-0_19. PMID: 41718884.
Silva AR, Bezerra LGP, Dos Santos RP, Comizzoli P. The role of emerging assisted reproductive technologies in the conservation of neotropical wild mammals – challenges, advances and perspectives. J Reprod Dev. 2026;72(3):196-209. doi: 10.1262/jrd.2025-111. PMID: 42309730; PMCID: PMC13286722.
Lee PC, Comizzoli P. Microwave-Assisted Dehydration, Non-Cryogenic Storage, and Rehydration of Spermatozoa and Germinal Vesicles. Methods Mol Biol. 2026;3038:135-145. doi: 10.1007/978-1-0716-5292-3_9. PMID: 42681382.

2025

Amelkina O, Lee PC, Sosnicki DM, Martinez P, Nussbaum J, Willis H, Comizzoli P. Effects of microwave-assisted dehydration on the structure and function of ovarian cortex in the domestic cat model: new insights for future storage of living tissues at ambient temperatures†. Biol Reprod. 2025 Dec 16;113(6):1601-1615. doi: 10.1093/biolre/ioaf203. PMID: 40891504.
Sandoval EDP, Lee PC, Duarte JMB, Comizzoli P. Slow Freezing vs. Vitrification of Testicular Tissue in Nontraditional Animal Models. Biopreserv Biobank. 2025 Oct 28. doi: 10.1177/19475535251391026. Epub ahead of print. PMID: 41151088.
Cavalcante YCS, Santos CS, Dantas LL, Santos RP, Matos YG, Pereira AG, Beraldo KRF, Juliano MA, Brandão FZ, Feijó FMC, Franco de Oliveira M, Mota RA, Comizzoli P, Silva AR. Relationship between the composition of vaginal bacterial populations and the reproductive stage in captive collared peccaries. Reprod Fertil. 2025 Oct 14;6(4):e250072. doi: 10.1530/RAF-25-0072. PMID: 41026639; PMCID: PMC12524037.
da Silva Cavalcante YC, Comizzoli P, Silva AR. How deciphering the reproductive microbiomes can contribute to the conservation of wild mammalian species – A review. Anim Reprod Sci. 2025 Oct;281:107981. doi: 10.1016/j.anireprosci.2025.107981. Epub 2025 Aug 26. PMID: 40886421.
Amelkina O, Lee PC, Sosnicki DM, Martinez P, Nussbaum J, Willis H, Comizzoli P. Effects of microwave-assisted dehydration on the structure and function of ovarian cortex in the domestic cat model – New insights for future storage of living tissues at ambient temperatures†. Biol Reprod. 2025 Sep 2:ioaf203. doi: 10.1093/biolre/ioaf203. Epub ahead of print. PMID: 40891504.
DeCandia AL, Tennenbaum SR, Santymire R, Livieri T, Bortner R, Garelle D, Crosier A, Marinari P, Pukazhenthi BS, Comizzoli P, Maldonado JE, Koepfli KP, vonHoldt BM. Ex situ reared black-footed ferrets exhibit altered sperm DNA methylation. J Hered. 2025 Aug 23:esaf056. doi: 10.1093/jhered/esaf056. Epub ahead of print. PMID: 40847813.
Hagedorn M, Zuchowicz N, Henley EM, Lager C, Perry R, Blackburn H, Bouwmeester J, Brunel O, Carter C, Rodriguez-Clark KM, Comizzoli P, Firchau B, Miller D, Moore J, Muller EM, O’Neil K, Quattrini AM, Zoccola D, Banaszak AT, Marhaver KL, Hobbs R, O’Brien JK, Daly J. Conservation of coral genetic diversity through a global biorepository network. Bioscience. 2025 Aug 21;75(11):966-974. doi: 10.1093/biosci/biaf117. Erratum in: Bioscience. 2026 Mar 18;76(7):661. doi: 10.1093/biosci/biag031. PMID: 41312294; PMCID: PMC12650515.
Pereira AG, da Silva AM, Pereira Bezerra LG, Cottin de Albuquerque JL, Costa Bezerra GS, Pereira AF, Bezerra de Moura CE, Comizzoli P, Silva AR. Use of organotypic or three-dimensional systems with basic fibroblast growth factor for in vitro culture of immature collared peccary testicle. Reprod Fertil. 2025 Aug 8;6(3):e250026. doi: 10.1530/RAF-25-0026. PMID: 40737041; PMCID: PMC12344399.
Yang Y, Kittisirikul N, Langkaphin W, Angkawanish T, Comizzoli P, Chatdarong K. Differentiating the estrous cycle phases using vaginal vestibule pH and cytology in Asian elephants (Elephas maximus) in human care. Vet J. 2025 Jun;311:106324. doi: 10.1016/j.tvjl.2025.106324. Epub 2025 Mar 8. PMID: 40064394.
Silva AM, Pereira AG, Bezerra GSC, Matos YG, Bezerra LGP, Pereira AF, Oliveira MF, Comizzoli P, Silva AR. Solid Surface Vitrification Is Better than Slow Freezing for the Long-Term Preservation of Testicular Fragments from Prepubertal Collared Peccaries (Pecari tajacu Linnaeus, 1758). Animals (Basel). 2025 May 20;15(10):1488. doi: 10.3390/ani15101488. PMID: 40427365; PMCID: PMC12108413.
Comizzoli P, Paulson RJ. Bridging studies in wild animal species and humans to better understand, assist, and control reproduction. F S Rep. 2025 Apr 15;6(Suppl 1):1-2. doi: 10.1016/j.xfre.2025.01.013. PMID: 40487322; PMCID: PMC12139229.
Fujihara M, Comizzoli P. Human and wildlife biobanks of germplasms and reproductive tissues can contribute to a broader concept of One Health. F S Rep. 2025 Apr 15;6(Suppl 1):63-66. doi: 10.1016/j.xfre.2025.01.004. PMID: 40487327; PMCID: PMC12139243.
Silva AM, Lima GL, Comizzoli P, Silva AR. Gonadal tissue preservation technologies and culture offer opportunities to bridge knowledge between wildlife and humans. F S Rep. 2025 Apr 15;6(Suppl 1):50-54. doi: 10.1016/j.xfre.2025.01.009. PMID: 40487320; PMCID: PMC12139249.
Bovell RTM, Comizzoli P, Nagashima JB, Santiestevan J, Crosier AE, Place NJ. Anti-Müllerian hormone concentration measured before gonadotropin stimulation is associated with quality of subsequent ovarian response in the cheetah (Acinonyx jubatus) and domestic cat (Felis catus)†. Biol Reprod. 2025 Apr 13;112(4):754-766. doi: 10.1093/biolre/ioaf025. PMID: 39903683.
Driancourt MA, Comizzoli P, Brito LFC. Celebrating a milestone and looking at the future of Theriogenology. Theriogenology. 2025 Mar 1;234:151-152. doi: 10.1016/j.theriogenology.2024.12.013. Epub 2024 Dec 13. PMID: 39700756.
Sosnicki DM, Travis AJ, Comizzoli P. In vitro exposure to epididymal extracellular vesicles from normospermic domestic cats improves developmental potential of sperm from teratospermic cats. Front Vet Sci. 2025 Jan 17;12:1547175. doi: 10.3389/fvets.2025.1547175. PMID: 39896847; PMCID: PMC11783848.
Lima GL, Brasil AV, Silva AM, Antunes JMAP, Comizzoli P, Silva AR. Characterization of the Population of Ovarian Preantral Follicles in Juvenile Six-Banded Armadillos Infected or Not by Mycobacterium leprae. Vet Sci. 2025 Jan 9;12(1):37. doi: 10.3390/vetsci12010037. PMID: 39852911; PMCID: PMC11768727.

2024

Sosnicki DM, Travis AJ, Comizzoli P. Extracellular vesicles are involved in the paracrine communication between epithelial cells in different regions of the domestic cat epididymis†. Biol Reprod. 2024 Nov 11;111(5):1056-1070. doi: 10.1093/biolre/ioae129. PMID: 39190878.
Hutchinson AM, Appeltant R, Burdon T, Bao Q, Bargaje R, Bodnar A, Chambers S, Comizzoli P, Cook L, Endo Y, Harman B, Hayashi K, Hildebrandt T, Korody ML, Lakshmipathy U, Loring JF, Munger C, Ng AHM, Novak B, Onuma M, Ord S, Paris M, Pask AJ, Pelegri F, Pera M, Phelan R, Rosental B, Ryder OA, Sukparangsi W, Sullivan G, Tay NL, Traylor-Knowles N, Walker S, Weberling A, Whitworth DJ, Williams SA, Wojtusik J, Wu J, Ying QL, Zwaka TP, Kohler TN. Advancing stem cell technologies for conservation of wildlife biodiversity. Development. 2024 Oct 15;151(20):dev203116. doi: 10.1242/dev.203116. Epub 2024 Oct 9. PMID: 39382939; PMCID: PMC11491813.
Silva AMD, Pereira AG, Bezerra LGP, Brasil AV, Pereira AF, de Oliveira MF, Rodrigues APR, Ñaupas LVS, Comizzoli P, Silva AR. Synergistic effects of glial cell line-derived neurotrophic factor and base-medium on in vitro culture of testicular tissue derived from prepubertal collared peccary. Cell Biol Int. 2024 Sep;48(9):1364-1377. doi: 10.1002/cbin.12203. Epub 2024 Jun 21. PMID: 39007507.
Sosnicki DM, Travis AJ, Comizzoli P. Extracellular vesicles are involved in the paracrine communication between epithelial cells in different regions of the domestic cat epididymis. Biol Reprod. 2024 Aug 27:ioae129. doi: 10.1093/biolre/ioae129. Epub ahead of print. PMID: 39190878.
Lee PC, Comizzoli P. Microwave-assisted dehydration, long-term storage at non-freezing temperatures, and rehydration of cat germinal vesicles†. Biol Reprod. 2024 Aug 15;111(2):312-321. doi: 10.1093/biolre/ioae060. PMID: 38637297; PMCID: PMC11327313.
Hagedorn M, Parenti LR, Craddock RA, Comizzoli P, Mabee P, Meinke B, Wolf SM, Bischof JC, Sandlin RD, Tessier SN, Toner M. Safeguarding Earth’s biodiversity by creating a lunar biorepository. Bioscience. 2024 Jul 31;74(8):561-566. doi: 10.1093/biosci/biae058. PMID: 39229623; PMCID: PMC11367668.
DeCandia AL, Adeduro L, Thacher P, Crosier A, Marinari P, Bortner R, Garelle D, Livieri T, Santymire R, Comizzoli P, Maslanka M, Maldonado JE, Koepfli KP, Muletz-Wolz C, Bornbusch SL. Gut bacterial composition shows sex-specific shifts during breeding season in ex situ managed black-footed ferrets. J Hered. 2024 Jul 10;115(4):385-398. doi: 10.1093/jhered/esad065. PMID: 37886904.
Bezerra LGP, Oliveira REM, Comizzoli P, Silva AR. Collection, Handling, and Preservation of Wild Bird Semen: Current Status, Challenges, and Perspectives. Biopreserv Biobank. 2024 Jun;22(3):191-210. doi: 10.1089/bio.2023.0053. Epub 2023 Sep 12. PMID: 37699234.
Ali N, Amelkina O, Santymire RM, Koepfli KP, Comizzoli P, Vazquez JM. Semen proteome and transcriptome of the endangered black-footed ferret (Mustela nigripes) show association with the environment and fertility outcome. Sci Rep. 2024 Mar 25;14(1):7063. doi: 10.1038/s41598-024-57096-w. PMID: 38528039; PMCID: PMC10963785.
Bornbusch SL, Bamford A, Thacher P, Crosier A, Marinari P, Bortner R, Garelle D, Livieri T, Santymire R, Comizzoli P, Maslanka M, Maldonado JE, Koepfli KP, Muletz-Wolz CR, DeCandia AL. Markers of fertility in reproductive microbiomes of male and female endangered black-footed ferrets (Mustela nigripes). Commun Biol. 2024 Feb 23;7(1):224. doi: 10.1038/s42003-024-05908-0. Erratum in: Commun Biol. 2024 Sep 10;7(1):1110. doi: 10.1038/s42003-024-06793-3. PMID: 38396133; PMCID: PMC10891159.
Cowl VB, Comizzoli P, Appeltant R, Bolton RL, Browne RK, Holt WV, Penfold LM, Swegen A, Walker SL, Williams SA. Cloning for the Twenty-First Century and Its Place in Endangered Species Conservation. Annu Rev Anim Biosci. 2024 Feb 15;12:91-112. doi: 10.1146/annurev-animal-071423-093523. Epub 2023 Nov 21. PMID: 37988633.
Tennenbaum SR, Bortner R, Lynch C, Santymire R, Crosier A, Santiestevan J, Marinari P, Pukazhenthi BS, Comizzoli P, Hawkins MTR, Maldonado JE, Koepfli KP, vonHoldt BM, DeCandia AL. Epigenetic changes to gene pathways linked to male fertility in ex situ black-footed ferrets. Evol Appl. 2024 Jan 26;17(1):e13634. doi: 10.1111/eva.13634. PMID: 38283602; PMCID: PMC10818088.
Bezerra LGP, Silva AM, Dantas MRT, Dos Santos RP, Moreira SSJ, Pereira AG, de Oliveira MF, Comizzoli P, Silva AR. Development of assays for the characterization of sperm motility parameters, viability, and membrane integrity in the epididymis and vas deferens of the greater rhea (Rhea americana). Anim Reprod. 2024 Jan 5;20(4):e20230113. doi: 10.1590/1984-3143-AR2023-0113. PMID: 38213765; PMCID: PMC10782801.

Cosgrove

2026

Pirtz MG, Flesken-Nikitin A, Ralston CQ, Phuong DJ, Wang N, Chu T, Chen S, Zheng Y, Schmoeckel E, Yemelyanova A, Shih IM, Danko CG, Cosgrove BD, Nikitin AY. Cross-species analysis links cell-cell communication rewiring to NOTCH2 during serous endometrial carcinogenesis. bioRxiv [Preprint]. 2026 Sep 20:2026.09.01.748540. doi: 10.64898/2026.09.01.748540. PMID: 42779706; PMCID: PMC13596177.
Hoang P, McKellar DW, Kowalczewski A, Mai NY, Chai M, Lian XL, Zheng Y, Amack J, Tucker N, De Vlaminck I, Yang H, Cosgrove BD, Ma Z. Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids. Adv Sci (Weinh). 2026 May;13(30):e15661. doi: 10.1002/advs.202515661. Epub 2026 Mar 16. PMID: 41837870; PMCID: PMC13248853.
Ralston CQ, Flesken-Nikitin A, Fu DJ, Ashe CS, Harlan BA, Hossain MM, Wang DK, Yemelyanova A, Schmoeckel E, Godwin AK, Mayr D, Cosgrove BD, Yu Nikitin A. Comparative single-cell atlases reveal injury-driven tubal epithelial regeneration as a window for ovarian carcinoma initiation. bioRxiv [Preprint]. 2026 Mar 30:2026.03.26.714557. doi: 10.64898/2026.03.26.714557. PMID: 41958997; PMCID: PMC13060286.

2025

Xue S, Benvie AM, Blum JE, Cosgrove BD, Thalacker-Mercer AE, Berry DC. PDGFRβ signaling restrains myocyte function to limit the regenerative capacity of skeletal muscle. J Clin Invest. 2025 Dec 16;136(4):e188272. doi: 10.1172/JCI188272. PMID: 41697742; PMCID: PMC12904705.
Flesken-Nikitin A, Pirtz MG, Ashe CS, Ellenson LH, Yemelyanova A, Cosgrove BD, Nikitin AY. Cell state dynamics during early stages of serous endometrial carcinoma. J Pathol. 2025 Nov;267(3):289-303. doi: 10.1002/path.6470. Epub 2025 Sep 9. PMID: 40923619.
Li S, Agudelo Garcia PA, Aliferis C, Becich MJ, Calyeca J, Cosgrove BD, Elisseeff J, Farzad N, Fertig EJ, Glass C, Gu L, Hu Q, Ji Z, Königshoff M, LeBrasseur NK, Li D, Ma A, Ma Q, Menon V, Mitchell JT, Mora AL, Nagaraj S, Nelson AC, Niedernhofer LJ, Rojas M, Taha HB, Wang J, Wang S, Wu PH, Xie J, Xu M, Yu M, Zhang X, Zhao Y, Adams PD, Aguayo-Mazzucato C, Baker DJ, Benz C, Bernlohr DA, Bueno M, Chen J, Childs BG, Chuang JH, Chung D, Dileepan M, Ding L, Dong M, Duncan F, Enninful A, Flynn WF, Franco AC, Furman D, Garovic V, Halene S, Herman AB, Hertzel AV, Iwasaki K, Jeon H, Kang JW, Karmakar S, Kirkland JL, Korstanje R, Kummerfeld E, Lee JH, Liu Y, Lu Y, Lugo-Martinez J, Martini H, Melov S, Musi N, Passos JF, Peters ST, Rahman I, Ramasamy R, Rindone AN, Robbins PD, Robson P, Rodriguez-Lopez J, Rosas L, Rosenthal N, Schafer MJ, Schilling B, Schmidt EL, Schneider K, Sengupta K, Shu J, So PTC, Sun L, Tchkonia T, Teneche MG, Vanegas N, Wang J, Xie J, Yin S, Zhang K, Zhu Q, Fan R; SenNet Consortium. Advancing biological understanding of cellular senescence with computational multiomics. Nat Genet. 2025 Oct;57(10):2381-2394. doi: 10.1038/s41588-025-02314-y. Epub 2025 Sep 15. PMID: 40954249.
Hoang P, McKellar DW, Kowalczewski A, Mai NY, Chai M, Lian XL, Zheng Y, Amack J, Tucker N, De Vlaminck I, Yang H, Cosgrove BD, Ma Z. Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids. bioRxiv [Preprint]. 2025 Sep 19:2025.09.17.676874. doi: 10.1101/2025.09.17.676874. PMID: 41000917; PMCID: PMC12458260.
Phuong DJ, Pirtz MG, Ralston CQ, Cosgrove BD, Schimenti JC, Flesken-Nikitin A, Nikitin AY. Aggressive Serous Carcinomas of the Female Reproductive Tract: Cancer-Prone Cell States and Genetic Drivers. Cancers (Basel). 2025 Feb 11;17(4):604. doi: 10.3390/cancers17040604. PMID: 40002199; PMCID: PMC11852459.

2024

Walter LD, Orton JL, Ntekas I, Fong EHH, Maymi VI, Rudd BD, De Vlaminck I, Elisseeff JH, Cosgrove BD. Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states. Nat Aging. 2024 Dec;4(12):1862-1881. doi: 10.1038/s43587-024-00756-3. Epub 2024 Nov 22. PMID: 39578558; PMCID: PMC11645289.
Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Author Correction: Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Nov 20;15(1):10053. doi: 10.1038/s41467-024-54465-x. Erratum for: Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39567528; PMCID: PMC11579345.
Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39366996; PMCID: PMC11452611.

Danko

2026

Zeng X, Barshad G, Hassett R, Rice EJ, Danko CG, Siepel A, Zhao Y. A comparative analysis of promoter-proximal pausing reveals kinetic and distributional dimensions of variation. Res Sq [Preprint]. 2026 Oct 6:rs.3.rs-11000542. doi: 10.21203/rs.3.rs-11000542/v1. PMID: 42926976; PMCID: PMC13692615.
Pirtz MG, Flesken-Nikitin A, Ralston CQ, Phuong DJ, Wang N, Chu T, Chen S, Zheng Y, Schmoeckel E, Yemelyanova A, Shih IM, Danko CG, Cosgrove BD, Nikitin AY. Cross-species analysis links cell-cell communication rewiring to NOTCH2 during serous endometrial carcinogenesis. bioRxiv [Preprint]. 2026 Sep 20:2026.09.01.748540. doi: 10.64898/2026.09.01.748540. PMID: 42779706; PMCID: PMC13596177.
Munn PR, Chia J, Danko CG. Accurate de novo transcription unit annotation from run-on and sequencing data. PLoS Comput Biol. 2026 Aug 3;22(8):e1014559. doi: 10.1371/journal.pcbi.1014559. PMID: 42546039; PMCID: PMC13460741.
Jiang K, Haley EK, Barshad G, He A, Rogic A, Rice E, Sudman M, Thompson SD, Murphy DA, Fu Y, Ponder L, Munoz MD, Kolachala P, Prahalad S, Gaffney PM, Danko CG, Jarvis JN. Functional and computational interrogation of juvenile idiopathic arthritis risk loci in CD4+ T cells. HGG Adv. 2026 Jul 9;7(3):100619. doi: 10.1016/j.xhgg.2026.100619. Epub 2026 Apr 28. PMID: 42057421; PMCID: PMC13214527.
Zeng X, Barshad G, Hassett R, Rice EJ, Danko CG, Siepel A, Zhao Y. A comparative analysis of promoter-proximal pausing reveals kinetic and distributional dimensions of variation. bioRxiv [Preprint]. 2026 Jun 4:2026.06.01.729264. doi: 10.64898/2026.06.01.729264. PMID: 42282755; PMCID: PMC13251929.
Tanis S, Simon LE, Alexander AK, Horan TS, Carro MLM, Bonnett SJ, Xie A, Ben-Shlomo R, Owens CE, Danko CG, Lujic J, Cohen PE. Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2517498123. doi: 10.1073/pnas.2517498123. Epub 2026 Apr 7. PMID: 41945432; PMCID: PMC13080027.
Zhang Z, Fan X, Zhong J, Jia L, Han Y, Yang C, He Z, Li X, Yau ST, Wu R, Danko CG, Wang Z. An end-to-end generalizable deep learning framework to comprehensively analyze transcriptional regulation. Nat Commun. 2026 Apr 1;17(1):4708. doi: 10.1038/s41467-026-70070-6. PMID: 41922356; PMCID: PMC13212934.
Chang HY, McMurry SE, Ma S, Heinke CL, Mansour CA, Schwab SMT, Danko CG, Lee SS. Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in Caenorhabditis elegans. PLoS Biol. 2026 Feb 20;24(2):e3003639. doi: 10.1371/journal.pbio.3003639. PMID: 41719228; PMCID: PMC12923026.
Chivu AG, Basso BA, Abuhashem A, Leger MM, Barshad G, Rice EJ, Vill AC, Wong W, Chou SP, Chovatiya G, Brady R, Smith JJ, Wikramanayake AH, Arenas-Mena C, Brito IL, Ruiz-Trillo I, Hadjantonakis AK, Lis JT, Lewis JJ, Danko CG. Evolution of promoter-proximal pausing enabled a new layer of transcription control. Nat Struct Mol Biol. 2026 Feb;33(2):282-292. doi: 10.1038/s41594-025-01718-y. Epub 2025 Dec 15. PMID: 41398462; PMCID: PMC13696009.

2025

Barshad G, Danko CG. Revisiting models of enhancer-promoter communication in gene regulation. Genome Res. 2025 Jun 2;35(6):1277-1286. doi: 10.1101/gr.278389.123. PMID: 40456606; PMCID: PMC12129020.
Chang HY, McMurry SE, Ma S, Mansour CA, Schwab SMT, Danko CG, Lee SS. Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in Caenorhabditis elegans. bioRxiv [Preprint]. 2025 Mar 14:2025.03.11.642714. doi: 10.1101/2025.03.11.642714. PMID: 40161833; PMCID: PMC11952391.
Munn PR, Chia J, Danko CG. Accurate de novo transcription unit annotation from run-on and sequencing data. bioRxiv [Preprint]. 2025 Feb 17:2025.02.12.637853. doi: 10.1101/2025.02.12.637853. PMID: 40027686; PMCID: PMC11870431.
He AY, Palamuttam NP, Danko CG. Training deep learning models on personalized genomic sequences improves variant effect prediction. bioRxiv [Preprint]. 2025 Feb 15:2024.10.15.618510. doi: 10.1101/2024.10.15.618510. PMID: 39463940; PMCID: PMC11507713.

2024

Wang Z, Song A, Tao B, Miao M, Luo YQ, Wang J, Yin Z, Xiao R, Zhou X, Shang XY, Hu S, Liang K, Danko CG, Chen FX. The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release. Mol Cell. 2024 Dec 19;84(24):4824-4842.e7. doi: 10.1016/j.molcel.2024.10.046. Epub 2024 Nov 26. PMID: 39603240.
Wen W, Zhong J, Zhang Z, Jia L, Chu T, Wang N, Danko CG, Wang Z. dHICA: a deep transformer-based model enables accurate histone imputation from chromatin accessibility. Brief Bioinform. 2024 Sep 23;25(6):bbae459. doi: 10.1093/bib/bbae459. PMID: 39316943; PMCID: PMC11421843.
Vill AC, Rice EJ, De Vlaminck I, Danko CG, Brito IL. Precision run-on sequencing (PRO-seq) for microbiome transcriptomics. Nat Microbiol. 2024 Jan;9(1):241-250. doi: 10.1038/s41564-023-01558-w. Epub 2024 Jan 3. PMID: 38172625; PMCID: PMC11059318.

Das

2026

O’Donnell EC, Lim J, Das A. Extreme Protein Longevity in the Ovary: Implications for Reproductive Aging. Biol Reprod. 2026 Nov 2:ioag245. doi: 10.1093/biolre/ioag245. Epub ahead of print. PMID: 42969938.
Coon AD, Das A. CENP-C in two acts: Dynamic roles in male meiotic centromere assembly. J Cell Biol. 2026 Sep 7;225(9):e202607032. doi: 10.1083/jcb.202607032. Epub 2026 Aug 25. PMID: 42640251.
McKane AM, Chauhan IV, Miller D, Ghosh S, Das A, de Mestre AM. Chromosomal chaos: understanding aneuploidy associated with assisted reproductive technologies. J Equine Vet Sci. 2026 Sep;164:106053. doi: 10.1016/j.jevs.2026.106053. Epub 2026 Jun 17. PMID: 42309330.

2025

Tower CA, Manske G, Ferrell EL, Anbarci DN, Jorgensen K, Ma B, Aboelenain M, Ranjan R, Chakraborty S, Moritz L, Das A, Boiani M, Black BE, Chavez S, Marsh EE, Shikanov A, Schindler K, Chen X, Hammoud SS. Maternal CENP-C restores centromere symmetry in mammalian zygotes to ensure proper chromosome segregation. Dev Cell. 2025 Sep 24:S1534-5807(25)00537-4. doi: 10.1016/j.devcel.2025.08.017. Epub ahead of print. PMID: 40997799; PMCID: PMC12479092.

2024

Joshi JN, Changela N, Mahal L, Jang J, Defosse T, Wang LI, Das A, Shapiro JG, McKim K. Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes. Mol Biol Cell. 2024 Aug 1;35(8):ar105. doi: 10.1091/mbc.E24-02-0067. Epub 2024 Jun 12. PMID: 38865189; PMCID: PMC11321039.

Daugherity

2026

Outouil M, Daugherity EK, Warnick LD, Perry PJ. Evaluation of Short-Term Stall Size Housing on the Behavior and Welfare of Domestic Horses (Equus caballus). J Am Assoc Lab Anim Sci. 2026 Apr 1;65(4):1-10. doi: 10.30802/AALAS-JAALAS-25-152. Epub ahead of print. PMID: 42014105; PMCID: PMC13446403.

de Mestre

2026

Renaudin C, Omyla K, De Castro T, Ratliff B, Bartholomew S, Dechant J, Vapniarsky N, Woolard K, Kovacs S, Bozorgmanesh R, de Mestre AM, Dini P. Ultrasonographic assessment of in utero fetal presentation, position and posture can be essential: case report. J Equine Vet Sci. 2026 Nov;166:106105. doi: 10.1016/j.jevs.2026.106105. Epub 2026 Aug 3. PMID: 42546861.
McKane AM, Chauhan IV, Miller D, Ghosh S, Das A, de Mestre AM. Chromosomal chaos: understanding aneuploidy associated with assisted reproductive technologies. J Equine Vet Sci. 2026 Sep;164:106053. doi: 10.1016/j.jevs.2026.106053. Epub 2026 Jun 17. PMID: 42309330.
Mouncey R, de Mestre AM, Arango-Sabogal JC, Verheyen KL. Born to run? Associations between gestational and early-life exposures and later-life performance outcomes in Thoroughbreds. Equine Vet J. 2026 Jul;58(4):1071-1081. doi: 10.1111/evj.70084. Epub 2025 Aug 25. PMID: 40851510; PMCID: PMC13244176.

Jaworska J, Tobolski D, Salem SE, Ropka-Molik K, Ząbek T, Szmatoła T, Kahler A, Wocławek-Potocka I, Piórkowska K, de Mestre AM. Comparative analysis of the transcriptome and methylome in distinct trophoblast populations at the time of embryo implantation in mares. BMC Genomics. 2026 Apr 7;27(1):492. doi: 10.1186/s12864-026-12822-8. PMID: 41942885; PMCID: PMC13188566.
Lawson JM, Verheyen KL, Laroucau K, Bryan JS, Smith KC, Foote AK, de Mestre AM. Umbilical cord torsion abortion: the gross and histological features of affected umbilical cords and fetal membranes. Theriogenology. 2026 Mar 1;252:117771. doi: 10.1016/j.theriogenology.2025.117771. Epub 2025 Nov 21. PMID: 41338002.
Fehin B, Scott CJ, Arango-Sabogal JC, de Mestre AM, Mouncey R. Associations between endometrial swab bacteriology and cytology findings and live foal rates in Thoroughbred broodmares in the United Kingdom. Equine Vet J. 2026 Mar;58(2):348-358. doi: 10.1111/evj.70086. Epub 2025 Sep 1. PMID: 40888035; PMCID: PMC12892376.

2025

Mouncey R, de Mestre AM, Verheyen KL. Born to run? Racing and training outcomes, population dynamics and traceability of a Thoroughbred birth cohort. Vet Rec. 2025 Oct 4;197(7):e5777. doi: 10.1002/vetr.5777. Epub 2025 Sep 26. PMID: 41000051; PMCID: PMC12494123.
Fehin B, Scott CJ, Arango-Sabogal JC, de Mestre AM, Mouncey R. Associations between endometrial swab bacteriology and cytology findings and live foal rates in Thoroughbred broodmares in the United Kingdom. Equine Vet J. 2025 Sep 1. doi: 10.1111/evj.70086. Epub ahead of print. PMID: 40888035.
Mouncey R, de Mestre AM, Arango-Sabogal JC, Verheyen KL. Born to run? Associations between gestational and early-life exposures and later-life performance outcomes in Thoroughbreds. Equine Vet J. 2025 Aug 25. doi: 10.1111/evj.70084. Epub ahead of print. PMID: 40851510.

2024

Mouncey R, Arango-Sabogal JC, de Mestre A, Verheyen KL. Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom. Equine Vet J. 2024 Sep;56(5):892-901. doi: 10.1111/evj.14038. Epub 2023 Dec 26. PMID: 38146768.
Lawson JM, Salem SE, Miller D, Kahler A, van den Boer WJ, Shilton CA, Sever T, Mouncey RR, Ward J, Hampshire DJ, Foote AK, Bryan JS, Juras R, Pynn OD, Davis BW, Bellone RR, Raudsepp T, de Mestre AM. Naturally occurring horse model of miscarriage reveals temporal relationship between chromosomal aberration type and point of lethality. Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2405636121. doi: 10.1073/pnas.2405636121. Epub 2024 Aug 5. PMID: 39102548; PMCID: PMC11331123.
Lawson JM, Verheyen K, Smith KC, Bryan JS, Foote AK, de Mestre AM. The equine umbilical cord in clinically healthy pregnancies. Equine Vet J. 2024 Jul;56(4):742-750. doi: 10.1111/evj.14055. Epub 2024 Jan 14. PMID: 38219774.
Lawson JM, Shilton CA, Lindsay-McGee V, Psifidi A, Wathes DC, Raudsepp T, de Mestre AM. Does inbreeding contribute to pregnancy loss in Thoroughbred horses? Equine Vet J. 2024 Jul;56(4):711-718. doi: 10.1111/evj.14057. Epub 2024 Jan 14. PMID: 38221707.
Wagner B, Babasyan S, Wilford S, Robbin MG, de Mestre AM. Monoclonal antibodies for equine CD25 improve detection of regulatory T cells in horses. Vet Immunol Immunopathol. 2024 Aug;274:110790. doi: 10.1016/j.vetimm.2024.110790. Epub 2024 Jun 6. PMID: 38901326.
Sielhorst J, Koether K, Volkmann N, Blanco M, Vicioso R, Baade S, Kemper N, de Mestre AM, Sieme H. Occurrence of ultrasonographic assessed placental abnormalities, treatments, pregnancy outcome, and subsequent fertility on a large warmblood stud farm: A retrospective field study. J Equine Vet Sci. 2024 May 1;137:105076. doi: 10.1016/j.jevs.2024.105076. Epub ahead of print. PMID: 38697370.
Mouncey R, Arango-Sabogal JC, Rathbone P, Scott CJ, de Mestre AM. Prevalence of Microbial Isolates Cultured from Endometrial Swab Samples Collected from United Kingdom Thoroughbred Mares from 2014 to 2020. Vet Sci. 2024 Feb 9;11(2):82. doi: 10.3390/vetsci11020082. PMID: 38393100; PMCID: PMC10891641.

de Vlaminck

2026

Zuela-Sopilniak N, Morival JLP, Ntekas I, Elpers MA, Agarwal R, Henretta SJ, Odell JD, De Vlaminck I, Lammerding J. Reducing Nuclear Rupture Rescues Gene Expression and Survival in LMNA-DCM. Circ Res. 2026 Oct 23;139(10):e327744. doi: 10.1161/CIRCRESAHA.125.327744. Epub 2026 Sep 25. PMID: 42788248; PMCID: PMC13682672.
Schlesinger MS, Dadhania DM, Lee JR, De Vlaminck I. Precision monitoring of kidney transplant health via cell-free DNA and RNA. Curr Opin Organ Transplant. 2026 Aug 25. doi: 10.1097/MOT.0000000000001309. Epub ahead of print. PMID: 42638477.
Huang L, Sanketi B, Mantri M, Chen Y, Wang C, Tran T, De Vlaminck I, Kurpios NA. A NON-CANONICAL ROLE FOR NOTCH3 IN BUILDING THE INTESTINAL LYMPHATIC NICHE. bioRxiv [Preprint]. 2026 Aug 14:2026.08.13.742813. doi: 10.64898/2026.08.13.742813. PMID: 42845378; PMCID: PMC13640725.
Qin Q, Ostendorf L, Wells SL, Gao C, Tran M, Alikhan FM, Zhang X, Chewcharat A, Rider RS, Prell SA, Chowdhury RB, Weins A, Shah SI, Mistry K, Bowman T, Villani AC, LeBoeuf NR, Selamet U, Ravi KS, Sharon E, Leaf DE, Moledina DG, Sise ME, De Vlaminck I, Rao DA, Wei K, Gupta S. Spatial Transcriptomics and Mechanisms of Immune Checkpoint Inhibitor-Associated Interstitial Nephritis. Kidney Int Rep. 2026 Aug 5;11(10):107007. doi: 10.1016/j.ekir.2026.107007. PMID: 42756960; PMCID: PMC13583950.
Stephanou A, Shui B, Mische D, Byron M, Katt WP, Chan M, Grenier JK, De Vlaminck I, Duhamel GE, Gujral TS, Sethupathy P, Peralta S. Neuroepithelial reprogramming and ERBB vulnerability in canine acanthomatous ameloblastoma. Mol Ther Oncol. 2026 Jul 22;34(3):201300. doi: 10.1016/j.omton.2026.201300. PMID: 42602547; PMCID: PMC13474083.
Gaudio HA, Bliss A, Loy CJ, Eweis-LaBolle D, Gardella AE, De Vlaminck I. Benchmarking large language models for cell-free RNA diagnostic biomarker discovery. Nat Commun. 2026 Jun 11;17(1):7429. doi: 10.1038/s41467-026-74077-x. PMID: 42276999; PMCID: PMC13408832.
Hoang P, McKellar DW, Kowalczewski A, Mai NY, Chai M, Lian XL, Zheng Y, Amack J, Tucker N, De Vlaminck I, Yang H, Cosgrove BD, Ma Z. Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids. Adv Sci (Weinh). 2026 May;13(30):e15661. doi: 10.1002/advs.202515661. Epub 2026 Mar 16. PMID: 41837870; PMCID: PMC13248853.
Ntekas I, Takayasu L, McKellar DW, Grodner B, Holdener C, Schweitzer P, Park YS, Sauthoff M, Shi Q, Brito IL, De Vlaminck I. Spatial transcriptomics maps host-gut microbiome biogeography at high resolution. Nat Microbiol. 2026 May;11(5):1193-1204. doi: 10.1038/s41564-026-02286-7. Epub 2026 Mar 6. PMID: 41792309; PMCID: PMC13171632.
Stephanou A, Mantri M, Shankaranarayanan D, Li C, Lagman M, Xiang J, Pan C, Sun Y, Muthukumar T, Machaca K, De Vlaminck I, Suthanthiran M. Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers. Hum Immunol. 2026 Apr;87(4):111687. doi: 10.1016/j.humimm.2026.111687. Epub 2026 Feb 13. PMID: 41690207; PMCID: PMC13478930.
Holdener C, De Vlaminck I. Smoothie: efficient inference and integration of spatial co-expression networks from denoised spatial transcriptomics data. Commun Biol. 2026 Mar 26;9(1):459. doi: 10.1038/s42003-026-09898-z. PMID: 41888598; PMCID: PMC13031863.
Loy C, Agun G, Maurer K, Vilaseca AB, Potapova D, Jacobson CA, Ritz J, De Vlaminck I. Cell-free RNA Signatures Derived from the Tumor Microenvironment Predict Outcomes of CAR-T Therapy in Large B Cell Lymphoma. medRxiv [Preprint]. 2026 Mar 18:2026.03.16.26348550. doi: 10.64898/2026.03.16.26348550. PMID: 41891043; PMCID: PMC13015665.
Bliss A, Loy CJ, Kim J, Shimizu C, Lenz JS, Belcher E, Tremoulet AH, Burns JC, De Vlaminck I. Minimal correlation but complementary diagnostic utility for plasma cell-free RNA and proteins. Commun Med (Lond). 2026 Mar 13;6(1):252. doi: 10.1038/s43856-026-01489-7. PMID: 41826701; PMCID: PMC13125234.
Jiang S, Freedman J, Mantri M, Maymi V, Leddon SA, Schweitzer P, Bhandari S, Holdener C, Ntekas I, Vollmers C, Flyak AI, Fowell DJ, Rudd BD, De Vlaminck I. A temporal and spatial atlas of adaptive immune responses in the lymph node following viral infection. Proc Natl Acad Sci U S A. 2026 Feb 3;123(5):e2504742123. doi: 10.1073/pnas.2504742123. Epub 2026 Jan 26. PMID: 41587309; PMCID: PMC12867689.
Bakhle K, Nelissen S, Li L, Ntekas I, De Vlaminck I, Peralta S, Miller AD, Dongre A. Epithelial-mesenchymal plasticity and immunosuppression in canine carcinomas reveals cross-species upregulation of CD109. Commun Biol. 2026 Jan 22;9(1):303. doi: 10.1038/s42003-026-09587-x. PMID: 41571773; PMCID: PMC12929570.
Shimizu C, Pérez Pomares JM, Loy CJ, De Vlaminck I, Tremoulet AH, Ruiz-Villalba A, Burns JC. Pathology of the Coronary Arteries and Myocardium in Kawasaki Disease. Annu Rev Pathol. 2026 Jan;21(1):349-371. doi: 10.1146/annurev-pathmechdis-111523-023453. Epub 2025 Oct 28. PMID: 41150874.

2025

Djomnang LK, Srivatana V, Mzava O, Belcher E, Westblade LF, Dadhania DM, Li C, De Vlaminck I, Lee JR. A peritoneal effluent sequencing assay that removes environmental DNA contamination in peritoneal dialysis patients. Clin Kidney J. 2025 Dec 26;19(1):sfaf358. doi: 10.1093/ckj/sfaf358. PMID: 41522692; PMCID: PMC12780757.
De Vlaminck I, Mzava O, Djomnang LA, Cheng A, Gomez-Escobar L, Lenz J, Belcher E, Schenck E. Metagenomic Cell-free DNA Sequencing for Treatment Monitoring in Sepsis. Res Sq [Preprint]. 2025 Dec 22:rs.3.rs-8148988. doi: 10.21203/rs.3.rs-8148988/v1. PMID: 41510275; PMCID: PMC12776501.
Park J, Sun S, Agarwal R, Stephanou A, Poon MLS, Maeng H, Lancaster P, De Vlaminck I, Butcher J. Spatiotemporal Atlas of Heart Development Reveals Blood-Flow-Dependent Cellular, Structural, Metabolic, and Spatial Remodeling. bioRxiv [Preprint]. 2025 Dec 12:2025.12.09.693024. doi: 10.64898/2025.12.09.693024. PMID: 41427371; PMCID: PMC12714022.
Qin Q, Ostendorf L, Wells SL, Gao C, Tran M, Alikhan FM, Zhang X, Chewcharat A, Rider RS, Prell SA, Chowdhury RB, Weins A, Shah SI, Mistry K, Bowman T, Villani AC, LeBoeuf NR, Selamet U, Ravi KS, Sharon E, Leaf DE, Moledina DG, Sise ME, De Vlaminck I, Rao DA, Wei K, Gupta S. Spatial Transcriptomics Identify T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis. bioRxiv [Preprint]. 2025 Nov 3:2025.10.31.685702. doi: 10.1101/2025.10.31.685702. PMID: 41280053; PMCID: PMC12637725.
Shimizu C, Pérez Pomares JM, Loy CJ, De Vlaminck I, Tremoulet AH, Ruiz-Villalba A, Burns JC. Pathology of theCoronary Arteries and Myocardium in Kawasaki Disease. Annu Rev Pathol. 2025 Oct 28. doi: 10.1146/annurev-pathmechdis-111523-023453. Epub ahead of print. PMID: 41150874.

Hemberg M, Marini F, Ghazanfar S, Al Ajami A, Abassi N, Anchang B, Benayoun BA, Cao Y, Chen K, Cuesta-Astroz Y, DeBruine Z, Dendrou CA, De Vlaminck I, Imkeller K, Korsunsky I, Lederer AR, Li JJ, Meysman P, Miller CL, Mullan KA, Ohler U, Panwar P, Patikas N, Schuck J, Siu JHY, Triche TJ Jr, Tsankov A, van der Laan SW, Yajima M, Yang J, Zanini F, Jelic I. Insights, opportunities, and challenges provided by large cell atlases. Genome Biol. 2025 Oct 20;26(1):358. doi: 10.1186/s13059-025-03771-8. PMID: 41116172; PMCID: PMC12536537.
Mzava O, Agun GF, Loy CJ, Gonzalez-Bocco IH, Djomnang Kounatse LA, Bliss A, Wells SL, Lenz J, Belcher E, Chen K, Koo S, Baden LR, Chu T, Cheng MP, Ritz J, Gupta S, De Vlaminck I. Urine Cell-Free RNA vs Plasma Cell-Free RNA for Monitoring of Kidney Injury and Immune Complications. Clin Chem. 2025 Oct 3;71(10):1058-1066. doi: 10.1093/clinchem/hvaf082. PMID: 40796157; PMCID: PMC12490885.
Hoang P, McKellar DW, Kowalczewski A, Mai NY, Chai M, Lian XL, Zheng Y, Amack J, Tucker N, De Vlaminck I, Yang H, Cosgrove BD, Ma Z. Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids. bioRxiv [Preprint]. 2025 Sep 19:2025.09.17.676874. doi: 10.1101/2025.09.17.676874. PMID: 41000917; PMCID: PMC12458260.
Zuela-Sopilniak N, Morival JLP, Ntekas I, Elpers MA, Agarwal R, Henretta SJ, Odell JD, De Vlaminck I, Lammerding J. Nuclear envelope rupture in cardiomyocytes orchestrates early transcriptomic changes and immune activation in LMNA -DCM that are reversed by LINC complex disruption. bioRxiv [Preprint]. 2025 Sep 15:2024.06.11.598511. doi: 10.1101/2024.06.11.598511. PMID: 38915720; PMCID: PMC11195185.
Holdener C, Jiang S, Sutherland DM, Griswold KA, Dermody TS, Parker JSL, De Vlaminck I. Spatial Transcriptomics to Study Virus-Host Interactions. Annu Rev Virol. 2025 Sep;12(1):379-399. doi: 10.1146/annurev-virology-092623-104926. Epub 2025 Jun 16. PMID: 40523107.
Jones J, García-Martínez KY, Lee YY, Rhee M, Nath RR, Takahashi S, Grodner B, De Vlaminck I, Leifer CA, Brito IL. Gut commensal microbiota drive tailored macrophage responses. Cell Rep. 2025 Aug 26;44(8):116157. doi: 10.1016/j.celrep.2025.116157. Epub 2025 Aug 18. PMID: 40828655.
Gardella AE, Eweis-LaBolle D, Loy CJ, Belcher ED, Lenz JS, Franconi CJ, Scofield SY, Grimson A, Hanson MR, De Vlaminck I. Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome. Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2507345122. doi: 10.1073/pnas.2507345122. Epub 2025 Aug 11. PMID: 40789036; PMCID: PMC12377778.
Loy CJ, Wang H, Kim J, Shimizu C, Lenz J, Belcher E, Tremoulet AH, Burns JC, De Vlaminck I. Molecular characterization of Kawasaki disease subgroups using cell-free RNA profiling. Sci Rep. 2025 Aug 14;15(1):29799. doi: 10.1038/s41598-025-15843-7. PMID: 40813796; PMCID: PMC12354920.
Tabula Microcebus Consortium; Ezran C, Liu S, Chang S, Ming J, Botvinnik O, Penland L, Tarashansky A, de Morree A, Travaglini KJ, Zhao J, Wang G, Hasegawa K, Sin H, Sit R, Okamoto J, Sinha R, Zhang Y, Karanewsky CJ, Pendleton JL, Morri M, Perret M, Aujard F, Stryer L, Artandi S, Fuller MT, Weissman IL, Rando TA, Ferrell JE Jr, Wang B, De Vlaminck I, Yang C, Casey KM, Albertelli MA, Pisco AO, Karkanias J, Neff N, Wu AR, Quake SR, Krasnow MA. A molecular cell atlas of mouse lemur, an emerging model primate. Nature. 2025 Aug;644(8075):173-184. doi: 10.1038/s41586-025-09113-9. Epub 2025 Jul 30. PMID: 40739356; PMCID: PMC12328211.
Ezran C, Liu S, Chang S, Ming J, Guethlein LA, Wang MFZ, Dehghannasiri R, Olivieri J, Frank HK, Tarashansky A, Koh W, Jing Q, Botvinnik O, Antony J; Tabula Microcebus Consortium; Pisco AO, Karkanias J, Yang C, Ferrell JE Jr, Boyd SD, Parham P, Long JZ, Wang B, Salzman J, De Vlaminck I, Wu AR, Quake SR, Krasnow MA. Mouse lemur cell atlas informs primate genes, physiology and disease. Nature. 2025 Aug;644(8075):185-196. doi: 10.1038/s41586-025-09114-8. Epub 2025 Jul 30. PMID: 40739355; PMCID: PMC12328237.
Stephanou A, Mantri M, Shankaranarayanan D, Li C, Lagman M, Xiang J, Pan C, Sun Y, Muthukumar T, Machaca K, De Vlaminck I, Suthanthiran M. Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers. bioRxiv [Preprint]. 2025 May 1:2025.04.28.651042. doi: 10.1101/2025.04.28.651042. PMID: 40654653; PMCID: PMC12247835.
Loy C, Agun G, Cheng MP, Gonzalez-Bocco IH, Lenz J, Belcher E, Bliss A, Eweis-LaBolle D, Chu T, Pidala J, Ritz J, De Vlaminck I. Plasma Cell-Free RNA Captures Immune Dynamics and Predicts GVHD after Hematopoietic Stem Cell Transplantation. medRxiv [Preprint]. 2025 Apr 17:2024.05.15.24307448. doi: 10.1101/2024.05.15.24307448. PMID: 38798589; PMCID: PMC11118637.

Whitman MA, Mantri M, Spanos E, Estroff LA, De Vlaminck I, Fischbach C. Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity. Biomaterials. 2025 Apr;315:122916. doi: 10.1016/j.biomaterials.2024.122916. Epub 2024 Oct 24. PMID: 39490060; PMCID: PMC11658005.
Pang Y, Prieto T, Gonzalez-Pena V, Aragon A, Xia Y, Kao S, Rajagopalan S, Zinno J, Quentin J, Laval J, Yuan D, Omans N, Klein D, MacKay M, De Vlaminck I, Easton J, Evans W, Landau DA, Gawad C. Measuring Longitudinal Genome-wide Clonal Evolution of Pediatric Acute Lymphoblastic Leukemia at Single-Cell Resolution. bioRxiv [Preprint]. 2025 Mar 19:2025.03.19.644196. doi: 10.1101/2025.03.19.644196. PMID: 40166290; PMCID: PMC11957134.
Holdener C, De Vlaminck I. Smoothie: Efficient Inference of Spatial Co-expression Networks from Denoised Spatial Transcriptomics Data. bioRxiv [Preprint]. 2025 Mar 2:2025.02.26.640406. doi: 10.1101/2025.02.26.640406. PMID: 40060619; PMCID: PMC11888426.
Jiang S, Mantri M, Maymi V, Leddon SA, Schweitzer P, Bhandari S, Holdener C, Ntekas I, Vollmers C, Flyak AI, Fowell DJ, Rudd BD, De Vlaminck I. A Temporal and Spatial Atlas of Adaptive Immune Responses in the Lymph Node Following Viral Infection. bioRxiv [Preprint]. 2025 Feb 6:2025.01.31.635509. doi: 10.1101/2025.01.31.635509. PMID: 39975238; PMCID: PMC11838507.

2024

Walter LD, Orton JL, Ntekas I, Fong EHH, Maymi VI, Rudd BD, De Vlaminck I, Elisseeff JH, Cosgrove BD. Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states. Nat Aging. 2024 Dec;4(12):1862-1881. doi: 10.1038/s43587-024-00756-3. Epub 2024 Nov 22. PMID: 39578558; PMCID: PMC11645289.
Whitman MA, Mantri M, Spanos E, Estroff LA, De Vlaminck I, Fischbach C. Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity. Biomaterials. 2024 Oct 24;315:122916. doi: 10.1016/j.biomaterials.2024.122916. Epub ahead of print. PMID: 39490060.
Shankaranarayanan D, Mantri M, Lagman M, Li C, Sharma VK, Muthukumar T, Xiang JZ, De Vlaminck I, Machaca K, Suthanthiran M. Blockade of store-operated calcium entry by BTP2 preserves anti-inflammatory gene expression in human peripheral blood mononuclear cells. Hum Immunol. 2024 Sep 26;85(6):111144. doi: 10.1016/j.humimm.2024.111144. Epub ahead of print. PMID: 39332042.
Loy CJ, Servellita V, Sotomayor-Gonzalez A, Bliss A, Lenz JS, Belcher E, Suslovic W, Nguyen J, Williams ME, Oseguera M, Gardiner MA; P.E.M.K.D.R.G.; C.H.A.R.M.S. the Study Group; Choi JH, Hsiao HM, Wang H, Kim J, Shimizu C, Tremoulet AH, Delaney M, DeBiasi RL, Rostad CA, Burns JC, Chiu CY, De Vlaminck I. Plasma cell-free RNA signatures of inflammatory syndromes in children. Proc Natl Acad Sci U S A. 2024 Sep 10;121(37):e2403897121. doi: 10.1073/pnas.2403897121. Epub 2024 Sep 6. PMID: 39240972; PMCID: PMC11406294.
Grodner B, Shi H, Farchione O, Vill AC, Ntekas I, Diebold PJ, Wu DT, Chen CY, Kim DM, Zipfel WR, Brito IL, De Vlaminck I. Spatial mapping of mobile genetic elements and their bacterial hosts in complex microbiomes. Nat Microbiol. 2024 Sep;9(9):2262-2277. doi: 10.1038/s41564-024-01735-5. Epub 2024 Jun 25. PMID: 38918467; PMCID: PMC11371653.
Ntekas I, De Vlaminck I. Spatial methods for microbiome-host interactions. Nat Biotechnol. 2024 Sep;42(9):1359-1360. doi: 10.1038/s41587-023-01996-1. PMID: 37985877.
Overbey EG, Kim J, Tierney BT, Park J, Houerbi N, Lucaci AG, Garcia Medina S, Damle N, Najjar D, Grigorev K, Afshin EE, Ryon KA, Sienkiewicz K, Patras L, Klotz R, Ortiz V, MacKay M, Schweickart A, Chin CR, Sierra MA, Valenzuela MF, Dantas E, Nelson TM, Cekanaviciute E, Deards G, Foox J, Narayanan SA, Schmidt CM, Schmidt MA, Schmidt JC, Mullane S, Tigchelaar SS, Levitte S, Westover C, Bhattacharya C, Lucotti S, Wain Hirschberg J, Proszynski J, Burke M, Kleinman AS, Butler DJ, Loy C, Mzava O, Lenz J, Paul D, Mozsary C, Sanders LM, Taylor LE, Patel CO, Khan SA, Suhail Mohamad M, Byhaqui SGA, Aslam B, Gajadhar AS, Williamson L, Tandel P, Yang Q, Chu J, Benz RW, Siddiqui A, Hornburg D, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Scott RT, Gilbert RR, Lai Polo SH, Altomare A, Kruglyak S, Levy S, Ariyapala I, Beer J, Zhang B, Hudson BM, Rininger A, Church SE, Beheshti A, Church GM, Smith SM, Crucian BE, Zwart SR, Matei I, Lyden DC, Garrett-Bakelman F, Krumsiek J, Chen Q, Miller D, Shuga J, Williams S, Nemec C, Trudel G, Pelchat M, Laneuville O, De Vlaminck I, Gross S, Bolton KL, Bailey SM, Granstein R, Furman D, Melnick AM, Costes SV, Shirah B, Yu M, Menon AS, Mateus J, Meydan C, Mason CE. The Space Omics and Medical Atlas (SOMA) and international astronaut biobank. Nature. 2024 Aug;632(8027):1145-1154. doi: 10.1038/s41586-024-07639-y. Epub 2024 Jun 11. PMID: 38862028; PMCID: PMC11357981.
Mason CE, Green J, Adamopoulos KI, Afshin EE, Baechle JJ, Basner M, Bailey SM, Bielski L, Borg J, Borg J, Broddrick JT, Burke M, Caicedo A, Castañeda V, Chatterjee S, Chin CR, Church G, Costes SV, De Vlaminck I, Desai RI, Dhir R, Diaz JE, Etlin SM, Feinstein Z, Furman D, Garcia-Medina JS, Garrett-Bakelman F, Giacomello S, Gupta A, Hassanin A, Houerbi N, Irby I, Javorsky E, Jirak P, Jones CW, Kamal KY, Kangas BD, Karouia F, Kim J, Kim JH, Kleinman AS, Lam T, Lawler JM, Lee JA, Limoli CL, Lucaci A, MacKay M, McDonald JT, Melnick AM, Meydan C, Mieczkowski J, Muratani M, Najjar D, Othman MA, Overbey EG, Paar V, Park J, Paul AM, Perdyan A, Proszynski J, Reynolds RJ, Ronca AE, Rubins K, Ryon KA, Sanders LM, Glowe PS, Shevde Y, Schmidt MA, Scott RT, Shirah B, Sienkiewicz K, Sierra MA, Siew K, Theriot CA, Tierney BT, Venkateswaran K, Hirschberg JW, Walsh SB, Walter C, Winer DA, Yu M, Zea L, Mateus J, Beheshti A. A second space age spanning omics, platforms and medicine across orbits. Nature. 2024 Aug;632(8027):995-1008. doi: 10.1038/s41586-024-07586-8. Epub 2024 Jun 11. PMID: 38862027.
Loy C, Ahmann L, De Vlaminck I, Gu W. Liquid Biopsy Based on Cell-Free DNA and RNA. Annu Rev Biomed Eng. 2024 Jul;26(1):169-195. doi: 10.1146/annurev-bioeng-110222-111259. Epub 2024 Jun 20. PMID: 38346275.
Kim J, Tierney BT, Overbey EG, Dantas E, Fuentealba M, Park J, Narayanan SA, Wu F, Najjar D, Chin CR, Meydan C, Loy C, Mathyk B, Klotz R, Ortiz V, Nguyen K, Ryon KA, Damle N, Houerbi N, Patras LI, Schanzer N, Hutchinson GA, Foox J, Bhattacharya C, Mackay M, Afshin EE, Hirschberg JW, Kleinman AS, Schmidt JC, Schmidt CM, Schmidt MA, Beheshti A, Matei I, Lyden D, Mullane S, Asadi A, Lenz JS, Mzava O, Yu M, Ganesan S, De Vlaminck I, Melnick AM, Barisic D, Winer DA, Zwart SR, Crucian BE, Smith SM, Mateus J, Furman D, Mason CE. Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight. Nat Commun. 2024 Jun 11;15(1):4954. doi: 10.1038/s41467-024-49211-2. PMID: 38862516; PMCID: PMC11166952.
Borg J, Loy C, Kim J, Buhagiar A, Chin C, Damle N, De Vlaminck I, Felice A, Liu T, Matei I, Meydan C, Muratani M, Mzava O, Overbey E, Ryon KA, Smith SM, Tierney BT, Trudel G, Zwart SR, Beheshti A, Mason CE, Borg J. Spatiotemporal expression and control of haemoglobin in space. Nat Commun. 2024 Jun 11;15(1):4927. doi: 10.1038/s41467-024-49289-8. PMID: 38862545; PMCID: PMC11166948.
Chang A, Loy CJ, Eweis-LaBolle D, Lenz JS, Steadman A, Andgrama A, Nhung NV, Yu C, Worodria W, Denkinger CM, Nahid P, Cattamanchi A, De Vlaminck I. Circulating cell-free RNA in blood as a host response biomarker for detection of tuberculosis. Nat Commun. 2024 Jun 10;15(1):4949. doi: 10.1038/s41467-024-49245-6. PMID: 38858368; PMCID: PMC11164910.
Djomnang LK, Li C, Mzava O, Cheng AP, Chang A, Lenz JS, Suthanthiran M, Lee JR, Dadhania DM, De Vlaminck I. A quantitative comparison of urine centrifugation and filtration for the isolation and analysis of urinary nucleic acid biomarkers. Sci Rep. 2024 May 13;14(1):10872. doi: 10.1038/s41598-024-54239-x. PMID: 38740837; PMCID: PMC11091160.
Sanketi BD, Mantri M, Huang L, Tavallaei MA, Hu S, Wang MFZ, De Vlaminck I, Kurpios NA. Villus myofibroblasts are developmental and adult progenitors of mammalian gut lymphatic musculature. Dev Cell. 2024 May 6;59(9):1159-1174.e5. doi: 10.1016/j.devcel.2024.03.005. Epub 2024 Mar 26. PMID: 38537630; PMCID: PMC11078612.
Garcia-Medina JS, Sienkiewicz K, Narayanan SA, Overbey EG, Grigorev K, Ryon KA, Burke M, Proszynski J, Tierney B, Schmidt CM, Mencia-Trinchant N, Klotz R, Ortiz V, Foox J, Chin C, Najjar D, Matei I, Chan I, Cruchaga C, Kleinman A, Kim J, Lucaci A, Loy C, Mzava O, De Vlaminck I, Singaraju A, Taylor LE, Schmidt JC, Schmidt MA, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Altomare A, Kruglyak S, Levy S, Yu M, Hassane DC, Bailey SM, Bolton K, Mateus J, Mason CE. Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight. Precis Clin Med. 2024 Apr 8;7(1):pbae007. doi: 10.1093/pcmedi/pbae007. PMID: 38634106; PMCID: PMC11022651.
Liu S, Ezran C, Wang MFZ, Li Z, Awayan K; Tabula Microcebus Consortium; Long JZ, De Vlaminck I, Wang S, Epelbaum J, Kuo CS, Terrien J, Krasnow MA, Ferrell JE Jr. An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome. Nat Commun. 2024 Mar 11;15(1):2188. doi: 10.1038/s41467-024-46070-9. PMID: 38467625; PMCID: PMC10928088.
Mantri M, Zhang HH, Spanos E, Ren YA, De Vlaminck I. A spatiotemporal molecular atlas of the ovulating mouse ovary. Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2317418121. doi: 10.1073/pnas.2317418121. Epub 2024 Jan 22. PMID: 38252830; PMCID: PMC10835069.
Vill AC, Rice EJ, De Vlaminck I, Danko CG, Brito IL. Precision run-on sequencing (PRO-seq) for microbiome transcriptomics. Nat Microbiol. 2024 Jan;9(1):241-250. doi: 10.1038/s41564-023-01558-w. Epub 2024 Jan 3. PMID: 38172625; PMCID: PMC11059318.

Diel de Amorim

2024

Cheong SH, Franklin-Guild R, Goodman LB, Lago-Alvarez Y, Lee YL, de Aguiar LH, de Amorim MD, Altier C. Detection of fungal and bacterial organisms from clinical uterine samples of horses using Next-Generation Sequencing in comparison with culture. J Equine Vet Sci. 2024 Nov 9:105214. doi: 10.1016/j.jevs.2024.105214. Epub ahead of print. PMID: 39527989.
Byron M, Lection J, Foster RA, Chenier T, Wagner B, Diel de Amorim M. Prostaglandin-related genes are differentially expressed in equine endometrium with different biopsy grade, degrees of inflammation, and fibrosis. Theriogenology. 2024 Oct 1;227:151-156. doi: 10.1016/j.theriogenology.2024.07.014. Epub 2024 Jul 19. PMID: 39089078.
Lection J, Wagner B, Byron M, Miller A, Rollins A, Chenier T, Cheong SH, Diel de Amorim M. Inflammatory markers for differentiation of endometritis in the mare. Equine Vet J. 2024 Jul;56(4):678-687. doi: 10.1111/evj.14058. Epub 2024 Jan 14. PMID: 38219734.
Bernard M, Donnelly CG, Miller A, Diel de Amorim M. Diagnosis and management of placentitis with severe funisitis in a multiparous Warmblood mare. J Equine Vet Sci. 2024 Jun;137:105075. doi: 10.1016/j.jevs.2024.105075. Epub 2024 May 1. PMID: 38697371.

Donnelly

2026

Burdette TN, Delvescovo B, Wise Bellin E, Divers TJ, Donnelly CG. Ursodeoxycholic Acid Oral Pharmacokinetics and Plasma Bile Acid Profile Changes in a Population of Healthy Neonatal Foals. J Vet Pharmacol Ther. 2026 Sep 28. doi: 10.1111/jvp.70111. Epub ahead of print. PMID: 42803749.
Louie EW, Macias AA, Mitchell KJ, Divers TJ, Donnelly CG. Cardiovascular phenotype analysis in large and abnormal offspring calves in relation to assisted reproductive technology†. Biol Reprod. 2026 Aug 18;115(2):361-368. doi: 10.1093/biolre/ioaf223. PMID: 41074770; PMCID: PMC13293166.
Macias A, Delvescovo B, Donaldson SF, Divers TJ, Donnelly CG. Pharmacokinetics of Intragastric Ursodeoxycholic Acid and Its Impact on Bile Acid Profiles in Horses. J Vet Pharmacol Ther. 2026 May;49(3):282-288. doi: 10.1111/jvp.70048. Epub 2026 Jan 26. PMID: 41588271.
Maas LT, Louie EW, Finno CJ, Donnelly CG, Stern JA, Hill AE, Morgan JM. Cardiac arrhythmia prevalence and risk factors in 24-h electrocardiograms of sedentary horses. Equine Vet J. 2026 May;58(3):718-727. doi: 10.1111/evj.14543. Epub 2025 Jul 18. PMID: 40679167; PMCID: PMC13041602.

2025

Donnelly CG, Peng S, Pflieger L, Manfredi J, Coleman M, Rappaport N, Price ND, Finno CJ. Bile acids segregate metabolic syndrome in a cohort of 100 deeply phenotyped horses. Commun Biol. 2025 Nov 27;8(1):1711. doi: 10.1038/s42003-025-09111-7. PMID: 41310118; PMCID: PMC12660777.
Louie EW, Macias AA, Mitchell KJ, Divers TJ, Donnelly CG. Cardiovascular phenotype analysis in large and abnormal offspring calves in relation to assisted reproductive technology†. Biol Reprod. 2025 Oct 11:ioaf223. doi: 10.1093/biolre/ioaf223. Epub ahead of print. PMID: 41074770.
Bacon EK, Finno CJ, Donnelly CG, Haase B, Knych HK, Velie BD. Evaluating the extent to which ataxia and responsiveness to stimuli reflect the efficacy of xylazine sedation using pharmacokinetics. J Equine Vet Sci. 2025 Sep;152:105652. doi: 10.1016/j.jevs.2025.105652. Epub 2025 Jul 9. PMID: 40645303.
Bacon EK, Donnelly CG, Finno CJ, Haase B, Velie BD. Exploring the genetic influences on equine analgesic efficacy through genome-wide association analysis of ranked pain responses. Vet J. 2025 Aug;312:106347. doi: 10.1016/j.tvjl.2025.106347. Epub 2025 Apr 10. PMID: 40216012.
Finno CJ, Rogers SL, Donnelly CG, Affolter VK, Woolard K, Miller AD, Bellone RR, Petersen JL. Spatial transcriptomics defines the cell-specific RNA landscape of equine dorsal root ganglia. Vet Pathol. 2025 Jul;62(4):546-554. doi: 10.1177/03009858241312623. Epub 2025 Feb 6. PMID: 39916473; PMCID: PMC12185904.

2024

Bernard ME, Coffin HR, Taylor RP, Donnelly CG. Craniofacial malformations in a stillborn mixed-breed dog as a cause for dystocia. Vet Med Sci. 2024 Sep;10(5):e70010. doi: 10.1002/vms3.70010. PMID: 39258534; PMCID: PMC11388054.
Bacon EK, Donnelly CG, Bellone RR, Haase B, Finno CJ, Velie BD. Preliminary investigation of potential links between pigmentation variants and opioid analgesic effectiveness in horses during cerebrospinal fluid centesis. BMC Vet Res. 2024 Jul 12;20(1):311. doi: 10.1186/s12917-024-04139-z. PMID: 38997753; PMCID: PMC11245827.
Bernard M, Donnelly CG, Miller A, Diel de Amorim M. Diagnosis and management of placentitis with severe funisitis in a multiparous Warmblood mare. J Equine Vet Sci. 2024 Jun;137:105075. doi: 10.1016/j.jevs.2024.105075. Epub 2024 May 1. PMID: 38697371.
Willis AT, Dahlgren AR, Woolard KD, Ghosh S, Donnelly CG, de la Concha-Bermejillo A, Pacheco A, Watson KD, Berryhill E, Aleman M, Wensley F, Humphreys S, Whitehead AE, Goldsmith D, Chesen B, Ragsdale J, Tompkins JE, Nash R, Plunkett AH, Qualls HJ, Rodriguez K, Hochanadel D, Miller AD, Finno CJ. Clinicopathological and pedigree investigation of a novel spinocerebellar neurological disease in juvenile Quarter Horses in North America. J Vet Intern Med. 2024 May-Jun;38(3):1808-1814. doi: 10.1111/jvim.17049. Epub 2024 Apr 26. PMID: 38669583; PMCID: PMC11099776.
Powers A, Peek SF, Reed S, Donnelly CG, Tinkler S, Gasper D, Woolard KD, Finno CJ. Equine neuroaxonal dystrophy/degenerative myeloencephalopathy in Gypsy Vanner horses. J Vet Intern Med. 2024 May-Jun;38(3):1792-1798. doi: 10.1111/jvim.17062. Epub 2024 Apr 13. PMID: 38613444; PMCID: PMC11099697.
Esdaile E, Knickelbein KE, Donnelly CG, Ferneding M, Motta MJ, Story BD, Avila F, Finno CJ, Gilger BC, Sandmeyer L, Thomasy S, Bellone RR. Additional evidence supports GRM6 p.Thr178Met as a cause of congenital stationary night blindness in three horse breeds. Vet Ophthalmol. 2024 May;27(3):248-255. doi: 10.1111/vop.13151. Epub 2023 Oct 10. PMID: 37815029; PMCID: PMC13267762.
Ma Y, Peng S, Donnelly CG, Ghosh S, Miller AD, Woolard K, Finno CJ. Genetic polymorphisms in vitamin E transport genes as determinants for risk of equine neuroaxonal dystrophy. J Vet Intern Med. 2024 Jan-Feb;38(1):417-423. doi: 10.1111/jvim.16924. Epub 2023 Nov 8. PMID: 37937700; PMCID: PMC10800183.
Lightbody KL, Austin A, Lambert PA, von Samson-Himmelstjerna G, Jürgenschellert L, Krücken J, Nielsen MK, Sallé G, Reigner F, Donnelly CG, Finno CJ, Walshe N, Mulcahy G, Housby-Skeggs N, Grice S, Geyer KK, Austin CJ, Matthews JB. Validation of a serum ELISA test for cyathostomin infection in equines. Int J Parasitol. 2024 Jan;54(1):23-32. doi: 10.1016/j.ijpara.2023.07.001. Epub 2023 Aug 1. PMID: 37536388.

Duan

2026

Bynum JC, Biga PR, Grytz R; IISAGE Consortium; Riddle NC. Lifespan and reproductive aging in captive Northern tree shrews (Tupaia belangeri). Geroscience. 2026 Oct 31. doi: 10.1007/s11357-026-02623-y. Epub ahead of print. PMID: 42963494.
Yu X, Shambhvi, Ceballos DA, Ferreira MM, Zapata A, Seneviratne N, Pokharel S, Fang Y, Li G, Leal Yepes FA, McFadden JW, Duan JE. Single-nucleus RNA sequencing reveals cell type-specific responses to heat stress in bovine mammary gland. J Anim Sci Biotechnol. 2026 Jul 16;17(1):148. doi: 10.1186/s40104-026-01468-x. PMID: 42464414; PMCID: PMC13374132.
Abdelhady A, Zhang J, Wu CK, Lee Lee Y, Shi M, Crane PL, Diel de Amorim M, Porter IR, Zheng Q, Thorne RE, Duan JE, Cheong SH. Ice-free vitrification of embryos and its impact on post-warming outcomes. Sci Rep. 2026 May 15;16(1):24465. doi: 10.1038/s41598-026-46755-9. PMID: 42141048; PMCID: PMC13451337.
Su Y, Zhao R, Fang Y, Renxiu M, Li G, Jin L, Liu J, Yang Z, Li N, Zhu J, Mishra N, Kaback D, Yee SP, Luo Y, Wan W, Zhao Y, Wang X, Han S, Xiao P, Lei C, Duan JE, Tang Y, Tian XC. Bovine formative embryonic stem cell plasticity in embryonic and extraembryonic differentiation. Stem Cells. 2026 Jan 8;44(1):sxaf068. doi: 10.1093/stmcls/sxaf068. PMID: 41129285.

2025

Fang Y, Su Y, Meisel R, Walters JR, Gamble T, Randolph EC, Yu X, Shi M, Li G, Zhang J; IISAGE Consortium; Tian XC, Tang Y, Duan JE. Comparative transcriptomic analysis of embryonic stem cells across mammalian species. iScience. 2025 Dec 24;29(1):114542. doi: 10.1016/j.isci.2025.114542. PMID: 41583562; PMCID: PMC12828385.
Su Y, Zhao R, Fang Y, Renxiu M, Li G, Jin L, Liu J, Yang Z, Li N, Zhu J, Mishra N, Kaback D, Yee SP, Luo Y, Wan W, Zhao Y, Wang X, Han S, Xiao P, Lei C, Duan JE, Tang Y, Tian XC. Bovine Formative Embryonic Stem Cell Plasticity in Embryonic and Extraembryonic Differentiation. Stem Cells. 2025 Oct 23:sxaf068. doi: 10.1093/stmcls/sxaf068. Epub ahead of print. PMID: 41129285.
Shi M, Li G, Araujo HM, Lee AS, Zhang J, Lee YL; IISAGE Consortium; Cheong SH, Duan JE. Sex-biased transcriptome in in vitro produced bovine early embryos. Cell Biosci. 2025 Aug 27;15(1):123. doi: 10.1186/s13578-025-01459-x. PMID: 40866999; PMCID: PMC12392601.
Yu X, Harman RM, Danev N, Li G, Fang Y, Van de Walle GR, Duan JE. Heat stress and recovery induce transcriptomic changes in lactogenic-like bovine mammary epithelial (MAC-T) cells. Physiol Genomics. 2025 Sep 1;57(9):551-565. doi: 10.1152/physiolgenomics.00127.2024. Epub 2025 Jul 18. PMID: 40679625.
Biga PR, Duan JE, Young TE, Marks JR, Bronikowski A, Decena LP, Randolph EC, Pavuluri AG, Li G, Fang Y, Wilkinson GS, Singh G, Nigrin NT, Larschan EN, Lonski AJ, Riddle NC; IISAGE Consortium. Hallmarks of aging: A user’s guide for comparative biologists. Ageing Res Rev. 2025 Feb;104:102616. doi: 10.1016/j.arr.2024.102616. Epub 2024 Dec 4. PMID: 39643212.

2024

Danev N, Li G, Duan JE, Van de Walle GR. Comparative transcriptomic analysis of bovine mesenchymal stromal cells reveals tissue-source and species-specific differences. iScience. 2024 Jan 12;27(2):108886. doi: 10.1016/j.isci.2024.108886. PMID: 38318381; PMCID: PMC10838956.

Fejes Tóth

See Dr. Fejes Tóth’s Member Profile for more information on her publication history.

Finkelstein

2026

Massara P, Kirkland J, Pagani I, Huey SL, Hirsh H, McDonald D, Patel L, Finkelstein JL, Gantz M, Wang F, Erickson D, Wells MT, Elemento O, Knight R, Mehta S. Author Correction: Applying Artificial Intelligence and machine learning in precision nutrition. Nat Commun. 2026 Oct 28;17(1):11201. doi: 10.1038/s41467-026-77960-9. Erratum for: Nat Commun. 2026 Jul 6;17(1):5880. doi: 10.1038/s41467-026-75004-w. PMID: 42957710; PMCID: PMC13720029.
Srinivasan B, Finkelstein JL, Erickson D, Mehta S. Europium nanoparticle-based lateral flow assay for rapid detection of herpes simplex virus 2-specific antibodies in serum: a preliminary evaluation. RSC Adv. 2026 Oct 9;16(47):62036-62045. doi: 10.1039/d6ra04688f. PMID: 42857699; PMCID: PMC13651804.
Mehta S, Huey SL, Massara P, Liu L, Whisner CM, Deng Y, Novotny R, Antwi J, Kim S, Musaad S, Erickson D, Estrin D, Finkelstein JL, Joachims T, Kagemann CH, Tamimi R, Thomas D, Wells MT. Training Perspectives from the NIH T32 Artificial Intelligence for Precision Nutrition Programs. J Nutr. 2026 Oct;156(10):101796. doi: 10.1016/j.tjnut.2026.101796. Epub 2026 Aug 22. PMID: 42632616; PMCID: PMC13693270.
Guéant JL, Alpers DH, Allen LH, Andres E, Devlin AM, Green A, Green R, Guéant Rodriguez RM, Hannibal L, Harrington D, Mason JB, McCaddon A, Miller JW, Murphy M, Nexo E, McNulty H, Owen PJ, Quadros E, Rosenblatt D, Refsum H, Rietsema W, Stabler S, Ward M, Yajnik C, Finkelstein JL. Expert Perspectives on Diagnosis and Management of Vitamin B12 Deficiency in Adults. Adv Nutr. 2026 Oct;17(10):100726. doi: 10.1016/j.advnut.2026.100726. Epub 2026 Aug 25. PMID: 42641763; PMCID: PMC13653423.
Huey SL, Cole NL, Pagani I, González A, Finkelstein JL, Haas JD, Udipi SA, Ghugre P, Potdar RD, Knight R, Mehta S. Effect of a complementary feeding intervention based on iron- and zinc-biofortified pearl millet on the gut microbiota in 12-18-month-old children: a randomized trial. Nat Commun. 2026 Jul 30;17(1):9242. doi: 10.1038/s41467-026-75674-6. PMID: 42669658; PMCID: PMC13527057.
Massara P, Kirkland J, Pagani I, Huey SL, Hirsh H, McDonald D, Patel L, Finkelstein JL, Gantz M, Wang F, Erickson D, Wells MT, Elemento O, Knight R, Mehta S. Applying Artificial Intelligence and machine learning in precision nutrition. Nat Commun. 2026 Jul 6;17(1):5880. doi: 10.1038/s41467-026-75004-w. Erratum in: Nat Commun. 2026 Oct 28;17(1):11201. doi: 10.1038/s41467-026-77960-9. PMID: 42409828; PMCID: PMC13338271.
Larvie DY, Güitrón Leal CE, Venkatramanan S, Palma Molina XE, Steel LB, Kuriyan R, Finkelstein JL. Vitamin B12 supplementation for growth, development, and cognition in children. Cochrane Database Syst Rev. 2026 Jun 2;6(6):CD015264. doi: 10.1002/14651858.CD015264.pub2. PMID: 42227307; PMCID: PMC13227581.
Sley EG, Fothergill A, Steel LB, Larvie DY, Roy Choudhury D, Weeks J, Finkelstein JL. Vitamin B12 supplementation for anaemia, vitamin B12 status, and health outcomes in women of reproductive age. Cochrane Database Syst Rev. 2026 May 8;5(5):CD016233. doi: 10.1002/14651858.CD016233. PMID: 42100907; PMCID: PMC13154363.
Fahim SM, Miah M, Marcotte M, Zoria N, Ahmed M, Huey SL, Erickson D, Finkelstein JL, Mehta S. Saliva as a Matrix for Primary Care: Feasibility and Scoping of Its Use for Assessment of Nutrition and Inflammation. Adv Nutr. 2026 May;17(5):100625. doi: 10.1016/j.advnut.2026.100625. Epub 2026 Apr 1. PMID: 41933704; PMCID: PMC13112399.
Mehta S, Huey SL, Ghugre PS, Potdar RD, Venkatramanan S, Krisher JT, Ruth CJ, Chopra HV, Thorat A, Thakker V, Johnson L, Powis L, Raveendran Y, Rajagopalan K, Haas JD, Finkelstein JL, Udipi SA; Project Sabal. A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12-18 months living in urban slums. Clin Nutr. 2026 Apr;59:106517. doi: 10.1016/j.clnu.2025.11.002. Epub 2026 Feb 9. PMID: 41740296.
Mehta S, Huey SL, Ghugre PS, Potdar RD, Venkatramanan S, Krisher JT, Ruth CJ, Chopra HV, Thorat A, Thakker V, Johnson L, Powis L, Raveendran Y, Haas JD, Finkelstein JL, Udipi SA; Project Sabal. Retraction notice to “A randomized trial of iron- and zinc-biofortified pearl millet-based complementary feeding in children aged 12 to 18 months living in urban slums” [Clin Nutr 41 (2022) 937-947]. Clin Nutr. 2026 Mar;58:106578. doi: 10.1016/j.clnu.2026.106578. Epub 2026 Jan 21. PMID: 41571510.
Qi YP, Crider KS, Gutman J, Centeno-Tablante E, Fothergill A, Daniels K, Yeung LF, Mai CT, Mehta S, Williams JL, Finkelstein JL. Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas. Cochrane Database Syst Rev. 2026 Feb 18;2(2):CD014217. doi: 10.1002/14651858.CD014217.pub2. PMID: 41705996; PMCID: PMC12915520.

2025

Srinivasan B, Rivera M, Caicedo C, Cárdenas WB, Finkelstein JL, Erickson D, Mehta S. Comparison of two nanomaterial labels for detection of SARS-CoV-2 nucleocapsid antigen to improve analytical performance of lateral flow immunoassays. RSC Adv. 2025 Dec 19;15(59):51162-51170. doi: 10.1039/d5ra08197a. PMID: 41426057; PMCID: PMC12716254.
Guetterman HM, Crider KS, Fothergill A, Bose B, Johnson CB, Jabbar S, Zhang M, Pfeiffer CM, Rose CE, Qi YP, Williams JL, Mehta S, Kuriyan R, Finkelstein JL. Vitamin B12 status and metabolic health in women of reproductive age: Population-based biomarker survey. Clin Nutr ESPEN. 2025 Aug;68:176-188. doi: 10.1016/j.clnesp.2025.05.011. Epub 2025 May 9. PMID: 40349845; PMCID: PMC12256199.
Mehta S, Huey SL, Fahim SM, Sinha S, Rajagopalan K, Ahmed T, Knight R, Finkelstein JL. Advances in artificial intelligence and precision nutrition approaches to improve maternal and child health in low resource settings. Nat Commun. 2025 Aug 18;16(1):7673. doi: 10.1038/s41467-025-62985-3. PMID: 40825980; PMCID: PMC12361493.
Fahim SM, Huey SL, Palma Molina XE, Agarwal N, Ridwan P, Ji N, Kibbee M, Kuriyan R, Finkelstein JL, Mehta S. Gut microbiome-based interventions for the management of obesity in children and adolescents aged up to 19 years. Cochrane Database Syst Rev. 2025 Jul 10;7(7):CD015875. doi: 10.1002/14651858.CD015875. PMID: 40637175; PMCID: PMC12243456.
Sinha S, Huey SL, Shukla AP, Kuriyan R, Finkelstein JL, Mehta S. Connecting precision nutrition with the Food is Medicine approach. Trends Endocrinol Metab. 2025 Jun;36(6):511-520. doi: 10.1016/j.tem.2024.08.012. Epub 2024 Sep 27. PMID: 39341732.
Sinha P, Bhargava M, Carwile ME, Dauphinais MR, Tisile P, Cintron C, Locks LM, Hauser J, Oliver M, Heysell SK, Mehta S, Finkelstein JL, Koura KG, Cegielski JP, Houben RMGJ, McQuaid CF, Bhargava A. A roadmap for integrating nutritional assessment, counselling, and support into the care of people with tuberculosis. Lancet Glob Health. 2025 May;13(5):e967-e973. doi: 10.1016/S2214-109X(25)00021-X. Epub 2025 Mar 19. PMID: 40120593; PMCID: PMC12276968.
Sinha S, Hackl LS, Huey SL, Lambertini E, Nordhagen S, Bennett AM, Shrestha N, Cole NL, Finkelstein JL, Mehta S. Overview of foodborne hazards associated with inflammation and metabolic health. BMC Glob Public Health. 2025 Apr 8;3(1):31. doi:
Locks LM, Parekh A, Newell K, Dauphinais MR, Cintron C, Maloomian K, Yu EA, Finkelstein JL, Mehta S, Sinha P. The ABCDs of Nutritional Assessment in Infectious Diseases Research. J Infect Dis. 2025 Mar 17;231(3):562-572. doi: 10.1093/infdis/jiae540. PMID: 39504432; PMCID: PMC11911783. 10.1186/s44263-025-00150-0. PMID: 40200316; PMCID: PMC11980346.
Guetterman HM, Rajagopalan K, Fox AM, Johnson CB, Fothergill A, George N, Krisher JT, Haas JD, Mehta S, Williams JL, Crider KS, Finkelstein JL. A Randomized Crossover Trial of Acceptability of Quadruple-Fortified Salt in Women and their Households in Southern India. J Nutr. 2025 Jan;155(1):322-337. doi: 10.1016/j.tjnut.2024.10.037. Epub 2024 Oct 26. PMID: 39490799; PMCID: PMC11795687.
Huey SL, Mehta NH, Steinhouse RS, Jin Y, Kibbee M, Kuriyan R, Finkelstein JL, Mehta S. Precision nutrition-based interventions for the management of obesity in children and adolescents up to the age of 19 years. Cochrane Database Syst Rev. 2025 Jan 30;1(1):CD015877. doi: 10.1002/14651858.CD015877. PMID: 39882755; PMCID: PMC12045580.

2024

Ji N, Kumar A, Joe W, Kuriyan R, Sethi V, Finkelstein JL, Mehta S. Prevalence and Correlates of Double and Triple Burden of Malnutrition Among Children and Adolescents in India: The Comprehensive National Nutrition Survey. J Nutr. 2024 Oct;154(10):2932-2947. doi: 10.1016/j.tjnut.2024.08.021. Epub 2024 Aug 28. PMID: 39209112.
Finkelstein JL, Cuthbert A, Weeks J, Venkatramanan S, Larvie DY, De-Regil LM, Garcia-Casal MN. Daily oral iron supplementation during pregnancy. Cochrane Database Syst Rev. 2024 Aug 15;8(8):CD004736. doi: 10.1002/14651858.CD004736.pub6. PMID: 39145520; PMCID: PMC11325660.
Mehta NH, Huey SL, Kuriyan R, Peña-Rosas JP, Finkelstein JL, Kashyap S, Mehta S. Potential Mechanisms of Precision Nutrition-Based Interventions for Managing Obesity. Adv Nutr. 2024 Mar;15(3):100186. doi: 10.1016/j.advnut.2024.100186. Epub 2024 Feb 3. PMID: 38316343; PMCID: PMC10914563.
Finkelstein JL, Fothergill A, Venkatramanan S, Layden AJ, Williams JL, Crider KS, Qi YP. Vitamin B12 supplementation during pregnancy for maternal and child health outcomes. Cochrane Database Syst Rev. 2024 Jan 8;1(1):CD013823. doi: 10.1002/14651858.CD013823.pub2. PMID: 38189492; PMCID: PMC10772977.
Dauphinais MR, Koura KG, Narasimhan PB, Mehta S, Finkelstein JL, Heysell SK, Sinha P. Nutritionally acquired immunodeficiency must be addressed with the same urgency as HIV to end tuberculosis. BMC Glob Public Health. 2024 Jan 12;2(1):4. doi: 10.1186/s44263-023-00035-0. PMID: 39681926; PMCID: PMC11622872.

Fischbach-Teschl

2026

Ling L, Crowley JC, Tan ML, Kunitake JAMR, Shimpi AA, Williams RM, Estroff LA, Fischbach C, Zipfel WR. Assessing cellular metabolic dynamics with two-photon NAD(P)H fluorescence polarization microscopy. Sci Adv. 2026 Sep 4;12(36):eaed6844. doi: 10.1126/sciadv.aed6844. Epub 2026 Sep 4. PMID: 42696582; PMCID: PMC13544203.
Knode BK, Beeghly GF, Schutrum BE, Wang D, Zheng Y, Battistella A, Goswami R, Eom CY, Kopyeva I, Bozec A, Guck J, Nishimura N, Girardo S, O’Hern CS, Fischbach C. Adipose-mimetic granular hydrogels uncover biophysical cues driving breast cancer invasion. Cell Biomater. 2026 Aug 18;2(8):100411. doi: 10.1016/j.celbio.2026.100411. Epub 2026 Mar 3. PMID: 42746462; PMCID: PMC13577451.
Schutrum BE, Deng J, Kim JH, Gao A, Hur E, Crowley JC, Ling L, Pirtz MG, Ralston CQ, Nikitin AY, Fischbach C. Shape factor analysis as a quantitative framework for assessing spheroid and organoid morphology and invasiveness. APL Bioeng. 2026 Jul 1;10(3):036101. doi: 10.1063/5.0333152. PMID: 42389052; PMCID: PMC13322776.
Karimu SO, Sutter SM, Choi S, Sun S, Butcher J, Estroff LA, Fischbach C. Directional bone matrix mineralization in the CAM assay is governed by vascular integration and matrix remodeling. bioRxiv [Preprint]. 2026 Jun 2:2026.05.29.728599. doi: 10.64898/2026.05.29.728599. PMID: 42282631; PMCID: PMC13251954.
Sempertegui N, Yan Y, Whitman MA, Beeghly GF, Choi S, Miller A, Estroff LA, Fischbach C. Mineralized bone matrix attenuates breast cancer cell malignancy by altering MSC mechanoregulation. Biomaterials. 2026 Apr;327:123763. doi: 10.1016/j.biomaterials.2025.123763. Epub 2025 Oct 4. PMID: 41061608.
Beeghly GF, Kopyeva I, Deng J, Pincus MI, Varshney RR, Giri DD, Falcone DJ, Rudolph MC, Antonyak MA, Iyengar NM, Fischbach C. Large adipocytes increase vesicle-mediated lipid release and promote breast cancer malignancy. Cell Rep. 2026 Mar 24;45(3):117061. doi: 10.1016/j.celrep.2026.117061. Epub 2026 Mar 5. PMID: 41790552; PMCID: PMC13339303.
Beeghly GF, Deng J, Fischbach C. Protocol to fabricate elastomer microwells for three-dimensional culture of primary adipocytes. STAR Protoc. 2026 Mar 20;7(1):104437. doi: 10.1016/j.xpro.2026.104437. Epub 2026 Mar 4. Erratum for: STAR Protoc. 2024 Sep 20;5(3):103264. doi: 10.1016/j.xpro.2024.103264. PMID: 41785083; PMCID: PMC12970393.
Schutrum BE, Deng J, Kim JH, Gao A, Hur E, Crowley JC, Ling L, Pirtz MG, Ralston CQ, Nikitin AY, Fischbach C. Shape Factor Analysis as a Quantitative Framework for Assessing Spheroid and Organoid Morphology and Invasiveness. bioRxiv [Preprint]. 2026 Mar 12:2026.03.10.710632. doi: 10.64898/2026.03.10.710632. Update in: APL Bioeng. 2026 Jul 01;10(3):036101. doi: 10.1063/5.0333152. PMID: 41959082; PMCID: PMC13060997.
Sievers-Liebschner J, Welzel PB, Fusenig M, Sturm L, Pette D, Wagermaier W, Fischbach C, Fratzl P, Werner C. Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro. Adv Sci (Weinh). 2026 Mar;13(18):e19798. doi: 10.1002/advs.202519798. Epub 2026 Jan 27. PMID: 41589653; PMCID: PMC13042468.
Persson KM, Whitman MA, Fischbach C. Engineered bone matrix models for understanding breast cancer skeletal metastasis. Cancer Metastasis Rev. 2026 Jan 24;45(1):4. doi: 10.1007/s10555-025-10310-1. PMID: 41579220; PMCID: PMC12831698.

2025

Knode BK, Beeghly GF, Schutrum BE, Wang D, Zheng Y, Battistella A, Goswami R, Eom CY, Bozec A, Guck J, Nishimura N, Girardo S, O’Hern CS, Fischbach C. Adipose-mimetic granular hydrogels uncover biophysical cues driving breast cancer invasion. bioRxiv [Preprint]. 2025 Oct 24:2025.10.23.684224. doi: 10.1101/2025.10.23.684224. PMID: 41278796; PMCID: PMC12633341.
Beeghly GF, Pincus MI, Varshney RR, Giri DD, Falcone DJ, Rudolph MC, Antonyak MA, Iyengar NM, Fischbach C. Large adipocytes alter mode of lipid release and promote breast cancer malignancy. bioRxiv [Preprint]. 2025 Sep 24:2025.03.28.645549. doi: 10.1101/2025.03.28.645549. Update in: Cell Rep. 2026 Mar 24;45(3):117061. doi: 10.1016/j.celrep.2026.117061. PMID: 40236195; PMCID: PMC11996363.
Ling L, Crowley JC, Tan ML, Kunitake JAMR, Shimpi AA, Williams RM, Estroff LA, Fischbach C, Zipfel WR. Assessing cellular metabolic dynamics with NAD(P)H fluorescence polarization imaging. bioRxiv [Preprint]. 2025 Aug 12:2025.07.28.667273. doi: 10.1101/2025.07.28.667273. PMID: 40766509; PMCID: PMC12324316.
Fischbach C, O’Hern CS, Engler AJ. Applying physical principles to cancer research. APL Bioeng. 2025 Jun 26;9(2):020402. doi: 10.1063/5.0282296. PMID: 40584819; PMCID: PMC12204716.
Whitman MA, Mantri M, Spanos E, Estroff LA, De Vlaminck I, Fischbach C. Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity. Biomaterials. 2025 Apr;315:122916. doi: 10.1016/j.biomaterials.2024.122916. Epub 2024 Oct 24. PMID: 39490060; PMCID: PMC11658005.

2024

Park S, Choi S, Shimpi AA, Estroff LA, Fischbach C, Paszek MJ. Collagen Mineralization Decreases NK Cell-Mediated Cytotoxicity of Breast Cancer Cells via Increased Glycocalyx Thickness. Adv Mater. 2024 Oct;36(43):e2311505. doi: 10.1002/adma.202311505. Epub 2024 Feb 11. PMID: 38279892; PMCID: PMC11471288.
Beeghly GF, Deng J, Fischbach C. Protocol to fabricate elastomer microwells for three-dimensional culture of primary adipocytes. STAR Protoc. 2024 Sep 20;5(3):103264. doi: 10.1016/j.xpro.2024.103264. Epub 2024 Aug 14. Erratum in: STAR Protoc. 2026 Mar 20;7(1):104437. doi: 10.1016/j.xpro.2026.104437. PMID: 39146192; PMCID: PMC11367524.
Whitman MA, Mantri M, Spanos E, Estroff LA, De Vlaminck I, Fischbach C. Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity. bioRxiv [Preprint]. 2024 Jul 23:2024.07.19.604333. doi: 10.1101/2024.07.19.604333. Update in: Biomaterials. 2025 Apr;315:122916. doi: 10.1016/j.biomaterials.2024.122916. PMID: 39091735; PMCID: PMC11291034.
Zheng Y, Wang D, Beeghly G, Fischbach C, Shattuck MD, O’Hern CS. Computational modeling of the physical features that influence breast cancer invasion into adipose tissue. APL Bioeng. 2024 Jul 3;8(3):036104. doi: 10.1063/5.0209019. PMID: 38966325; PMCID: PMC11223776.
Park S, Colville MJ, Paek JH, Shurer CR, Singh A, Secor EJ, Sailer CJ, Huang LT, Kuo JC, Goudge MC, Su J, Kim M, DeLisa MP, Neelamegham S, Lammerding J, Zipfel WR, Fischbach C, Reesink HL, Paszek MJ. Immunoengineering can overcome the glycocalyx armour of cancer cells. Nat Mater. 2024 Mar;23(3):429-438. doi: 10.1038/s41563-024-01808-0. Epub 2024 Feb 15. PMID: 38361041; PMCID: PMC11471287.
Zheng Y, Wang D, Beeghly G, Fischbach C, Shattuck MD, O’Hern CS. Computational modeling of the physical features that influence breast cancer invasion into adipose tissue. ArXiv [Preprint]. 2024 Mar 18:arXiv:2403.12293v1. Update in: APL Bioeng. 2024 Jul 03;8(3):036104. doi: 10.1063/5.0209019. PMID: 38562454; PMCID: PMC10984007.
Park S, Choi S, Shimpi AA, Estroff LA, Fischbach C, Paszek MJ. COLLAGEN MINERALIZATION DECREASES NK CELL-MEDIATED CYTOTOXICITY OF BREAST CANCER CELLS VIA INCREASED GLYCOCALYX THICKNESS. bioRxiv [Preprint]. 2024 Jan 23:2024.01.20.576377. doi: 10.1101/2024.01.20.576377. Update in: Adv Mater. 2024 Oct;36(43):e2311505. doi: 10.1002/adma.202311505. PMID: 38328161; PMCID: PMC10849468.

Gariepy

2026

Chiang AY, Gariepy AM, Leon-Martinez D, Treder KM, Schwarz EB. Desire for reversal after tubal sterilization in the United States, 2006-2023. F S Rep. 2026 Mar 23;7(2):143-149. doi: 10.1016/j.xfre.2026.02.002. PMID: 42040267; PMCID: PMC13107036.

2024

Schwarz EB, Chiang AY, Lewis CA, Gariepy AM, Reeves MF. Pregnancy after Tubal Sterilization in the United States, 2002 to 2015. NEJM Evid. 2024 Sep;3(9):EVIDoa2400023. doi: 10.1056/EVIDoa2400023. Epub 2024 Aug 27. PMID: 39189861.
Starosta A, Harris J, Gariepy A, Pathy S, Cron J. Medication abortion for adolescents in the United States: Strengthening the role of pediatric primary care providers. Perspect Sex Reprod Health. 2024 Jun;56(2):76-84. doi: 10.1111/psrh.12264. Epub 2024 Apr 25. PMID: 38661101.
Markowitz MA, Lundsberg LS, Gariepy AM. A Multidimensional and Longitudinal Exploratory Study of the Stability of Pregnancy Contexts in the United States. Womens Health Rep (New Rochelle). 2024 Mar 12;5(1):211-222. doi: 10.1089/whr.2024.0008. PMID: 38516649; PMCID: PMC10956533.

Gerhardt

2026

Deshpande M, Paniza T, Brown R, Heslin K, Patel N, Madireddy A, Rosenwaks Z, Gerhardt J. Endogenous and environmental factors that induce DNA replication defects and genomic instability in ER-negative heterozygous BRCA1 cells. Sci Rep. 2026 Mar 27;16(1):10856. doi: 10.1038/s41598-026-46028-5. PMID: 41896346; PMCID: PMC13039430.

2025

Deshpande M, Gerhardt J. Protocol to Establish Estrogen Receptor-Negative Heterozygous BRCA1 Organoids. Methods Protoc. 2025 Nov 1;8(6):127. doi: 10.3390/mps8060127. PMID: 41283387; PMCID: PMC12641787.
McCarter K, Deshpande M, Romanski P, Stratopoulou CA, Zaninovic N, Tareen M, Al-Mousawi R, James D, Madireddy A, Rosenwaks Z, Gerhardt J. Dysregulation of the actin cytoskeleton and FMRP causes polar body protrusion defects in human fragile X premutation and aged oocytes. bioRxiv [Preprint]. 2025 Feb 26:2025.02.23.639319. doi: 10.1101/2025.02.23.639319. PMID: 40060650; PMCID: PMC11888274.
Ummarino S, Poluben L, Ebralidze AK, Autiero I, Zhang Y, Paniza T, Deshpande M, Rinaldi L, Lee JD, Bassal MA, Trinh BQ, Balk SP, Flaumenhaft R, Gerhardt J, Mirkin SM, Tenen DG, Di Ruscio A. RNAs anchoring replication complex control initiation and firing of DNA replication. Res Sq [Preprint]. 2025 Jan 28:rs.3.rs-5723221. doi: 10.21203/rs.3.rs-5723221/v1. PMID: 39975922; PMCID: PMC11838740.
Niljikar M, Barreto-Galvez A, Patel S, Gagliardi JE, Kumar V, Pradeep A, Juwarwala A, Gerhardt J, Chang Y, Montagna C, Madireddy A. Polymerase Eta Recruits FANCD2 to Common Fragile Sites to Maintain Genome Stability. bioRxiv [Preprint]. 2025 Jan 8:2025.01.06.631600. doi: 10.1101/2025.01.06.631600. PMID: 39829787; PMCID: PMC11741286.

2024

Edwards MM, Wang N, Sagi I, Kinreich S, Benvenisty N, Gerhardt J, Egli D, Koren A. Parent-of-origin-specific DNA replication timing is confined to large imprinted regions. Cell Rep. 2024 Sep 24;43(9):114700. doi: 10.1016/j.celrep.2024.114700. Epub 2024 Sep 4. PMID: 39235941.
Xu S, Wang N, Zuccaro MV, Gerhardt J, Iyyappan R, Scatolin GN, Jiang Z, Baslan T, Koren A, Egli D. DNA replication in early mammalian embryos is patterned, predisposing lamina-associated regions to fragility. Nat Commun. 2024 Jun 19;15(1):5247. doi: 10.1038/s41467-024-49565-7. PMID: 38898078; PMCID: PMC11187207.
Gerhardt J. The discovery of simple repeats that cause complex disorders. Nat Rev Mol Cell Biol. 2024 Mar;25(3):161. doi: 10.1038/s41580-023-00666-z. PMID: 37697011.

Giordano

2026

Giesy SL, Opgenorth J, Rodriguez-Jimenez S, Baumgard LH, Swartz TH, Mamedova LK, Bradford BJ, Ferro LN, Overton TR, Rial C, Giordano JO, Boisclair YR. Effect of conditions and diseases associated with systemic inflammation on the plasma concentration of growth differentiation factor 15 (GDF15) in dairy cows. J Dairy Sci. 2026 Oct 22:S0022-0302(26)03373-4. doi: 10.3168/jds.2026-29128. Epub ahead of print. PMID: 42913831.
Rial C, Stangaferro ML, Thomas MJ, Giordano JO. Economic effects of automated health monitoring based on sensors versus visual observation for dairy cows in early lactation. J Dairy Sci. 2026 Jun;109(6):6497-6515. doi: 10.3168/jds.2025-27516. Epub 2026 Mar 17. PMID: 41850362.
Laplacette AL, Stangaferro ML, Thomas MJ, Giordano JO. Effect on first-service outcomes of a modified Double-Ovsynch protocol designed to increase fertility through insemination of cows in estrus and a targeted intervention for nonestrus cows. J Dairy Sci. 2026 Apr;109(4):4516-4533. doi: 10.3168/jds.2025-27396. Epub 2026 Jan 20. PMID: 41570913.
Giordano JO, Laplacette AL. Present and future opportunities for artificial intelligence applications in dairy cattle reproduction. Anim Front. 2026 Feb 15;16(2):86-98. doi: 10.1093/af/vfag007. PMID: 42137897; PMCID: PMC13171239.
Mörig F, Drillich M, Burnett TA, Bruinjé TC, Giordano JO, Madureira AML, Borchardt S. Evaluation of the association between automated estrus alerts from activity monitoring systems in early lactation with reproductive performance in lactating Holstein cows: A meta-analysis. J Dairy Sci. 2026 Feb;109(2):1968-1977. doi: 10.3168/jds.2025-27545. Epub 2025 Nov 24. PMID: 41297596.
Giesy SL, Butler WR, Overton TR, Rial C, Giordano JO, Boisclair YR. Effect of metabolic disturbances on the plasma concentration and hepatic expression of the appetite-reducing hormone growth differentiation factor 15 (GDF15) in dairy cows. J Dairy Sci. 2026 Jan;109(1):781-794. doi: 10.3168/jds.2025-27481. Epub 2025 Oct 21. PMID: 41130397.

2025

Perez MM, Cabrera E, Rial C, You Y, Wang Y, Weinberger K, Nydam DV, Giordano JO. Screening and selection of a machine learning algorithm for development of a model to select cows for clinical examination using data from automated health monitoring technologies and other predictors of cow health. J Dairy Sci. 2025 Dec;108(12):13720-13738. doi: 10.3168/jds.2025-26511. Epub 2025 Oct 1. PMID: 41043704.
Cabrera VE, Bewley J, Breunig M, Breunig T, Cooley W, De Vries A, Fourdraine R, Giordano JO, Gong Y, Greenfield R, Hu H, Lenkaitis A, Niu M, Noronha EAF, Sullivan M. Data Integration and Analytics in the Dairy Industry: Challenges and Pathways Forward. Animals (Basel). 2025 Jan 24;15(3):329. doi: 10.3390/ani15030329. PMID: 39943099; PMCID: PMC11816260.
Laplacette AL, Rial C, Sitko E, Perez MM, Tompkins S, Stangaferro ML, Thomas MJ, Giordano JO. Delaying induction of ovulation and timed artificial insemination in a Double-Ovsynch protocol increased expression of estrus and altered first-service reproductive outcomes of lactating dairy cows. J Dairy Sci. 2025 Jan;108(1):1103-1124. doi: 10.3168/jds.2024-24994. Epub 2024 Oct 15. PMID: 39414011.

2024

Rial C, Stangaferro ML, Thomas MJ, Giordano JO. Effect of automated health monitoring based on rumination, activity, and milk yield alerts versus visual observation on herd health monitoring and performance outcomes. J Dairy Sci. 2024 Dec;107(12):11576-11596. doi: 10.3168/jds.2024-25256. Epub 2024 Sep 27. PMID: 39343202.
Sitko EM, Laplacette A, Duhatschek D, Rial C, Perez MM, Tompkins S, Kerwin AL, Giordano JO. Reproductive physiological outcomes of dairy cows with different genomic merit for fertility: Biomarkers, uterine health, endocrine status, estrus features, and response to ovarian synchronization. J Dairy Sci. 2024 Oct;107(10):8670-8687. doi: 10.3168/jds.2023-24376. Epub 2024 Jun 6. PMID: 38851573.
Rial C, Hussain I, Hoff R, Tompkins S, Erickson D, Branen J, Giordano JO. Development and evaluation of a lateral flow-based portable optical system for determination of the pregnancy status of dairy cows. J Dairy Sci. 2024 Oct;107(10):8642-8653. doi: 10.3168/jds.2024-24899. Epub 2024 May 31. PMID: 38825130.
Laplacette AL, Rial C, Magaña Baños GS, García Escalera JA, Torres S, Kerwin A, Giordano JO. Effect of a targeted reproductive management program based on automated detection of estrus during the voluntary waiting period on reproductive performance of lactating dairy cows. Theriogenology. 2024 Sep 1;225:130-141. doi: 10.1016/j.theriogenology.2024.05.030. Epub 2024 May 22. PMID: 38805995.
Sitko EM, Laplacette A, Duhatschek D, Rial C, Perez MM, Tompkins S, Kerwin AL, Domingues RR, Wiltbank MC, Giordano JO. Ovarian function and endocrine phenotypes of lactating dairy cows during the estrous cycle are associated with genomic-enhanced predictions of fertility potential. J Dairy Sci. 2024 Sep;107(9):7352-7370. doi: 10.3168/jds.2023-24378. Epub 2024 Apr 19. PMID: 38642658.
Rial C, Giordano JO. Combining reproductive outcomes predictors and automated estrus alerts recorded during the voluntary waiting period identified subgroups of cows with different reproductive performance potential. J Dairy Sci. 2024 Sep;107(9):7299-7316. doi: 10.3168/jds.2023-24309. Epub 2024 Apr 19. PMID: 38642654.
Garcia NL, Rodrigues-Motta M, Migon HS, Petkova E, Tarpey T, Ogden RT, Giordano JO, Perez MM. Unsupervised Bayesian classification for models with scalar and functional covariates. J R Stat Soc Ser C Appl Stat. 2024 Feb 7;73(3):658-681. doi: 10.1093/jrsssc/qlae006. PMID: 39072300; PMCID: PMC11271982.

Grimson

2026

Chobirko JD, Feschotte C, Grimson A. Cis-regulatory co-option of a transposon family reinforces cell identity across the immune system. EMBO J. 2026 Oct 28. doi: 10.1038/s44318-026-00938-2. Epub ahead of print. PMID: 42957909.
Dziubek A, Grimson A. The Identification and Impact of 3’UTR Regulatory Variants on Phenotype and Disease. Annu Rev Genet. 2026 Aug 21. doi: 10.1146/annurev-genet-011626-024110. Epub ahead of print. PMID: 42628125.
Nishida C, Kobayashi M, Syed A, Kramer P, Cheng H, Wenzel PL, Osato M, Chobirko JD, Grimson A, Slukvin II, Davis BR, Yoshimoto M. RUNX1+23 enhancer marks erythro-megakaryocyte lineages in early waves of hematopoiesis in human ESC differentiation. Blood Adv. 2026 Aug 11;10(15):5454-5459. doi: 10.1182/bloodadvances.2025018365. PMID: 42275564; PMCID: PMC13469946.
Carro MLM, Dziubek A, Touey-May A, Popkowski EA, Abdelmassih M, Simon LE, Tanis SL, Ahmed F, Grenier JK, Grimson A, Cohen PE. Argonaute proteins orchestrate Meiotic Sex Chromosome Inactivation and timing of the spermatogenic transcriptional program. PLoS Genet. 2026 Jun 29;22(6):e1012217. doi: 10.1371/journal.pgen.1012217. PMID: 42371982; PMCID: PMC13336459.
Tabilas C, Venturi V, Kean C, Minervina A, Thomas PG, Grimson A, Grenier JK, Davenport MP, Smith NL, Rudd BD. Single-cell gene expression and TCR profiling reveal age-related differences in recent thymic emigrants. iScience. 2026 Apr 1;29(5):115582. doi: 10.1016/j.isci.2026.115582. PMID: 42023153; PMCID: PMC13098507.
Geber A, Groff B, McMurry J, Laniewski N, Tyrlik A, Kean C, Wang R, Castro-Melendez D, Narvaez-Miranda J, Vance N, Pryhuber G, Mosmann T, Rudd BD, Thakar J, Topham DJ, Grimson A, Scheible K. Single cell analysis of neonatal naïve CD8α + T cells reveals novel subsets bridging the innate-adaptive spectrum. bioRxiv [Preprint]. 2026 Mar 9:2026.03.05.706693. doi: 10.64898/2026.03.05.706693. PMID: 41959467; PMCID: PMC13060856.

2025

Chobirko JD, Feschotte C, Grimson A. Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system. bioRxiv [Preprint]. 2025 Dec 25:2025.12.22.696042. doi: 10.64898/2025.12.22.696042. Update in: EMBO J. 2026 Oct 28. doi: 10.1038/s44318-026-00938-2. PMID: 41509290; PMCID: PMC12776137.
Zhu H, Ganapathi Sankaran D, Smith NL, Daly CWP, Yee Mon K, Tabilas C, Wissink EM, Rudd BD, Grimson A. An efficient framework to decipher microRNA regulatory programs applied to T cells. Genes Immun. 2025 Oct;26(5):486-496. doi: 10.1038/s41435-025-00351-5. Epub 2025 Aug 18. PMID: 40825847; PMCID: PMC12527941.
Gardella AE, Eweis-LaBolle D, Loy CJ, Belcher ED, Lenz JS, Franconi CJ, Scofield SY, Grimson A, Hanson MR, De Vlaminck I. Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome. Proc Natl Acad Sci U S A. 2025 Aug 19;122(33):e2507345122. doi: 10.1073/pnas.2507345122. Epub 2025 Aug 11. PMID: 40789036; PMCID: PMC12377778.
Ganapathi Sankaran D, Zhu H, Maymi VI, Forlastro IM, Jiang Y, Laniewski N, Scheible KM, Rudd BD, Grimson A. Gene-regulatory programs that specify age-related differences during thymocyte development. Cell Rep. 2025 Jul 22;44(7):115903. doi: 10.1016/j.celrep.2025.115903. Epub 2025 Jun 25. PMID: 40570375.
West JD, Smith HJ, Vu LT, Fogarty EA, Matreyek KA, Fowler DM, Grimson A. The quantitative impact of 3’UTRs on gene expression. Nucleic Acids Res. 2025 Jun 20;53(12):gkaf568. doi: 10.1093/nar/gkaf568. PMID: 40586305; PMCID: PMC12207410.
Zhang S, Jahanbani F, Chander V, Kjellberg M, Liu M, Glass KA, Iu DS, Ahmed F, Li H, Maynard RD, Chou T, Cooper-Knock J, Zhang MJ, Thota D, Zeineh M, Grenier JK, Grimson A, Hanson MR, Snyder MP. Dissecting the genetic complexity of myalgic encephalomyelitis/chronic fatigue syndrome via deep learning-powered genome analysis. medRxiv [Preprint]. 2025 May 11:2025.04.15.25325899. doi: 10.1101/2025.04.15.25325899. PMID: 40321247; PMCID: PMC12047926.
Carro MLM, Dziubek A, Touey A, Popkowski EA, Abdelmassih M, Simon L, Tanis S, Ahmed F, Grenier JK, Grimson A, Cohen PE. Argonaute proteins regulate the timing of the spermatogenic transcriptional program. bioRxiv [Preprint]. 2025 Jan 1:2024.12.31.630913. doi: 10.1101/2024.12.31.630913. PMID: 39803480; PMCID: PMC11722363.

2024

Iu DS, Maya J, Vu LT, Fogarty EA, McNairn AJ, Ahmed F, Franconi CJ, Munn PR, Grenier JK, Hanson MR, Grimson A. Transcriptional reprogramming primes CD8+ T cells toward exhaustion in Myalgic encephalomyelitis/chronic fatigue syndrome. Proc Natl Acad Sci U S A. 2024 Dec 10;121(50):e2415119121. doi: 10.1073/pnas.2415119121. Epub 2024 Dec 2. PMID: 39621903; PMCID: PMC11648872.
Yee Mon KJ, Kim S, Dai Z, West JD, Zhu H, Jain R, Grimson A, Rudd BD, Singh A. Functionalized nanowires for miRNA-mediated therapeutic programming of naïve T cells. Nat Nanotechnol. 2024 Aug;19(8):1190-1202. doi: 10.1038/s41565-024-01649-7. Epub 2024 Apr 29. PMID: 38684809; PMCID: PMC11330359.
Maymí VI, Zhu H, Jager M, Johnson S, Getchell R, Casey JW, Grenier JK, Wherry EJ, Smith NL, Grimson A, Rudd BD. Neonatal CD8+ T Cells Resist Exhaustion during Chronic Infection. J Immunol. 2024 Mar 1;212(5):834-843. doi: 10.4049/jimmunol.2300396. PMID: 38231127; PMCID: PMC11298781.
Ascenção C, Sims JR, Dziubek A, Comstock W, Fogarty EA, Badar J, Freire R, Grimson A, Weiss RS, Cohen PE, Smolka MB. A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation. Elife. 2024 Feb 23;12:RP90887. doi: 10.7554/eLife.90887. PMID: 38391183; PMCID: PMC10942628.
Watson NB, Patel RK, Kean C, Veazey J, Oyesola OO, Laniewski N, Grenier JK, Wang J, Tabilas C, Yee Mon KJ, McNairn AJ, Peng SA, Wesnak SP, Nzingha K, Davenport MP, Tait Wojno ED, Scheible KM, Smith NL, Grimson A, Rudd BD. The gene regulatory basis of bystander activation in CD8+ T cells. Sci Immunol. 2024 Feb 23;9(92):eadf8776. doi: 10.1126/sciimmunol.adf8776. Epub 2024 Feb 23. PMID: 38394230.
Vu LT, Ahmed F, Zhu H, Iu DSH, Fogarty EA, Kwak Y, Chen W, Franconi CJ, Munn PR, Tate AE, Levine SM, Stevens J, Mao X, Shungu DC, Moore GE, Keller BA, Hanson MR, Grenier JK, Grimson A. Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation. Cell Rep Med. 2024 Jan 16;5(1):101373. doi: 10.1016/j.xcrm.2023.101373. PMID: 38232699; PMCID: PMC10829790.

Jaffrey

2026

Liu S, Malik AF, Chien R, Liu J, Nicholson LS, Xu J, Didehvar K, Rai V, Le Rouzic VP, Martínez-Rivera A, Boulias K, Wang B, Rajadhyaksha AM, Tao YX, Greer EL, Jaffrey SR, Pan YX. Reversible m 6 Am methylation of snRNA by FTO controls morphine reward and tolerance without altering analgesia. bioRxiv [Preprint]. 2026 Aug 12:2026.08.06.743062. doi: 10.64898/2026.08.06.743062. PMID: 42845381; PMCID: PMC13640593.
Nalavade R, Mirza AH, Jaffrey SR. Validation of the mRNA epitranscriptome: SCARPET reveals that mapped m1A sites are inosine. EMBO Rep. 2026 Aug;27(15):4357-4375. doi: 10.1038/s44319-026-00840-2. Epub 2026 Jun 23. PMID: 42337368; PMCID: PMC13458256.
Park KS, Dey SK, Nalavade R, Mirza AH, Hou Q, Roque MAM, Oleynikov M, Litke JL, Jaffrey SR. A multivalent RNA affinity tag enables selective purification of tagged RNAs and bound proteins. Nucleic Acids Res. 2026 Jul 17;54(14):gkag735. doi: 10.1093/nar/gkag735. PMID: 42531073; PMCID: PMC13421773.
Liu JF, Jaffrey SR. Transcription Start Site Choice Regulates m6A Stoichiometry in Cap-Proximal Regions. Genes (Basel). 2026 May 31;17(6):653. doi: 10.3390/genes17060653. PMID: 42353811; PMCID: PMC13298977.
Luo H, Kharas MG, Jaffrey SR. N6-Methyladenosine: an RNA modification as a central regulator of cancer. Nat Rev Cancer. 2026 Feb;26(2):118-136. doi: 10.1038/s41568-025-00889-6. Epub 2025 Dec 8. PMID: 41360987; PMCID: PMC13142248.

2025

Ohnezeit D, Loliashvili E, Putzel G, Verstraten R, Liu J, Nicholson LS, Pironti A, Jaffrey SR, Depledge DP, Wilson AC. Establishing benchmarks for quantitative mapping of m 6 A by Nanopore Direct RNA Sequencing. bioRxiv [Preprint]. 2025 Nov 6:2025.11.02.686099. doi: 10.1101/2025.11.02.686099. PMID: 41278928; PMCID: PMC12636606.
Hou Q, Oleynikov M, Mei X, Dong L, Hagen T, Jaffrey SR. A portable poison exon for small-molecule control of mammalian gene expression. Nat Methods. 2025 Nov;22(11):2337-2348. doi: 10.1038/s41592-025-02860-7. Epub 2025 Nov 3. PMID: 41184552.
Pandey K, Poh HX, Jaffrey SR. Why does the m6A writer complex require so many proteins? PLoS Biol. 2025 Sep 15;23(9):e3003386. doi: 10.1371/journal.pbio.3003386. PMID: 40953081; PMCID: PMC12453181.
Chen Z, Jiang H, Yuan L, Yao T, Rong X, Gao W, Zeng C, He L, Yin Y, Jaffrey SR, Zhao F, Zhang J, Xu P, Li X. Photoactivatable RNA Tags for Subcellular Photolabeling of RNA. J Am Chem Soc. 2025 Sep 3;147(35):31650-31661. doi: 10.1021/jacs.5c07380. Epub 2025 Aug 25. PMID: 40852906.
Hughes RO, Davis HJ, Nease LA, Zumbo P, Danielli M, Tran W, Maidhof K, Kosmas K, Kanshin E, Murakami S, Cascio MG, Church KP, Aguirre KN, Delclaux I, Slack FJ, Vlachos IS, Ueberheide B, Jaffrey SR, Erhard F, Banh R, Betel D, Piskounova E. tRNA modifications are required for stress granule formation and melanoma metastasis. bioRxiv [Preprint]. 2025 Aug 25:2025.08.20.671337. doi: 10.1101/2025.08.20.671337. PMID: 40909646; PMCID: PMC12407792.
Murakami S, Olarerin-George AO, Liu JF, Zaccara S, Hawley B, Jaffrey SR. m6A alters ribosome dynamics to initiate mRNA degradation. Cell. 2025 Jul 10;188(14):3728-3743.e20. doi: 10.1016/j.cell.2025.04.020. Epub 2025 May 6. PMID: 40328256; PMCID: PMC12255529.
Linder B, Sharma P, Wu J, Birbaumer T, Eggers C, Murakami S, Ott RE, Fenzl K, Vorgerd H, Erhard F, Jaffrey SR, Leidel SA, Steinmetz LM. tRNA modifications tune m6A-dependent mRNA decay. Cell. 2025 Jul 10;188(14):3715-3727.e13. doi: 10.1016/j.cell.2025.04.013. Epub 2025 Apr 30. PMID: 40311619; PMCID: PMC12255531.
Liu JF, Hawley BR, Nicholson LS, Jaffrey SR. Decoding m6Am by simultaneous transcription-start mapping and methylation quantification. Elife. 2025 Mar 31;13:RP104139. doi: 10.7554/eLife.104139. PMID: 40162895; PMCID: PMC11957539.
Kam CW, Dumelie JG, Ciceri G, Yang WY, Disney MD, Studer L, Jaffrey SR. Sustained Epigenetic Reactivation in Fragile X Neurons with an RNA-Binding Small Molecule. Genes (Basel). 2025 Feb 25;16(3):278. doi: 10.3390/genes16030278. PMID: 40149430; PMCID: PMC11942054.
Verhamme R, Jansens RJJ, Liu J, Van Raemdonck F, Van Waesberghe C, Nicholson L, Jaffrey SR, Favoreel HW. The pseudorabies virus UL13 protein kinase triggers phosphorylation of the RNA demethylase FTO, which is associated with FTO-dependent suppression of interferon-stimulated gene expression. J Virol. 2025 Feb 25;99(2):e0201924. doi: 10.1128/jvi.02019-24. Epub 2025 Jan 10. PMID: 39791911; PMCID: PMC11852732.
Liu JF, Hawley BR, Nicholson LS, Jaffrey SR. Decoding m6Am by simultaneous transcription-start mapping and methylation quantification. bioRxiv [Preprint]. 2025 Feb 21:2024.10.16.618717. doi: 10.1101/2024.10.16.618717. Update in: Elife. 2025 Mar 31;13:RP104139. doi: 10.7554/eLife.104139. PMID: 39677659; PMCID: PMC11642800.
Wu J, Jaffrey SR. Live-Cell Imaging of mRNA Using a Pepper RNA Tag. Methods Mol Biol. 2025;2875:1-7. doi: 10.1007/978-1-0716-4248-1_1. PMID: 39535635.

2024

Oleynikov M, Jaffrey SR. RNA tertiary structure and conformational dynamics revealed by BASH MaP. Elife. 2024 Dec 3;13:RP98540. doi: 10.7554/eLife.98540. PMID: 39625751; PMCID: PMC11614387.
Liu JF, Jaffrey SR. Dinoflagellate mRNA is pervasively modified with m1A. EMBO Rep. 2024 Nov;25(11):4634-4635. doi: 10.1038/s44319-024-00263-x. Epub 2024 Sep 20. PMID: 39304776; PMCID: PMC11549392.
Hagen T, Litke JL, Nasir N, Hou Q, Jaffrey SR. Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function. Cell Chem Biol. 2024 Oct 17;31(10):1827-1838.e7. doi: 10.1016/j.chembiol.2024.07.017. Epub 2024 Aug 26. PMID: 39191249; PMCID: PMC11680490.
Unti MJ, Doetsch L, Jaffrey SR. A circular split nanoluciferase reporter for validating and screening putative internal ribosomal entry site elements. RNA. 2024 Oct 16;30(11):1529-1540. doi: 10.1261/rna.080008.124. PMID: 39103230; PMCID: PMC11482608.
Oleynikov M, Jaffrey SR. RNA tertiary structure and conformational dynamics revealed by BASH MaP. bioRxiv [Preprint]. 2024 Aug 19:2024.04.11.589009. doi: 10.1101/2024.04.11.589009. Update in: Elife. 2024 Dec 03;13:RP98540. doi: 10.7554/eLife.98540. PMID: 38645201; PMCID: PMC11030352.
Zaccara S, Jaffrey SR. Understanding the redundant functions of the m6A-binding YTHDF proteins. RNA. 2024 Apr 16;30(5):468-481. doi: 10.1261/rna.079988.124. PMID: 38531646; PMCID: PMC11019742.
Dumelie JG, Chen Q, Miller D, Attarwala N, Gross SS, Jaffrey SR. Biomolecular condensates create phospholipid-enriched microenvironments. Nat Chem Biol. 2024 Mar;20(3):302-313. doi: 10.1038/s41589-023-01474-4. Epub 2023 Nov 16. PMID: 37973889; PMCID: PMC10922641.
Mirza AH, Bram Y, Schwartz RE, Jaffrey SR. SCARPET: site-specific quantification of methylated and nonmethylated adenosines reveals m6A stoichiometry. RNA. 2024 Feb 16;30(3):308-324. doi: 10.1261/rna.079776.123. PMID: 38190635; PMCID: PMC10870371.
Zhang Z, Rong X, Xie T, Li Z, Song H, Zhen S, Wang H, Wu J, Jaffrey SR, Li X. Fluorogenic CRISPR for genomic DNA imaging. Nat Commun. 2024 Jan 31;15(1):934. doi: 10.1038/s41467-024-45163-9. PMID: 38296979; PMCID: PMC10831063.
Unti MJ, Jaffrey SR. Highly efficient cellular expression of circular mRNA enables prolonged protein expression. Cell Chem Biol. 2024 Jan 18;31(1):163-176.e5. doi: 10.1016/j.chembiol.2023.09.015. Epub 2023 Oct 25. PMID: 37883972; PMCID: PMC10841545.

James

2025

McCarter K, Deshpande M, Romanski P, Stratopoulou CA, Zaninovic N, Tareen M, Al-Mousawi R, James D, Madireddy A, Rosenwaks Z, Gerhardt J. Dysregulation of the actin cytoskeleton and FMRP causes polar body protrusion defects in human fragile X premutation and aged oocytes. bioRxiv [Preprint]. 2025 Feb 26:2025.02.23.639319. doi: 10.1101/2025.02.23.639319. PMID: 40060650; PMCID: PMC11888274.

Johnson, Elizabeth

2026

Solomon Z, Eno M, Thompson SC, Rager SL, Jin JC, Zeng MY, Keerthy D, Worgall S, Johnson EL, Heras A. Increased S. epidermidis in the airway-gut microbiome of infants with bronchopulmonary dysplasia. bioRxiv [Preprint]. 2026 Apr 4:2026.04.03.715941. doi: 10.64898/2026.04.03.715941. PMID: 41959121; PMCID: PMC13060358.

2024

Lee MT, Tan X, Le HH, Besler K, Thompson S, Harris-Tryon T, Johnson EL. Gut bacterial sphingolipid production modulates dysregulated skin lipid homeostasis. bioRxiv [Preprint]. 2024 Dec 30:2024.12.29.629238. doi: 10.1101/2024.12.29.629238. PMID: 39803564; PMCID: PMC11722302.
Bosch TCG, Wigley M, Colomina B, Bohannan B, Meggers F, Amato KR, Azad MB, Blaser MJ, Brown K, Dominguez-Bello MG, Ehrlich SD, Elinav E, Finlay BB, Geddie K, Geva-Zatorsky N, Giles-Vernick T, Gros P, Guillemin K, Haraoui LP, Johnson E, Keck F, Lorimer J, McFall-Ngai MJ, Nichter M, Pettersson S, Poinar H, Rees T, Tropini C, Undurraga EA, Zhao L, Melby MK. The potential importance of the built-environment microbiome and its impact on human health. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2313971121. doi: 10.1073/pnas.2313971121. Epub 2024 Apr 25. PMID: 38662573; PMCID: PMC11098107.
Xiao X, Le HH, Lee M-T, Lamm D, Johnson EL, Brito IL. Prevotella copri variants among a single host diverge in sphingolipid production. mBio. 2024 Feb 14;15(2):e0240923. doi: 10.1128/mbio.02409-23. Epub 2024 Jan 18. PMID: 38236049; PMCID: PMC10865984.

Johnson, Patricia

2025

Francoeur L, Scoville DM, Ahern JG, Johnson PA. Characterization of Persistency of Lay in Laying Hens. Biol Reprod. 2025 Oct 8:ioaf227. doi: 10.1093/biolre/ioaf227. Epub ahead of print. PMID: 41060289.

2024

Francoeur L, Scoville DM, Johnson PA. Investigations of the function of AMH in granulosa cells in hens. Gen Comp Endocrinol. 2024 Apr 1;349:114454. doi: 10.1016/j.ygcen.2024.114454. Epub 2024 Jan 22. PMID: 38266936.

Keeney

2026

Xu J, Keeney S. Controlling Meiotic Double-Strand Break Formation in Mice: A Web of Multivalent Protein-Protein Interactions. Bioessays. 2026 Oct;48(10):e70190. doi: 10.1002/bies.70190. PMID: 42814036; PMCID: PMC13637975.
Ontoso D, Mehta M, Shabro A, Dittmar J, Reid RJD, Rothstein R, Nitiss JL, Keeney S. A multispecies toolkit of TOP2 hypercleavage mutants for studying topoisomerase II-mediated DNA damage. Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2616452123. doi: 10.1073/pnas.2616452123. Epub 2026 Sep 1. PMID: 42679034; PMCID: PMC13552660.
Lukaszewicz A, Wilson TE, Kim S, Keeney S, Jasin M. MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice. Genes Dev. 2026 Aug 26;40(17-18):1466-1483. doi: 10.1101/gad.353693.126. PMID: 42538288; PMCID: PMC13532658.
Ontoso D, Mehta M, Shabro A, Dittmar J, Reid RJD, Rothstein R, Nitiss JL, Keeney S. A multi-species toolkit of TOP2 hypercleavage mutants for studying topoisomerase II-mediated DNA damage. bioRxiv [Preprint]. 2026 Aug 11:2026.05.09.723998. doi: 10.64898/2026.05.09.723998. Update in: Proc Natl Acad Sci U S A. 2026 Sep 8;123(36):e2616452123. doi: 10.1073/pnas.2616452123. PMID: 42182284; PMCID: PMC13192990.
Lukaszewicz A, Wilson TE, Kim S, Keeney S, Jasin M. MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice. bioRxiv [Preprint]. 2026 Feb 15:2026.02.11.705388. doi: 10.64898/2026.02.11.705388. Update in: Genes Dev. 2026 Aug 26;40(17-18):1466-1483. doi: 10.1101/gad.353693.126. PMID: 41726871; PMCID: PMC12918824.
Kim DS, Goo B, Veerapaneni P, Chouhaita R, Cyriac N, Ogbi M, Fulton DJ, Zhang W, Long X, Guha A, Keeney S, Coffey P, Rice RD, Gallo DR, Patel VS, Lee R, Kim HW, Shi H, Weintraub NL. A regulatory role of novel long non-coding RNA, BAZ1A-AS1, in vascular smooth muscle cell functions during neointima formation in human saphenous veins. bioRxiv [Preprint]. 2026 Feb 5:2026.02.03.703576. doi: 10.64898/2026.02.03.703576. PMID: 41676513; PMCID: PMC12889732.

2025

Arter M, Vedanayagam J, Lu M, Diop M, Liu K, Lai EC, Keeney S. Structure-informed evolutionary analysis of the meiotic recombination machinery. bioRxiv [Preprint]. 2025 Nov 10:2025.11.07.687317. doi: 10.1101/2025.11.07.687317. PMID: 41292753; PMCID: PMC12642689.
Kim S, Alnaser HF, Keeney S, Murakami H. Insight into meiotic DNA end resection: Mechanisms and regulation. DNA Repair (Amst). 2025 Sep;153:103886. doi: 10.1016/j.dnarep.2025.103886. Epub 2025 Aug 15. PMID: 40850049; PMCID: PMC12453631.
Kim S, Yamada S, Li T, Canasto-Chibuque C, Kim JH, Marcet-Ortega M, Xu J, Eng DY, Feeney L, Petrini JHJ, Keeney S. Mouse MRE11-RAD50-NBS1 is needed to start and extend meiotic DNA end resection. Nat Commun. 2025 Apr 16;16(1):3613. doi: 10.1038/s41467-025-57928-x. PMID: 40240347; PMCID: PMC12003770.
Zheng Z, Zheng L, Arter M, Liu K, Yamada S, Ontoso D, Kim S, Keeney S. Reconstitution of SPO11-dependent double-strand break formation. Nature. 2025 Mar;639(8055):784-791. doi: 10.1038/s41586-025-08601-2. Epub 2025 Feb 19. PMID: 39972129; PMCID: PMC11922745.
Huang PC, Hong S, Alnaser HF, Mimitou EP, Kim KP, Murakami H, Keeney S. Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30. EMBO J. 2025 Jan;44(1):200-224. doi: 10.1038/s44318-024-00318-8. Epub 2024 Nov 29. PMID: 39613969; PMCID: PMC11695836.
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S. Cryo-EM structures of the Spo11 core complex bound to DNA. Nat Struct Mol Biol. 2025 Jan;32(1):113-124. doi: 10.1038/s41594-024-01382-8. Epub 2024 Sep 20. PMID: 39304764; PMCID: PMC11746154.

2024

Zheng Z, Zheng L, Arter M, Liu K, Yamada S, Ontoso D, Kim S, Keeney S. Reconstitution of SPO11-dependent double-strand break formation. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.624382. doi: 10.1101/2024.11.20.624382. Update in: Nature. 2025 Mar;639(8055):784-791. doi: 10.1038/s41586-025-08601-2. PMID: 39605552; PMCID: PMC11601517.
Yu Y, Wang J, Liu K, Zheng Z, Arter M, Claeys Bouuaert C, Pu S, Patel DJ, Keeney S. Cryo-EM structures of the Spo11 core complex bound to DNA. Nat Struct Mol Biol. 2024 Sep 20. doi: 10.1038/s41594-024-01382-8. Epub ahead of print. PMID: 39304764.
Arter M, Keeney S. Divergence and conservation of the meiotic recombination machinery. Nat Rev Genet. 2024 May;25(5):309-325. doi: 10.1038/s41576-023-00669-8. Epub 2023 Nov 30. PMID: 38036793.
Dereli I, Telychko V, Papanikos F, Raveendran K, Xu J, Boekhout M, Stanzione M, Neuditschko B, Imjeti NS, Selezneva E, Tuncay H, Demir S, Giannattasio T, Gentzel M, Bondarieva A, Stevense M, Barchi M, Schnittger A, Weir JR, Herzog F, Keeney S, Tóth A. Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes. Nat Commun. 2024 Apr 5;15(1):2941. doi: 10.1038/s41467-024-47020-1. PMID: 38580643; PMCID: PMC10997794.

Kim Lab

2025

Matias NR, Gallicchio L, Lu D, Kim JJ, Perez J, Detweiler AM, Lu C, Bolival B, Fuller MT. A cell type-specific surveillance complex represses cryptic promoters during differentiation in an adult stem cell lineage. Genes Dev. 2025 Aug 6;. doi: 10.1101/gad.352747.125. [Epub ahead of print] PubMed PMID: 40769719; PubMed Central PMCID: PMC12333557.
Kim JJ. Not all CBXs are created equal: A role for the disordered central region of CBX4 in pediatric glioma. Mol Cell. 2025 Jun 5;85(11):2061-2063. doi: 10.1016/j.molcel.2025.05.016. PubMed PMID: 40480193.
Harris DE, Kim JJ, Stern SR, Vicars HM, Matias NR, Gallicchio L, Baker CC, Fuller MT. An RNA-binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ cell lineage. Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2418279122. doi: 10.1073/pnas.2418279122. Epub 2025 May 16. PubMed PMID: 40377994; PubMed Central PMCID: PMC12107169.

2024

Harris DE, Kim JJ, Stern SR, Vicars HM, Matias NR, Gallicchio L, Baker CC, Fuller MT. An RNA binding regulatory cascade controls the switch from proliferation to differentiation in the Drosophila male germ line stem cell lineage. bioRxiv. 2024 Sep 6;. doi: 10.1101/2024.09.06.611673. PubMed PMID: 39282418; PubMed Central PMCID: PMC11398533.

Lee

2026

Gopal S, Chaturbedi A, Ramachandrula T, OuYang J, Rodell R, Lee SS. A somatic checkpoint through NHR-49/HNF4α governs reproductive investment and longevity in C. elegans. Nat Commun. 2026 Aug 22;17(1):10046. doi: 10.1038/s41467-026-77056-4. PMID: 42768050; PMCID: PMC13594228.
Chang HY, Heinke CL, Lee SS. Molecular insights into diverse heat hormesis regimens in Caenorhabditis elegans. Genetics. 2026 Mar 4;232(3):iyag019. doi: 10.1093/genetics/iyag019. PMID: 41677572; PMCID: PMC13017708.
Chaturbedi A, Heinke CL, Lee SS. Lysosomal activation leaves a lasting memory. Trends Genet. 2026 Feb;42(2):119-121. doi: 10.1016/j.tig.2025.11.005. Epub 2025 Dec 5. PMID: 41352989.

2025

Chaturbedi A, Lee SS. Different gametogenesis states uniquely impact longevity in Caenorhabditis elegans. Nat Commun. 2025 Oct 21;16(1):9300. doi: 10.1038/s41467-025-64341-x. PMID: 41120259; PMCID: PMC12541034.
Lee SS, Gopal S, Chaturbedi A, Ramachandrula T, OuYang J, Rodell R. A somatic checkpoint through NHR-49/HNF4α governs reproductive investment and longevity in C. elegans. Res Sq [Preprint]. 2025 Sep 3:rs.3.rs-7217416. doi: 10.21203/rs.3.rs-7217416/v1. PMID: 40951264; PMCID: PMC12425103.
Gopal S, Chaturbedi A, Ramachandrula T, OuYang J, Rodell R, Lee SS. Nuclear Hormone Receptor NHR-49/HNF4α Couples Fertility Regulation to Resource Allocation and Longevity in C. elegans. bioRxiv [Preprint]. 2025 Jul 18:2025.07.14.664468. doi: 10.1101/2025.07.14.664468. PMID: 40791495; PMCID: PMC12338712.
Greer EL, Lee SS, Prahlad V. Chromatin and epigenetics in aging biology. Genetics. 2025 May 8;230(1):iyaf055. doi: 10.1093/genetics/iyaf055. PMID: 40202900.
Chang HY, McMurry SE, Ma S, Mansour CA, Schwab SMT, Danko CG, Lee SS. Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in Caenorhabditis elegans. bioRxiv [Preprint]. 2025 Mar 14:2025.03.11.642714. doi: 10.1101/2025.03.11.642714. PMID: 40161833; PMCID: PMC11952391.

2024

Emerson FJ, Chiu C, Lin LY, Riedel CG, Zhu M, Lee SS. The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans. Nat Commun. 2024 Mar 14;15(1):2320. doi: 10.1038/s41467-024-46510-6. PMID: 38485937; PMCID: PMC10940595.
Fox BW, Helf MJ, Burkhardt RN, Artyukhin AB, Curtis BJ, Palomino DF, Schroeder AF, Chaturbedi A, Tauffenberger A, Wrobel CJJ, Zhang YK, Lee SS, Schroeder FC. Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans. Nat Commun. 2024 Feb 19;15(1):1520. doi: 10.1038/s41467-024-45782-2. Erratum in: Nat Commun. 2024 Jul 19;15(1):6090. doi: 10.1038/s41467-024-50246-8. PMID: 38374083; PMCID: PMC10876521.

Levin & Buck

2026

Gardner ER, Kopf GS, Buck J, Levin LR. Targeting Soluble Adenylyl Cyclase for On-Demand Contraception. Physiology (Bethesda). 2026 Sep 1;41(5):0. doi: 10.1152/physiol.00009.2026. Epub 2026 Mar 17. PMID: 41843491; PMCID: PMC13078594.
Fischoeder J, Marathe JG, Anderson DJ, Levin LR, Buck J, Ritagliati C. Assessing efficacy of ADCY10 inhibitors in cervical mucus. Mol Hum Reprod. 2026 Apr 11;32(2):gaag035. doi: 10.1093/molehr/gaag035. PMID: 42241232; PMCID: PMC13275317.
Ritagliati C, Devine F, Buck J, Levin LR. Sustained soluble adenylyl cyclase (sAC)-generated cAMP is necessary and sufficient for hyperactivated motility in human sperm. Hum Reprod. 2026 Feb 1;41(2):185-194. doi: 10.1093/humrep/deaf225. PMID: 41247380; PMCID: PMC12864154.

2025

Ferreira J, Belliveau H, Levin LR, Buck J. Biochemical characterization of the full-length isoform of soluble adenylyl cyclase. J Biol Chem. 2025 Dec;301(12):110889. doi: 10.1016/j.jbc.2025.110889. Epub 2025 Nov 5. PMID: 41197733; PMCID: PMC12802110.
Violante S, Kyaw A, Kouatli L, Paladugu K, Apostolakis L, Jenks M, Johnson A, Sheldon RD, Whitten D, Schilmiller AL, Visconti PE, Cross JR, Levin LR, Buck J, Balbach M. Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase. Proc Natl Acad Sci U S A. 2025 Sep 30;122(39):e2506417122. doi: 10.1073/pnas.2506417122. Epub 2025 Sep 24. PMID: 40991431; PMCID: PMC12501146.
Ferreira J, Belliveau H, Steegborn C, Buck J, Levin LR. Updating the Mechanism of Bicarbonate (HCO3-) Activation of Soluble Adenylyl Cyclase (sAC). Int J Mol Sci. 2025 Jul 3;26(13):6401. doi: 10.3390/ijms26136401. PMID: 40650178; PMCID: PMC12250328.
Luque GM, Jabloñski M, Schiavi-Ehrenhaus LJ, Del Prado RC, Balbach M, Romarowski A, Martin-Hidalgo D, Visconti PE, Krapf D, Darszon A, Krapf D, Buck J, Levin LR, Buffone MG. Bovine serum albumin-induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation. J Physiol. 2025 May;603(9):2633-2653. doi: 10.1113/JP288389. Epub 2025 May 5. PMID: 40320899.
Violante S, Kyaw A, Kouatli L, Paladugu K, Apostolakis L, Jenks M, Johnson A, Sheldon RD, Schilmiller AL, Visconti PE, Cross JR, Levin LR, Buck J, Balbach M. Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase. bioRxiv [Preprint]. 2025 Apr 10:2025.04.09.647926. doi: 10.1101/2025.04.09.647926. Update in: Proc Natl Acad Sci U S A. 2025 Sep 30;122(39):e2506417122. doi: 10.1073/pnas.2506417122. PMID: 40291655; PMCID: PMC12027340.
Ayoub S, Rivera Sanchez NDR, Fischoeder J, Balbach M, Levin LR, Buck J, Ritagliati C. Cyclic AMP Rescue of Motility in Sperm Devoid of Soluble Adenylyl Cyclase. Int J Mol Sci. 2025 Feb 11;26(4):1489. doi: 10.3390/ijms26041489. PMID: 40003956; PMCID: PMC11855772.

2024

Visconti PE, Levin LR, Buck J. David Garbers and the Birth of cAMP Biology in Mammalian Sperm. Mol Reprod Dev. 2024 Oct;91(10):e23773. doi: 10.1002/mrd.23773. PMID: 39385557.
Sanchez NDRR, Ritagliati C, Kopf GS, Kretschmer S, Buck J, Levin LR. The uniqueness of on-demand male contraception. Mol Aspects Med. 2024 Jun;97:101281. doi: 10.1016/j.mam.2024.101281. Epub 2024 May 27. PMID: 38805792; PMCID: PMC11167369.
Sun S, Fushimi M, Rossetti T, Kaur N, Ferreira J, Miller M, Quast J, van den Heuvel J, Steegborn C, Levin LR, Buck J, Myers RW, Kargman S, Liverton N, Meinke PT, Huggins DJ. Addition to “Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation”. J Chem Inf Model. 2024 Feb 12;64(3):1106. doi: 10.1021/acs.jcim.4c00068. Epub 2024 Jan 23. Erratum for: J Chem Inf Model. 2023 May 8;63(9):2828-2841. doi: 10.1021/acs.jcim.2c01577. PMID: 38258980.

Lipkind

2026

Ackerman-Banks CM, Lipkind HS, Smith GN. Transitioning: From Pregnancy to Lifelong Cardiovascular Care. Clin Obstet Gynecol. 2026 Oct 30. doi: 10.1097/GRF.0000000000001059. Epub ahead of print. PMID: 42960407.
Kharbanda EO, Cao J, Vazquez-Benitez G, Ehresmann K, Seburg EM, DeSilva MB, Daida YG, Vesco KK, Sidebottom AC, Effros R, Lipkind HS, Palmsten K. COVID-19 Vaccination During Pregnancy or Lactation and Infant Growth and Health Care Utilization. Acad Pediatr. 2026 Sep 28;26(8):103477. doi: 10.1016/j.acap.2026.103477. Epub ahead of print. PMID: 42805288.
Figueroa EB, Vazquez-Benitez G, Ehresmann K, Seburg EM, Daida YG, Vesco KK, Sidebottom A, Lipkind HS, DeSilva MB, Cao J, Kharbanda EO, Palmsten K. COVID-19 vaccination in pregnancy and postpartum and human milk feeding non-initiation and discontinuation. Am J Epidemiol. 2026 Aug 5;195(8):2121-2130. doi: 10.1093/aje/kwag105. PMID: 42127308.
Heaps S, Staniczenko A, Garcia M, Sanchez E, Pardo C, Riley L, Lipkind HS, Son M. Perceptions of respiratory syncytial virus vaccination among a publicly insured pregnant cohort. Am J Obstet Gynecol MFM. 2026 Jul;8(7):101982. doi: 10.1016/j.ajogmf.2026.101982. Epub 2026 May 5. PMID: 42092526.
Ackerman-Banks CM, Palmsten K, Lipkind HS, Ahrens KA. Association of treatment for prenatal depression with cardiovascular disease within 24 months after delivery. Pregnancy (Hoboken). 2026 Jun 19;2(4):e70344. doi: 10.1002/pmf2.70344. PMID: 42596910; PMCID: PMC13344210.
DeSilva M, Haapala J, Kharbanda EO, Vesco KK, Daley MF, Getahun D, Raisler K, Naleway AL, Jackson LA, Williams JTB, Klein NP, Jacobson KB, Jorgensen S, Dixon BE, Fuller CC, Weintraub ES, Quincer EM, Lipkind HS, Vazquez-Benitez G. Association of Respiratory Syncytial Virus Vaccination During Pregnancy With Adverse Obstetric and Neonatal Outcomes. Obstet Gynecol. 2026 Jun 18. doi: 10.1097/AOG.0000000000006354. Epub ahead of print. PMID: 42314184.
Quincer EM, Vazquez-Benitez G, Weintraub ES, Walton K, Wang L, Vesco KK, Henninger ML, Daley MF, Hambidge SJ, Williams JTB, Donahue JG, Zerbo O, Getahun D, Jackson LA, Fuller CC, Lipkind HS, Naleway AL, McNeil MM, Kharbanda EO. Association Between COVID-19 Vaccination During Pregnancy and Safety Among Infants. J Pediatric Infect Dis Soc. 2026 Jun 12;15(6):piag036. doi: 10.1093/jpids/piag036. PMID: 42231558; PMCID: PMC13382912.
Staniczenko AP, Dean JR, Voegtline K, Thomas C, Abedian S, Sholle E, Yen S, Cron J, Osborne LM, Lipkind HS, Son M. Social Vulnerability Index and Its Association With Postpartum Care Attendance. Obstet Gynecol. 2026 May 1;147(5):e97-e105. doi: 10.1097/AOG.0000000000006129. Epub 2025 Nov 20. PMID: 41264920; PMCID: PMC13067376.
Nauman E, Tang JH, Lipkind HS, Hatch BA, Gross B, Weiner M, Shenkman EA. Characteristics of Pregnancy-related Health Events Across Care Settings Nationwide in PCORnet®. Med Care. 2026 Feb 1;64(2S Suppl 3):S251-S257. doi: 10.1097/MLR.0000000000002243. Epub 2026 Jan 8. PMID: 41504754; PMCID: PMC12783330.
Ireland E, Palmsten K, Lipkind HS, Ackerman-Banks CM, Ahrens KA. Characteristics and Incidence of Lactational Mastitis Using State-Wide Data from 2016 to 2022. J Womens Health (Larchmt). 2026 Jan;35(1):85-95. doi: 10.1177/15409996251380127. Epub 2025 Sep 23. PMID: 40985104.

2025

Ireland E, Palmsten K, Lipkind HS, Ackerman-Banks CM, Ahrens KA. Characteristics and Incidence of Lactational Mastitis Using State-Wide Data from 2016 to 2022. J Womens Health (Larchmt). 2025 Sep 23. doi: 10.1177/15409996251380127. Epub ahead of print. PMID: 40985104.
Sheth SS, Vazquez-Benitez G, DeSilva MB, Zhu J, Seburg EM, Denoble AE, Daley MF, Getahun D, Klein NP, Vesco KK, Irving SA, Nelson JC, Williams JTB, Hambidge SJ, Donahue JG, Lipkind HS, Kharbanda EO. Coronavirus Disease 2019 (COVID-19) Vaccination and Spontaneous Abortion. Obstet Gynecol. 2025 May 2;146(1):129-137. doi: 10.1097/AOG.0000000000005904. PMID: 40311142; PMCID: PMC12169859.
Ackerman-Banks CM, Spatz ES, Lipkind HS. One Step Closer to Unlocking Preeclampsia Prevention. J Am Coll Cardiol. 2025 Apr 15;85(14):1501-1503. doi: 10.1016/j.jacc.2025.03.455. PMID: 40204379.
Ahrens KA, Palmsten K, Lipkind HS, Ackerman-Banks CM. Prevalence of GLP-1 medication exposure prior to, during, and after pregnancy using state-wide data from 2017 to 2023. Am J Obstet Gynecol MFM. 2025 Feb;7(2):101596. doi: 10.1016/j.ajogmf.2024.101596. Epub 2025 Jan 2. PMID: 39755252; PMCID: PMC12230788.
Shanab BM, Gaffey AE, Schwamm L, Zawalich M, Sarpong DF, Pérez-Escamilla R, Dorney J, Cooperman C, Schafer R, Lipkind HS, Lu Y, Onuma OK, Spatz ES. Closing the Gap: Digital Innovations to Address Hypertension Disparities. Curr Cardiol Rep. 2025 Jan 15;27(1):23. doi: 10.1007/s11886-024-02171-x. PMID: 39812880.
Bebus SM, Palmsten K, Lipkind HS, Ackerman-Banks CM, Ahrens KA. Ambulatory care utilization in the first 24 months’ postpartum by rurality and pregnancy-related conditions: A prospective cohort study from Maine. J Rural Health. 2025 Jan;41(1):e12912. doi: 10.1111/jrh.12912. PMID: 39722432; PMCID: PMC12270079.

2024

Kaufman JS, Yonkers KA, Maltz C, Friedhoff CM, Londoño Tobon A, Mele A, Tessier-Kay M, Grechukhina O, Lipkind H, Byatt N, Forray A. Reporting Perinatal Substance Use to Child Protective Services: Obstetric Provider Perspectives on the Impact on Care. J Womens Health (Larchmt). 2024 Nov;33(11):1501-1508. doi: 10.1089/jwh.2023.0822. Epub 2024 May 21. PMID: 38770764.
Denoble AE, Vazquez-Benitez G, Sheth SS, Ackerman-Banks CM, DeSilva MB, Zhu J, Daley MF, Getahun D, Klein NP, Vesco KK, Irving SA, Nelson J, Williams JTB, Hambidge SJ, Donahue JG, Weintraub ES, Kharbanda EO, Lipkind HS. Coronavirus Disease 2019 (COVID-19) Vaccination and Stillbirth in the Vaccine Safety Datalink. Obstet Gynecol. 2024 Aug 1;144(2):215-222. doi: 10.1097/AOG.0000000000005632. Epub 2024 Jun 6. PMID: 38843526; PMCID: PMC11250101.
Kharbanda EO, DeSilva MB, Lipkind HS, Romitti PA, Zhu J, Vesco KK, Boyce TG, Daley MF, Fuller CC, Getahun D, Jackson LA, Williams JTB, Zerbo O, Weintraub ES, Vazquez-Benitez G. COVID-19 Vaccination in the First Trimester and Major Structural Birth Defects Among Live Births. JAMA Pediatr. 2024 Aug 1;178(8):823-829. doi: 10.1001/jamapediatrics.2024.1917. PMID: 38949821; PMCID: PMC11217887.
Ahrens KA, Palmsten K, Lipkind HS, Ackerman-Banks CM, Grantham CO. Does reversible postpartum contraception reduce the risk of pregnancy condition recurrence? A longitudinal claims-based study from Maine. Ann Epidemiol. 2024 Aug;96:58-65. doi: 10.1016/j.annepidem.2024.06.001. Epub 2024 Jun 15. PMID: 38885800; PMCID: PMC11283344.
Son M, Riley LE, Staniczenko AP, Cron J, Yen S, Thomas C, Sholle E, Osborne LM, Lipkind HS. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Netw Open. 2024 Jul 1;7(7):e2419268. doi: 10.1001/jamanetworkopen.2024.19268. PMID: 38976271; PMCID: PMC11231799.
Vesco KK, Denoble AE, Lipkind HS, Kharbanda EO, DeSilva MB, Daley MF, Getahun D, Zerbo O, Naleway AL, Jackson L, Williams JTB, Boyce TG, Fuller CC, Weintraub ES, Vazquez-Benitez G. Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstet Gynecol. 2024 Jun 1;143(6):794-802. doi: 10.1097/AOG.0000000000005583. Epub 2024 Apr 17. PMID: 38626447; PMCID: PMC11090513.
Ackerman-Banks CM, Palmsten K, Lipkind HS, Ahrens KA. Association between gestational diabetes and cardiovascular disease within 24 months postpartum. Am J Obstet Gynecol MFM. 2024 Jun;6(6):101366. doi: 10.1016/j.ajogmf.2024.101366. Epub 2024 Apr 3. PMID: 38580094.
Brooks N, Irving SA, Kauffman TL, Vesco KK, Slaughter M, Smith N, Tepper NK, Olson CK, Weintraub ES, Naleway AL; Vaccine Safety Datalink Menstrual Irregularities Working Group. Abnormal uterine bleeding diagnoses and care following COVID-19 vaccination. Am J Obstet Gynecol. 2024 May;230(5):540.e1-540.e13. doi: 10.1016/j.ajog.2024.01.006. Epub 2024 Jan 12. PMID: 38219855.
Weingarten SJ, Brockhoff EJ, Spielman E, Lipkind HS, Scholl JE. Implementation of virtual group prenatal genetic counseling: a pilot study. Am J Obstet Gynecol MFM. 2024 Apr;6(4):101327. doi: 10.1016/j.ajogmf.2024.101327. Epub 2024 Mar 4. PMID: 38447675.
Ahrens KA, Palmsten K, Grantham CO, Lipkind HS, Ackerman-Banks CM. Acute health care utilization in the first 24 months postpartum by rurality and pregnancy complications: A prospective cohort study. Health Serv Res. 2024 Feb;59(1):e14247. doi: 10.1111/1475-6773.14247. Epub 2023 Oct 12. PMID: 37827521; PMCID: PMC10771903.
Kauffman TL, Irving SA, Brooks N, Vesco KK, Slaughter M, Smith N, Tepper NK, Olson CK, Weintraub ES, Naleway AL; Vaccine Safety Datalink Menstrual Irregularities Workgroup. Postmenopausal bleeding after COVID-19 vaccination. Am J Obstet Gynecol. 2024 Jan;230(1):71.e1-71.e14. doi: 10.1016/j.ajog.2023.09.007. Epub 2023 Sep 17. PMID: 37726057.

Lujan

2026

Evans AT, Rehani E, Smith B, Hong MD, Lewin Z, Hiroshige K, Spandorfer SD, Hajirasouliha I, Lujan ME, Hoeger KM. Diagnosis of Polycystic Ovary Syndrome With Predictive Modeling of Select Clinical Features. O G Open. 2026 Mar 19;3(2):e161. doi: 10.1097/og9.0000000000000161. PMID: 41868592; PMCID: PMC13002152.
Zhang J, Kim JY, Levine R, Cho C, Lee H, Thoma E, Carter FE, Jarrett BY, Smith B, Vanden Brink H, Lujan ME. Impact of Polycystic Ovary Syndrome Status on Changes in Reproductive Function During a Hypocaloric Dietary Intervention. Nutrients. 2026 Feb 16;18(4):654. doi: 10.3390/nu18040654. PMID: 41754170; PMCID: PMC12943252.
Carter FE, Kalay AB, Jarrett BY, Oldfield AL, Brink HV, Lujan ME. Utility of Polycystic Ovarian Morphology on Ultrasonography Across Menstrual Cycle Phases to Aid in the Diagnosis of Polycystic Ovary Syndrome (PCOS). J Ultrasound Med. 2026 Jan;45(1):115-125. doi: 10.1002/jum.70040. Epub 2025 Aug 27. PMID: 40862524.

2025

Carter FE, Jarrett BY, Lee ND, Zaman N, Reich AM, Wilson KA, Oldfield AL, Vanden Brink H, Lujan ME. Changes in antral follicle dynamics following weight loss in women with polycystic ovary syndrome. Hum Reprod. 2025 Nov 1;40(11):2161-2171. doi: 10.1093/humrep/deaf169. PMID: 40929646; PMCID: PMC12584915.
Carter FE, Kalay AB, Jarrett BY, Oldfield AL, Brink HV, Lujan ME. Utility of Polycystic Ovarian Morphology on Ultrasonography Across Menstrual Cycle Phases to Aid in the Diagnosis of Polycystic Ovary Syndrome (PCOS). J Ultrasound Med. 2025 Aug 27. doi: 10.1002/jum.70040. Epub ahead of print. PMID: 40862524.
Carter FE, Jarrett BY, Oldfield AL, Vanden Brink H, Kim JY, Lujan ME. Impact of Hypocaloric Dietary Intervention on Phenotypic Presentations of Polycystic Ovary Syndrome (PCOS). Nutrients. 2025 Jul 4;17(13):2223. doi: 10.3390/nu17132223. PMID: 40647327; PMCID: PMC12251410.

Vanden Brink H, McCormick KC, Lujan ME, Chang J, Ipp L, Mudrak EL, Alladeen A, Lamar H, Kim JY, Mendle J. Psychological symptoms in perimenarcheal adolescents: association with PCOS risk factors. Front Endocrinol (Lausanne). 2025 Jun 12;16:1551958. doi: 10.3389/fendo.2025.1551958. PMID: 40575266; PMCID: PMC12197959.
Yano Maher JC, Zelinski MB, Oktay KH, Duncan FE, Segars JH, Lujan ME, Lou H, Yun BH, Hanfling SN, Schwartz LE, Laronda MM, Halvorson LM, O’Neill KE, Gomez-Lobo V. Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development – sponsored ovarian nomenclature workshop. Fertil Steril. 2025 May;123(5):761-778. doi: 10.1016/j.fertnstert.2024.11.016. Epub 2024 Nov 15. PMID: 39549739; PMCID: PMC12045743.
Peña AS, Witchel SF, Boivin J, Burgert TS, Ee C, Hoeger KM, Lujan ME, Mousa A, Oberfield S, Tay CT, Teede H. International evidence-based recommendations for polycystic ovary syndrome in adolescents. BMC Med. 2025 Mar 11;23(1):151. doi: 10.1186/s12916-025-03901-w. PMID: 40069730; PMCID: PMC11899933.
van der Ham K, Barbagallo F, van Schilfgaarde E, Lujan ME, Laven JSE, Louwers YV. The additional value of ultrasound markers in the diagnosis of polycystic ovary syndrome. Fertil Steril. 2025 Feb;123(2):342-349. doi: 10.1016/j.fertnstert.2024.08.342. Epub 2024 Aug 31. PMID: 39218282.

2024

van der Ham K, Barbagallo F, van Schilfgaarde E, Lujan ME, Laven JSE, Louwers YV. The additional value of ultrasound markers in the diagnosis of polycystic ovary syndrome. Fertil Steril. 2024 Aug 31:S0015-0282(24)01995-2. doi: 10.1016/j.fertnstert.2024.08.342. Epub ahead of print. PMID: 39218282.
Vanden Brink H, Burgert TS, Barral R, Malik A, Gadiraju M, Lujan ME. Ovarian Morphology in Girls Longitudinal Cohort Study: Pilot Evaluation of Ovarian Morphology as a Biomarker of Reproductive and Metabolic Features during the First Gynecological Year. J Pediatr Adolesc Gynecol. 2024 Jun;37(3):315-322. doi: 10.1016/j.jpag.2024.02.004. Epub 2024 Feb 21. PMID: 38395192; PMCID: PMC11195913.
Oldfield AL, Carter FE, Reeves RE, Jarrett BY, Vanden Brink H, Lujan ME. Impact of a hypocaloric dietary intervention on antral follicle dynamics in eumenorrheic women with obesity. Hum Reprod. 2024 Apr 3;39(4):801-811. doi: 10.1093/humrep/deae017. PMID: 38335228; PMCID: PMC10988108.
Maitin-Shepard M, Werner EF, Feig LA, Chavarro JE, Mumford SL, Wylie B, Rando OJ, Gaskins AJ, Sakkas D, Arora M, Kudesia R, Lujan ME, Braun J, Mozaffarian D. Food, nutrition, and fertility: from soil to fork. Am J Clin Nutr. 2024 Feb;119(2):578-589. doi: 10.1016/j.ajcnut.2023.12.005. Epub 2023 Dec 13. PMID: 38101699.
Pea J, Bryan J, Wan C, Oldfield AL, Ganga K, Carter FE, Johnson LM, Lujan ME. Ultrasonographic criteria in the diagnosis of polycystic ovary syndrome: a systematic review and diagnostic meta-analysis. Hum Reprod Update. 2024 Jan 3;30(1):109-130. doi: 10.1093/humupd/dmad027. PMID: 37804097; PMCID: PMC10762001.

Marongiu

2026

Yan Z, Li H, Huang Z, Zhou M, Wang WT, Jiang S, Zhang M, Martinez-Nunez E, Marongiu R, Sarva H, Okun MS, Zhou J, Su C, Wang F. Early Prediction of Parkinson’s Disease Progression by Integrating Research Cohort and Real-World Data Using Knowledge-Anchored Graph Learning. medRxiv [Preprint]. 2026 Jul 9:2026.07.07.26357483. doi: 10.64898/2026.07.07.26357483. PMID: 42465923; PMCID: PMC13370551.
Castagnola C, Marongiu R, Wan Y, Torres ERS, Fan L, Jang MW, Cui Q, Kim J, Ye P, Zhu J, Panichkina A, Fall AB, Norman K, Gao B, Foxe N, Wong MY, Zhu D, Bhagwat M, Gong S, Orr AG, Lee FS, Surmeier DJ, Kaplitt MG, Gan L. Microglial sTREM2 limits dyskinesia and acts on TrkB to support circuit plasticity. bioRxiv [Preprint]. 2026 May 7:2026.05.06.723382. doi: 10.64898/2026.05.06.723382. PMID: 42146496; PMCID: PMC13174672.
Marongiu R, Cordato D, Reiss AB. Editorial: Genetic underpinnings of Alzheimer’s and Parkinson’s: insights and innovations. Front Genet. 2026 Apr 21;17:1846361. doi: 10.3389/fgene.2026.1846361. PMID: 42088780; PMCID: PMC13138796.
Dautan D, Paslawski W, Montejo SG, Doyon DC, Brioschi VI, Marongiu R, Kaplitt MG, Chen R, Dawson VL, Zhang X, Dawson TM, Svenningsson P. Gut-initiated alpha synuclein fibrils drive parkinsonism phenotypes: temporal mapping of REM sleep behavior disorder-like and other non-motor symptoms. Transl Neurodegener. 2026 Mar 10;15(1):10. doi: 10.1186/s40035-026-00536-6. PMID: 41808195; PMCID: PMC12973632.
Dautan D, Camargo A, Branzell N, Brioschi VI, Doyon D, Covatta E, Marongiu R, Kaplitt M, Chergui K, Zhang X, Svenningsson P. Altered acetylcholine modulations and corticoaccumbal pathway in P11-linked social dysfunction. Mol Psychiatry. 2026 Mar;31(3):1785-1798. doi: 10.1038/s41380-025-03324-2. Epub 2025 Nov 3. PMID: 41184570; PMCID: PMC12916318.

2025

Marongiu R, Wang J, Unda SR, Barbera J, Velazquez L, Li R, Jimenez-Gonzalez M, Tower W, de Silva N, Retik R, Stanley SA, Kaplitt MG. Control of feeding behavior by modified retrograde AAV to the gastrointestinal tract nerve afferents. Sci Rep. 2025 Dec 14;16(1):1773. doi: 10.1038/s41598-025-31377-4. PMID: 41392163; PMCID: PMC12804985.
Leri M, Bertolini A, Diaz M, Marongiu R. Editorial: Estrogens and neurodegeneration: a link between menopause and Alzheimer’s disease in women. Front Mol Biosci. 2025 Nov 7;12:1727385. doi: 10.3389/fmolb.2025.1727385. PMID: 41280324; PMCID: PMC12635531.
Gregory S, Bridgeman K, Darwin H, Barbato M, Booi L, Serrat AB, Chadha AS, Farina FR, Jenkins N, Jutila OI, Low A, Marongiu R, Naci L, Pulford P, Ritchie CW, Ritchie K, Udeh-Momoh C, Watermeyer T, Welstead M, Muniz-Terrera G. Associations of estrogen with modifiable and non-modifiable risk factors for dementia: A narrative review. Alzheimers Dement. 2025 Nov;21(11):e70873. doi: 10.1002/alz.70873. PMID: 41263327; PMCID: PMC12631545.
Mostert CM, Udeh-Momoh C, Winkler AS, McLaughlin C, Eyre H, Salama M, Ranchod K, Trepel D, Vradenburg G, Hynes W, Fieggen G, Ali S, Mekkaoui NEL, Landay A, Bobrow K, Muyela L, Atkins K, Chadha AS, Marongiu R, Barbato M, Nightingale S, Joska J, Njamnshi AK, Rizig M, Kahn JG, Blackmon K, Merali Z, Ibanez A. Broadening dementia risk models: building on the 2024 Lancet Commission report for a more inclusive global framework. EBioMedicine. 2025 Oct;120:105950. doi: 10.1016/j.ebiom.2025.105950. Epub 2025 Sep 25. PMID: 41004922; PMCID: PMC12509747.
Trigiani L, Chernavsky N, Kim R, Hong N, Hawkins R, Le E, Bahninameh Z, Yamaguchi K, Bernard J, Huang A, Rivera D, Allan-Rahill N, Lamont M, Marongiu R, Iadecola C, Nishimura N, Schaffer C. Memory deficits in hypertensive ApoE4 mice reversed by P2Y12 inhibition via different mechanisms in males and perimenopausal females. Res Sq [Preprint]. 2025 Sep 26:rs.3.rs-7643285. doi: 10.21203/rs.3.rs-7643285/v1. PMID: 41041548; PMCID: PMC12486115.
Marongiu R, Platholi J, Park L, Yu F, Sommer G, Woods C, Milner TA, Glass MJ. Correction: Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease. Front Mol Biosci. 2025 Sep 1;12:1684511. doi: 10.3389/fmolb.2025.1684511. Erratum for: Front Mol Biosci. 2025 May 14;12:1597130. doi: 10.3389/fmolb.2025.1597130. PMID: 40958778; PMCID: PMC12434325.
Barbato M, Guzman B, Dixit S, Chadha AS, Marongiu R. A sex- and gender-informed future for Parkinson’s disease care. Clin Transl Med. 2025 Jun;15(6):e70382. doi: 10.1002/ctm2.70382. PMID: 40551585; PMCID: PMC12185897.
Marongiu R, Platholi J, Park L, Yu F, Sommer G, Woods C, Milner TA, Glass MJ. Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer’s disease. bioRxiv [Preprint]. 2025 Jun 5:2025.03.14.643317. doi: 10.1101/2025.03.14.643317. Update in: Front Mol Biosci. 2025 May 14;12:1597130. doi: 10.3389/fmolb.2025.1597130. PMID: 40161644; PMCID: PMC11952527.
Wichmann T, Nelson A, Torres ERS, Svenningsson P, Marongiu R. Leveraging animal models to understand non-motor symptoms of Parkinson’s disease. Neurobiol Dis. 2025 May;208:106848. doi: 10.1016/j.nbd.2025.106848. Epub 2025 Feb 27. PMID: 40023327.
Antoniazzi AM, Unda SR, Norman S, Pomeranz LE, Marongiu R, Stanley SA, Friedman JM, Kaplitt MG. Non-invasive in vivo bidirectional magnetogenetic modulation of pain circuits. bioRxiv [Preprint]. 2025 Mar 19:2025.03.18.644041. doi: 10.1101/2025.03.18.644041. PMID: 40166248; PMCID: PMC11957015.
Castro-Aldrete L, Huc M, Domingos J, Vaudano E, Klietz M, Trenkwalder C, Oosterbaan A, Flanagan R, Marongiu R, Santuccione-Chadha A. Using a sex- and gender-informed lens to enhance care in Parkinson’s disease. Nat Med. 2025 Feb;31(2):367-369. doi: 10.1038/s41591-024-03363-2. PMID: 39753966.
Moreno-Gonzalez I, Garcia-Martin J, Marongiu R. Editorial: Animal models of Alzheimer’s disease and other dementias: past, present, and future. Front Aging Neurosci. 2025 Jan 6;16:1539837. doi: 10.3389/fnagi.2024.1539837. PMID: 39834617; PMCID: PMC11743453.

2024

Unda SR, Pomeranz LE, Marongiu R, Yu X, Kelly L, Hassanzadeh G, Molina H, Vaisey G, Wang P, Dyke JP, Fung EK, Grosenick L, Zirkel R, Antoniazzi AM, Norman S, Liston CM, Schaffer C, Nishimura N, Stanley SA, Friedman JM, Kaplitt MG. Bidirectional regulation of motor circuits using magnetogenetic gene therapy. Sci Adv. 2024 Oct 11;10(41):eadp9150. doi: 10.1126/sciadv.adp9150. Epub 2024 Oct 9. PMID: 39383230; PMCID: PMC11463271.

Martin

2026

Taylor SN, Martin CR. The society for neonatal nutrition and lifelong health: Building science and translating research to inform neonatal nutritional care. Semin Perinatol. 2026 Aug;50(5):152277. doi: 10.1016/j.semperi.2026.152277. Epub 2026 Jun 27. PMID: 42364968.
Garg PM, Shenberger J, Martin CR, Neu J. “Necrotizing enterocolitis”: a paradigm shift. Pediatr Res. 2026 Jul 18:10.1038/s41390-026-05303-x. doi: 10.1038/s41390-026-05303-x. Epub ahead of print. PMID: 42471466; PMCID: PMC13479360.
Martin CR. The Role of Early Parenteral Amino Acid Supplementation in ELBW Infants on School-Age Outcomes. Pediatrics. 2026 Jul 1;158(1):e2026075931. doi: 10.1542/peds.2026-075931. PMID: 42242702.
Patel RM, Rose AT, Neves S, Giacinto R, Perez S, Kim J, Martin CR, Good M, Yanowitz T, Profit J, Scottoline B, Markel TA, Spruce M, Hair A, Underwood M, Quinn J, Rosito S, Pryor E, Vernon L, Mebane A, Green L, Umberger E, Canvasser J; NEC Society Patient-Centered Outcomes Research Leadership Team. Developing a prioritized research agenda for necrotizing enterocolitis. J Perinatol. 2026 Jul;46(7):1290-1299. doi: 10.1038/s41372-026-02771-1. Epub 2026 Jul 1. PMID: 42393375.
Fan H, Zheng Z, Oliphant K, Li J, Mack R, Ju CW, Trandai B, Tu J, Zhang FQ, Zhang R, Xie Z, Yin C, Cai C, Kennedy MS, McNeely T, Cham C, Shah H, Dong L, Su R, Martin CR, Layden BT, Hamanaka RB, Mutlu GM, Chang EB, Zhang J, Chi H, Claud EC, He C, Chen J. Maternal trans-vaccenic acid shapes neonatal T cell development and early-life immune imprinting. Science. 2026 Jun 18;392(6804):eaea4041. doi: 10.1126/science.aea4041. Epub 2026 Jun 18. PMID: 42313977; PMCID: PMC13621437.
Gertel ER, Ding VY, Phongpreecha T, Xie F, Parsons A, Marić I, Aghaeepour N, Sylvester KG, Chock VY, Kerner JA, Martin CR, Stevenson DK, Shaw GM, Reiss JD. Triglyceride profiles in preterm infants reveal dynamic and age-specific trajectories. Front Pediatr. 2026 Jun 12;14:1777798. doi: 10.3389/fped.2026.1777798. PMID: 42368277; PMCID: PMC13303854.
Vergales B, Scala M, Bruno C, Crabtree C, Gray M, Hoffman S, McLean C, O’Reilly D, Quinones Cardona V, Bergner EM, Brady JM, Johnston L, Myers P, Good M, McNamara PJ, DeMauro S, Loyd J, Maron J, Martin CR, McElroy SJ, Stroustrup A, Taylor SN, Tipple TE, Patel RM, Shah S, Song C, Davis A, Gupta M, Escobedo M, French H. Compressing neonatal-perinatal medicine fellowship training: a critical appraisal of the American Board of Pediatrics proposed 2-year pathway. J Perinatol. 2026 Jun;46(6):1112-1118. doi: 10.1038/s41372-026-02743-5. Epub 2026 Jun 3. PMID: 42236995; PMCID: PMC13290477.
Strobel KM, Martin CR. Current approaches to parenteral nutrition in preterm infants. Semin Perinatol. 2026 Jun;50(4):152237. doi: 10.1016/j.semperi.2026.152237. Epub 2026 Apr 26. PMID: 42045058.
Dyall SC, Brenna JT, Carlson SE, Crawford MA, Martin CR, Salem N Jr. Omega-3 and omega-6 polyunsaturated fatty acids in neurodevelopment and prematurity: Correcting imbalances and closing the Preterm PUFA Gap. Prog Lipid Res. 2026 Jun;101:101379. doi: 10.1016/j.plipres.2026.101379. Epub 2026 Feb 28. PMID: 41765236.
Garg PM, Bolisetty S, Martin CR, Premkumar MH. First, do no trend: aligning parenteral lipid therapy with physiology and evidence in neonates. Pediatr Res. 2026 Apr 20:10.1038/s41390-026-05019-y. doi: 10.1038/s41390-026-05019-y. Epub ahead of print. PMID: 42010157; PMCID: PMC13174074.
Weisoly DL, Brodsky D, Martin CR; Neonatal Insights 2025 Conference Organizing Committee; Weisoly DL, Saxonhouse M, Brodsky D, Honea S, Martin CR, Moore J, Patel RM, Ursprung R. Introduction. Semin Fetal Neonatal Med. 2026 Apr;31(2):101709. doi: 10.1016/j.siny.2026.101709. Epub 2026 Feb 28. PMID: 41832085.
Monthe-Dreze C, Bhushan B, Andrews C, Cherkerzian S, Perng W, Ahmed S, Baqui AH, Chowdhury N, Khanam R, Rahman S, Sheridan PA, Michelotti G, Martin CR, Lee AC, Sen S. Untargeted Metabolomics Analysis of Human Milk from Breastfeeding Bangladeshi Women Reveals Amino Acid Metabolic Pathways Associated with Maternal Nutritional Status and Infant Growth. J Nutr. 2026 Apr;156(4):101394. doi: 10.1016/j.tjnut.2026.101394. Epub 2026 Feb 4. PMID: 41651070; PMCID: PMC13084589.
Martin CR. Pooling the unpoolable in preterm fatty acid research. Arch Dis Child Fetal Neonatal Ed. 2026 Mar 3:fetalneonatal-2025-328568. doi: 10.1136/archdischild-2025-328568. Epub ahead of print. PMID: 41775514.
Kim ES, Lin MC, Lu CH, Casero D, Aguirre B, Brown J, Olagoke O, Martin CR, Wadehra M, Calkins KL, Chu A. Polyunsaturated Fatty Acid Balance Modulates Microglial State in a Murine Model of Oxygen-Induced Neovascularization. Nutrients. 2026 Feb 26;18(5):749. doi: 10.3390/nu18050749. PMID: 41829920; PMCID: PMC12986573.
Neu J, Del Moral T, Guthrie SO, Hudak ML, Indrio F, Kim JH, Kronström A, Martin CR, Modi N, Rastad J, Schnitzer TJ, Singh R, Strömberg S, Szajewska H, Thuresson M, Caplan M. Live biotherapeutic product IBP-9414 (L. reuteri) in very low birth weight infants: the Connection Study. Pediatr Res. 2026 Feb 20. doi: 10.1038/s41390-026-04826-7. Epub ahead of print. PMID: 41721054.

2025

German K, Wood TR, Gogcu S, Heagerty PJ, Mayock DE, Comstock BA, Puia-Dumitrescu M, Kolnik S, Mietzsch U, Law J, Perez K, Valentine G, Bammler TK, Juul SE; PENUT Trial Consortium. Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants. Pediatr Res. 2025 Dec;98(6):2186-2194. doi: 10.1038/s41390-025-04149-z. Epub 2025 Jun 2. PMID: 40456918.
Kim ES, Lin MC, Lu CH, Casero D, Aguirre B, Brown J, Olagoke O, Martin CR, Wadehra M, Calkins KL, Chu A. Polyunsaturated fatty acid balance modulates microglial state in a murine model of oxygen-induced neovascularization. Res Sq [Preprint]. 2025 Sep 23:rs.3.rs-7491382. doi: 10.21203/rs.3.rs-7491382/v1. PMID: 41041571; PMCID: PMC12486074.
Martin CR, Polin RA. The Unfinished Science of Preterm Nutrition: Implementing Progress and Navigating Uncertainty Belong in the Neonatal Intensive Care Unit. J Pediatr. 2025 Sep;284:114668. doi: 10.1016/j.jpeds.2025.114668. Epub 2025 May 22. PMID: 40412471.
Martin CR. Confronting the fatty acid problem in preterm infants: biological needs, nutritional gaps. Am J Clin Nutr. 2025 Aug;122(2):379-381. doi: 10.1016/j.ajcnut.2025.06.012. Epub 2025 Jul 4. PMID: 40615345.
Andrews C, Vodapally S, Foster LP, Lawandy I, Murphy M, Castellanos M, Moncada D, Mourao ML, Bhushan B, Berger PK, Fichorova R, Monthé-Drèze C, Freedman SD, Angelidou A, Martin CR, Sen S. Cohort profile: Mother and Infant Metabolome and Microbiome (MIMM) study, a prospective cohort study of mothers and infants in Boston, Massachusetts. BMJ Open. 2025 Jun 18;15(6):e096957. doi: 10.1136/bmjopen-2024-096957. PMID: 40533202; PMCID: PMC12182119.
German K, Wood TR, Gogcu S, Heagerty PJ, Mayock DE, Comstock BA, Puia-Dumitrescu M, Kolnik S, Mietzsch U, Law J, Perez K, Valentine G, Bammler TK, Juul SE; PENUT Trial Consortium. Neurodevelopmental outcomes after red cell transfusion exposure in male versus female extremely preterm infants. Pediatr Res. 2025 Jun 2. doi: 10.1038/s41390-025-04149-z. Epub ahead of print. PMID: 40456918.

Ten Barge JA, van den Bosch GE, Allegaert K, Bhatt A, Brindley N, Byrne D, Campbell-Yeo M, Camprubi-Camprubi M, Cavallaro G, Durrmeyer X, Embleton N, Eriksson M, Flint RB, Garrido F, Giannì ML, Giannoni E, Kitt H, Klerk D, Kristjánsdóttir G, Amponsah AK, Lapillonne A, Martin CR, Matyas M, Norman E, Ohja S, Pirlotte S, Del Rio R, Roué JM, Sevivas C, Slater R, Smits A, de Pipaon MS, Tauzin M, Ukkonen T, Unal S, Villamor E, Molloy EJ, Simons SHP. Pain management in preterm infants with necrotizing enterocolitis: an international expert consensus statement. Eur J Pediatr. 2025 May 14;184(6):342. doi: 10.1007/s00431-025-06168-8. PMID: 40369136; PMCID: PMC12078406.
Cohen AJ, Chidester WR, Wray DT, Jessen N, Jones A, Bitsui C, Zhao J, Maschek JA, Cox JE, Martin CR, Joss-Moore LA. Docosahexaenoic Acid Supplementation in Postnatal Growth Restricted Rats Does Not Normalize Lung Function or PPARγ Activity. Biomolecules. 2025 Apr 9;15(4):551. doi: 10.3390/biom15040551. PMID: 40305361; PMCID: PMC12024927.
Harpavat S, Aucott SW, Karpen SJ, Shneider BL, Wang K; and the SECTION ON GASTROENTEROLOGY, HEPATOLOGY, AND NUTRITION; COMMITTEE ON FETUS AND NEWBORN; SECTION ON SURGERY. Guidance for the Primary Care Provider in Identifying Infants With Biliary Atresia by 2-4 Weeks of Life: Clinical Report. Pediatrics. 2025 Feb 18:e2024070077. doi: 10.1542/peds.2024-070077. Epub ahead of print. PMID: 39961332.

2024

Bhutani VK, Wong RJ, Turkewitz D, Rauch DA, Mowitz ME, Barfield WD; COMMITTEE ON FETUS & NEWBORN. Phototherapy to Prevent Severe Neonatal Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation: Technical Report. Pediatrics. 2024 Sep 1;154(3):e2024068026. doi: 10.1542/peds.2024-068026. PMID: 39183672.
Sharma P, Luo G, Wang C, Brodsky D, Martin CR, Beam A, Beam K. Assessment of the clinical knowledge of ChatGPT-4 in neonatal-perinatal medicine: a comparative analysis with ChatGPT-3.5. J Perinatol. 2024 Sep;44(9):1365-1366. doi: 10.1038/s41372-024-01912-8. Epub 2024 Feb 24. PMID: 38402349.
Thomas J, Bunik M, Holmes A, Keels MA, Poindexter B, Meyer A, Gilliland A; SECTION ON BREASTFEEDING; SECTION ON ORAL HEALTH; COUNCIL ON QUALITY IMPROVEMENT AND PATIENT SAFETY; COMMITTEE ON FETUS & NEWBORN; SECTION ON OTOLARYNGOLOGY-HEAD AND NECK SURGERY. Identification and Management of Ankyloglossia and Its Effect on Breastfeeding in Infants: Clinical Report. Pediatrics. 2024 Aug 1;154(2):e2024067605. doi: 10.1542/peds.2024-067605. PMID: 39069819.
Buck CO, Santoro KL, Shabanova V, Martin CR, Taylor SN. Establishing feasibility and reliability of subcutaneous fat measurements by ultrasound in very preterm infants. Pediatr Res. 2024 Jul 28. doi: 10.1038/s41390-024-03439-2. Epub ahead of print. PMID: 39069538.
Ahmed S, Odumade OA, van Zalm P, Fatou B, Hansen R, Martin CR, Angelidou A, Steen H. Proteomics-Based Mapping of Bronchopulmonary Dysplasia-Associated Changes in Noninvasively Accessible Oral Secretions. J Pediatr. 2024 Jul;270:113774. doi: 10.1016/j.jpeds.2023.113774. Epub 2023 Oct 13. PMID: 37839510; PMCID: PMC11014893.
Holzapfel LF, Unger JP, Gordon P, Yang H, Cluette-Brown JE, Gollins LA, Hair AB, Martin CR. Fatty acid concentrations in preterm infants fed the exclusive human milk diet: a prospective cohort study. J Perinatol. 2024 May;44(5):680-686. doi: 10.1038/s41372-023-01841-y. Epub 2023 Dec 11. PMID: 38082071; PMCID: PMC11090710.
Sizemore N, Oliphant K, Zheng R, Martin CR, Claud EC, Chattopadhyay I. A digital twin of the infant microbiome to predict neurodevelopmental deficits. Sci Adv. 2024 Apr 12;10(15):eadj0400. doi: 10.1126/sciadv.adj0400. Epub 2024 Apr 10. PMID: 38598636; PMCID: PMC11006218.
Hingorani SR, Schmicker RH, Halloran B, Brophy P, Heagerty PJ, Juul S, Goldstein SL, Askenazi D; PENUT Investigators. Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates. Am J Kidney Dis. 2024 Apr;83(4):497-507. doi: 10.1053/j.ajkd.2023.09.008. Epub 2023 Nov 4. PMID: 37926336; PMCID: PMC10960703.
How HS, Malhotra A, Martin C. EBNEO commentary: Early human milk fortification in infants born extremely preterm: A randomised trial. Acta Paediatr. 2024 Mar;113(3):625-626. doi: 10.1111/apa.17110. Epub 2024 Jan 18. PMID: 38235608.
Nair J, Martin CR. Context of time on intestinal injury in preterm infants. Pediatr Res. 2024 Mar;95(4):873-874. doi: 10.1038/s41390-023-02844-3. Epub 2023 Oct 24. PMID: 37875727.

McKenney

2025

Tian W, McKenney AS, Zhan C. Facilitating Personalized Immunotherapy with Interventional Radiology and Tumor Organoids. J Vasc Interv Radiol. 2025 Dec;36(12):1851-1855. doi: 10.1016/j.jvir.2025.08.038. Review. PubMed PMID: 41276362; PubMed Central PMCID: PMC13519915.
Elhakim TS, Smolinski-Zhao S, Miyasato D, Lee V, Mansur A, Puello M, Mercaldo N, McKenney AS, Kalva SP, Dezube M, Daye D. Disparities in Utilization of Uterine Fibroid Embolization. JAMA Netw Open. 2025 Sep 2;8(9):e2532100. doi: 10.1001/jamanetworkopen.2025.32100. PubMed PMID: 40956582; PubMed Central PMCID: PMC12441870.
Talenfeld AD, Peng R, McKenney AS, Cobb B, Chughtai KA, Kierans AS, Guniganti P, Song C, Soliman MM, Pan S, Wu A, RoyChoudhury A, May BJ, Currie BM, Malhotra A, Browne WF, Charalel RA, Panarelli NC, Lee KS. Segmental Yttrium-90 Radioembolization with Day-of-Calibration Resin Microspheres: Durable Transarterial Ablation for Solitary Hepatocellular Carcinoma. Cardiovasc Intervent Radiol. 2025 Sep;48(9):1289-1298. doi: 10.1007/s00270-025-04130-7. Epub 2025 Aug 14. PubMed PMID: 40813475.
McKenney AS, Alexander ES, Zhao K, Ziv E, Solomon SB, Sofocleous CT, Sotirchos VS. Minimally Invasive Interventions in the Thorax for Tumor Treatment and Palliation. Radiographics. 2025 Jul;45(7):e240116. doi: 10.1148/rg.240116. Review. PubMed PMID: 40569835; NIHMSID:NIHMS2137260.
Minawala R, Kim M, Delau O, Ghiasian G, McKenney AS, Da Luz Moreira A, Chodosh J, McAdams-DeMarco M, Segev DL, Adhikari S, Dodson J, Shaukat A, Dane B, Faye AS. Sarcopenia Is a Risk Factor for Postoperative Complications Among Older Adults With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2025 Jun 13;31(6):1537-1547. doi: 10.1093/ibd/izae187. PubMed PMID: 39177976; PubMed Central PMCID: PMC13030995.
McKenney AS, Shulman L, Dominguez M, Evans M, Lasso A, Chauhan AS, Milsom JW, Sedrakyan A, Pua BB. Single session segmentation and live registration for augmented reality image guidance of cryoneurolysis. Clin Imaging. 2025 May;121:110440. doi: 10.1016/j.clinimag.2025.110440. Epub 2025 Mar 4. PubMed PMID: 40187153.
McKenney AS, Wu X, Yu Q, Gaba RC. Engaging IR Trainees in the Academic Publishing Editorial Process. J Vasc Interv Radiol. 2025 Mar;36(3):407-408. doi: 10.1016/j.jvir.2024.11.001. Epub 2024 Nov 10. PubMed PMID: 39532153.

Murphy, Kristin

2025

Park BJ, Hua S, Casler KD, Cefaloni E, Ayers MC, Lake RF, Murphy KE, Vertino PM, O’Connell MR, Murphy PJ. CUT&Tag overcomes biases of ChIP and establishes chromatin patterns for repetitive genomic loci. iScience. 2025 Nov 21;28(11):113757. doi: 10.1016/j.isci.2025.113757. eCollection 2025 Nov 21. PubMed PMID: 41234774; PubMed Central PMCID: PMC12605858.
McGrath KE, Olsen JL, Koniski AD, Murphy KE, Getman M, An HH, Schulz VP, Kim AR, Zhang B, Carlson TL, Papoin J, Blanc L, Kingsley PD, Westhoff CM, Gallagher PG, Chou ST, Steiner LA, Palis J. BMI1 regulates human erythroid self-renewal through both gene repression and gene activation. Nat Commun. 2025 Aug 15;16(1):7619. doi: 10.1038/s41467-025-62993-3. PubMed PMID: 40817093; PubMed Central PMCID: PMC12356964.
Murphy K, Getman M, Lv X, Murphy Z, Abid D, Rahman N, Bulger M, Steiner L. Histone H4 lysine 20 methylation marks genes dynamically regulated during erythroid maturation. Epigenetics Chromatin. 2025 Jul 26;18(1):48. doi: 10.1186/s13072-025-00609-2. PubMed PMID: 40713835; PubMed Central PMCID: PMC12296644.
Abid D, Murphy K, Murphy Z, Rahman N, Getman M, Steiner L. The Condensin II complex regulates essential gene expression programs during erythropoiesis. Development. 2025 May 15;152(10). doi: 10.1242/dev.204485. Epub 2025 May 19. PubMed PMID: 40260585; PubMed Central PMCID: PMC12148035

Murphy, Patrick

2027

Meng FW, Nguyen DK, Murphy PJ. Genomic Profiling of Chromatin State Using CUT&Tag. Methods Mol Biol. 2027;3074:275-284. doi: 10.1007/978-1-0716-5539-9_16. PubMed PMID: 42734756

2026

Hategan LA, Luo JQ, Creighton SD, Pirri F, McLean TAB, Hua S, Dahi TA, Jin Z, Winston SM, Reeves IL, Johnston K, Fahnestock M, Brimble MA, Walters BJ, Murphy PJ, Zovkic IB. The histone variant H2A.Z regulates sex differences in Alzheimer’s disease pathophysiology. Neuron. 2026 Oct 12;. doi: 10.1016/j.neuron.2026.09.019. [Epub ahead of print] PubMed PMID: 42863472.
Hua S, Sadi MA, Park BJ, Murphy PJ. A step-by-step guide for isolating soluble and insoluble chromatin followed by next-generation sequencing library preparation. STAR Protoc. 2026 Jul 9;7(3):104700. doi: 10.1016/j.xpro.2026.104700. [Epub ahead of print] PubMed PMID: 42424146; PubMed Central PMCID: PMC13380707.
Murphy P, Hua S, Reger N, Sokolova V, Huang K, Haseley M, Parker M, Casler K, Tan D, Wagner E. Cooperative and Opposing Functions of ANP32E and VPS72 Govern Gene Promoter Chromatin Status. Res Sq. 2026 Jan 30;. doi: 10.21203/rs.3.rs-8398559/v1. PubMed PMID: 41646306; PubMed Central PMCID: PMC12869565.

2025

Meng FW, Murphy PJ. Canonical and Variant Nucleosome Reprogramming from Sperm to Blastula. Methods Mol Biol. 2025;2923:17-32. doi: 10.1007/978-1-0716-4522-2_2. PubMed PMID: 40418441.
Wei X, Naidu V, Schneider P, Murphy PJ, Meng FW. Protocol for mapping insertion sites of Tol2 transgenes in zebrafish using TransTag. STAR Protoc. 2025 Dec 19;6(4):104259. doi: 10.1016/j.xpro.2025.104259. Epub 2025 Dec 5. PubMed PMID: 41351839; PubMed Central PMCID: PMC12721255.
Park BJ, Hua S, Casler KD, Cefaloni E, Ayers MC, Lake RF, Murphy KE, Vertino PM, O’Connell MR, Murphy PJ. CUT&Tag overcomes biases of ChIP and establishes chromatin patterns for repetitive genomic loci. iScience. 2025 Nov 21;28(11):113757. doi: 10.1016/j.isci.2025.113757. eCollection 2025 Nov 21. PubMed PMID: 41234774; PubMed Central PMCID: PMC12605858.
Meng FW, Schneider P, Wei X, Ariyasiri K, Halpern ME, Murphy PJ. TransTag enables simple and efficient transgene mapping in zebrafish via tagmentation. Cell Rep Methods. 2025 Jul 21;5(7):101090. doi: 10.1016/j.crmeth.2025.101090. Epub 2025 Jul 8. PubMed PMID: 40633543; PubMed Central PMCID: PMC12296462
Blanc RS, Shah N, Hachmer S, Salama NAS, Meng FW, Mousaei A, Puri G, Hwang JH, Wacker EE, Yang BA, Aguilar CA, Chakkalakal JV, Onukwufor JO, Murphy PJ, Calvi LM, Dilworth FJ, Dirksen RT. Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis. Nat Aging. 2025 Aug;5(8):1491-1509. doi: 10.1038/s43587-025-00902-5. Epub 2025 Jun 30. PubMed PMID: 40588650; PubMed Central PMCID: PMC12350153.
Park BJ, Hua S, Casler KD, Cefaloni E, Ayers MC, Lake RF, Murphy KE, Vertino PM, O’Connell MR, Murphy PJ. CUT&Tag Identifies Repetitive Genomic Loci that are Excluded from ChIP Assays. bioRxiv. 2025 Feb 5;. doi: 10.1101/2025.02.03.636299. PubMed PMID: 39974916; PubMed Central PMCID: PMC11838576.

2024

Das D, Khor ES, Jiang F, He J, Kawakami Y, Wainwright L, Hollinger J, Geiger J, Liu H, Meng F, Porter GA Jr, Jin Z, Murphy P, Yao P. Loss-of-function of RNA-binding protein PRRC2B causes translational defects and congenital cardiovascular malformation. medRxiv. 2024 Sep 27;. doi: 10.1101/2024.09.26.24313895. PubMed PMID: 39398999; PubMed Central PMCID: PMC11469349.
Reda A, Hategan LA, McLean TAB, Creighton SD, Luo JQ, Chen SES, Hua S, Winston S, Reeves I, Padmanabhan A, Dahi TA, Ramzan F, Brimble MA, Murphy PJ, Walters BJ, Stefanelli G, Zovkic IB. Role of the histone variant H2A.Z.1 in memory, transcription, and alternative splicing is mediated by lysine modification. Neuropsychopharmacology. 2024 Jul;49(8):1285-1295. doi: 10.1038/s41386-024-01817-2. Epub 2024 Feb 16. PubMed PMID: 38366138; PubMed Central PMCID: PMC11224360.
Duong P, Rodriguez-Parks A, Kang J, Murphy PJ. CUT&Tag applied to zebrafish adult tail fins reveals a return of embryonic H3K4me3 patterns during regeneration. Epigenetics Chromatin. 2024 Jul 20;17(1):22. doi: 10.1186/s13072-024-00547-5. PubMed PMID: 39033118; PubMed Central PMCID: PMC11264793.
Alexander WB, Wang W, Hill MA, O’Dell MR, Ruffolo LI, Guo B, Jackson KM, Ullman N, Friedland SC, McCall MN, Patel A, Figueroa-Guilliani N, Georger M, Belt BA, Whitney-Miller CL, Linehan DC, Murphy PJ, Hezel AF. Smad4 restricts injury-provoked biliary proliferation and carcinogenesis. Dis Model Mech. 2024 Jun 1;17(6). doi: 10.1242/dmm.050358. Epub 2024 Feb 28. PubMed PMID: 38415925; PubMed Central PMCID: PMC10924230.
Duong P, Rodriguez-Parks A, Kang J, Murphy PJ. CUT&Tag Applied to Zebrafish Adult Tail Fins Reveals a Return of Embryonic H3K4me3 Patterns During Regeneration. Res Sq. 2024 Apr 3;. doi: 10.21203/rs.3.rs-4189493/v1. PubMed PMID: 38645155; PubMed Central PMCID: PMC11030498.
Halblander FN, Meng FW, Murphy PJ. Anp32e protects against accumulation of H2A.Z at Sox motif containing promoters during zebrafish gastrulation. Dev Biol. 2024 Mar;507:34-43. doi: 10.1016/j.ydbio.2023.12.010. Epub 2023 Dec 28. PubMed PMID: 38159623; PubMed Central PMCID: PMC10922954.
Blanc RS, Shah N, Salama NAS, Meng FW, Mousaei A, Yang BA, Aguilar CA, Chakkalakal JV, Onukwufor JO, Murphy PJ, Calvi L, Dirksen R. Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis. Res Sq. 2024 Mar 15;. doi: 10.21203/rs.3.rs-3937628/v2. PubMed PMID: 38410478; PubMed Central PMCID: PMC10896381.

Nikitin

2026

Pirtz MG, Flesken-Nikitin A, Ralston CQ, Phuong DJ, Wang N, Chu T, Chen S, Zheng Y, Schmoeckel E, Yemelyanova A, Shih IM, Danko CG, Cosgrove BD, Nikitin AY. Cross-species analysis links cell-cell communication rewiring to NOTCH2 during serous endometrial carcinogenesis. bioRxiv [Preprint]. 2026 Sep 20:2026.09.01.748540. doi: 10.64898/2026.09.01.748540. PMID: 42779706; PMCID: PMC13596177.
Schutrum BE, Deng J, Kim JH, Gao A, Hur E, Crowley JC, Ling L, Pirtz MG, Ralston CQ, Nikitin AY, Fischbach C. Shape factor analysis as a quantitative framework for assessing spheroid and organoid morphology and invasiveness. APL Bioeng. 2026 Jul 1;10(3):036101. doi: 10.1063/5.0333152. PMID: 42389052; PMCID: PMC13322776.
Phuong DJ, Ralston CQ, Ezzat TM, Ashe CS, Armstrong AP, Flesken-Nikitin A, Yamulla RJ, Nikitin AY, Schimenti JC. Multiplex organoid mutagenesis reveals gene combinations driving transformation, pathology, and chemosensitivity in ovarian carcinoma. Genetics. 2026 Jun 3;233(2):iyag098. doi: 10.1093/genetics/iyag098. PMID: 41986871.
Schutrum BE, Deng J, Kim JH, Gao A, Hur E, Crowley JC, Ling L, Pirtz MG, Ralston CQ, Nikitin AY, Fischbach C. Shape Factor Analysis as a Quantitative Framework for Assessing Spheroid and Organoid Morphology and Invasiveness. bioRxiv [Preprint]. 2026 Mar 12:2026.03.10.710632. doi: 10.64898/2026.03.10.710632. Update in: APL Bioeng. 2026 Jul 01;10(3):036101. doi: 10.1063/5.0333152. PMID: 41959082; PMCID: PMC13060997.
Bidarimath M, Ralston CQ, Bidarimath N, Rose IM, Colina D, Schmoeckel E, Godwin AK, Mayr D, Ellenson LH, Flesken-Nikitin A, Nikitin AY. Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma. bioRxiv [Preprint]. 2026 Jan 30:2026.01.28.702332. doi: 10.64898/2026.01.28.702332. Update in: Cancer Heterog Plast. 2026;3(2):0005. doi: 10.47248/chp2603020005. PMID: 41659439; PMCID: PMC12873940.
Bidarimath M, Ralston CQ, Bidarimath N, Rose IM, Colina D, Schmoeckel E, Godwin AK, Mayr D, Ellenson LH, Flesken-Nikitin A, Nikitin AY. Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma. Cancer Heterog Plast. 2026;3(2):0005. doi: 10.47248/chp2603020005. Epub 2026 Apr 25. PMID: 42111394; PMCID: PMC13155427.

2025

Flesken-Nikitin A, Pirtz MG, Ashe CS, Ellenson LH, Yemelyanova A, Cosgrove BD, Nikitin AY. Cell state dynamics during early stages of serous endometrial carcinoma. J Pathol. 2025 Nov;267(3):289-303. doi: 10.1002/path.6470. Epub 2025 Sep 9. PMID: 40923619.
Phuong DJ, Ralston CQ, Ezzat TM, Ashe CS, Armstrong AP, Flesken-Nikitin A, Yamulla RJ, Nikitin AY, Schimenti JC. Combinatorial organoid mutagenesis screen reveals gene constellations driving malignant transformation, pathology and chemosensitivity in high-grade serous ovarian carcinoma. bioRxiv [Preprint]. 2025 May 11:2025.03.10.642422. doi: 10.1101/2025.03.10.642422. PMID: 40654781; PMCID: PMC12248148.
Phuong DJ, Pirtz MG, Ralston CQ, Cosgrove BD, Schimenti JC, Flesken-Nikitin A, Nikitin AY. Aggressive Serous Carcinomas of the Female Reproductive Tract: Cancer-Prone Cell States and Genetic Drivers. Cancers (Basel). 2025 Feb 11;17(4):604. doi: 10.3390/cancers17040604. PMID: 40002199; PMCID: PMC11852459.

2024

Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Author Correction: Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Nov 20;15(1):10053. doi: 10.1038/s41467-024-54465-x. Erratum for: Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39567528; PMCID: PMC11579345.
Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39366996; PMCID: PMC11452611.

Nishimura

2026

Bracko O, Reeson P, Erdener ŞE, Nishimura N, Boas DA, Brown CE, Schaffer CB. Stalled Capillary Blood Flow in the Brain: New Measurement Tools Unveil a Critical Role in Neurological Diseases. Annu Rev Physiol. 2026 Nov 4. doi: 10.1146/annurev-physiol-040425-104324. Epub ahead of print. PMID: 42981477.
Park JT, Timilsina S, Harman RC, Eom CY, Oh J, Fang Q, Nishimura N, Schaffer CB, Spring BQ. Far-field bioluminescent immune cell-mediated photodynamic therapy is limited by photon flux. Photochem Photobiol. 2026 Sep 22. doi: 10.1111/php.70149. Epub ahead of print. PMID: 42773702.
Knode BK, Beeghly GF, Schutrum BE, Wang D, Zheng Y, Battistella A, Goswami R, Eom CY, Kopyeva I, Bozec A, Guck J, Nishimura N, Girardo S, O’Hern CS, Fischbach C. Adipose-mimetic granular hydrogels uncover biophysical cues driving breast cancer invasion. Cell Biomater. 2026 Aug 18;2(8):100411. doi: 10.1016/j.celbio.2026.100411. Epub 2026 Mar 3. PMID: 42746462; PMCID: PMC13577451.
Yeh CW, Loh CA, Trigiani LJ, Chu N, Liu CH, Nieh MP, Nishimura N, Schaffer CB, Wang Y. Stable, micron-scale lipocondensates achieving prolonged circulation without PEGlyated lipids. Biomater Sci. 2026 Aug 11;14(16):4305-4316. doi: 10.1039/d6bm00335d. PMID: 42405635.
Gu W, Luozhong S, Cai S, Londhe K, Elkasri N, Hawkins R, Yuan Z, Su-Greene K, Yin Y, Cruz M, Chang YW, McMullen P, Wu C, Seo C, Guru A, Gao W, Sarmiento T, Schaffer C, Nishimura N, Cerione R, Yu Q, Warden M, Langer R, Jiang S. Author Correction: Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons. Nat Biomed Eng. 2026 Jun;10(6):1263. doi: 10.1038/s41551-026-01721-8. Erratum for: Nat Biomed Eng. 2024 Apr;8(4):415-426. doi: 10.1038/s41551-023-01150-x. PMID: 42204291.
Zirkel RT, Isaacson M, Liao C, Yi M, Yamaguchi K, Rivera D, Kuceyeski A, Nishimura N, Kwan AC, Schaffer CB. Psilocybin Prolongs the Neurovascular Coupling Response in Mouse Visual Cortex. bioRxiv [Preprint]. 2026 Mar 25:2025.07.25.666803. doi: 10.1101/2025.07.25.666803. PMID: 40766642; PMCID: PMC12324220.
Chernavsky NE, Hong N, Trigiani LJ, Nishimura N, Schaffer CB. Label-free tracking of subcortical white matter degradation in vivo using third harmonic generation microscopy in a mouse model of multiple sclerosis. Biomed Opt Express. 2026 Jan 29;17(2):1011-1028. doi: 10.1364/BOE.576538. PMID: 41693900; PMCID: PMC12904527.

2025

Tang RP, Kelley S, Küreli G, Long EA, Bressan PR, Shah S, Erdener ŞE, Jiang J, Giblin JT, Kura S, Simkulet MG, Rauscher BC, Schaffer CB, Nishimura N, Thunemann M, Devor A, Boas DA. Capillaries susceptible to frequent stall dynamics revealed by comparing OCT and bessel-2PM measurements. J Cereb Blood Flow Metab. 2025 Oct;45(10):1905-1917. doi: 10.1177/0271678X251353141. Epub 2025 Jun 25. PMID: 40562716; PMCID: PMC12202391.
Knode BK, Beeghly GF, Schutrum BE, Wang D, Zheng Y, Battistella A, Goswami R, Eom CY, Bozec A, Guck J, Nishimura N, Girardo S, O’Hern CS, Fischbach C. Adipose-mimetic granular hydrogels uncover biophysical cues driving breast cancer invasion. bioRxiv [Preprint]. 2025 Oct 24:2025.10.23.684224. doi: 10.1101/2025.10.23.684224. PMID: 41278796; PMCID: PMC12633341.

Trigiani L, Chernavsky N, Kim R, Hong N, Hawkins R, Le E, Bahninameh Z, Yamaguchi K, Bernard J, Huang A, Rivera D, Allan-Rahill N, Lamont M, Marongiu R, Iadecola C, Nishimura N, Schaffer C. Memory deficits in hypertensive ApoE4 mice reversed by P2Y12 inhibition via different mechanisms in males and perimenopausal females. Res Sq [Preprint]. 2025 Sep 26:rs.3.rs-7643285. doi: 10.21203/rs.3.rs-7643285/v1. PMID: 41041548; PMCID: PMC12486115.
Tian X, Zhang Y, Du H, Huang W, Bizimana LA, Nishimura N, Ai HW. An Enhanced Red Bioluminescent Indicator for Responsive Detection of Physiological Calcium Dynamics in Cells and Mice. ACS Sens. 2025 Aug 22;10(8):5826-5833. doi: 10.1021/acssensors.5c01093. Epub 2025 Jul 29. PMID: 40728872; PMCID: PMC12351538.
Yamaguchi A, Ma X, Uemura M, Tanida K, Nishimura N, Tan J, Nakagami G, Sanada H, Su D, Sarosiek K, Fujino H, Maeshige N. Non-Invasive Ultrasound Treatment Enhances the Release of Skeletal Muscle-Derived Extracellular Vesicles in Mice. FASEB J. 2025 Jul 15;39(13):e70787. doi: 10.1096/fj.202501797R. PMID: 40630003.
Kwon J, Huang X, Lee J, Kim J, Biswas P, Kim K, Eom CY, Nishimura N, Tian Z. Biodegradable PLGA Particles with Confined Water for Safe Photothermal Biomodulation. ACS Nano. 2025 Jun 3;19(21):20225-20236. doi: 10.1021/acsnano.5c06276. Epub 2025 May 23. PMID: 40406872.
Bauer AQ, Nishimura N, Iordanova B. Introduction to the Special Issue “Understanding Brain Disease with Live Imaging”. Neurophotonics. 2025 Jan;12(Suppl 1):S14601. doi: 10.1117/1.NPh.12.S1.S14601. Epub 2025 Aug 29. PMID: 40894081; PMCID: PMC12395498.

2024

Devor A, Abdalmalak A, Akkin T, Aponte Y, Augustine GJ, Brigadoi S, Buckley EM, Campbell RE, Carp SA, Chatton JY, Chen JL, Cheng JX, Cižmár T, Cooper RJ, Dan I, Drew PJ, Durduran T, Emiliani V, Fellin T, Foust AJ, Fu L, Gandjbakhche A, Gervain J, Gilad A, Codina EG, Han X, Hillman EM, Hochgeschwender U, Hu S, Ji N, Kara P, Kim BM, Ko TS, Kuzum D, Lecoq J, Mesquita RC, Murphy TH, Nägerl UV, Nishimura N, Ono Y, Ozana N, Pavone FS, Peterka DS, Pisanello F, Roe AW, Shih AY, Shoham S, St-Pierre F, Tak S, Tian L, Wang K, Wolf M, Yi J, Yizhar O, Yucel MA. On the Power of Constructive Criticism. Neurophotonics. 2024 Oct;11(4):040101. doi: 10.1117/1.NPh.11.4.040101. Epub 2024 Dec 20. PMID: 39713177; PMCID: PMC11661393.
Unda SR, Pomeranz LE, Marongiu R, Yu X, Kelly L, Hassanzadeh G, Molina H, Vaisey G, Wang P, Dyke JP, Fung EK, Grosenick L, Zirkel R, Antoniazzi AM, Norman S, Liston CM, Schaffer C, Nishimura N, Stanley SA, Friedman JM, Kaplitt MG. Bidirectional regulation of motor circuits using magnetogenetic gene therapy. Sci Adv. 2024 Oct 11;10(41):eadp9150. doi: 10.1126/sciadv.adp9150. Epub 2024 Oct 9. PMID: 39383230; PMCID: PMC11463271.
Lieberman S, Rivera DA, Morton R, Hingorani A, Southard TL, Johnson L, Reukauf J, Radwanski RE, Zhao M, Nishimura N, Bracko O, Schwartz TH, Schaffer CB. Circumscribing Laser Cuts Attenuate Seizure Propagation in a Mouse Model of Focal Epilepsy. Adv Sci (Weinh). 2024 Aug;11(29):e2300747. doi: 10.1002/advs.202300747. Epub 2024 May 29. PMID: 38810146; PMCID: PMC11304327.
Yslas AR, Park R, Nishimura N, Lee E. Monomeric and oligomeric amyloid-β cause distinct Alzheimer’s disease pathophysiological characteristics in astrocytes in human glymphatics-on-chip models. Lab Chip. 2024 Aug 6;24(16):3826-3839. doi: 10.1039/d4lc00287c. PMID: 39037244; PMCID: PMC11302770.
Gu W, Luozhong S, Cai S, Londhe K, Elkasri N, Hawkins R, Yuan Z, Su-Greene K, Yin Y, Cruz M, Chang YW, McMullen P, Wu C, Seo C, Guru A, Gao W, Sarmiento T, Schaffer C, Nishimura N, Cerione R, Yu Q, Warden M, Langer R, Jiang S. Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons. Nat Biomed Eng. 2024 Apr;8(4):415-426. doi: 10.1038/s41551-023-01150-x. Epub 2024 Feb 19. Erratum in: Nat Biomed Eng. 2026 May 27. doi: 10.1038/s41551-026-01721-8. PMID: 38374224.
Unda SR, Pomeranz LE, Marongiu R, Yu X, Kelly L, Hassanzadeh G, Molina H, Vaisey G, Wang P, Dyke JP, Fung EK, Grosenick L, Zirkel R, Antoniazzi AM, Norman S, Liston CM, Schaffer C, Nishimura N, Stanley SA, Friedman JM, Kaplitt MG. Bidirectional Regulation of Motor Circuits Using Magnetogenetic Gene Therapy Short: Magnetogenetic Regulation of Motor Circuits. bioRxiv [Preprint]. 2024 Apr 29:2023.07.13.548699. doi: 10.1101/2023.07.13.548699. Update in: Sci Adv. 2024 Oct 11;10(41):eadp9150. doi: 10.1126/sciadv.adp9150. PMID: 37503198; PMCID: PMC10369996.
An L, Kim D, Donahue LR, Mejooli MA, Eom CY, Nishimura N, White AC. Sexual dimorphism in melanocyte stem cell behavior reveals combinational therapeutic strategies for cutaneous repigmentation. Nat Commun. 2024 Jan 27;15(1):796. doi: 10.1038/s41467-024-45034-3. PMID: 38280858; PMCID: PMC10821900.

O'Brien

2026

Xie Y, Kalia S, Ou KJ, Sun T, Bender E, Lin K, Bottje W, Lei XG, O’Brien KO. 25-Hydroxyvitamin D3 bioenriched chicken and eggs maintained vitamin D status over the winter in healthy-adult males and females: a randomized controlled trial. Am J Clin Nutr. 2026 Nov;124(5):101519. doi: 10.1016/j.ajcnut.2026.101519. Epub 2026 Sep 9. PMID: 42716471.
Lee MR, Barad A, Bender E, Thompson J, Gu Z, Pressman EK, O’Brien KO. Differential associations between menstrual blood loss scores and iron status in East Asian and Northern European individuals: findings from a cross-sectional analysis of the Iron Genes in East Asian and Northern European Adults Study (FeGenes) cohort. Am J Clin Nutr. 2026 Jun;123(6):101326. doi: 10.1016/j.ajcnut.2026.101326. Epub 2026 Apr 25. PMID: 42044770; PMCID: PMC13265119.
Barad A, Xu H, Clark AG, Gu Z, Pressman EK, Ye K, O’Brien KO. A genetic association study of iron absorption in adults of East Asian or Northern European ancestry from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr. 2026 Jun;123(6):101298. doi: 10.1016/j.ajcnut.2026.101298. Epub 2026 Mar 25. PMID: 41895699; PMCID: PMC13173465.
Li Z, Fischbein N, Jin F, Mui W, Co R, Ginsburg AS, Laleau V, Nyquist S, O’Brien KO, Ahituv N, Flaherman V, Golan Y. Methods for Preserving Human Milk Cellular and Milk Fat Globule RNA. J Mammary Gland Biol Neoplasia. 2026 Feb 24;31(1):10. doi: 10.1007/s10911-026-09601-2. PMID: 41733761; PMCID: PMC13035578.

2025

Park CY, Barad A, Xu Y, Bender E, Thomas AK, Haller CM, Gu Z, Pressman EK, O’Brien KO. Dietary intake in East Asian and Northern European participants from the FeGenes study. Eur J Nutr. 2025 Jun 5;64(5):205. doi: 10.1007/s00394-025-03730-w. PMID: 40471375; PMCID: PMC12345378.
Weber DR, O’Brien KO, Ballester L, Rackovsky N, Graulich B, Schwartz GJ. Greater Urinary Calcium Excretion Is Associated With Diminished Bone Accrual in Youth With Type 1 Diabetes. J Clin Endocrinol Metab. 2025 May 19;110(6):e1802-e1810. doi: 10.1210/clinem/dgae660. PMID: 39302657; PMCID: PMC12086414.
Barad A, Xu Y, Bender E, Pressman EK, Gu Z, O’Brien KO. Differences in nonheme iron absorption between healthy adults of East Asian or Northern European ancestry from the Iron Genes in East Asian and Northern European Adults Study (FeGenes): A cross-sectional stable iron isotope study. Am J Clin Nutr. 2025 Feb;121(2):417-426. doi: 10.1016/j.ajcnut.2024.11.015. PMID: 39909711; PMCID: PMC11863334.
Barad A, Xu Y, Bender E, Pressman EK, Gu Z, O’Brien KO. Iron regulatory hormones and their associations with iron status biomarkers among healthy adults of East Asian or Northern European ancestry: A cross-sectional comparison from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr. 2025 Feb;121(2):406-416. doi: 10.1016/j.ajcnut.2024.10.018. PMID: 39909710; PMCID: PMC11863331.
Barad A, Xu Y, Bender E, Kang W, Xu R, Gu Z, Pressman EK, O’Brien KO. Characterization of iron status biomarkers and hematological indices among young adults of East Asian or Northern European ancestry: A cross-sectional analysis from the Iron Genes in East Asian and Northern European Adults Study (FeGenes). Am J Clin Nutr. 2025 Feb;121(2):394-405. doi: 10.1016/j.ajcnut.2024.10.014. PMID: 39909709; PMCID: PMC11863323.

2024

Weber DR, O’Brien KO, Ballester L, Rackovsky N, Graulich B, Schwartz GJ. Greater urinary calcium excretion is associated with diminished bone accrual in youth with type 1 diabetes. J Clin Endocrinol Metab. 2024 Sep 20:dgae660. doi: 10.1210/clinem/dgae660. Epub ahead of print. PMID: 39302657.
Barad A, Clark AG, Pressman EK, O’Brien KO. Associations Between Genetically Predicted Iron Status and Cardiovascular Disease Risk: A Mendelian Randomization Study. J Am Heart Assoc. 2024 Jun 4;13(11):e034991. doi: 10.1161/JAHA.124.034991. Epub 2024 May 31. PMID: 38818967; PMCID: PMC11255641.
Gaffney-Stomberg E, Nakayama AT, Lutz LJ, McClung JP, O’Brien KO, Staab JS. Load carriage exercise increases calcium absorption and retention in healthy young women. J Bone Miner Res. 2024 Mar 4;39(1):39-49. doi: 10.1093/jbmr/zjad003. PMID: 38630876.
Archundia-Herrera MC, Nunes F, Barrios ID, Park CY, Bell RC, O’Brien KO. Development of a Database for the Estimation of Heme Iron and Nonheme Iron Content of Animal-Based Foods. Curr Dev Nutr. 2024 Mar 3;8(4):102130. doi: 10.1016/j.cdnut.2024.102130. PMID: 38545421; PMCID: PMC10963891.
O’Brien KO, Pressman EK. Reply to M Jefferds et al. Am J Clin Nutr. 2024 Jan;119(1):234-235. doi: 10.1016/j.ajcnut.2023.09.028. Epub 2023 Nov 27. PMID: 38176778; PMCID: PMC11347789.
Barad A, Guillet R, Pressman EK, Katzman PJ, Ganz T, Nemeth E, O’Brien KO. Placental ferroportin protein abundance is associated with neonatal erythropoietic activity and iron status in newborns at high risk for iron deficiency and anemia. Am J Clin Nutr. 2024 Jan;119(1):76-86. doi: 10.1016/j.ajcnut.2023.10.022. Epub 2023 Oct 27. PMID: 37890671; PMCID: PMC10808842.

Ophir

2026

Lake J, While GM, Ophir AG, Rubenstein DR, Witczak Oldfather L, Whiting MJ. Vasotocin influences mother-offspring associations in a facultatively family-living lizard. Behav Ecol. 2026 Jul 21;37(5):arag082. doi: 10.1093/beheco/arag082. PMID: 42568864; PMCID: PMC13448473.
Zheng S, Prounis GS, Ophir AG. Interactive impacts of social deprivation and intranasal oxytocin administration on oxytocin receptor density in prairie vole brains. Front Behav Neurosci. 2026 Jun 10;20:1772423. doi: 10.3389/fnbeh.2026.1772423. PMID: 42358615; PMCID: PMC13290860.
Elson MR, Hsu RK, Ophir AG, Prior NH. Beyond Song-An Investigation of Song and Social Preferences in a Monogamous Songbird. Ann N Y Acad Sci. 2026 Mar;1557(1):e70216. doi: 10.1111/nyas.70216. PMID: 41817469.
Sailer LL, Hanadari-Levy A, Ophir AG. Adolescent social instability stress alters social processes in male prairie voles. Front Behav Neurosci. 2026 Feb 24;20:1761549. doi: 10.3389/fnbeh.2026.1761549. PMID: 41816221; PMCID: PMC12971939.

2025

Basurto E, Ophir AG, Montoya B, Cano-Ramírez H, González-Flores O, Suárez-Rodríguez M, Hoffman K. Episodic memory and reproductive condition could independently influence the pair bond maintenance in the male prairie vole (Microtus ochrogaster): Ecological implications and translational relevance in the study of sub-clinical manifestations of schizophrenia. Behav Brain Res. 2025 Aug 24;492:115648. doi: 10.1016/j.bbr.2025.115648. Epub 2025 May 21. PMID: 40409376.

2024

Madrid JE, Pranic NM, Chu S, Bergstrom JJD, Singh R, Rabinovich J, Lopez KA, Ophir AG, Tschida KA. Effects of short-term isolation on social behaviors in prairie voles. PLoS One. 2024 Nov 11;19(11):e0313172. doi: 10.1371/journal.pone.0313172. PMID: 39527561; PMCID: PMC11554233.
Hiura LC, Lazaro VA, Ophir AG. Paternal absence and increased caregiving independently and interactively shape the development of male prairie voles at subadult and adult life stages. Horm Behav. 2024 Aug;164:105605. doi: 10.1016/j.yhbeh.2024.105605. Epub 2024 Jul 19. PMID: 39032207; PMCID: PMC11330720.
Sailer LL, Haghani A, Zoller JA, Li CZ, Ophir AG, Horvath S. Epigenetic aging studies of pair bonding in prairie voles. Sci Rep. 2024 Jul 29;14(1):17439. doi: 10.1038/s41598-024-67641-2. PMID: 39075111; PMCID: PMC11286801.
Forero SA, Liu S, Shetty N, Ophir AG. Re-wiring of the bonded brain: Gene expression among pair bonded female prairie voles changes as they transition to motherhood. Genes Brain Behav. 2024 Jun;23(3):e12906. doi: 10.1111/gbb.12906. PMID: 38861664; PMCID: PMC11166254.
Freeman AR, Arenas S, Lee DN, Singh B, Ophir AG. Characterization of oxytocin and vasopressin receptors in the Southern giant pouched rat and comparison to other rodents. Front Endocrinol (Lausanne). 2024 May 13;15:1390203. doi: 10.3389/fendo.2024.1390203. PMID: 38803478; PMCID: PMC11128605.
Sailer LL, Finton CJ, Patel PP, Bogdanowicz SM, Ophir AG. Dorsal CA1 lesions of the hippocampus impact mating tactics in prairie voles by shifting non-monogamous males’ use of space to resemble monogamous males. Front Behav Neurosci. 2024 Feb 26;18:1355807. doi: 10.3389/fnbeh.2024.1355807. PMID: 38468707; PMCID: PMC10925758.

Osborne

2026

Shuffrey LC, Banker SM, Shapiro-Thompson R, Aschner JL, Bennett S, Bush NR, Blackwell CK, Ghassabian A, Giamberardino SN, Morales S, Newman RB, Osborne LM, Sinsel SE, Sullivan ADW, Tung I, Hockett CW, Elliott AJ; ECHO Cohort Consortium. Association of maternal adverse childhood experiences with inflammatory and growth factor pathway activity during pregnancy: a cross-sectional proteomics-based KEGG pathway analysis in the ECHO cohort. Brain Behav Immun. 2026 Oct 29;140:107090. doi: 10.1016/j.bbi.2026.107090. Epub ahead of print. PMID: 42957063.
Wisner KL, Oberlander TF, Osborne LM, Huybrechts KF. Depression and SSRI Treatment During Pregnancy-Prioritizing Maternal Mental Health. JAMA Psychiatry. 2026 Oct 1;83(10):1062-1069. doi: 10.1001/jamapsychiatry.2026.2405. PMID: 42584886.
Standeven LR, Hudepohl N, Smith C, Etyemez S, Rojas LR, Bajaj M, Osborne LM, Leistikow N, Nagle-Yang S. Using the National Curriculum in Reproductive Psychiatry to Enhance and Standardize Fellowship Training. Acad Psychiatry. 2026 Oct;50(5):594-599. doi: 10.1007/s40596-026-02376-y. Epub 2026 Jul 2. PMID: 42393490.
Osborne LM, Payne JL, Sabunciyan S. Overlapping blood extracellular vesicle mRNA profiles in anxious and euthymic pregnant women who develop postpartum depression. Brain Behav Immun. 2026 Oct;137:106867. doi: 10.1016/j.bbi.2026.106867. Epub 2026 Jun 10. PMID: 42269886; PMCID: PMC13374013.
Khanna D, Toscano M, Park S, Rahman A, Atif N, Osborne LM, Malik A, Surkan PJ. Maternal Responsiveness, Parenting Self-efficacy, and Economic Empowerment: Determinants of Infant Development in Pakistan. J Dev Behav Pediatr. 2026 Sep-Oct 01;47(5):e546-e553. doi: 10.1097/DBP.0000000000001481. Epub 2026 Apr 15. PMID: 41984574; PMCID: PMC13266541.
Beal ML, Osborne LM, Nagle-Yang S. Reproductive Psychiatry Tracks: An Examination of Subspecialty Training During Consultation-Liaison Fellowship. Acad Psychiatry. 2026 Aug;50(4):512-513. doi: 10.1007/s40596-026-02315-x. Epub 2026 Mar 3. PMID: 41776137.
Cox RC, Hoyniak CP, Samuels J, Abramowitz JS, Nestadt G, Storch EA, Musci R, Nestadt P, Osborne LM, Kimmel M. Subjective sleep disruption, coping, and anxiety and related symptoms in the perinatal period: findings from a longitudinal study. Sleep. 2026 Jul 13;49(7):zsag089. doi: 10.1093/sleep/zsag089. PMID: 41920960; PMCID: PMC13148649.
Koire A, Cirino N, Sager M, Mergler R, Teslyar P, Osborne LM, Byatt N, Liu CH. Advancing Women’s Mental Health Education in Psychiatry Residency Training Programs: Insights from a Trainee Needs Assessment. Psychiatr Q. 2026 Jun;97(2):273-288. doi: 10.1007/s11126-026-10267-6. Epub 2026 Mar 13. PMID: 41824230.
Staniczenko AP, Dean JR, Voegtline K, Thomas C, Abedian S, Sholle E, Yen S, Cron J, Osborne LM, Lipkind HS, Son M. Social Vulnerability Index and Its Association With Postpartum Care Attendance. Obstet Gynecol. 2026 May 1;147(5):e97-e105. doi: 10.1097/AOG.0000000000006129. Epub 2025 Nov 20. PMID: 41264920; PMCID: PMC13067376.
Bergink V, Akbarian S, Byatt N, Chandra PS, Cirino N, Dazzan P, De Witte L, Di Florio A, Dolman C, Jones I, Kamperman A, Mahjani B, Meltzer-Brody S, Munk-Olsen T, Nagle-Yang S, Osborne LM, Rasgon N, Robakis T, Thippeswamy H, Vigod SN, Payne JL. Postpartum Psychosis and Bipolar Disorder: Review of Neurobiology and Expert Consensus Statement on Classification. Biol Psychiatry. 2026 May 1;99(9):740-747. doi: 10.1016/j.biopsych.2025.10.016. Epub 2025 Oct 22. PMID: 41135771; PMCID: PMC12673989.
Miller ES, Cunningham SK, Osborne LM. Perinatal Depression-Reply. JAMA. 2026 Apr 14;335(14):1270. doi: 10.1001/jama.2026.0103. PMID: 41779419.
Malik A, Liaqat R, Suleman N, Etyemez S, Ahmed B, Asif R, Khan SA, Surkan PJ, Osborne LM. Biopsychosocial stressors and perinatal mental health: The mediating role of social support in a Pakistani cohort. Glob Ment Health (Camb). 2026 Apr 1;13:e82. doi: 10.1017/gmh.2026.10184. PMID: 42051787; PMCID: PMC13112274.
Lebin LG, Frew JR, Osborne LM, Standeven LR, Nagle-Yang S. Needs Assessment to Inform Future Development of the National Curriculum in Reproductive Psychiatry. Acad Psychiatry. 2026 Apr;50(2):231-236. doi: 10.1007/s40596-025-02283-8. Epub 2025 Nov 25. PMID: 41291303.
Njoh J, Abramowitz JS, Musci R, Kimmel MC, Osborne LM, Samuels J, Nestadt P, Nestadt G, Storch EA. Perinatal obsessive-compulsive symptoms and maternal-infant bonding: A longitudinal examination of depression and relationship quality. Arch Womens Ment Health. 2026 Mar 28;29(2):56. doi: 10.1007/s00737-026-01694-2. PMID: 41896388; PMCID: PMC13031229.
Islam MS, Park S, Malik A, Atif N, Osborne LM, Perin J, Rahman A, Surkan PJ. Psychometric properties of the Urdu version of the Postpartum Bonding Questionnaire (PBQ): a validation study among mothers with prenatal anxiety symptoms in Pakistan. Arch Womens Ment Health. 2026 Jan 20;29(1):22. doi: 10.1007/s00737-025-01661-3. PMID: 41555059; PMCID: PMC13290297.
Samuels J, Kimmel M, Krasnow J, Musci R, Nestadt PS, Osborne LM, Storch EA, Abramowitz JS, Nestadt G. Onset and exacerbation of obsessive-compulsive disorder in the perinatal period. Arch Womens Ment Health. 2026 Jan 16;29(1):19. doi: 10.1007/s00737-025-01647-1. PMID: 41540218; PMCID: PMC12808193.
Etyemez S, Mehta K, Faiz J, Ahmad M, Zaidi A, Atif N, Rahman A, Malik A, Voegtline KM, Surkan PJ, Osborne LM. Vitamin D levels and perinatal anxiety in an anxiety-focused behavioral intervention program in Pakistan. Arch Womens Ment Health. 2026 Jan 7;29(1):11. doi: 10.1007/s00737-025-01653-3. PMID: 41498950.

2025

Miller ES, Cunningham SK, Osborne LM. Pharmacologic Treatment of Perinatal Depression. JAMA. 2025 Dec 23;334(24):2223-2224. doi: 10.1001/jama.2025.17250. PMID: 41259042.
Faiz JM, Bylinsky I, Rincones Rojas L, Kopatsis K, St Clair V, Dorval-Moller M, Voegtline K, Lipkind H, Safford MM, Hall KS, Reddy U, Osborne LM. Doula-Delivered Cognitive Behavioral Training and Cardiovascular Health Intervention for Birthing Individuals in a Low-Income New York City Population: Protocol for a Living Healthy for Moms Randomized Type I Hybrid Effectiveness-Implementation Trial. JMIR Res Protoc. 2025 Dec 10;14:e76871. doi: 10.2196/76871. PMID: 41370009; PMCID: PMC12739457.
Society for Maternal‐Fetal Medicine (SMFM); Carter EB, Cohen L, Kim P, Miller ES, Monk C, Osborne LM, Sciscione A. Report: Workshop on maternal mental health, February 11-12, 2024, cosponsored by the American College of Obstetricians and Gynecologists. Pregnancy (Hoboken). 2025 Oct 28;1(6):e70121. doi: 10.1002/pmf2.70121. PMID: 42597098; PMCID: PMC13344629.
Bergink V, Akbarian S, Byatt N, Chandra PS, Cirino N, Dazzan P, De Witte L, Di Florio A, Dolman C, Jones I, Kamperman A, Mahjani B, Meltzer-Brody S, Munk-Olsen T, Nagle-Yang S, Osborne LM, Rasgon N, Robakis T, Thippeswamy H, Vigod SN, Payne JL. Postpartum Psychosis and Bipolar Disorder: Review of Neurobiology and Expert Consensus Statement on classification. Biol Psychiatry. 2025 Oct 22:S0006-3223(25)01536-7. doi: 10.1016/j.biopsych.2025.10.016. Epub ahead of print. PMID: 41135771.
Osborne LM, Appelbaum P, Watson K, Yonkers K, Burnett-Zeigler I, Epperson CN, Monk C, Wisner KL. US Abortion Restrictions and the Neuropsychiatric Health of Pregnant Individuals and Families. JAMA Psychiatry. 2025 Oct 1;82(10):1025-1029. doi: 10.1001/jamapsychiatry.2025.1376. PMID: 40668571.
Solomonov N, Kerchner D, Dai Y, Kwon M, Callaghan DG, Schier MM, Zhang Y, Osborne LM, Benda NC. Prevalence and Trajectories of Perinatal Anxiety and Depression in a Large Urban Medical Center. JAMA Netw Open. 2025 Sep 2;8(9):e2533111. doi: 10.1001/jamanetworkopen.2025.33111. PMID: 40982279; PMCID: PMC12455385.
Temkin-Yu AB, Oh A, Siegel IE, Liu MX, Seewald MJ, Blicker E, Ayaz A, Hermann AD, Givrad S, Baez LM, Osborne LM, Green CM, Schier MM, Falk A, Bennett SM. A novel app-based cognitive behavioral perinatal skills program: A case series. Digit Health. 2025 Sep 29;11:20552076251382084. doi: 10.1177/20552076251382084. PMID: 41036437; PMCID: PMC12480806.
Abramowitz JS, Hellberg SN, Krasnow J, Friedman JB, Myers NS, Nestadt PS, Ojalehto HJ, Juel EK, Samuels J, Kimmel ME, Osborne LM, Storch EA, Nestadt G, Musci RJ. Prenatal obsessive beliefs predict postpartum obsessive-compulsive symptoms: a prospective study. Psychiatry Res. 2025 Sep;351:116620. doi: 10.1016/j.psychres.2025.116620. Epub 2025 Jun 30. PMID: 40628003; PMCID: PMC12321878.
Rast CE, Musci R, Abramowitz JS, Nestadt G, Nestadt P, Kimmel MC, Dibbs T, Osborne LM, Samuels J, Krasnow J, Storch EA. Psychometric evaluation of the Yale-Brown Obsessive-Compulsive Scale in pregnant women. Arch Womens Ment Health. 2025 Aug;28(4):919-926. doi: 10.1007/s00737-024-01548-9. Epub 2025 Jan 2. Erratum in: Arch Womens Ment Health. 2025 Aug;28(4):965. doi: 10.1007/s00737-025-01580-3. PMID: 39745521; PMCID: PMC12321150.
Abramowitz JS, Myers NS, Friedman JB, Juel EK, Nestadt G, Kimmel M, Osborne LM, Storch EA, Samuels J, Nestadt PS, Musci R. Psychometric properties of the OCI-4: a brief screening tool for perinatal obsessive-compulsive disorder. Arch Womens Ment Health. 2025 Aug;28(4):895-902. doi: 10.1007/s00737-024-01539-w. Epub 2024 Nov 30. PMID: 39613898; PMCID: PMC12303159.
Etyemez S, Mehta K, Iyer S, Özdemir İ, Osborne LM. Biomarkers of reproductive psychiatric disorders. Br J Psychiatry. 2025 Jun;226(6):352-368. doi: 10.1192/bjp.2025.134. Epub 2025 Jun 20. PMID: 40538358; PMCID: PMC12257282.
Osborne LM, Etyemez S, Pinna G, Alemani R, Standeven LR, Wang XQ, Payne JL. Correction: Neuroactive steroid biosynthesis during pregnancy predicts future postpartum depression: a role for the 3α and/or 3β-HSD neurosteroidogenic enzymes? Neuropsychopharmacology. 2025 May;50(6):1021. doi: 10.1038/s41386-025-02109-z. Erratum for: Neuropsychopharmacology. 2025 May;50(6):904-912. doi: 10.1038/s41386-025-02052-z. PMID: 40247014; PMCID: PMC12032098.
Okun ML, Payne JL, Osborne LM, Feliciano L, Lac A. Effects of Using a Smart Bassinet on the Mental Health of Military-Affiliated Pregnant Women: Protocol for a Randomized Controlled Sleep Health and Mood in Newly Expectant Military Mothers (SHINE) Trial. JMIR Res Protoc. 2025 Apr 10;14:e66439. doi: 10.2196/66439. PMID: 40209215; PMCID: PMC12022534.
Rast CE, Dibbs T, Pinciotti CM, Jagannathan N, Abramowitz JS, Kimmel MC, Musci R, Nestadt G, Nestadt P, Osborne LM, Samuels J, Storch EA. Psychometric properties of the postpartum thoughts and behaviors checklist. J Obsessive Compuls Relat Disord. 2025 Apr;45:100939. doi: 10.1016/j.jocrd.2025.100939. Epub 2025 Feb 19. PMID: 40831602; PMCID: PMC12360429.
Schoretsanitis G, Osborne LM, Sundström-Poromaa I, Wenzel ES, Payne JL, Barbui C, Gastaldon C, Deligiannidis KM. Peripartum allopregnanolone blood concentrations and depressive symptoms: a systematic review and individual participant data meta-analysis. Mol Psychiatry. 2025 Mar;30(3):1148-1160. doi: 10.1038/s41380-024-02747-7. Epub 2024 Nov 7. PMID: 39511449; PMCID: PMC11835716.
Hantsoo L, Osborne LM, Susser LC. Editorial: Psychiatric illness across the menstrual cycle. Front Psychiatry. 2025 Feb 12;16:1568088. doi: 10.3389/fpsyt.2025.1568088. PMID: 40012716; PMCID: PMC11862688.
Drexhage HA, Bergink V, Poletti S, Benedetti F, Osborne LM. Conventional and new immunotherapies for immune system dysregulation in postpartum mood disorders: comparisons to immune system dysregulations in bipolar disorder, major depression, and postpartum autoimmune thyroid disease. Expert Rev Clin Immunol. 2025 Feb;21(2):113-135. doi: 10.1080/1744666X.2024.2420053. Epub 2024 Oct 29. PMID: 39441185; PMCID: PMC11786996.
Surkan PJ, Park S, Sheng Z, Zaidi A, Atif N, Osborne LM, Rahman A, Malik A. Effects of a Prenatal Anxiety Randomized Controlled Trial Intervention on Infant Development in Pakistan. Acad Pediatr. 2025 Jan-Feb;25(1):102551. doi: 10.1016/j.acap.2024.07.018. Epub 2024 Aug 2. PMID: 39097000; PMCID: PMC11833752.
Temkin-Yu AB, Ayaz A, Blicker E, Liu MX, Oh A, Siegel IE, Seewald MJ, Hermann AD, Givrad S, Baez LM, Osborne LM, Green CM, Schier MM, Davis AM, Zhu S, Falk A, Bennett SM. Feasibility of a Mobile App-Based Cognitive-Behavioral Perinatal Skills Program: Protocol for Nonrandomized Pilot Trial. JMIR Res Protoc. 2025 Jan 28;14:e59461. doi: 10.2196/59461. PMID: 39874578; PMCID: PMC11815301.
Hart A, Weiss-Goldman N, Halpern J, Bennett F, White LA, Birndorf C, Van Nortwick N, Osborne LM, Robakis TK. Attachment classification and early adversity predict perinatal partial hospital treatment response. J Affect Disord. 2025 Jan 15;369:182-187. doi: 10.1016/j.jad.2024.09.139. Epub 2024 Sep 24. PMID: 39326587.

2024

Schoretsanitis G, Osborne LM, Sundström-Poromaa I, Wenzel ES, Payne JL, Barbui C, Gastaldon C, Deligiannidis KM. Peripartum allopregnanolone blood concentrations and depressive symptoms: a systematic review and individual participant data meta-analysis. Mol Psychiatry. 2024 Nov 7. doi: 10.1038/s41380-024-02747-7. Epub ahead of print. PMID: 39511449.
Barone JC, Ho A, Osborne LM, Eisenlohr-Moul TA, Morrow AL, Payne JL, Epperson CN, Hantsoo L. Luteal phase sertraline treatment of premenstrual dysphoric disorder (PMDD): Effects on markers of hypothalamic pituitary adrenal (HPA) axis activation and inflammation. Psychoneuroendocrinology. 2024 Nov;169:107145. doi: 10.1016/j.psyneuen.2024.107145. Epub 2024 Jul 24. PMID: 39096755; PMCID: PMC11381144.
Drexhage HA, Bergink V, Poletti S, Benedetti F, Osborne LM. Conventional and new immunotherapies for immune system dysregulation in postpartum mood disorders: comparisons to immune system dysregulations in bipolar disorder, major depression, and postpartum autoimmune thyroid disease. Expert Rev Clin Immunol. 2024 Oct 29:1-23. doi: 10.1080/1744666X.2024.2420053. Epub ahead of print. PMID: 39441185.
Standeven LR, Bajaj M, McEvoy K, Shirinian D, Voegtline K, Osborne LM, Payne JL, Hantsoo L. The link between childhood traumatic events and the continuum of premenstrual disorders. Front Psychiatry. 2024 Oct 9;15:1443352. doi: 10.3389/fpsyt.2024.1443352. PMID: 39444627; PMCID: PMC11496889.
Osborne LM, Monk C. Perinatal mental health: Research that moves the agenda forward. Semin Perinatol. 2024 Oct;48(6):151952. doi: 10.1016/j.semperi.2024.151952. Epub 2024 Jul 14. PMID: 39034178.
Hart A, Weiss-Goldman N, Halpern J, Bennett F, White LA, Birndorf C, Van Nortwick N, Osborne LM, Robakis TK. Attachment classification and early adversity predict perinatal partial hospital treatment response. J Affect Disord. 2024 Sep 24;369:182-187. doi: 10.1016/j.jad.2024.09.139. Epub ahead of print. PMID: 39326587.
Etyemez S, Mehta K, Tutino E, Zaidi A, Atif N, Rahman A, Malik A, Voegtline KM, Surkan PJ, Osborne LM. The immune phenotype of perinatal anxiety in an anxiety-focused behavioral intervention program in Pakistan. Brain Behav Immun. 2024 Aug;120:141-150. doi: 10.1016/j.bbi.2024.05.028. Epub 2024 May 21. PMID: 38777289.
Sha Q, Escobar Galvis ML, Madaj ZB, Keaton SA, Smart L, Edgerly YM, Anis E, Leach R, Osborne LM, Achtyes E, Brundin L. Dysregulated placental expression of kynurenine pathway enzymes is associated with inflammation and depression in pregnancy. Brain Behav Immun. 2024 Jul;119:146-153. doi: 10.1016/j.bbi.2024.03.042. Epub 2024 Mar 29. PMID: 38555986; PMCID: PMC11210184.
Son M, Riley LE, Staniczenko AP, Cron J, Yen S, Thomas C, Sholle E, Osborne LM, Lipkind HS. Nonadjuvanted Bivalent Respiratory Syncytial Virus Vaccination and Perinatal Outcomes. JAMA Netw Open. 2024 Jul 1;7(7):e2419268. doi: 10.1001/jamanetworkopen.2024.19268. PMID: 38976271; PMCID: PMC11231799.
DeMairo J, Rimsky L, Moses A, Birndorf C, Bellenbaum P, Van Nortwick N, Osborne LM, Robakis TK. Outcomes at the Motherhood Center: A Comparison of Virtual and On-Site Versions of a Specialized Perinatal Partial Hospitalization Program. Matern Child Health J. 2024 May;28(5):828-835. doi: 10.1007/s10995-023-03836-9. Epub 2023 Nov 15. PMID: 37964152.
Smirnova L, Modafferi S, Schlett C, Osborne LM, Payne JL, Sabunciyan S. Blood extracellular vesicles carrying brain-specific mRNAs are potential biomarkers for detecting gene expression changes in the female brain. Mol Psychiatry. 2024 Apr;29(4):962-973. doi: 10.1038/s41380-023-02384-6. Epub 2024 Jan 11. PMID: 38212371.
Weingarten SJ, Osborne LM. Review of the Assessment and Management of Perinatal Mood and Anxiety Disorders. Focus (Am Psychiatr Publ). 2024 Jan;22(1):16-24. doi: 10.1176/appi.focus.20230023. Epub 2024 Jan 12. PMID: 38694149; PMCID: PMC11058917.

Owens

2026

Owens CE, Borruso AJ, Place KA, Seluanov A, Gorbunova V, White PM, Place NJ. Age-related hearing loss persisted in mice that had demonstrated improved healthspan, reduced inflammaging and extended lifespan following expression of the naked mole-rat transgene for hyaluronan synthase 2. Front Aging. 2026 Aug 27;7:1936677. doi: 10.3389/fragi.2026.1936677. PMID: 42724209; PMCID: PMC13558403.
Tanis S, Simon LE, Alexander AK, Horan TS, Carro MLM, Bonnett SJ, Xie A, Ben-Shlomo R, Owens CE, Danko CG, Lujic J, Cohen PE. Meiotic prophase I disruption as a strategy for nonhormonal male contraception using small-molecule inhibitor JQ1. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2517498123. doi: 10.1073/pnas.2517498123. Epub 2026 Apr 7. PMID: 41945432; PMCID: PMC13080027.

Palermo

2025

Kuchakulla M, Gurayah AA, Marinaro JA, Brant A, Gaffney CD, Xie P, Punjani N, Kang C, Gal J, Palermo GD, Kashanian JA. Impact of microsurgical varicocelectomy on sperm capacitation and birth outcomes. BJU Int. 2025 Dec;136(6):1064-1070. doi: 10.1111/bju.16888. Epub 2025 Aug 12. PMID: 40797084.
Xie P, Takeuchi T, Cheung S, Rosenwaks Z, Palermo GD. Male gamete copies to characterize genome inheritance and generate progenies. Sci Rep. 2025 May 4;15(1):15600. doi: 10.1038/s41598-025-99188-1. PMID: 40320458; PMCID: PMC12050308.
Kocur OM, Xie P, Cheung S, Ng L, De Jesus A, Rosenwaks Z, Palermo GD. The intricate “ART” of ICSI. J Assist Reprod Genet. 2025 Feb;42(2):349-365. doi: 10.1007/s10815-024-03322-3. Epub 2024 Dec 23. PMID: 39714737; PMCID: PMC11871271.

2024

Ng L, Kocur OM, Xie P, Cheung S, Schlegel P, Rosenwaks Z, Palermo GD. Reply by Authors. J Urol. 2024 May;211(5):689. doi: 10.1097/JU.0000000000003923. Epub 2024 Mar 20. PMID: 38506301.
Ng L, Kocur OM, Xie P, Cheung S, Schlegel P, Rosenwaks Z, Palermo GD. Timing of Testicular Biopsy in Relation to Oocyte Retrieval and the Outcomes of Intracytoplasmic Sperm Injection. J Urol. 2024 May;211(5):678-686. doi: 10.1097/JU.0000000000003894. Epub 2024 Feb 20. PMID: 38375822; PMCID: PMC12721619.
Xie P, Cheung S, Kocur O, Ng L, De Jesus A, Rosenwaks Z, Palermo GD, Aitken RJ, Schlegel PN. Intracytoplasmic sperm injection is still the best management of male factor infertility. Fertil Steril. 2024 Apr;121(4):563-575. doi: 10.1016/j.fertnstert.2024.02.025. PMID: 38538181.
Cheung S, Ng L, Xie P, Kocur O, Elias R, Schlegel P, Rosenwaks Z, Palermo GD. Genetic profiling of azoospermic men to identify the etiology and predict reproductive potential. J Assist Reprod Genet. 2024 Apr;41(4):1111-1124. doi: 10.1007/s10815-024-03045-5. Epub 2024 Feb 26. PMID: 38403804; PMCID: PMC11052749.

2023

Marinaro JA, Brant A, Kang C, Punjani N, Xie P, Zaninovic N, Palermo GD, Rosenwaks Z, Schlegel PN. Successful cryptozoospermia management with multiple semen specimen collection. Fertil Steril. 2023 Nov;120(5):996-1003. doi: 10.1016/j.fertnstert.2023.07.019. Epub 2023 Jul 28. PMID: 37517636.
Kocur OM, Xie P, Cheung S, Souness S, McKnight M, Rosenwaks Z, Palermo GD. Can a sperm selection technique improve embryo ploidy? Andrology. 2023 Nov;11(8):1605-1612. doi: 10.1111/andr.13362. Epub 2022 Dec 28. PMID: 36484212; PMCID: PMC10959494.
Xie P, Kocur OM, Cheung S, Ng L, Albertini DF, Rosenwaks Z, Palermo GD. Sperm centriolar factors and genetic defects that can predict pregnancy. Fertil Steril. 2023 Oct;120(4):720-728. doi: 10.1016/j.fertnstert.2023.07.007. Epub 2023 Jul 22. PMID: 37487819.
Setton R, Xie P, Rosenwaks Z, Palermo GD. A novel approach toward the generation of oocytes by direct diploid cell haploidization. Zygote. 2023 Jun;31(3):266-272. doi: 10.1017/S0967199423000096. Epub 2023 Mar 30. PMID: 36992663.
Cheung S, Elias R, Xie P, Rosenwaks Z, Palermo GD. A non-randomized clinical trial to determine the safety and efficacy of a novel sperm sex selection technique. PLoS One. 2023 Mar 22;18(3):e0282216. doi: 10.1371/journal.pone.0282216. PMID: 36947521; PMCID: PMC10032484.
Cheung S, Xie P, Rosenwaks Z, Palermo GD. Profiling the male germline genome to unravel its reproductive potential. Fertil Steril. 2023 Feb;119(2):196-206. doi: 10.1016/j.fertnstert.2022.11.006. Epub 2022 Nov 12. PMID: 36379263; PMCID: PMC9898105.
Kocur OM, Xie P, Souness S, Cheung S, Rosenwaks Z, Palermo GD. Assessing male gamete genome integrity to ameliorate poor assisted reproductive technology clinical outcome. F S Sci. 2023 Feb;4(1):2-10. doi: 10.1016/j.xfss.2022.08.001. Epub 2022 Aug 13. PMID: 35973556; PMCID: PMC10959493.
Shapouri F, Mahendran T, Govindarajan M, Xie P, Kocur O, Palermo GD, Bakos HW, Ahlström A, Caisander G, Xu B, Bai S, Lambourne S, Aitken RJ. A comparison between the Felix™ electrophoretic system of sperm isolation and conventional density gradient centrifugation: a multicentre analysis. J Assist Reprod Genet. 2023 Jan;40(1):83-95. doi: 10.1007/s10815-022-02680-0. Epub 2022 Dec 14. PMID: 36515800; PMCID: PMC9840737.

2022

Xie P, Aluko A, Cheung S, Goldschlag D, Davis O, Rosenwaks Z, Palermo GD. Assisted gamete treatment to pinpoint acquired meiotic maturity and overcome oocyte activation deficiency contributed by both gametes. F S Rep. 2022 Dec 30;4(1):72-76. doi: 10.1016/j.xfre.2022.12.006. PMID: 36959954; PMCID: PMC10028469.
Brant A, Punjani N, Zaninovic N, Palermo GD, Rosenwaks Z, Schlegel PN. Effects of Chemo- and Radiation Therapy on Microsurgical Testicular Sperm Extraction for Men with Nonobstructive Azoospermia. J Urol. 2022 Sep;208(3):676-683. doi: 10.1097/JU.0000000000002728. Epub 2022 May 2. PMID: 35499482.
Punjani N, Aboukhshaba A, Doukakis S, Zaninovic N, Palermo GD, Schlegel PN. Reply of the Authors: Testicular sperm characteristics in men with nonobstructive azoospermia and their impact on intracytoplasmic sperm injection outcome. Fertil Steril. 2022 Aug;118(2):427. doi: 10.1016/j.fertnstert.2022.05.021. Epub 2022 Jun 16. PMID: 35717286.
Lee Y, Trout A, Marti-Gutierrez N, Kang S, Xie P, Mikhalchenko A, Kim B, Choi J, So S, Han J, Xu J, Koski A, Ma H, Yoon JD, Van Dyken C, Darby H, Liang D, Li Y, Tippner-Hedges R, Xu F, Amato P, Palermo GD, Mitalipov S, Kang E. Haploidy in somatic cells is induced by mature oocytes in mice. Commun Biol. 2022 Jan 25;5(1):95. doi: 10.1038/s42003-022-03040-5. PMID: 35079104; PMCID: PMC8789866.

2021

Xie P, Cheung S, Kocur OM, Rosenwaks Z, Palermo GD. Sperm DNA fragmentation: What have we learned so far? Fertil Steril. 2021 Dec;116(6):1491. doi: 10.1016/j.fertnstert.2021.09.029. Epub 2021 Nov 5. PMID: 34743912.
Cheung S, Parrella A, Tavares D, Keating D, Xie P, Rosenwaks Z, Palermo GD. Single-center thorough evaluation and targeted treatment of globozoospermic men. J Assist Reprod Genet. 2021 Aug;38(8):2073-2086. doi: 10.1007/s10815-021-02191-4. Epub 2021 Apr 20. PMID: 33877510; PMCID: PMC8417186.
Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C. In vitro fertilization and andrology laboratory in 2030: expert visions. Fertil Steril. 2021 Jul;116(1):4-12. doi: 10.1016/j.fertnstert.2021.05.088. PMID: 34148588.
Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L. In vitro fertilization and andrology laboratories in 2030. Fertil Steril. 2021 Jul;116(1):2-3. doi: 10.1016/j.fertnstert.2021.05.089. Erratum in: Fertil Steril. 2021 Sep;116(3):917. doi: 10.1016/j.fertnstert.2021.06.048. PMID: 34148585.
Cheung S, Neri QV, Squires J, Rosenwaks Z, Palermo GD. Assessing the cognitive and behavioral development of 3-year-old children born from fathers with severe male infertility. Am J Obstet Gynecol. 2021 May;224(5):508.e1-508.e11. doi: 10.1016/j.ajog.2020.11.030. Epub 2020 Nov 26. PMID: 33248137.
Haddad M, Stewart J, Xie P, Cheung S, Trout A, Keating D, Parrella A, Lawrence S, Rosenwaks Z, Palermo GD. Thoughts on the popularity of ICSI. J Assist Reprod Genet. 2021 Jan;38(1):101-123. doi: 10.1007/s10815-020-01987-0. Epub 2020 Nov 6. PMID: 33155089; PMCID: PMC7823003.

Permar

2025

Connors MR, Karthigeyan KP, Fuller AS, Mitchell L, Preston H, Ananyev S, Crooks CM, Stanton R, Anderson DE, Permar SR. Specificity and functional humoral immune responses induced by the VBI-1501A eVLP HCMV gB vaccine compared to the gB/MF59 vaccine. Hum Vaccin Immunother. 2025 Dec;21(1):2564555. doi: 10.1080/21645515.2025.2564555. Epub 2025 Sep 24. PMID: 40990374; PMCID: PMC12461891.
McGinty EE, Bitton A, Permar SR. Medicaid Cuts and U.S. Children’s Health – Fixing a Broken System. N Engl J Med. 2025 Nov 6;393(18):1766-1769. doi: 10.1056/NEJMp2509878. Epub 2025 Nov 1. PMID: 41181905.
Obregon-Perko V, Awasthi A, Barfield R, Berendam SJ, Yagnik B, Styles T, Tharp G, Gupta PM, Mensah G, Neja M, Kumar M, Fray E, Bu F, Pollara J, Tuyishime M, Ferrari G, Siliciano JD, Siliciano RF, Mavigner M, Silvestri G, Amara RR, Bosinger S, Fouda GG, Permar SR, Chan C, Chahroudi A. Identifying correlates of viral rebound timing and viral control in SHIV-infected infant macaques after ART interruption. Sci Transl Med. 2025 Oct 29;17(822):eadq1965. doi: 10.1126/scitranslmed.adq1965. Epub 2025 Oct 29. PMID: 41160668.
Anronikov S, Meikle C, Milligan EC, Chen H, Mukherjee N, Bjornson Z, Gaudillière B, Jiang S, Permar SR, Van Rompay KKA, Nolan GP, De Paris K, McIlwain DR. Comparative single-cell immune responses in peripheral blood and lymph node of immunized SARS-CoV-2 challenged infant rhesus macaques. Front Immunol. 2025 Sep 15;16:1599408. doi: 10.3389/fimmu.2025.1599408. PMID: 41030442; PMCID: PMC12477255.
Giorgi EE, Abrahams MR, Fouda G, John-Stewart G, Goga A, Mullins JI, Permar SR, Janes HE, Martin TM. Characterization of Early Viral Populations in Infants Acquiring HIV Through Perinatal and Breastmilk Transmission: A Review of what is Currently Known and the Gaps that Need to be Addressed to Guide Passive HIV Immunization of Breastfeeding Infants. Curr HIV Res. 2025 Sep 4. doi: 10.2174/011570162X357975250902104402. Epub ahead of print. PMID: 40916416.
Hills LB, Bhat N, Hurst JH, Myers A, Burke TW, McClain MT, Petzold E, Rotta AT, Turner NA, Grifoni A, Weiskopf D, Dogariu Y, Fouda GG, Permar SR, Sette A, Woods CW, Kelly MS, Crotty S. Pediatric T cell and B cell responses to SARS-CoV-2 infection. JCI Insight. 2025 Sep 4;10(20):e196032. doi: 10.1172/jci.insight.196032. PMID: 40906527; PMCID: PMC12581660.
Fouda GG, Singh A, Nelson A, Janes H, Martin T, Levy O, Wu D, Zou F, Jean-Philippe P, De Paris K, Van Rompay KKA, Permar SR. Integration of Preclinical and Clinical Vaccine Safety and Immunogenicity Testing for Development of a Pediatric HIV Vaccine to Achieve Protective HIV Immunity Prior to Adolescence. Curr HIV Res. 2025 Aug 8. doi: 10.2174/011570162X366522250721113420. Epub ahead of print. PMID: 40798950.
Permar SR, Wilson PC. Evolving rare B cell lineages for an effective HIV vaccine. Science. 2025 Jul 31;389(6759):455-457. doi: 10.1126/science.adz6436. Epub 2025 Jul 31. PMID: 40743359.
Karthigeyan KP, Connors M, Binuya CR, Gross M, Fuller AS, Crooks CM, Wang H-Y, Sponholtz MR, Byrne PO, Herbek S, Andy C, Gerber LM, Campbell JD, Williams CA, Mitchell E, van der Maas L, Miller I, Yu D, Bottomley MJ, McLellan JS, Permar SR. A human cytomegalovirus prefusion-like glycoprotein B subunit vaccine elicits humoral immunity similar to that of postfusion gB in mice. J Virol. 2025 Jun 17;99(6):e0217824. doi: 10.1128/jvi.02178-24. Epub 2025 May 8. PMID: 40338082; PMCID: PMC12172439.
Williams CA, Murphy EA, Gross M, Herbek S, Mohammed I, Sukhu AC, Salvatore CM, Prabhu M, Johnston CD, Riley LE, Permar SR, Yang YJ. SARS-CoV-2 Vaccine-Elicited Antibody Responses in Human Milk. J Pediatric Infect Dis Soc. 2025 Jun 16;14(6):piae086. doi: 10.1093/jpids/piae086. PMID: 39238169; PMCID: PMC12399877.
Issah YA, Hu X, Isaac J, Shen X, Davis D, Ozorowski G, Sewall LM, Zhang S, Kang E, Vuong K, Dennis M, Chen JL, Ramos JM, Yasmeen A, Eudailey J, Cupo A, Weinbaum C, Gao H, Stanfield-Oakley S, Ferrari G, Klasse PJ, Fouda G, Hudgens M, Ward AB, Montefiori DC, Sanders RW, Moore JP, Van Rompay KKA, De Paris K, Permar SR, Nelson AN. Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques. bioRxiv [Preprint]. 2025 May 30:2025.05.27.656273. doi: 10.1101/2025.05.27.656273. PMID: 40501834; PMCID: PMC12154809.
Jiang D, Soo N, Tan CY, Dankwa S, Wang HY, Theriot BS, Xue K, Hill D, Ardeshir A, Bain JR, Heston SM, Hurst JH, Siddiqui NY, Van Rompay KKA, Cervantes-Barragan L, Smith JP, Song R, Roper J, Kelly MS, Hudgens MG, Paris K, Permar SR, Goswami R, Surana NK. Commensal bacteria inhibit viral infections via a tryptophan metabolite. bioRxiv [Preprint]. 2025 May 12:2024.04.21.589969. doi: 10.1101/2024.04.21.589969. PMID: 38659737; PMCID: PMC11042330.
Bahadir Z, Narayan P, Wolters R, Permar SR, Fouda G, Hessell AJ, Haigwood NL. Monoclonal Antibodies for Pediatric Viral Disease Prevention and Treatment. Pediatrics. 2025 May 1;155(5):e2024068690. doi: 10.1542/peds.2024-068690. PMID: 40174915.
Langel SN, Otero CE, Steppe JT, Williams CA, Travieso T, Chang J, Webster H, Williamson LE, Crowe JE Jr, Greenberg HB, Wu H, Hornik CP, Mansouri K, Edwards RJ, Stalls V, Acharya P, Blasi M, Permar SR. Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus. Mucosal Immunol. 2025 Apr;18(2):441-452. doi: 10.1016/j.mucimm.2025.01.002. Epub 2025 Jan 20. PMID: 39842610; PMCID: PMC11982437.
Alba C, Malhotra S, Horsfall S, Barnhart ME, Bekker A, Chapman K, Cunningham CK, Fast PE, Fouda GG, Freedberg KA, Goga A, Ghazaryan LR, Leroy V, Mann C, McCluskey MM, McFarland EJ, Muturi-Kioi V, Permar SR, Shapiro R, Sok D, Stranix-Chibanda L, Weinstein MC, Ciaranello AL, Dugdale CM. Cost-effectiveness of broadly neutralizing antibodies for HIV prophylaxis for infants born in settings with high HIV burdens. PLoS One. 2025 Mar 19;20(3):e0318940. doi: 10.1371/journal.pone.0318940. PMID: 40106399; PMCID: PMC11922280.
Wang HY, Taher H, Kreklywich CN, Schmidt KA, Scheef EA, Barfield R, Otero CE, Valencia SM, Zhang K, Callahan C, Monticolo F, Qiao Y, Gilbride RM, Crooks CM, Mirza A, Knight K, Moström MJ, Manuel TD, Sprehe L, Kendall S, Burgt NV, Kowalik TF, Barry PA, Hansen SG, Shu J, Tarantal AF, Chan C, Streblow DN, Picker LJ, Kaur A, Früh K, Permar SR, Malouli D. The pentameric complex is not required for congenital CMV transmission in seronegative rhesus macaques. Sci Transl Med. 2025 Mar 12;17(789):eadm8961. doi: 10.1126/scitranslmed.adm8961. Epub 2025 Mar 12. PMID: 40073152; PMCID: PMC12208562.
Stark A, Crooks CM, Permar SR, Weimer KED. Neonatal Cytomegalovirus Infection: Advocacy, Legislation, and Changing Practice. Clin Perinatol. 2025 Mar;52(1):115-132. doi: 10.1016/j.clp.2024.10.008. Epub 2024 Dec 21. PMID: 39892947.
Miller IG, Mahant AM, Jenks JA, Semmes EC, Rochat E, Herbek SL, Andy C, Rodgers NS, Pollara J, Gerber LM, Herold BC, Permar SR. Influence of Distinct Maternal Cytomegalovirus-Specific Neutralizing and Fc Receptor-Binding Responses on Congenital Cytomegalovirus Transmission in HIV-Exposed Neonates. Viruses. 2025 Feb 26;17(3):325. doi: 10.3390/v17030325. PMID: 40143253; PMCID: PMC11946089.
Serota DE, Crooks CM, McGinty EE, Permar SR, Riley L. Policy strategies for inclusion of pregnant and lactating women in vaccine research. Health Aff Sch. 2025 Feb 19;3(3):qxaf035. doi: 10.1093/haschl/qxaf035. PMID: 40065780; PMCID: PMC11891035.
Manuel T, Moström M, Crooks CM, Davalos A, Barfield R, Scheef E, Kendall S, Midkiff CC, Sprehe L, Trexler M, Boquet F, Shroyer M, Danner V, Doyle-Myers L, Weinbaum C, Mirza A, Lammi S, Otero C, Lee MR, Rogers LW, Granek J, Owzar K, Malouli D, Früh K, Kowalik T, Chan C, Permar SR, Blair RV, Kaur A. A nonhuman primate model mirrors human congenital cytomegalovirus infection and reveals a spectrum of vertical transmission outcomes. bioRxiv [Preprint]. 2025 Jan 21:2025.01.16.633406. doi: 10.1101/2025.01.16.633406. PMID: 40492197; PMCID: PMC12148051.
Permar SR, Schleiss MR, Plotkin SA. A vaccine against cytomegalovirus: how close are we? J Clin Invest. 2025 Jan 2;135(1):e182317. doi: 10.1172/JCI182317. PMID: 39744948; PMCID: PMC11684802.

2024

Karthigeyan KP, Binuya C, Vuong K, Permar SR, Nelson AN. Research on Maternal Vaccination for HIV Prevention. Clin Perinatol. 2024 Dec;51(4):769-782. doi: 10.1016/j.clp.2024.08.007. Epub 2024 Sep 11. PMID: 39487019; PMCID: PMC11531644.
Semmes EC, Nettere DR, Nelson AN, Hurst JH, Cain DW, Burt TD, Kurtzberg J, Reeves RK, Coyne CB, Fouda GG, Pollara J, Permar SR, Walsh KM. In utero human cytomegalovirus infection expands NK-like FcγRIII+ CD8+ T cells that mediate Fc antibody functions. J Clin Invest. 2024 Nov 12:e181342. doi: 10.1172/JCI181342. Epub ahead of print. PMID: 39531313.
Dankwa S, Kosman C, Dennis M, Giorgi EE, Vuong K, Pahountis I, Garza A, Binuya C, McCarthy J, Mayer BT, Ngo JT, Enemuo CA, Carnathan DG, Stanfield-Oakley S, Berendam SJ, Weinbaum C, Engelman K, Magnani DM, Chan C, Ferrari G, Silvestri G, Amara RR, Chahroudi A, Permar SR, Fouda GG, Goswami R. A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions. PLoS One. 2024 Nov 11;19(11):e0312411. doi: 10.1371/journal.pone.0312411. PMID: 39527587; PMCID: PMC11554116.
Jasset OJ, Lopez Zapana PA, Bahadir Z, Shook L, Dennis M, Gilbert E, Liu ZA, Yinger RV, Bald C, Bradford CG, Silfen AH, Klein SL, Pekosz A, Permar S, Konnikova L, Yonker LM, Lauffenburger D, Nelson A, Elovitz MA, Edlow AG. Enhanced placental antibody transfer efficiency with longer interval between maternal RSV vaccination and birth. Am J Obstet Gynecol. 2024 Nov 6:S0002-9378(24)01125-6. doi: 10.1016/j.ajog.2024.10.053. Epub ahead of print. PMID: 39515450.
Alwine J, Goodrum F, Banfield B, Bloom D, Britt WJ, Broadbent AJ, Campos SK, Casadevall A, Chan GC, Cliffe AR, Dermody T, Duprex P, Enquist LW, Frueh K, Geballe AP, Gaglia M, Goldstein S, Greninger AL, Gronvall GK, Jung JU, Kamil JP, Lakdawala S, Liu S-L, Luftig M, Moore JP, Moscona A, Neuman BW, Nikolich JŽ, O’Connor C, Pekosz A, Permar S, Pfeiffer J, Purdy J, Rasmussen A, Semler B, Smith GA, Stein DA, Van Doorslaer K, Weller SK, Whelan SPJ, Yurochko A. The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence. J Virol. 2024 Sep 17;98(9):e0124024. doi: 10.1128/jvi.01240-24. Epub 2024 Aug 1. PMID: 39087765; PMCID: PMC11406950.
Sperling JB, Roth NEW, Welsh WE, McElvaine AT, Permar SR, Gbadegesin RA. Supporting students from underrepresented minority backgrounds in graduate school: A mixed-methods formative study to inform post-baccalaureate design. J Clin Transl Sci. 2024 Sep 16;8(1):e124. doi: 10.1017/cts.2024.590. PMID: 39345705; PMCID: PMC11428063.
Sponholtz MR, Byrne PO, Lee AG, Ramamohan AR, Goldsmith JA, McCool RS, Zhou L, Johnson NV, Hsieh CL, Connors M, Karthigeyan KP, Crooks CM, Fuller AS, Campbell JD, Permar SR, Maynard JA, Yu D, Bottomley MJ, McLellan JS. Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation. Proc Natl Acad Sci U S A. 2024 Sep 10;121(37):e2404250121. doi: 10.1073/pnas.2404250121. Epub 2024 Sep 4. PMID: 39231203; PMCID: PMC11406251.
Williams CA, Murphy EA, Gross M, Herbek S, Mohammed I, Sukhu AC, Salvatore C, Prabhu M, Riley LE, Permar SR, Yang YJ. SARS-CoV-2 Vaccine Elicited Antibody Responses in Human Milk. J Pediatric Infect Dis Soc. 2024 Sep 6:piae086. doi: 10.1093/jpids/piae086. Epub ahead of print. PMID: 39238169.
Mainou E, Berendam SJ, Obregon-Perko V, Uffman EA, Phan CT, Shaw GM, Bar KJ, Kumar MR, Fray EJ, Siliciano JM, Siliciano RF, Silvestri G, Permar SR, Fouda GG, McCarthy J, Chahroudi A, Conway JM, Chan C. Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques. Epidemics. 2024 Sep;48:100780. doi: 10.1016/j.epidem.2024.100780. Epub 2024 Jun 27. PMID: 38964130; PMCID: PMC11518701.
Nelson AN, Shen X, Vekatayogi S, Zhang S, Ozorowski G, Dennis M, Sewall LM, Milligan E, Davis D, Cross KA, Chen Y, van Schooten J, Eudailey J, Isaac J, Memon S, Weinbaum C, Gao H, Stanfield-Oakley S, Byrd A, Chutkan S, Berendam S, Cronin K, Yasmeen A, Alam S, LaBranche CC, Rogers K, Shirreff L, Cupo A, Derking R, Villinger F, Klasse PJ, Ferrari G, Williams WB, Hudgens MG, Ward AB, Montefiori DC, Van Rompay KKA, Wiehe K, Moore JP, Sanders RW, De Paris K, Permar SR. Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques. Sci Immunol. 2024 Aug 30;9(98):eadm7097. doi: 10.1126/sciimmunol.adm7097. Epub 2024 Aug 30. PMID: 39213340.
Hu X, Karthigeyan KP, Herbek S, Valencia SM, Jenks JA, Webster H, Miller IG, Connors M, Pollara J, Andy C, Gerber LM, Walter EB, Edwards KM, Bernstein DI, Hou J, Koch M, Panther L, Carfi A, Wu K, Permar SR. Human Cytomegalovirus mRNA-1647 Vaccine Candidate Elicits Potent and Broad Neutralization and Higher Antibody-Dependent Cellular Cytotoxicity Responses Than the gB/MF59 Vaccine. J Infect Dis. 2024 Aug 16;230(2):455-466. doi: 10.1093/infdis/jiad593. PMID: 38324766; PMCID: PMC11326847.
Woodyear S, Chandler TL, Kawagishi T, Lonergan TM, Patel VA, Williams CA, Permar SR, Ding S, Caddy SL. Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice. Viruses. 2024 Jul 16;16(7):1145. doi: 10.3390/v16071145. PMID: 39066309; PMCID: PMC11281508.
Lantos PM, Gantt S, Janko M, Dionne F, Permar SR, Fowler K. A Geographically Weighted Cost-effectiveness Analysis of Newborn Cytomegalovirus Screening. Open Forum Infect Dis. 2024 Jun 7;11(6):ofae311. doi: 10.1093/ofid/ofae311. PMID: 38933739; PMCID: PMC11200186.
Dalapati T, Williams CA, Giorgi EE, Hurst JH, Herbek S, Chen JL, Kosman C, Rotta AT, Turner NA, Pulido N, Aquino JN, Pfeiffer TS, Rodriguez J, Fouda GG, Permar SR, Kelly MS. Immunogenicity of Monovalent mRNA-1273 and BNT162b2 Vaccines in Children <5 Years of Age. Pediatrics. 2024 Jun 1;153(6):e2024066190. doi: 10.1542/peds.2024-066190. PMID: 38548700; PMCID: PMC11153324.
Nelson A, Lam J, Permar SR, Abramson E. COVID-19 Research Delays Disproportionately Affected Pediatrician-Scientists from Backgrounds Under-Represented in Medicine. J Pediatr. 2024 Jun;269:113865. doi: 10.1016/j.jpeds.2023.113865. Epub 2023 Dec 5. PMID: 38061423; PMCID: PMC11096066.
Rasmussen AL, Gronvall GK, Lowen AC, Goodrum F, Alwine J, Andersen KG, Anthony SJ, Baines J, Banerjee A, Broadbent AJ, Brooke CB, Campos SK, Caposio P, Casadevall A, Chan GC, Cliffe AR, Collins-McMillen D, Connell N, Damania B, Daugherty MD, Debbink K, Dermody TS, DiMaio D, Duprex WP, Emerman M, Galloway DA, Garry RF, Goldstein SA, Greninger AL, Hartman AL, Hogue BG, Horner SM, Hotez PJ, Jung JU, Kamil JP, Karst SM, Laimins L, Lakdawala SS, Landais I, Letko M, Lindenbach B, Liu S-L, Luftig M, McFadden G, Mehle A, Morrison J, Moscona A, Mühlberger E, Munger J, Münger K, Murphy E, Neufeldt CJ, Nikolich JZ, O’Connor CM, Pekosz A, Permar SR, Pfeiffer JK, Popescu SV, Purdy JG, Racaniello VR, Rice CM, Runstadler JA, Sapp MJ, Scott RS, Smith GA, Sorrell EM, Speranza E, Streblow D, Tibbetts SA, Toth Z, Van Doorslaer K, Weiss SR, White EA, White TM, Wobus CE, Worobey M, Yamaoka S, Yurochko A. Virology-the path forward. J Virol. 2024 Jan 23;98(1):e0179123. doi: 10.1128/jvi.01791-23. Epub 2024 Jan 3. Erratum in: J Virol. 2024 Mar 19;98(3):e0007424. doi: 10.1128/jvi.00074-24. PMID: 38168672; PMCID: PMC10804978.
Singh T, Miller IG, Venkatayogi S, Webster H, Heimsath HJ, Eudailey JA, Dudley DM, Kumar A, Mangan RJ, Thein A, Aliota MT, Newman CM, Mohns MS, Breitbach ME, Berry M, Friedrich TC, Wiehe K, O’Connor DH, Permar SR. Prior dengue virus serotype 3 infection modulates subsequent plasmablast responses to Zika virus infection in rhesus macaques. mBio. 2024 Mar 13;15(3):e0316023. doi: 10.1128/mbio.03160-23. Epub 2024 Feb 13. PMID: 38349142; PMCID: PMC10936420.
Wang HY, Li L, Nelson CS, Barfield R, Valencia S, Chan C, Muramatsu H, Lin PJC, Pardi N, An Z, Weissman D, Permar SR. Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth. NPJ Vaccines. 2024 Feb 20;9(1):38. doi: 10.1038/s41541-024-00821-3. PMID: 38378950; PMCID: PMC10879498.
Rasmussen AL, Gronvall GK, Lowen AC, Goodrum F, Alwine J, Andersen KG, Anthony SJ, Baines J, Banerjee A, Broadbent AJ, Brooke CB, Campos SK, Caposio P, Casadevall A, Chan GC, Cliffe AR, Collins-McMillen D, Connell N, Damania B, Daugherty MD, Debbink K, Dermody TS, DiMaio D, Duprex WP, Emerman M, Galloway DA, Garry RF, Goldstein SA, Greninger AL, Hartman AL, Hogue BG, Horner SM, Hotez PJ, Jung JU, Kamil JP, Karst SM, Laimins L, Lakdawala SS, Landais I, Letko M, Lindenbach B, Liu S-L, Luftig M, McFadden G, Mehle A, Morrison J, Moscona A, Mühlberger E, Munger J, Münger K, Murphy E, Neufeldt CJ, Nikolich JZ, O’Connor CM, Pekosz A, Permar SR, Pfeiffer JK, Popescu SV, Purdy JG, Racaniello VR, Rice CM, Runstadler JA, Sapp MJ, Scott RS, Smith GA, Sorrell EM, Speranza E, Streblow D, Tibbetts SA, Toth Z, Van Doorslaer K, Weiss SR, White EA, White TM, Wobus CE, Worobey M, Yamaoka S, Yurochko A. Correction for Rasmussen et al., “Virology-the path forward”. J Virol. 2024 Mar 19;98(3):e0007424. doi: 10.1128/jvi.00074-24. Epub 2024 Feb 9. Erratum for: J Virol. 2024 Jan 23;98(1):e0179123. doi: 10.1128/jvi.01791-23. PMID: 38334328; PMCID: PMC10949460.

2023

Jiang D, Goswami R, Dennis M, Heimsath H, Kozlowski PA, Ardeshir A, Van Rompay KKA, De Paris K, Permar SR, Surana NK. Sutterella and its metabolic pathways positively correlate with vaccine-elicited antibody responses in infant rhesus macaques. Front Immunol. 2023 Dec 6;14:1283343. doi: 10.3389/fimmu.2023.1283343. PMID: 38124733; PMCID: PMC10731017.
Nettere D, Unnithan S, Rodgers N, Nohara J, Cray P, Berry M, Jones C, Armand L, Li SH, Berendam SJ, Fouda GG, Cain DW, Spence TN, Granek JA, Davenport CA, Edwards RJ, Wiehe K, Van Rompay KKA, Moody MA, Permar SR, Pollara J. Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques. NPJ Vaccines. 2023 Nov 24;8(1):183. doi: 10.1038/s41541-023-00775-y. PMID: 38001122; PMCID: PMC10673864.
Otero CE, Barfield R, Scheef E, Nelson CS, Rodgers N, Wang HY, Moström MJ, Manuel TD, Sass J, Schmidt K, Taher H, Papen C, Sprehe L, Kendall S, Davalos A, Barry PA, Früh K, Pollara J, Malouli D, Chan C, Kaur A, Permar SR. Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model. PLoS Pathog. 2023 Oct 23;19(10):e1011378. doi: 10.1371/journal.ppat.1011378. PMID: 37871009; PMCID: PMC10621917.
Valencia SM, Rochat E, Harnois MJ, Dennis M, Webster HS, Hora B, Kumar A, Wang HS, Li L, Freed D, Zhang N, An Z, Wang D, Permar SR. Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection. NPJ Vaccines. 2023 Oct 10;8(1):154. doi: 10.1038/s41541-023-00749-0. PMID: 37816743; PMCID: PMC10564777.
Chandler TL, Yang A, Otero CE, Permar SR, Caddy SL. Protective mechanisms of nonneutralizing antiviral antibodies. PLoS Pathog. 2023 Oct 5;19(10):e1011670. doi: 10.1371/journal.ppat.1011670. PMID: 37796829; PMCID: PMC10553219.
Moström MJ, Yu S, Tran D, Saccoccio FM, Versoza CJ, Malouli D, Mirza A, Valencia S, Gilbert M, Blair RV, Hansen S, Barry P, Früh K, Jensen JD, Pfeifer SP, Kowalik TF, Permar SR, Kaur A. Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection. PLoS Pathog. 2023 Oct 5;19(10):e1011646. doi: 10.1371/journal.ppat.1011646. PMID: 37796819; PMCID: PMC10553354.
Gong Y, Moström M, Otero C, Valencia S, Tarantal AF, Kaur A, Permar SR, Chan C. Mathematical Modeling of Rhesus Cytomegalovirus Transplacental Transmission in Seronegative Rhesus Macaques. Viruses. 2023 Oct 1;15(10):2040. doi: 10.3390/v15102040. PMID: 37896817; PMCID: PMC10611067.
Mahant AM, Trejo FE, Aguilan JT, Sidoli S, Permar SR, Herold BC. Antibody attributes, Fc receptor expression, gestation and maternal SARS-CoV-2 infection modulate HSV IgG placental transfer. iScience. 2023 Aug 15;26(9):107648. doi: 10.1016/j.isci.2023.107648. PMID: 37670782; PMCID: PMC10475509.
Semmes EC, Miller IG, Rodgers N, Phan CT, Hurst JH, Walsh KM, Stanton RJ, Pollara J, Permar SR. ADCC-activating antibodies correlate with decreased risk of congenital human cytomegalovirus transmission. JCI Insight. 2023 Jul 10;8(13):e167768. doi: 10.1172/jci.insight.167768. PMID: 37427588; PMCID: PMC10371338.
Crooks CM, Chan C, Permar SR. Leveraging preclinical study designs to close gaps in vaccine development for perinatal pathogens. J Exp Med. 2023 Jul 3;220(7):e20230184. doi: 10.1084/jem.20230184. Epub 2023 Jun 8. PMID: 37289272; PMCID: PMC10250551.
Toor RK, Semmes EC, Walsh KM, Permar SR, Giulino-Roth L. Does congenital cytomegalovirus infection contribute to the development of acute lymphoblastic leukemia in children? Curr Opin Virol. 2023 Jun;60:101325. doi: 10.1016/j.coviro.2023.101325. Epub 2023 Apr 17. PMID: 37075577.
Ruel T, Penazzato M, Zech JM, Archary M, Cressey TR, Goga A, Harwell J, Landovitz RJ, Lain MG, Lallemant M, Namusoke-Magongo E, Mukui I, Permar SR, Prendergast AJ, Shapiro R, Abrams EJ. Novel Approaches to Postnatal Prophylaxis to Eliminate Vertical Transmission of HIV. Glob Health Sci Pract. 2023 Apr 28;11(2):e2200401. doi: 10.9745/GHSP-D-22-00401. PMID: 37116934; PMCID: PMC10141432.
Rosenberg YJ, Ordonez T, Khanwalkar US, Barnette P, Pandey S, Backes IM, Otero CE, Goldberg BS, Crowley AR, Leib DA, Shapiro MB, Jiang X, Urban LA, Lees J, Hessell AJ, Permar S, Haigwood NL, Ackerman ME. Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates. mBio. 2023 Apr 25;14(2):e0034123. doi: 10.1128/mbio.00341-23. Epub 2023 Mar 22. PMID: 36946726; PMCID: PMC10127586.
Schleiss MR, Permar SR, John CC. What are the key pediatric public policy priorities as the COVID-19 pandemic persists? Pediatr Res. 2023 May;93(6):1451-1455. doi: 10.1038/s41390-023-02529-x. Epub 2023 Feb 25. PMID: 36841882; PMCID: PMC9958307.
Semmes EC, Permar SR. Human Cytomegalovirus Infection Primes Fetal Natural Killer Cells for Fc-Mediated Antiviral Defense. J Infect Dis. 2023 Mar 28;227(6):739-741. doi: 10.1093/infdis/jiac308. PMID: 35876548.
Hansen SG, Womack JL, Perez W, Schmidt KA, Marshall E, Iyer RF, Cleveland Rubeor H, Otero CE, Taher H, Vande Burgt NH, Barfield R, Randall KT, Morrow D, Hughes CM, Selseth AN, Gilbride RM, Ford JC, Caposio P, Tarantal AF, Chan C, Malouli D, Barry PA, Permar SR, Picker LJ, Früh K. Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV. JCI Insight. 2023 Mar 22;8(6):e164692. doi: 10.1172/jci.insight.164692. PMID: 36749635; PMCID: PMC10070102.
Milligan EC, Olstad K, Williams CA, Mallory M, Cano P, Cross KA, Munt JE, Garrido C, Lindesmith L, Watanabe J, Usachenko JL, Hopkins L, Immareddy R, Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Sammak RL, Pollard RE, Yee JL, Herbek S, Scobey T, Miehlke D, Fouda G, Ferrari G, Gao H, Shen X, Kozlowski PA, Montefiori D, Hudgens MG, Edwards DK, Carfi A, Corbett KS, Graham BS, Fox CB, Tomai M, Iyer SS, Baric R, Reader R, Dittmer DP, Van Rompay KKA, Permar SR, De Paris K. Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later. Sci Transl Med. 2023 Mar;15(685):eadd6383. doi: 10.1126/scitranslmed.add6383. Epub 2023 Mar 1. PMID: 36454813; PMCID: PMC9765459.
Prabhu M, Yang YJ, Johnston CD, Murphy EA, Ketas TJ, Diaz-Tapia R, Jurkiewicz M, Racine-Brzostek S, Mohammed I, Sukhu AC, Singh S, Forlenza K, Iyer S, Yee J, Eng D, Marks K, Zhao Z, Klasse PJ, Permar S, Moore JP, Riley LE. Longitudinal antibody response kinetics following SARS-CoV-2 messenger RNA vaccination in pregnant and nonpregnant persons. Am J Obstet Gynecol MFM. 2023 Feb;5(2):100796. doi: 10.1016/j.ajogmf.2022.100796. Epub 2022 Nov 2. PMID: 36334723; PMCID: PMC9626404.
Sass J, Awasthi A, Obregon-Perko V, McCarthy J, Lloyd AL, Chahroudi A, Permar S, Chan C. A simple model for viral decay dynamics and the distribution of infected cell life spans in SHIV-infected infant rhesus macaques. Math Biosci. 2023 Feb;356:108958. doi: 10.1016/j.mbs.2022.108958. Epub 2022 Dec 22. PMID: 36567003; PMCID: PMC9918703.
Jenks JA, Amin S, Sponholtz MR, Kumar A, Wrapp D, Venkatayogi S, Tu JJ, Karthigeyan K, Valencia SM, Connors M, Harnois MJ, Hora B, Rochat E, McLellan JS, Wiehe K, Permar SR. A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus. PLoS Pathog. 2023 Jan 20;19(1):e1011107. doi: 10.1371/journal.ppat.1011107. PMID: 36662906; PMCID: PMC9891502.
Dugdale CM, Ufio O, Alba C, Permar SR, Stranix-Chibanda L, Cunningham CK, Fouda GG, Myer L, Weinstein MC, Leroy V, McFarland EJ, Freedberg KA, Ciaranello AL. Cost-effectiveness of broadly neutralizing antibody prophylaxis for HIV-exposed infants in sub-Saharan African settings. J Int AIDS Soc. 2023 Jan;26(1):e26052. doi: 10.1002/jia2.26052. PMID: 36604316; PMCID: PMC9816086.

2022

Singh T, Hwang KK, Miller AS, Jones RL, Lopez CA, Dulson SJ, Giuberti C, Gladden MA, Miller I, Webster HS, Eudailey JA, Luo K, Von Holle T, Edwards RJ, Valencia S, Burgomaster KE, Zhang S, Mangold JF, Tu JJ, Dennis M, Alam SM, Premkumar L, Dietze R, Pierson TC, Ooi EE, Lazear HM, Kuhn RJ, Permar SR, Bonsignori M. A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization. Cell. 2022 Dec 8;185(25):4826-4840.e17. doi: 10.1016/j.cell.2022.10.023. Epub 2022 Nov 18. PMID: 36402135; PMCID: PMC9742325.
Langel SN, Garrido C, Phan C, Travieso T, Kirshner H, DeMarco T, Ma ZM, Reader JR, Olstad KJ, Sammak RL, Shaan Lakshmanappa Y, Roh JW, Watanabe J, Usachenko J, Immareddy R, Pollard R, Iyer SS, Permar S, Miller LA, Van Rompay KKA, Blasi M. Dam-Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection. Immunohorizons. 2022 Dec 1;6(12):851-863. doi: 10.4049/immunohorizons.2200075. PMID: 36547390; PMCID: PMC10538284.
Anwar IJ, Ezekian B, DeLaura I, Manook M, Schroder P, Yoon J, Curfman V, Branum E, Messina J, Harnois M, Permar SR, Farris AB, Kwun J, Knechtle SJ. Addition of interleukin-6 receptor blockade to carfilzomib-based desensitization in a highly sensitized nonhuman primate model. Am J Transplant. 2022 Dec;22 Suppl 4(Suppl 4):1-11. doi: 10.1111/ajt.17208. PMID: 36239200; PMCID: PMC9722597.
Harnois MJ, Dennis M, Stöhr D, Valencia SM, Rodgers N, Semmes EC, Webster HS, Jenks JA, Barfield R, Pollara J, Chan C, Sinzger C, Permar SR. Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus. J Infect Dis. 2022 Nov 1;226(9):1667-1677. doi: 10.1093/infdis/jiac341. PMID: 35970817; PMCID: PMC10205896.
Mukhopadhyay S, Itell HL, Hartman E, Woodford E, Dhudasia MB, Steppe JT, Valencia S, Roark H, Wade KC, Weimer KED, Permar SR, Puopolo KM. Breast Milk and Saliva for Postnatal Cyto†megalovirus Screening among Very Low Birth Weight Infants. Pediatr Infect Dis J. 2022 Nov 1;41(11):904-910. doi: 10.1097/INF.0000000000003671. Epub 2022 Aug 23. PMID: 36102681.
Hu X, Wang HY, Otero CE, Jenks JA, Permar SR. Lessons from Acquired Natural Immunity and Clinical Trials to Inform Next-Generation Human Cytomegalovirus Vaccine Development. Annu Rev Virol. 2022 Sep 29;9(1):491-520. doi: 10.1146/annurev-virology-100220-010653. Epub 2022 Jun 15. PMID: 35704747; PMCID: PMC10154983.
Chen JL, Fries CN, Berendam SJ, Rodgers NS, Roe EF, Wu Y, Li SH, Jain R, Watts B, Eudailey J, Barfield R, Chan C, Moody MA, Saunders KO, Pollara J, Permar SR, Collier JH, Fouda GG. Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation. Sci Adv. 2022 Sep 23;8(38):eabq0273. doi: 10.1126/sciadv.abq0273. Epub 2022 Sep 23. PMID: 36149967; PMCID: PMC9506727.
Smithgall MC, Murphy EA, Rand S, Sukhu A, Singh S, Schatz-Siemers N, Matrai C, Tu J, Salvatore CM, Prabhu M, Permar S, Riley LE, Robinson BD, Baergen RN, Yang YJ. Placental pathology, neonatal birth weight, and Apgar score in acute and distant SARS-CoV-2 infection. J Clin Transl Res. 2022 Sep 7;8(5):351-359. PMID: 36518545; PMCID: PMC9741934.
Permar SR, Kaur A, Fruh K. Derisking Human Cytomegalovirus Vaccine Clinical Development in Relevant Preclinical Models. J Infect Dis. 2022 Sep 4;226(4):563-565. doi: 10.1093/infdis/jiac131. PMID: 35415750; PMCID: PMC9441196.
Price Rapoza M, McElvaine A, Conroy MB, Okuyemi K, Rouphael N, Teach SJ, Widlansky M, Williams C, Permar SR; National R38 Consortium investigators. Early Outcomes of a New NIH Program to Support Research in Residency. Acad Med. 2022 Sep 1;97(9):1305-1310. doi: 10.1097/ACM.0000000000004643. Epub 2022 Mar 1. PMID: 35234717.
Yang L, Semmes EC, Ovies C, Megli C, Permar S, Gilner JB, Coyne CB. Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface. Elife. 2022 Aug 17;11:e79794. doi: 10.7554/eLife.79794. PMID: 35975985; PMCID: PMC9470165.
Semmes EC, Miller IG, Wimberly CE, Phan CT, Jenks JA, Harnois MJ, Berendam SJ, Webster H, Hurst JH, Kurtzberg J, Fouda GG, Walsh KM, Permar SR. Maternal Fc-mediated non-neutralizing antibody responses correlate with protection against congenital human cytomegalovirus infection. J Clin Invest. 2022 Aug 15;132(16):e156827. doi: 10.1172/JCI156827. PMID: 35763348; PMCID: PMC9374380.
De Paris K, Permar SR. Routine SARS-CoV-2 vaccination for all children. Immunol Rev. 2022 Aug;309(1):90-96. doi: 10.1111/imr.13108. Epub 2022 Jul 7. PMID: 35799475; PMCID: PMC9339529.
Nelson AN, Dennis M, Mangold JF, Li K, Saha PT, Cronin K, Cross KA, Kumar A, Mangan RJ, Shaw GM, Bar KJ, Haynes B, Moody AM, Munir Alam S, Pollara J, Hudgens MG, Van Rompay KKA, De Paris K, Permar SR. Leveraging antigenic seniority for maternal vaccination to prevent mother-to-child transmission of HIV-1. NPJ Vaccines. 2022 Jul 30;7(1):87. doi: 10.1038/s41541-022-00505-w. PMID: 35907918; PMCID: PMC9338948.
Dudley DM, Koenig MR, Stewart LM, Semler MR, Newman CM, Shepherd PM, Yamamoto K, Breitbach ME, Schotzko M, Kohn S, Antony KM, Qiu H, Tunga P, Anderson DM, Guo W, Dennis M, Singh T, Rybarczyk S, Weiler AM, Razo E, Mitzey A, Zeng X, Eickhoff JC, Mohr EL, Simmons HA, Fritsch MK, Mejia A, Aliota MT, Friedrich TC, Golos TG, Kodihalli S, Permar SR, O’Connor DH. Human immune globulin treatment controls Zika viremia in pregnant rhesus macaques. PLoS One. 2022 Jul 14;17(7):e0266664. doi: 10.1371/journal.pone.0266664. PMID: 35834540; PMCID: PMC9282477.
Berendam SJ, Nelson AN, Yagnik B, Goswami R, Styles TM, Neja MA, Phan CT, Dankwa S, Byrd AU, Garrido C, Amara RR, Chahroudi A, Permar SR, Fouda GG. Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure. Front Immunol. 2022 Jul 13;13:885272. doi: 10.3389/fimmu.2022.885272. PMID: 35911681; PMCID: PMC9325996.
Bilgilier C, Schneider M, Kührer K, Kilb N, Hartl R, Topakian T, Kastner MT, Herz T, Nelson CS, Permar SR, Roth G, Steininger C. Heterosubtypic, cross-reactive immunity to human Cytomegalovirus glycoprotein B. Clin Exp Immunol. 2022 Jun 11;208(2):245-254. doi: 10.1093/cei/uxac031. PMID: 35395673; PMCID: PMC9188346.
Tu JJ, Kumar A, Giorgi EE, Eudailey J, LaBranche CC, Martinez DR, Fouda GG, Moreau Y, Thomas A, Montefiori D, Gao F, Sagar M, Permar SR. Vertical HIV-1 Transmission in the Setting of Maternal Broad and Potent Antibody Responses. J Virol. 2022 Jun 8;96(11):e0023122. doi: 10.1128/jvi.00231-22. Epub 2022 May 10. PMID: 35536018; PMCID: PMC9175633.
Lucier A, Fong Y, Li SH, Dennis M, Eudailey J, Nelson A, Saunders K, Cunningham CK, McFarland E, McKinney R, Moody MA, LaBranche C, Montefiori D, Permar SR, Fouda GG. Frequent Development of Broadly Neutralizing Antibodies in Early Life in a Large Cohort of Children With Human Immunodeficiency Virus. J Infect Dis. 2022 May 16;225(10):1731-1740. doi: 10.1093/infdis/jiab629. PMID: 34962990; PMCID: PMC9113503.
Langel SN, Blasi M, Permar SR. Maternal immune protection against infectious diseases. Cell Host Microbe. 2022 May 11;30(5):660-674. doi: 10.1016/j.chom.2022.04.007. PMID: 35550669.
Vijayan KKV, Cross KA, Curtis AD 2nd, Van Rompay KKA, Pollara J, Fox CB, Tomai M, Hanke T, Fouda G, Hudgens MG, Permar SR, De Paris K. Early Post-Vaccination Gene Signatures Correlate With the Magnitude and Function of Vaccine-Induced HIV Envelope-Specific Plasma Antibodies in Infant Rhesus Macaques. Front Immunol. 2022 Apr 27;13:840976. doi: 10.3389/fimmu.2022.840976. PMID: 35572573; PMCID: PMC9094446.
Semmes EC, Li SH, Hurst JH, Yang Z, Niedzwiecki D, Fouda GG, Kurtzberg J, Walsh KM, Permar SR. Congenital Human Cytomegalovirus Infection Is Associated With Decreased Transplacental IgG Transfer Efficiency Due to Maternal Hypergammaglobulinemia. Clin Infect Dis. 2022 Apr 9;74(7):1131-1140. doi: 10.1093/cid/ciab627. PMID: 34260701; PMCID: PMC8994583.
Rouse DJ, Fette LM, Hughes BL, Saade GR, Dinsmoor MJ, Reddy UM, Pass R, Allard D, Mallett G, Clifton RG, Saccoccio FM, Permar SR, Gyamfi-Bannerman C, Varner MW, Goodnight WH, Tita ATN, Costantine MM, Swamy GK, Heyborne KD, Chien EK, Chauhan SP, El-Sayed YY, Casey BM, Parry S, Simhan HN, Napolitano PG, Macones GA; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network. Noninvasive Prediction of Congenital Cytomegalovirus Infection After Maternal Primary Infection. Obstet Gynecol. 2022 Mar 1;139(3):400-406. doi: 10.1097/AOG.0000000000004691. PMID: 35115450; PMCID: PMC8857032.
Gatta LA, Rochat E, Weber JM, Valencia S, Erkanli A, Dotters-Katz SK, Permar S, Hughes BL. Clinical factors associated with cytomegalovirus shedding among seropositive pregnant women. Am J Obstet Gynecol MFM. 2022 Mar;4(2):100560. doi: 10.1016/j.ajogmf.2021.100560. Epub 2022 Jan 4. PMID: 34990874; PMCID: PMC9942897.
Curtis AD 2nd, Saha PT, Dennis M, Berendam SJ, Ramasubramanian P, Cross KA, Alam SM, Ferrari G, Kozlowski PA, Fouda GG, Hudgens MG, Van Rompay KKA, Pollara J, Permar SR, De Paris K. Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection. mSphere. 2022 Feb 23;7(1):e0083921. doi: 10.1128/msphere.00839-21. Epub 2022 Feb 23. PMID: 35196125; PMCID: PMC8865927.
Langel SN, Kelly FL, Brass DM, Nagler AE, Carmack D, Tu JJ, Travieso T, Goswami R, Permar SR, Blasi M, Palmer SM. E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2. Cell Death Discov. 2022 Feb 15;8(1):64. doi: 10.1038/s41420-022-00855-3. PMID: 35169120; PMCID: PMC8847558.
Nguyen-Tran H, Park SW, Messacar K, Dominguez SR, Vogt MR, Permar S, Permaul P, Hernandez M, Douek DC, McDermott AB, Metcalf CJE, Grenfell B, Spaulding AB. Enterovirus D68: a test case for the use of immunological surveillance to develop tools to mitigate the pandemic potential of emerging pathogens. Lancet Microbe. 2022 Feb;3(2):e83-e85. doi: 10.1016/S2666-5247(21)00312-8. Epub 2022 Jan 7. PMID: 35036969; PMCID: PMC8741221.

2021

Berendam SJ, Morgan-Asiedu PK, Mangan RJ, Li SH, Heimsath H, Luo K, Curtis AD 2nd, Eudailey JA, Fox CB, Tomai MA, Phillips B, Itell HL, Kunz E, Hudgens M, Cronin K, Wiehe K, Alam SM, Van Rompay KKA, De Paris K, Permar SR, Moody MA, Fouda GG. Different adjuvanted pediatric HIV envelope vaccines induced distinct plasma antibody responses despite similar B cell receptor repertoires in infant rhesus macaques. PLoS One. 2021 Dec 31;16(12):e0256885. doi: 10.1371/journal.pone.0256885. PMID: 34972105; PMCID: PMC8719683.
Goswami R, Russell VS, Tu JJ, Thomas C, Hughes P, Kelly F, Langel SN, Steppe J, Palmer SM, Haystead T, Blasi M, Permar SR. Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells. iScience. 2021 Dec 17;24(12):103412. doi: 10.1016/j.isci.2021.103412. Epub 2021 Nov 10. PMID: 34786537; PMCID: PMC8579697.
Permar S, Creech CB, Edwards KM, Walter EB. Proposals to Accelerate Novel Vaccine Development for Children. Pediatrics. 2021 Dec 10:e2021054593. doi: 10.1542/peds.2021-054593. Epub ahead of print. PMID: 34889454.
Obregon-Perko V, Bricker KM, Mensah G, Uddin F, Rotolo L, Vanover D, Desai Y, Santangelo PJ, Jean S, Wood JS, Connor-Stroud FC, Ehnert S, Berendam SJ, Liang S, Vanderford TH, Bar KJ, Shaw GM, Silvestri G, Kumar A, Fouda GG, Permar SR, Chahroudi A. Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART. JCI Insight. 2021 Dec 8;6(23):e152526. doi: 10.1172/jci.insight.152526. PMID: 34699383; PMCID: PMC8675190.
Hurst JH, Heston SM, Chambers HN, Cunningham HM, Price MJ, Suarez L, Crew CG, Bose S, Aquino JN, Carr ST, Griffin SM, Smith SH, Jenkins K, Pfeiffer TS, Rodriguez J, DeMarco CT, De Naeyer NA, Gurley TC, Louzao R, Zhao C, Cunningham CK, Steinbach WJ, Denny TN, Lugo DJ, Moody MA, Permar SR, Rotta AT, Turner NA, Walter EB, Woods CW, Kelly MS. Severe Acute Respiratory Syndrome Coronavirus 2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study. Clin Infect Dis. 2021 Nov 2;73(9):e2875-e2882. doi: 10.1093/cid/ciaa1693. PMID: 33141180; PMCID: PMC7665428.
Permar S, Creech CB, Edwards KM, Walter EB. Proposals to Accelerate Novel Vaccine Development for Children. Pediatrics. 2021 Oct 22;149(1):e2021054593. doi: 10.1542/peds.2021-054593. Epub ahead of print. PMID: 34686571; PMCID: PMC9645699.
Garrido C, Hurst JH, Lorang CG, Aquino JN, Rodriguez J, Pfeiffer TS, Singh T, Semmes EC, Lugo DJ, Rotta AT, Turner NA, Burke TW, McClain MT, Petzold EA, Permar SR, Moody MA, Woods CW, Kelly MS, Fouda GG. Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents. JCI Insight. 2021 Sep 8;6(17):e150909. doi: 10.1172/jci.insight.150909. PMID: 34228642; PMCID: PMC8492306.
Schleiss MR, John CC, Permar SR. Children are the key to the Endgame: A case for routine pediatric COVID vaccination. Vaccine. 2021 Sep 7;39(38):5333-5336. doi: 10.1016/j.vaccine.2021.08.005. Epub 2021 Aug 12. PMID: 34393021; PMCID: PMC8358829.
Webster H, Valencia S, Kumar A, Chan C, Dennis M, Roark H, Woods A, John S, Carfi A, Permar SR. Pre-existing immunity to cytomegalovirus in macaques influences human CMV vaccine responses in preclinical models. Vaccine. 2021 Sep 7;39(38):5358-5367. doi: 10.1016/j.vaccine.2021.08.011. Epub 2021 Aug 13. PMID: 34393017.
Fong Y, Permar SR, Tomaras GD. Four-parameter paired response curve for serial dilution assays. J Biopharm Stat. 2021 Sep 3;31(5):634-649. doi: 10.1080/10543406.2021.1931271. Epub 2021 Jun 7. PMID: 34097580; PMCID: PMC8570978.
Weimer KED, Roark H, Fisher K, Cotten CM, Kaufman DA, Bidegain M, Permar SR. Breast Milk and Saliva Lactoferrin Levels and Postnatal Cytomegalovirus Infection. Am J Perinatol. 2021 Aug;38(10):1070-1077. doi: 10.1055/s-0040-1701609. Epub 2020 Feb 18. PMID: 32069486; PMCID: PMC9851802.
Fries CN, Chen JL, Dennis ML, Votaw NL, Eudailey J, Watts BE, Hainline KM, Cain DW, Barfield R, Chan C, Moody MA, Haynes BF, Saunders KO, Permar SR, Fouda GG, Collier JH. HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth. Sci Rep. 2021 Jul 14;11(1):14494. doi: 10.1038/s41598-021-93702-x. PMID: 34262096; PMCID: PMC8280189.
Li M, Brokaw A, Furuta AM, Coler B, Obregon-Perko V, Chahroudi A, Wang HY, Permar SR, Hotchkiss CE, Golos TG, Rajagopal L, Adams Waldorf KM. Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth. Front Genet. 2021 Jul 5;12:680342. doi: 10.3389/fgene.2021.680342. PMID: 34290739; PMCID: PMC8287178.
Marichannegowda MH, Mengual M, Kumar A, Giorgi EE, Tu JJ, Martinez DR, Romero-Severson EO, Li X, Feng L, Permar SR, Gao F. Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection in fetuses. Cell Rep Med. 2021 Jun 16;2(7):100315. doi: 10.1016/j.xcrm.2021.100315. PMID: 34337555; PMCID: PMC8324465.
Garrido C, Curtis AD 2nd, Dennis M, Pathak SH, Gao H, Montefiori D, Tomai M, Fox CB, Kozlowski PA, Scobey T, Munt JE, Mallory ML, Saha PT, Hudgens MG, Lindesmith LC, Baric RS, Abiona OM, Graham B, Corbett KS, Edwards D, Carfi A, Fouda G, Van Rompay KKA, De Paris K, Permar SR. SARS-CoV-2 vaccines elicit durable immune responses in infant rhesus macaques. Sci Immunol. 2021 Jun 15;6(60):eabj3684. doi: 10.1126/sciimmunol.abj3684. PMID: 34131024; PMCID: PMC8774290.
Wang HY, Valencia SM, Pfeifer SP, Jensen JD, Kowalik TF, Permar SR. Common Polymorphisms in the Glycoproteins of Human Cytomegalovirus and Associated Strain-Specific Immunity. Viruses. 2021 Jun 9;13(6):1106. doi: 10.3390/v13061106. PMID: 34207868; PMCID: PMC8227702.
Manook M, Flores WJ, Schmitz R, Fitch Z, Yoon J, Bae Y, Shaw B, Kirk A, Harnois M, Permar S, Farris AB, Magnani DM, Kwun J, Knechtle S. Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model. Front Immunol. 2021 Jun 2;12:660900. doi: 10.3389/fimmu.2021.660900. PMID: 34149698; PMCID: PMC8207189.
Stark A, Cantrell S, Greenberg RG, Permar SR, Weimer KED. Long-term Outcomes after Postnatal Cytomegalovirus Infection in Low Birthweight Preterm Infants: A Systematic Review. Pediatr Infect Dis J. 2021 Jun 1;40(6):571-581. doi: 10.1097/INF.0000000000003072. PMID: 33902071.
McElvaine AT, Hawkins-Salsbury JA, Arora VM, Gladwin MT, Goldenring JR, Huston DP, Krakow D, Rhee K, Solway J, Steinman RA, Towler DA, Utz PJ, Yokoyama WM, Simpson RL, Muglia LJ, Permar SR, Gbadegesin RA. Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative. J Clin Invest. 2021 May 17;131(10):e149948. doi: 10.1172/JCI149948. PMID: 33998594; PMCID: PMC8121502.
Mangold JF, Goswami R, Nelson AN, Martinez DR, Fouda GG, Permar SR. Maternal Intervention to Prevent Mother-to-Child Transmission of HIV: Moving Beyond Antiretroviral Therapy. Pediatr Infect Dis J. 2021 May 1;40(5S):S5-S10. doi: 10.1097/INF.0000000000002774. PMID: 34042904; PMCID: PMC9215267.
Chahroudi A, Permar S. Will We Have the Tools to Address a Reemergent Zika Virus Epidemic? Ann Intern Med. 2021 May;174(5):708-709. doi: 10.7326/M21-0397. Epub 2021 Feb 16. PMID: 33587689.
Kumar A, Giorgi EE, Tu JJ, Martinez DR, Eudailey J, Mengual M, Honnayakanahalli Marichannegowda M, Van Dyke R, Gao F, Permar SR. Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers. PLoS Pathog. 2021 Apr 2;17(4):e1009478. doi: 10.1371/journal.ppat.1009478. PMID: 33798244; PMCID: PMC8055002.
Fries CN, Curvino EJ, Chen JL, Permar SR, Fouda GG, Collier JH. Advances in nanomaterial vaccine strategies to address infectious diseases impacting global health. Nat Nanotechnol. 2021 Apr;16(4):1-14. doi: 10.1038/s41565-020-0739-9. Epub 2020 Aug 17. PMID: 32807876.
D’Agostino EM, Armstrong SC, Humphreys L, Coffman S, Sinclair G, Permar SR, Akinboyo IC. Symptomatic SARS-CoV-2 Transmission in Youth and Staff Attending Day Camps. Pediatrics. 2021 Apr;147(4):e2020042416. doi: 10.1542/peds.2020-042416. Epub 2021 Feb 3. PMID: 33536332.
Itell HL, Berenz A, Mangan RJ, Permar SR, Kaufman DA. Systemic and mucosal levels of lactoferrin in very low birth weight infants supplemented with bovine lactoferrin. Biochem Cell Biol. 2021 Feb;99(1):25-34. doi: 10.1139/bcb-2020-0238. Epub 2020 Aug 25. PMID: 32841570.
Kaufman DA, Berenz A, Itell HL, Conaway M, Blackman A, Nataro JP, Permar SR. Dose escalation study of bovine lactoferrin in preterm infants: getting the dose right. Biochem Cell Biol. 2021 Feb;99(1):7-13. doi: 10.1139/bcb-2020-0217. Epub 2020 Aug 26. PMID: 32846100.
Semmes EC, Chen JL, Goswami R, Burt TD, Permar SR, Fouda GG. Understanding Early-Life Adaptive Immunity to Guide Interventions for Pediatric Health. Front Immunol. 2021 Jan 21;11:595297. doi: 10.3389/fimmu.2020.595297. PMID: 33552052; PMCID: PMC7858666.
Berendam SJ, Styles TM, Morgan-Asiedu PK, Tenney D, Kumar A, Obregon-Perko V, Bar KJ, Saunders KO, Santra S, De Paris K, Tomaras GD, Chahroudi A, Permar SR, Amara RR, Fouda GG. Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses. J Virol. 2021 Jan 13;95(3):e01667-20. doi: 10.1128/JVI.01667-20. PMID: 33177194; PMCID: PMC7925105.

Place

2025

Place NJ, Price PL, Henry ME. Two different immunoassays produced highly discordant results when used to measure anti-Müllerian hormone in feline blood serum and urine. J Vet Diagn Invest. 2025 Nov;37(6):927-932. doi: 10.1177/10406387251373083. Epub 2025 Sep 20. PMID: 40974248; PMCID: PMC12450206.
Pinn-Woodcock TL, Llanos-Soto SG, Ivanek R, Goodrich E, Frye E, Wells A, Mullen K, Arbittier E, Hughes L, Berryhill E, Brosnahan P, Buslinger L, Schnabel L, DeNotta S, Mallicote M, Peek S, Place NJ. Seasonal elevation in equine adrenocorticotropic hormone occurs throughout the contiguous United States and is influenced by latitude and age. J Am Vet Med Assoc. 2025 Aug 1;263(11):1380-1389. doi: 10.2460/javma.25.04.0223. PMID: 40749730.
Bovell RTM, Comizzoli P, Nagashima JB, Santiestevan J, Crosier AE, Place NJ. Anti-Müllerian hormone concentration measured before gonadotropin stimulation is associated with quality of subsequent ovarian response in the cheetah (Acinonyx jubatus) and domestic cat (Felis catus)†. Biol Reprod. 2025 Apr 13;112(4):754-766. doi: 10.1093/biolre/ioaf025. PMID: 39903683.

2024

Josefson CC, Fitzwater BM, Beltran RS, Costa DP, Fornara JH, Garland T Jr, Harris BN, Hinde K, Hood WR, Hunt E, Kenagy GJ, Liebl AL, Litmer AR, Lopes PC, Misra D, Meuti M, Place NJ, Powers LE, Saltzman W, Orr TJ. Balancing Act: An Interdisciplinary Exploration of Trade-offs in Reproducing Females. Integr Comp Biol. 2024 Dec 20;64(6):1734-1756. doi: 10.1093/icb/icae092. PMID: 38982258.
Place NJ, Peck DT. Testing the Adaptive Sterilization Hypothesis in Mice Inoculated with Chlamydia muridarum. Integr Comp Biol. 2024 Dec 20;64(6):1661-1666. doi: 10.1093/icb/icae010. PMID: 38587825.
Conley AJ, Berger T, Caruso CJ, Cotterman RF, Jones T, Christensen BW, Hollinshead FK, Place NJ. Population-based anti-Müllerian hormone reference intervals help define gonadal status in the bitch. J Am Vet Med Assoc. 2024 Sep 11:1-8. doi: 10.2460/javma.24.06.0405. Epub ahead of print. PMID: 39260407.
Josefson CC, Fitzwater BM, Beltran RS, Costa DP, Fornara JH, Garland T Jr, Harris BN, Hinde K, Hood WR, Hunt E, Kenagy GJ, Liebl AL, Litmer AR, Lopes PC, Misra D, Meuti M, Place NJ, Powers LE, Saltzman W, Orr TJ. Balancing Act: an Interdisciplinary Exploration of Trade-offs in Reproducing Females. Integr Comp Biol. 2024 Jul 9:icae092. doi: 10.1093/icb/icae092. Epub ahead of print. PMID: 38982258.
Place NJ, Peck DT. Testing the Adaptive Sterilization Hypothesis in mice inoculated with Chlamydia muridarum. Integr Comp Biol. 2024 Apr 8:icae010. doi: 10.1093/icb/icae010. Epub ahead of print. PMID: 38587825.

2023

Prieto JM, Carney PC, Smith SM, Miller ML, Rishniw M, Randolph JF, Salerno VJ, Lamb SV, Place NJ, Farace G, Peterson S, Peterson ME. Biological variation of serum thyrotropin and thyroid hormones concentrations determined at 8-week intervals for 1 year in clinically healthy cats. Vet Clin Pathol. 2023 Sep;52(3):493-502. doi: 10.1111/vcp.13251. Epub 2023 Aug 1. PMID: 37528445.
Brieño-Enríquez MA, Faykoo-Martinez M, Goben M, Grenier JK, McGrath A, Prado AM, Sinopoli J, Wagner K, Walsh PT, Lopa SH, Laird DJ, Cohen PE, Wilson MD, Holmes MM, Place NJ. Postnatal oogenesis leads to an exceptionally large ovarian reserve in naked mole-rats. Nat Commun. 2023 Feb 21;14(1):670. doi: 10.1038/s41467-023-36284-8. PMID: 36810851; PMCID: PMC9944903.

2022

McCormick SK, Holekamp KE, Smale L, Weldele ML, Glickman SE, Place NJ. Sex Differences in Spotted Hyenas. Cold Spring Harb Perspect Biol. 2022 Jun 14;14(6):a039180. doi: 10.1101/cshperspect.a039180. PMID: 34649923; PMCID: PMC9248831.
Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, Friedlander G, Gibney PA, Gorbunova V, Hine C, Holmes MM, Jarvis JUM, Kawamura Y, Kutsukake N, Kenyon C, Khaled WT, Kikusui T, Kissil J, Lagestee S, Larson J, Lauer A, Lavrenchenko LA, Lee A, Levitt JB, Lewin GR, Lewis Hardell KN, Lin TD, Mason MJ, McCloskey D, McMahon M, Miura K, Mogi K, Narayan V, O’Connor TP, Okanoya K, O’Riain MJ, Park TJ, Place NJ, Podshivalova K, Pamenter ME, Pyott SJ, Reznick J, Ruby JG, Salmon AB, Santos-Sacchi J, Sarko DK, Seluanov A, Shepard A, Smith M, Storey KB, Tian X, Vice EN, Viltard M, Watarai A, Wywial E, Yamakawa M, Zemlemerova ED, Zions M, Smith ESJ. The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole-rat biology. Biol Rev Camb Philos Soc. 2022 Feb;97(1):115-140. doi: 10.1111/brv.12791. Epub 2021 Sep 3. PMID: 34476892; PMCID: PMC9277573.

2021

Place NJ, Prado AM, Faykoo-Martinez M, Brieño-Enriquez MA, Albertini DF, Holmes MM. Germ cell nests in adult ovaries and an unusually large ovarian reserve in the naked mole-rat. Reproduction. 2021 Jan;161(1):89-98. doi: 10.1530/REP-20-0304. PMID: 33151901; PMCID: PMC7770031.

Ren

2025

Favakeh A, Mokhtare A, Zhang H, Ren YA, Abbaspourrad A. On-chip oocyte cumulus removal using vibration-induced flow. Lab Chip. 2025 Oct 22;25(21):5551-5562. doi: 10.1039/d5lc00414d. PMID: 40977337.
Zhang H, Dhillon J, Soloway PD, Shui B, Lee S, Grenier JK, Munn PR, Ljungberg MC, Williams RB, Lanz RB, Liao YH, Ren YA. Semaphorin 3E-Plexin-D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice. Adv Sci (Weinh). 2025 Aug;12(29):e17163. doi: 10.1002/advs.202417163. Epub 2025 May 20. PMID: 40391781; PMCID: PMC12362816.
Zhang H, Lanz RB, Dhillon J, Soloway PD, Shui B, Ren YA. CCAAT/Enhancer-Binding Proteins α and β Regulate Ovulation and Gene Expression via Dose- and Stage-Dependent Mechanisms. Endocrinology. 2025 May 19;166(7):bqaf081. doi: 10.1210/endocr/bqaf081. PMID: 40294160; PMCID: PMC12086141.

2024

Chang WJ, Baker MS, Laritsky E, Gunasekara CJ, Maduranga U, Galliou JC, McFadden JW, Waltemyer JR, Berggren-Thomas B, Tate BN, Zhang H, Rosen BD, Van Tassell CP, Liu GE, Coarfa C, Ren YA, Waterland RA. Systemic interindividual DNA methylation variants in cattle share major hallmarks with those in humans. Genome Biol. 2024 Jul 15;25(1):185. doi: 10.1186/s13059-024-03307-6. PMID: 39004763; PMCID: PMC11247883.
Mantri M, Zhang HH, Spanos E, Ren YA, De Vlaminck I. A spatiotemporal molecular atlas of the ovulating mouse ovary. Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2317418121. doi: 10.1073/pnas.2317418121. Epub 2024 Jan 22. PMID: 38252830; PMCID: PMC10835069.

Rizzuto

2025

Oh JH, Rizzuto G, Elkin R, Weistuch C, Norton L, Dveksler G, Deasy JO. Pregnancy-specific glycoproteins as potential drug targets for female lung adenocarcinoma patients. Brief Funct Genomics. 2025 Jan 15;24. doi: 10.1093/bfgp/elaf004. PubMed PMID: 40257008; PubMed Central PMCID: PMC12010166.
Rizzuto G. B Cell Responses to the Placenta and Fetus. Annu Rev Pathol. 2025 Jan;20(1):33-58. doi: 10.1146/annurev-pathmechdis-111523-023459. Epub 2025 Jan 2. Review. PubMed PMID: 39264989; PubMed Central PMCID: PMC11912550.
Liu YL, Praiss AM, Chiang S, Devereaux K, Huang J, Rizzuto G, Al-Rawi D, Weigelt B, Jewell E, Abu-Rustum NR, Aghajanian C. Gestational trophoblastic neoplasm: Patient outcomes and clinical pearls from a multidisciplinary referral center. Gynecol Oncol. 2025 Jan;192:171-177. doi: 10.1016/j.ygyno.2024.12.009. Epub 2024 Dec 13. PubMed PMID: 39674133; PubMed Central PMCID: PMC11761376.

2023

Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik CR, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. Validation of a murine proteome-wide phage display library for identification of autoantibody specificities. JCI Insight. 2023 Dec 8;8(23). doi: 10.1172/jci.insight.174976. PubMed PMID: 37934865; PubMed Central PMCID: PMC10795829.
Haber LA, Dhaliwal G, Lo L, Rizzuto G. Evaluating a low anion gap: A practical approach. Cleve Clin J Med. 2023 Oct 2;90(10):619-623. doi: 10.3949/ccjm.90a.23035. Review. PubMed PMID: 37783490; PubMed Central PMCID: PMC11924111.
Greenbaum S, Averbukh I, Soon E, Rizzuto G, Baranski A, Greenwald NF, Kagel A, Bosse M, Jaswa EG, Khair Z, Kwok S, Warshawsky S, Piyadasa H, Goldston M, Spence A, Miller G, Schwartz M, Graf W, Van Valen D, Winn VD, Hollmann T, Keren L, van de Rijn M, Angelo M. A spatially resolved timeline of the human maternal-fetal interface. Nature. 2023 Jul;619(7970):595-605. doi: 10.1038/s41586-023-06298-9. Epub 2023 Jul 19. PubMed PMID: 37468587; PubMed Central PMCID: PMC10356615.
Glasner A, Rose SA, Sharma R, Gudjonson H, Chu T, Green JA, Rampersaud S, Valdez IK, Andretta ES, Dhillon BS, Schizas M, Dikiy S, Mendoza A, Hu W, Wang ZM, Chaudhary O, Xu T, Mazutis L, Rizzuto G, Quintanal-Villalonga A, Manoj P, de Stanchina E, Rudin CM, Pe’er D, Rudensky AY. Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies. Nat Immunol. 2023 Jun;24(6):1020-1035. doi: 10.1038/s41590-023-01504-2. Epub 2023 May 1. PubMed PMID: 37127830; PubMed Central PMCID: PMC10232368.
Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik C, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities. bioRxiv. 2023 Apr 7;. doi: 10.1101/2023.04.07.535899. PubMed PMID: 37066405; PubMed Central PMCID: PMC10104109.
Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nat Immunol. 2023 Apr;24(4):676-689. doi: 10.1038/s41590-023-01444-x. Epub 2023 Mar 13. PubMed PMID: 36914891; PubMed Central PMCID: PMC10063449.

2022

Rizzuto G, Erlebacher A. Trophoblast antigens, fetal blood cell antigens, and the paradox of fetomaternal tolerance. J Exp Med. 2022 May 2;219(5). doi: 10.1084/jem.20211515. Epub 2022 Apr 13. PubMed PMID: 35416936; PubMed Central PMCID: PMC9011327.
Rizzuto G, Brooks JF, Tuomivaara ST, McIntyre TI, Ma S, Rideaux D, Zikherman J, Fisher SJ, Erlebacher A. Establishment of fetomaternal tolerance through glycan-mediated B cell suppression. Nature. 2022 Mar;603(7901):497-502. doi: 10.1038/s41586-022-04471-0. Epub 2022 Mar 2. PubMed PMID: 35236989; PubMed Central PMCID: PMC9592526.

2021

Hirschhorn D, Betof Warner A, Maniyar R, Chow A, Mangarin LM, Cohen AD, Hamadene L, Rizzuto GA, Budhu S, Suek N, Liu C, Houghton AN, Merghoub T, Wolchok JD. Cyclophosphamide enhances the antitumor potency of GITR engagement by increasing oligoclonal cytotoxic T cell fitness. JCI Insight. 2021 Oct 22;6(20). doi: 10.1172/jci.insight.151035. PubMed PMID: 34676831; PubMed Central PMCID: PMC8564916.
Castel P, Dharmaiah S, Sale MJ, Messing S, Rizzuto G, Cuevas-Navarro A, Cheng A, Trnka MJ, Urisman A, Esposito D, Simanshu DK, McCormick F. RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity. Proc Natl Acad Sci U S A. 2021 Aug 17;118(33). doi: 10.1073/pnas.2103261118. PubMed PMID: 34380736; PubMed Central PMCID: PMC8379911.

Schimenti

2025

Singh V, Schimenti JC. Relevance, strategies, and added value of mouse models in androgenetics. Andrology. 2025 Jul;13(5):1158-1169. doi: 10.1111/andr.13761. Epub 2024 Sep 19. PMID: 39300831.
James RC, Wang JK, Bhatt SR, Shadid SE, Phuong DJ, Schimenti JC. Embryonic Stem Cell-Specific Responses to DNA Replication Stress. bioRxiv [Preprint]. 2025 May 18:2025.05.16.654332. doi: 10.1101/2025.05.16.654332. PMID: 40463205; PMCID: PMC12132374.
Li L, Ding X, Sheft AP, Schimenti JC. WITHDRAWN: High throughput CRISPR perturbation screens identify epigenetic regulators impacting primordial germ cell development. bioRxiv [Preprint]. 2025 May 13:2024.02.26.582097. doi: 10.1101/2024.02.26.582097. PMID: 38463983; PMCID: PMC10925113.
Munisha M, Huang R, Khan J, Schimenti JC. Chronic replication stress-mediated genomic instability disrupts placenta development in mice. bioRxiv [Preprint]. 2025 May 12:2025.02.28.640689. doi: 10.1101/2025.02.28.640689. PMID: 40093167; PMCID: PMC11908151.
Phuong DJ, Ralston CQ, Ezzat TM, Ashe CS, Armstrong AP, Flesken-Nikitin A, Yamulla RJ, Nikitin AY, Schimenti JC. Combinatorial organoid mutagenesis screen reveals gene constellations driving malignant transformation, pathology and chemosensitivity in high-grade serous ovarian carcinoma. bioRxiv [Preprint]. 2025 May 11:2025.03.10.642422. doi: 10.1101/2025.03.10.642422. PMID: 40654781; PMCID: PMC12248148.
Li L, Gao J, Yi D, Sheft AP, Schimenti JC, Ding X. Scalable primordial germ cell-like-cell platform for functional genomics identifies epigenetic fertility modifiers. bioRxiv [Preprint]. 2025 May 2:2024.02.15.580543. doi: 10.1101/2024.02.15.580543. PMID: 38405756; PMCID: PMC10888945.
Phuong DJ, Pirtz MG, Ralston CQ, Cosgrove BD, Schimenti JC, Flesken-Nikitin A, Nikitin AY. Aggressive Serous Carcinomas of the Female Reproductive Tract: Cancer-Prone Cell States and Genetic Drivers. Cancers (Basel). 2025 Feb 11;17(4):604. doi: 10.3390/cancers17040604. PMID: 40002199; PMCID: PMC11852459.

2024

Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Author Correction: Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Nov 20;15(1):10053. doi: 10.1038/s41467-024-54465-x. Erratum for: Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39567528; PMCID: PMC11579345.
Flesken-Nikitin A, Ralston CQ, Fu DJ, De Micheli AJ, Phuong DJ, Harlan BA, Ashe CS, Armstrong AP, McKellar DW, Ghuwalewala S, Ellenson LH, Schimenti JC, Cosgrove BD, Nikitin AY. Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma. Nat Commun. 2024 Oct 5;15(1):8641. doi: 10.1038/s41467-024-52984-1. PMID: 39366996; PMCID: PMC11452611.
Singh V, Schimenti JC. Relevance, strategies, and added value of mouse models in androgenetics. Andrology. 2024 Sep 19. doi: 10.1111/andr.13761. Epub ahead of print. PMID: 39300831.
Gao J, Qin Y, Schimenti JC. Gene regulation during meiosis. Trends Genet. 2024 Apr;40(4):326-336. doi: 10.1016/j.tig.2023.12.006. Epub 2024 Jan 4. PMID: 38177041; PMCID: PMC11003842.

2023

Hung YH, Capeling M, Villanueva JW, Kanke M, Shanahan MT, Huang S, Cubitt R, Rinaldi VD, Schimenti JC, Spence JR, Sethupathy P. Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model. BMC Genomics. 2023 Oct 26;24(1):641. doi: 10.1186/s12864-023-09743-1. PMID: 37884859; PMCID: PMC10601309.
Williams RM, Bloom JC, Robertus CM, Recknagel AK, Putnam D, Schimenti JC, Zipfel WR. Practical strategies for robust and inexpensive imaging of aqueous-cleared tissues. J Microsc. 2023 Sep;291(3):237-247. doi: 10.1111/jmi.13213. Epub 2023 Jul 11. PMID: 37413663.
Ding X, Singh P, Schimenti K, Tran TN, Fragoza R, Hardy J, Orwig KE, Olszewska M, Kurpisz MK, Yatsenko AN, Conrad DF, Yu H, Schimenti JC. In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2219925120. doi: 10.1073/pnas.2219925120. Epub 2023 Jul 17. PMID: 37459509; PMCID: PMC10372637.
Ding X, Schimenti JC. Female infertility from oocyte maturation arrest: assembling the genetic puzzle. EMBO Mol Med. 2023 Jun 7;15(6):e17729. doi: 10.15252/emmm.202317729. Epub 2023 Apr 19. PMID: 37073822; PMCID: PMC10245026.

2022

Schimenti JC, Huang R, Li L, James R. Genome Maintenance in Mammalian Stem Cells. Annu Rev Genet. 2022 Nov 30;56:145-164. doi: 10.1146/annurev-genet-072920-022154. Epub 2022 Aug 17. PMID: 35977408.
Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, Tran TN, Neve RL, Roper RJ, Brennand KJ, Roussos P, Schimenti JC, Friedman AK, Shen L, Blitzer RD, Robison AJ, Crabtree GR, Maze I. Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nat Commun. 2022 Oct 26;13(1):6384. doi: 10.1038/s41467-022-34200-0. PMID: 36289231; PMCID: PMC9606253.
Rooney AM, Ayobami OO, Kelly NH, Schimenti JC, Ross FP, van der Meulen MCH. Bone mass and adaptation to mechanical loading are sexually dimorphic in adult osteoblast-specific ERα knockout mice. Bone. 2022 May;158:116349. doi: 10.1016/j.bone.2022.116349. Epub 2022 Feb 3. PMID: 35123146.

2021

Munisha M, Schimenti JC. Genome maintenance during embryogenesis. DNA Repair (Amst). 2021 Oct;106:103195. doi: 10.1016/j.dnarep.2021.103195. Epub 2021 Jul 29. PMID: 34358805.
Singh P, Fragoza R, Blengini CS, Tran TN, Pannafino G, Al-Sweel N, Schimenti KJ, Schindler K, Alani EA, Yu H, Schimenti JC. Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging. Nat Commun. 2021 Aug 18;12(1):5005. doi: 10.1038/s41467-021-25028-1. PMID: 34408140; PMCID: PMC8373927.
Ding X, Schimenti JC. Strategies to Identify Genetic Variants Causing Infertility. Trends Mol Med. 2021 Aug;27(8):792-806. doi: 10.1016/j.molmed.2020.12.008. Epub 2021 Jan 8. PMID: 33431240; PMCID: PMC8263794.
Gao P, Lyu Q, Ghanam AR, Lazzarotto CR, Newby GA, Zhang W, Choi M, Slivano OJ, Holden K, Walker JA 2nd, Kadina AP, Munroe RJ, Abratte CM, Schimenti JC, Liu DR, Tsai SQ, Long X, Miano JM. Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression. Genome Biol. 2021 Mar 16;22(1):83. doi: 10.1186/s13059-021-02304-3. PMID: 33722289; PMCID: PMC7962346.
Schimenti JC. Conditional surrender in one generation: determining the reproductive roles of mouse embryo lethal genes by embryo complementation. Biol Reprod. 2021 Jan 4;104(1):8-10. doi: 10.1093/biolre/ioaa193. PMID: 33057575.

Seandel

2023

Luo Y, Yamada M, N’Tumba-Byn T, Asif H, Gao M, Hu Y, Marangoni P, Liu Y, Evans T, Rafii S, Klein OD, Voss HU, Hadjantonakis AK, Elemento O, Martin LA, Seandel M. SPRY4-dependent ERK negative feedback demarcates functional adult stem cells in the male mouse germline†. Biol Reprod. 2023 Oct 13;109(4):533-551. doi: 10.1093/biolre/ioad089. PMID: 37552049; PMCID: PMC10577279.
Yamada M, Luo Y, Seandel M. Viral Transduction of Mammalian Spermatogonial Stem Cells. Methods Mol Biol. 2023;2656:211-225. doi: 10.1007/978-1-0716-3139-3_12. PMID: 37249874.

Selvaraj

2025

Koganti PP, Zhao AH, Kern MC, Fassinou ACR, Selvaraj V. STAR/STARD1: A mitochondrial intermembrane space cholesterol shuttle degraded through mitophagy. Proc Natl Acad Sci U S A. 2025 Oct 14;122(41):e2508809122. doi: 10.1073/pnas.2508809122. Epub 2025 Oct 7. PMID: 41055982; PMCID: PMC12541442.
Zhao AH, Koganti PP, Qian M, Garcia A, O’Day P, Auchus RJ, Covey DF, Selvaraj V. Target validation uncouples TSPO from 19-Atriol-mediated inhibition of steroidogenesis and reveals true enzymatic targets. bioRxiv [Preprint]. 2025 Sep 25:2025.09.25.678677. doi: 10.1101/2025.09.25.678677. PMID: 41040383; PMCID: PMC12485943.
Smith CR, Tu LN, Koganti PP, Selvaraj V. TSPO deficiency reveals a novel role for porphyrins in regulating white adipose tissue lipid metabolism. bioRxiv [Preprint]. 2025 Sep 17:2025.09.14.676078. doi: 10.1101/2025.09.14.676078. PMID: 41000793; PMCID: PMC12458925.
Vijayan Pillai V, Koganti PP, Gurung S, Cheong SH, Selvaraj V. Transformed bovine trophoblast stem cell lines, characterization, gene editing and secretions. Biol Reprod. 2025 Sep 13:ioaf212. doi: 10.1093/biolre/ioaf212. Epub ahead of print. PMID: 40971496.
Koganti PP, Selvaraj V. Single cell resolution of neurosteroidogenesis in the murine brain: de novo biosynthesis. J Endocrinol. 2025 May 7;265(3):e240318. doi: 10.1530/JOE-24-0318. PMID: 40261711; PMCID: PMC12377410.
Koganti PP, Selvaraj V. Single cell resolution of neurosteroidogenesis in the murine brain: intermediary biosynthesis. J Endocrinol. 2025 May 7;265(3):e240333. doi: 10.1530/JOE-24-0333. PMID: 40261706; PMCID: PMC12413686.
Koganti PP, Zhao AH, Kern MC, Fassinou ACR, Selvaraj V. STAR/STARD1: a mitochondrial intermembrane space cholesterol shuttle degraded through mitophagy. bioRxiv [Preprint]. 2025 Apr 10:2025.04.03.647084. doi: 10.1101/2025.04.03.647084. Update in: Proc Natl Acad Sci U S A. 2025 Oct 14;122(41):e2508809122. doi: 10.1073/pnas.2508809122. PMID: 40236021; PMCID: PMC11996515.

2024

Selvaraj V, Won E. Transforming aquaculture with insect-based feed: restraining factors. Anim Front. 2024 Sep 5;14(4):24-27. doi: 10.1093/af/vfae011. PMID: 39246843; PMCID: PMC11377066.
Schalich KM, Koganti PP, Castillo JM, Reiff OM, Cheong SH, Selvaraj V. The uterine secretory cycle: recurring physiology of endometrial outputs that setup the uterine luminal microenvironment. Physiol Genomics. 2024 Jan 1;56(1):74-97. doi: 10.1152/physiolgenomics.00035.2023. Epub 2023 Sep 11. PMID: 37694291.

2023

Sushadi PS, Kuwabara M, Maung EEW, Mohamad Mohtar MS, Sakamoto K, Selvaraj V, Asano A. Arresting calcium-regulated sperm metabolic dynamics enables prolonged fertility in poultry liquid semen storage. Sci Rep. 2023 Dec 8;13(1):21775. doi: 10.1038/s41598-023-48550-2. PMID: 38066036; PMCID: PMC10709635.

2022

Koganti PP, Tu LN, Selvaraj V. Functional metabolite reserves and lipid homeostasis revealed by the MA-10 Leydig cell metabolome. PNAS Nexus. 2022 Sep 27;1(4):pgac215. doi: 10.1093/pnasnexus/pgac215. PMID: 36714831; PMCID: PMC9802464.
Jimenez IA, Stilin AP, Morohaku K, Hussein MH, Koganti PP, Selvaraj V. Mitochondrial translocator protein deficiency exacerbates pathology in acute experimental ulcerative colitis. Front Physiol. 2022 Aug 19;13:896951. doi: 10.3389/fphys.2022.896951. PMID: 36060674; PMCID: PMC9437295.
Koganti PP, Zhao AH, Selvaraj V. Exogenous cholesterol acquisition signaling in LH-responsive MA-10 Leydig cells and in adult mice. J Endocrinol. 2022 Aug 17;254(3):187-199. doi: 10.1530/JOE-22-0043. PMID: 35900012; PMCID: PMC9840751.
Bishop CV, Selvaraj V, Townson DH, Pate JL, Wiltbank MC. History, insights, and future perspectives on studies into luteal function in cattle. J Anim Sci. 2022 Jul 1;100(7):skac143. doi: 10.1093/jas/skac143. PMID: 35772753; PMCID: PMC9246667.
Schalich KM, Selvaraj V. Contradictions on colostrum IgG levels and Brix values are real and can be explained. Response to letter by Lombard et al. (2022). J Anim Sci. 2022 Apr 1;100(4):skac120. doi: 10.1093/jas/skac120. PMID: 35483038; PMCID: PMC9049248.
Pillai VV, Kei TG, Gurung S, Das M, Siqueira LGB, Cheong SH, Hansen PJ, Selvaraj V. RhoA/ROCK signaling antagonizes bovine trophoblast stem cell self-renewal and regulates preimplantation embryo size and differentiation. Development. 2022 Apr 1;149(7):dev200115. doi: 10.1242/dev.200115. Epub 2022 Mar 31. PMID: 35297991.

2021

Pillai VV, Koganti PP, Kei TG, Gurung S, Butler WR, Selvaraj V. Efficient induction and sustenance of pluripotent stem cells from bovine somatic cells. Biol Open. 2021 Oct 15;10(10):bio058756. doi: 10.1242/bio.058756. Epub 2021 Nov 1. PMID: 34719702; PMCID: PMC8565620.
Schalich KM, Reiff OM, Nguyen BT, Lamb CL, Mondoza CR, Selvaraj V. Temporal kinetics of bovine mammary IgG secretion into colostrum and transition milk. J Anim Sci. 2021 May 1;99(5):skab083. doi: 10.1093/jas/skab083. PMID: 33715013; PMCID: PMC8139318.

Smith-Raska

2024

Richter F, Rutherford KD, Cooke AJ, Meshkati M, Eddy-Abrams V, Greene D, Kosowsky J, Park Y, Aggarwal S, Burke RJ, Chang W, Connors J, Giannone PJ, Hays T, Khattar D, Polak M, Senaldi L, Smith-Raska M, Sridhar S, Steiner L, Swanson JR, Tauber KA, Barbosa M, Guttmann KF, Turro E. A Deep Intronic PKHD1 Variant Identified by SpliceAI in a Deceased Neonate With Autosomal Recessive Polycystic Kidney Disease. Am J Kidney Dis. 2024 Jun;83(6):829-833. doi: 10.1053/j.ajkd.2023.12.011. Epub 2024 Jan 10. PMID: 38211685; PMCID: PMC11116050.

2021

Cullen SM, Hassan N, Smith-Raska M. Erratum to: Effects of noninherited ancestral genotypes on offspring phenotypes. Biol Reprod. 2021 Nov 15;105(5):1365. doi: 10.1093/biolre/ioab167. Erratum for: Biol Reprod. 2021 Sep 14;105(3):747-760. doi: 10.1093/biolre/ioab120. PMID: 34515296.
Cullen SM, Hassan N, Smith-Raska M. Effects of noninherited ancestral genotypes on offspring phenotypes†. Biol Reprod. 2021 Sep 14;105(3):747-760. doi: 10.1093/biolre/ioab120. Erratum in: Biol Reprod. 2021 Nov 15;105(5):1365. doi: 10.1093/biolre/ioab167. PMID: 34159361.

Smolka

2025

Yang C, Du H, Lee GB, Uematsu M, He W, Doré E, Yu W, Sanford EJ, Smolka MB, Boilard E, Baskin JM, Hao L, Hu F. sPLA2-IIA modifies progranulin deficiency phenotypes in mouse models. Mol Neurodegener. 2025 Jun 17;20(1):72. doi: 10.1186/s13024-025-00863-8. PMID: 40528203; PMCID: PMC12175356.
Cao Y, Wang Y, Badar J, Palek M, Jaber K, Faça VM, Huang TC, Çelik E, Macurek L, Smolka MB. An ATM-PPM1D Circuit Controls the Processing and Restart of DNA Replication Forks. bioRxiv [Preprint]. 2025 May 15:2025.05.13.652823. doi: 10.1101/2025.05.13.652823. PMID: 40462982; PMCID: PMC12132398.
Smolka M, Comstock W, Navarro M, Maybee D, Rho Y, Wagner M, Wang Y. Proteomic Sensors for Quantitative, Multiplexed and Spatial Monitoring of Kinase Signaling. Res Sq [Preprint]. 2025 Mar 27:rs.3.rs-6220494. doi: 10.21203/rs.3.rs-6220494/v1. PMID: 40196009; PMCID: PMC11975022.
Comstock WJ, Navarro MV, Maybee DV, Rho Y, Wagner M, Wang Y, Smolka MB. Proteomic Sensors for Quantitative, Multiplexed and Spatial Monitoring of Kinase Signaling. bioRxiv [Preprint]. 2025 Mar 13:2024.12.16.628391. doi: 10.1101/2024.12.16.628391. PMID: 39764013; PMCID: PMC11702526.
Comstock WJ, Bhattarai S, Sanford EJ, Navarro MVAS, Smolka MB. Profiling Tel1 signaling reveals a non-canonical motif targeting DNA repair and telomere control machineries. J Biol Chem. 2025 Mar;301(3):108194. doi: 10.1016/j.jbc.2025.108194. Epub 2025 Jan 16. PMID: 39826692; PMCID: PMC11875207.
Hall PM, Mayse LA, Bai L, Smolka MB, Pugh BF, Wang MD. High-Resolution Genome-Wide Maps Reveal Widespread Presence of Torsional Insulation. bioRxiv [Preprint]. 2025 Jan 4:2024.10.11.617876. doi: 10.1101/2024.10.11.617876. PMID: 39416127; PMCID: PMC11482950.

2024

Du H, Yang C, Nana AL, Seeley WW, Smolka M, Hu F. WITHDRAWN: Progranulin inhibits phospholipase sPLA2-IIA to control neuroinflammation. bioRxiv [Preprint]. 2024 Dec 13:2023.04.06.535844. doi: 10.1101/2023.04.06.535844. Update in: Mol Neurodegener. 2025 Jun 17;20(1):72. doi: 10.1186/s13024-025-00863-8. PMID: 37066328; PMCID: PMC10104136.
Wan M, Minelli ME, Zhao Q, Marshall S, Yu H, Smolka M, Mao Y. Phosphoribosyl modification of poly-ubiquitin chains at the Legionella-containing vacuole prohibiting autophagy adaptor recognition. Nat Commun. 2024 Aug 30;15(1):7481. doi: 10.1038/s41467-024-51273-1. PMID: 39214972; PMCID: PMC11364841.
Cao X, Huang S, Wagner MM, Cho YT, Chiu DC, Wartchow KM, Lazarian A, McIntire LB, Smolka MB, Baskin JM. A phosphorylation-controlled switch confers cell cycle-dependent protein relocalization. Nat Cell Biol. 2024 Oct;26(10):1804-1816. doi: 10.1038/s41556-024-01495-8. Epub 2024 Aug 29. PMID: 39209962; PMCID: PMC11559143.
Marshall S, Navarro MVAS, Ascenҫão CFR, Dibitetto D, Smolka MB. In-depth mapping of DNA-PKcs signaling uncovers noncanonical features of its kinase specificity. J Biol Chem. 2024 Aug;300(8):107513. doi: 10.1016/j.jbc.2024.107513. Epub 2024 Jun 28. PMID: 38945450; PMCID: PMC11327452.
Xie B, Sanford EJ, Hung SH, Wagner M, Heyer WD, Smolka MB. Multi-step control of homologous recombination via Mec1/ATR suppresses chromosomal rearrangements. EMBO J. 2024 Jul;43(14):3027-3043. doi: 10.1038/s44318-024-00139-9. Epub 2024 Jun 5. PMID: 38839993; PMCID: PMC11251156.
Ascenção C, Sims JR, Dziubek A, Comstock W, Fogarty EA, Badar J, Freire R, Grimson A, Weiss RS, Cohen PE, Smolka MB. A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation. Elife. 2024 Feb 23;12:RP90887. doi: 10.7554/eLife.90887. PMID: 38391183; PMCID: PMC10942628.
Horan TS, Ascenção CFR, Mellor C, Wang M, Smolka MB, Cohen PE. The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice. PLoS Genet. 2024 Feb 20;20(2):e1011175. doi: 10.1371/journal.pgen.1011175. PMID: 38377115; PMCID: PMC10906868.

2023

Ferreira GA, Thomé CH, Izumi C, Grassi ML, Lanfredi GP, Smolka M, Faça VM, Candido Dos Reis FJ. Proteomic analysis of exosomes secreted during the epithelial-mesenchymal transition and potential biomarkers of mesenchymal high-grade serous ovarian carcinoma. J Ovarian Res. 2023 Nov 29;16(1):232. doi: 10.1186/s13048-023-01304-0. PMID: 38031074; PMCID: PMC10685605.
Smolka MB, Lammerding J. ATR takes a crack at the nuclear envelope. Mol Cell. 2023 Oct 19;83(20):3588-3590. doi: 10.1016/j.molcel.2023.09.031. PMID: 37863026.
Ho B, Sanford EJ, Loll-Krippleber R, Torres NP, Smolka MB, Brown GW. Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics. Elife. 2023 Jun 6;12:e82483. doi: 10.7554/eLife.82483. PMID: 37278514; PMCID: PMC10259420.

2022

Dibitetto D, Marshall S, Sanchi A, Liptay M, Badar J, Lopes M, Rottenberg S, Smolka MB. DNA-PKcs promotes fork reversal and chemoresistance. Mol Cell. 2022 Oct 20;82(20):3932-3942.e6. doi: 10.1016/j.molcel.2022.08.028. Epub 2022 Sep 20. PMID: 36130596; PMCID: PMC9588680.
Cao X, Shami Shah A, Sanford EJ, Smolka MB, Baskin JM. Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor. ACS Chem Biol. 2022 Sep 16;17(9):2605-2618. doi: 10.1021/acschembio.2c00527. Epub 2022 Aug 11. PMID: 35952650; PMCID: PMC9933862.
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, Lammerding J. Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer. Oncogene. 2022 Sep;41(36):4211-4230. doi: 10.1038/s41388-022-02420-9. Epub 2022 Jul 27. PMID: 35896617; PMCID: PMC9925375.
Caballero M, Ge T, Rebelo AR, Seo S, Kim S, Brooks K, Zuccaro M, Kanagaraj R, Vershkov D, Kim D, Smogorzewska A, Smolka M, Benvenisty N, West SC, Egli D, Mace EM, Koren A. Comprehensive analysis of DNA replication timing across 184 cell lines suggests a role for MCM10 in replication timing regulation. Hum Mol Genet. 2022 Aug 25;31(17):2899-2917. doi: 10.1093/hmg/ddac082. PMID: 35394024; PMCID: PMC9433724.
Sanford EJ, Smolka MB. A field guide to the proteomics of post-translational modifications in DNA repair. Proteomics. 2022 Aug;22(15-16):e2200064. doi: 10.1002/pmic.202200064. Epub 2022 Jun 26. PMID: 35695711; PMCID: PMC9950963.
Sims JR, Faça VM, Pereira C, Ascenção C, Comstock W, Badar J, Arroyo-Martinez GA, Freire R, Cohen PE, Weiss RS, Smolka MB. Phosphoproteomics of ATR signaling in mouse testes. Elife. 2022 Feb 8;11:e68648. doi: 10.7554/eLife.68648. PMID: 35133275; PMCID: PMC8824463.
Pereira C, Arroyo-Martinez GA, Guo MZ, Downey MS, Kelly ER, Grive KJ, Mahadevaiah SK, Sims JR, Faca VM, Tsai C, Schiltz CJ, Wit N, Jacobs H, Clark NL, Freire R, Turner J, Lyndaker AM, Brieno-Enriquez MA, Cohen PE, Smolka MB, Weiss RS. Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis. Elife. 2022 Feb 8;11:e68677. doi: 10.7554/eLife.68677. PMID: 35133274; PMCID: PMC8824475.

2021

Sanford EJ, Smolka MB. Fe-NTA Microcolumn Purification of Phosphopeptides from Immunoprecipitation (IP) Eluates for Mass Spectrometry Analysis. Bio Protoc. 2021 Aug 5;11(15):e4113. doi: 10.21769/BioProtoc.4113. PMID: 34458407; PMCID: PMC8376508.
Pellicanò G, Al Mamun M, Jurado-Santiago D, Villa-Hernández S, Yin X, Giannattasio M, Lanz MC, Smolka MB, Yeeles J, Shirahige K, García-Díaz M, Bermejo R. Checkpoint-mediated DNA polymerase ε exonuclease activity curbing counteracts resection-driven fork collapse. Mol Cell. 2021 Jul 1;81(13):2778-2792.e4. doi: 10.1016/j.molcel.2021.04.006. Epub 2021 Apr 30. PMID: 33932350; PMCID: PMC7612761.
Joiner AM, Phillips BP, Yugandhar K, Sanford EJ, Smolka MB, Yu H, Miller EA, Fromme JC. Structural basis of TRAPPIII-mediated Rab1 activation. EMBO J. 2021 Jun 15;40(12):e107607. doi: 10.15252/embj.2020107607. Epub 2021 May 21. PMID: 34018207; PMCID: PMC8204860.
Sanford EJ, Comstock WJ, Faça VM, Vega SC, Gnügge R, Symington LS, Smolka MB. Phosphoproteomics reveals a distinctive Mec1/ATR signaling response upon DNA end hyper-resection. EMBO J. 2021 May 17;40(10):e104566. doi: 10.15252/embj.2020104566. Epub 2021 Mar 25. PMID: 33764556; PMCID: PMC8126923.
Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB. In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep. 2021 Feb 3;22(2):e51121. doi: 10.15252/embr.202051121. Epub 2021 Jan 25. PMID: 33491328; PMCID: PMC7857435.

Stuhlmann

2024

Shahriar S, Biswas S, Zhao K, Akcan U, Tuohy MC, Glendinning MD, Kurt A, Wayne CR, Prochilo G, Price MZ, Stuhlmann H, Brekken RA, Menon V, Agalliu D. VEGF-A-mediated venous endothelial cell proliferation results in neoangiogenesis during neuroinflammation. Nat Neurosci. 2024 Oct;27(10):1904-1917. doi: 10.1038/s41593-024-01746-9. Epub 2024 Sep 10. PMID: 39256571.
Salvi S, Fruci S, Lacconi V, Totaro Aprile F, Rullo R, Stuhlmann H, Lanzone A, Campagnolo L, Massimiani M. Effect of Pravastatin on Placental Expression of Epidermal Growth Factor-like Domain 7 in Early-Onset Pre-Eclampsia: A New Potential Mechanism of Action. Biomedicines. 2024 Aug 22;12(8):1929. doi: 10.3390/biomedicines12081929. PMID: 39200393; PMCID: PMC11351877.
Chen RJ, Nabila A, Gal Toth J, Stuhlmann H, Toth M. The chemokine XCL1 functions as a pregnancy hormone to program offspring innate anxiety. Brain Behav Immun. 2024 May;118:178-189. doi: 10.1016/j.bbi.2024.02.032. Epub 2024 Feb 29. PMID: 38428650; PMCID: PMC11044916.

2023

Jin JC, Ananthanarayanan A, Brown JA, Rager SL, Bram Y, Sanidad KZ, Amir M, Baergen RN, Stuhlmann H, Schwartz RE, Perlman JM, Zeng MY. SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy. Pediatr Res. 2023 Apr;93(5):1375-1382. doi: 10.1038/s41390-022-02266-7. Epub 2022 Aug 19. PMID: 35986143; PMCID: PMC9388973.

2022

Chen RJ, Nabila A, Phalke S, Castro DF, Toth JG, Bergin P, Bastiaans J, Stuhlmann H, Pernis AB, Toth M. Serotonin-1A receptor, a psychiatric disease risk factor, influences offspring immunity via sex-dependent genetic nurture. iScience. 2022 Nov 15;25(12):105595. doi: 10.1016/j.isci.2022.105595. PMID: 36458257; PMCID: PMC9706704.
Argueta LB, Lacko LA, Bram Y, Tada T, Carrau L, Rendeiro AF, Zhang T, Uhl S, Lubor BC, Chandar V, Gil C, Zhang W, Dodson BJ, Bastiaans J, Prabhu M, Houghton S, Redmond D, Salvatore CM, Yang YJ, Elemento O, Baergen RN, tenOever BR, Landau NR, Chen S, Schwartz RE, Stuhlmann H. Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy. iScience. 2022 May 20;25(5):104223. doi: 10.1016/j.isci.2022.104223. Epub 2022 Apr 11. PMID: 35434541; PMCID: PMC8996470.

2021

Massimiani M, Salvi S, Tiralongo GM, Moresi S, Stuhlmann H, Valensise H, Lanzone A, Campagnolo L. Circulating EGFL7 distinguishes between IUGR and PE: an observational case-control study. Sci Rep. 2021 Sep 9;11(1):17919. doi: 10.1038/s41598-021-97482-2. PMID: 34504270; PMCID: PMC8429426.
Coelho-Santos V, Berthiaume AA, Ornelas S, Stuhlmann H, Shih AY. Imaging the construction of capillary networks in the neonatal mouse brain. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2100866118. doi: 10.1073/pnas.2100866118. PMID: 34172585; PMCID: PMC8256089.
Massimiani M, Tiralongo GM, Salvi S, Fruci S, Lacconi V, La Civita F, Mancini M, Stuhlmann H, Valensise H, Campagnolo L. Treatment of pregnancies complicated by intrauterine growth restriction with nitric oxide donors increases placental expression of Epidermal Growth Factor-Like Domain 7 and improves fetal growth: A pilot study. Transl Res. 2021 Feb;228:28-41. doi: 10.1016/j.trsl.2020.08.002. Epub 2020 Aug 9. PMID: 32784003.

Travis

2025

Dallal Bashi YH, Zhao X, McCoy CF, Kumar N, Teleshova N, Lamb DJ, Fernández Romero JA, Meyer A, Barnable P, Aravantinou M, Asowata OE, White MA, Travis AJ, Haddad LB, Shen X, Young VL, Boyd P, Malcolm RK. A prodrug strategy for sustained release of lactic acid from silicone elastomer vaginal rings. Int J Pharm. 2025 Nov 10;684:126120. doi: 10.1016/j.ijpharm.2025.126120. Epub 2025 Aug 26. PMID: 40876768.
Sosnicki DM, Travis AJ, Comizzoli P. In vitro exposure to epididymal extracellular vesicles from normospermic domestic cats improves developmental potential of sperm from teratospermic cats. Front Vet Sci. 2025 Jan 17;12:1547175. doi: 10.3389/fvets.2025.1547175. PMID: 39896847; PMCID: PMC11783848.
White MA, Cohen R, Travis AJ. Real-Time Imaging of Calcium Dynamics in Human Sperm After Precise Single-Cell Stimulation. Methods Mol Biol. 2025;2861:247-256. doi: 10.1007/978-1-0716-4164-4_18. PMID: 39395110.

2024

Sosnicki DM, Travis AJ, Comizzoli P. Extracellular vesicles are involved in the paracrine communication between epithelial cells in different regions of the domestic cat epididymis†. Biol Reprod. 2024 Nov 11;111(5):1056-1070. doi: 10.1093/biolre/ioae129. PMID: 39190878.
Meredith GR, Leong D, Frost C, Travis AJ. Facilitated Asynchronous Online Learning to Build Public Health Strategic Skills. J Public Health Manag Pract. 2024 Jan-Feb 01;30(1):56-65. doi: 10.1097/PHH.0000000000001813. Epub 2023 Aug 29. PMID: 37643075; PMCID: PMC10664790.

2023

Sosnicki DM, Cohen R, Asano A, Nelson JL, Mukai C, Comizzoli P, Travis AJ. Segmental differentiation of the murine epididymis: identification of segment-specific, GM1-enriched vesicles and regulation by luminal fluid factors†. Biol Reprod. 2023 Dec 11;109(6):864-877. doi: 10.1093/biolre/ioad120. PMID: 37694824; PMCID: PMC10724454.
Cohen R, Sosnicki DM, White MA, Nelson JL, Mukai C, Travis AJ. Real-Time Imaging of Acrosomal Calcium Dynamics and Exocytosis in Live Mouse Sperm. J Vis Exp. 2023 Oct 13;(200). doi: 10.3791/65962. PMID: 37902325.
Sharara FI, Ostermeier GC, Travis AJ. Defects in sperm capacitation/fertilizing ability are equally prevalent across ages in men seeking fertility assistance. Reprod Biomed Online. 2023 Jan;46(1):179-187. doi: 10.1016/j.rbmo.2022.09.020. Epub 2022 Sep 26. PMID: 36371338.

2022

Cummings KJ, Clarkberg M, Busche J, Travis AJ, Meredith GR, Weisfuse I, Cazer CL, Koretzky GA, Warnick LD. Case-control study to identify risk factors for SARS-CoV-2 infection among university students in the northeastern USA. Transbound Emerg Dis. 2022 Sep;69(5):e2688-e2693. doi: 10.1111/tbed.14619. Epub 2022 Jun 29. PMID: 35687478; PMCID: PMC9348057.
Meredith GR, Osman M, Cazer CL, Cummings KJ, Hecht J, Madsen CG, Santacrose LB, Dubovi AS, Clarkberg M, Johnson T, Fitzpatrick MD, Parrilla L, Li Y, Francis L, Weisfuse IB, Travis AJ, Jones AC, Warnick LD, Koretzky GA. Integrated Surveillance System for Controlling COVID-19 on a University Campus, 2020‒2021. Am J Public Health. 2022 Jul;112(7):980-984. doi: 10.2105/AJPH.2022.306838. PMID: 35728024; PMCID: PMC9222446.
Cohen R, Mukai C, Nelson JL, Zenilman SS, Sosnicki DM, Travis AJ. A genetically targeted sensor reveals spatial and temporal dynamics of acrosomal calcium and sperm acrosome exocytosis. J Biol Chem. 2022 May;298(5):101868. doi: 10.1016/j.jbc.2022.101868. Epub 2022 Mar 27. PMID: 35346690; PMCID: PMC9046242.

Van der Meulen

2025

McNeill TJ, Rooney AM, Ross FP, Bostrom MPG, van der Meulen MCH. PTH pre-treatment prior to tibial mechanical loading improves their synergistic anabolic effects in mice. Bone. 2025 Jul;196:117474. doi: 10.1016/j.bone.2025.117474. Epub 2025 Mar 29. PMID: 40164271.
Chlebek C, Raynor MS, Ross FP, van der Meulen MCH. The skeletal transcriptional response to mechanical load varies with age and tissue compartment in female mice. JBMR Plus. 2025 Jun 14;9(9):ziaf105. doi: 10.1093/jbmrpl/ziaf105. PMID: 40800665; PMCID: PMC12342466.
Chlebek C, McNeill TJ, Huang M, Raynor MS, van der Meulen MCH. Bioenergetic programs of cancellous and cortical bone are distinct and differ with age and mechanical loading. Sci Rep. 2025 May 31;15(1):19134. doi: 10.1038/s41598-025-02141-5. PMID: 40450018; PMCID: PMC12126591.

2024

Antoinette AY, Ziemian SN, Brown AR, Hudson EB, Chlebek C, Wright TM, Goldring SR, Goldring MB, Otero M, van der Meulen MCH. PTH treatment before cyclic joint loading improves cartilage health and attenuates load-induced osteoarthritis development in mice. Sci Adv. 2024 Apr 19;10(16):eadk8402. doi: 10.1126/sciadv.adk8402. Epub 2024 Apr 19. PMID: 38640238; PMCID: PMC11029811.
Wheeler TA, Antoinette AY, Bhatia E, Kim MJ, Ijomanta CN, Zhao A, van der Meulen MCH, Singh A. Mechanical loading of joint modulates T cells in lymph nodes to regulate osteoarthritis. Osteoarthritis Cartilage. 2024 Mar;32(3):287-298. doi: 10.1016/j.joca.2023.11.021. Epub 2023 Dec 10. PMID: 38072172; PMCID: PMC10955501.
Subramaniam S, Akay M, Anastasio MA, Bailey V, Boas D, Bonato P, Chilkoti A, Cochran JR, Colvin V, Desai TA, Duncan JS, Epstein FH, Fraley S, Giachelli C, Grande-Allen KJ, Green J, Guo XE, Hilton IB, Humphrey JD, Johnson CR, Karniadakis G, King MR, Kirsch RF, Kumar S, Laurencin CT, Li S, Lieber RL, Lovell N, Mali P, Margulies SS, Meaney DF, Ogle B, Palsson B, A Peppas N, Perreault EJ, Rabbitt R, Setton LA, Shea LD, Shroff SG, Shung K, Tolias AS, van der Meulen MCH, Varghese S, Vunjak-Novakovic G, White JA, Winslow R, Zhang J, Zhang K, Zukoski C, Miller MI. Grand Challenges at the Interface of Engineering and Medicine. IEEE Open J Eng Med Biol. 2024 Feb 21;5:1-13. doi: 10.1109/OJEMB.2024.3351717. PMID: 38415197; PMCID: PMC10896418.

2023

Christiansen BA, Chan DD, van der Meulen MCH, Maerz T. Small-Animal Compression Models of Osteoarthritis. Methods Mol Biol. 2023;2598:345-356. doi: 10.1007/978-1-0716-2839-3_25. PMID: 36355304; PMCID: PMC10521326.
Damle SR, Krzyzanowska AK, Korsun MK, Morse KW, Gilbert S, Kim HJ, Boachie-Adjei O, Rawlins BA, van der Meulen MCH, Greenblatt MB, Hidaka C, Cunningham ME. Inducing Angiogenesis in the Nucleus Pulposus. Cells. 2023 Oct 19;12(20):2488. doi: 10.3390/cells12202488. PMID: 37887332; PMCID: PMC10605635.
Haller JM, van der Meulen MCH, Olson S, Anderson D, Marsh JL, Working Z. Posttraumatic osteoarthritis: from basic science to clinical implications. OTA Int. 2023 May 4;6(2 Suppl):e232. doi: 10.1097/OI9.0000000000000232. PMID: 37168031; PMCID: PMC10166366.
Rooney AM, McNeill TJ, Ross FP, Bostrom MPG, van der Meulen MCH. PTH Treatment Increases Cortical Bone Mass More in Response to Compression than Tension in Mice. J Bone Miner Res. 2023 Jan;38(1):59-69. doi: 10.1002/jbmr.4728. Epub 2022 Nov 12. PMID: 36281491; PMCID: PMC12054691.

2022

Chlebek C, Moore JA, Ross FP, van der Meulen MCH. Molecular Identification of Spatially Distinct Anabolic Responses to Mechanical Loading in Murine Cortical Bone. J Bone Miner Res. 2022 Nov;37(11):2277-2287. doi: 10.1002/jbmr.4686. Epub 2022 Sep 17. PMID: 36054133.
Cunningham ME, Kelly NH, Rawlins BA, Boachie-Adjei O, van der Meulen MCH, Hidaka C. Lumbar spine intervertebral disc gene delivery of BMPs induces anterior spine fusion in lewis rats. Sci Rep. 2022 Oct 7;12(1):16847. doi: 10.1038/s41598-022-21208-1. PMID: 36207369; PMCID: PMC9547004.
Kim JM, Yang YS, Hong J, Chaugule S, Chun H, van der Meulen MCH, Xu R, Greenblatt MB, Shim JH. Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway. Elife. 2022 Aug 17;11:e78069. doi: 10.7554/eLife.78069. PMID: 35975983; PMCID: PMC9417416.
Ayobami OO, Goldring SR, Goldring MB, Wright TM, van der Meulen MCH. Contribution of joint tissue properties to load-induced osteoarthritis. Bone Rep. 2022 Jul 19;17:101602. doi: 10.1016/j.bonr.2022.101602. PMID: 35899096; PMCID: PMC9309407.
Rooney AM, Ayobami OO, Kelly NH, Schimenti JC, Ross FP, van der Meulen MCH. Bone mass and adaptation to mechanical loading are sexually dimorphic in adult osteoblast-specific ERα knockout mice. Bone. 2022 May;158:116349. doi: 10.1016/j.bone.2022.116349. Epub 2022 Feb 3. PMID: 35123146; PMCID: PMC12331412.
Glorieux FH, Bonewald LF, Harvey NC, van der Meulen MCH. Potential influences on optimizing long-term musculoskeletal health in children and adolescents with X-linked hypophosphatemia (XLH). Orphanet J Rare Dis. 2022 Jan 31;17(1):30. doi: 10.1186/s13023-021-02156-x. PMID: 35101067; PMCID: PMC8802511.

2021

Ziemian SN, Ayobami OO, Rooney AM, Kelly NH, Holyoak DT, Ross FP, van der Meulen MCH. Low bone mass resulting from impaired estrogen signaling in bone increases severity of load-induced osteoarthritis in female mice. Bone. 2021 Nov;152:116071. doi: 10.1016/j.bone.2021.116071. Epub 2021 Jun 24. PMID: 34171515; PMCID: PMC8863567.
Ziemian SN, Witkowski AM, Wright TM, Otero M, van der Meulen MCH. Early inhibition of subchondral bone remodeling slows load-induced posttraumatic osteoarthritis development in mice. J Bone Miner Res. 2021 Oct;36(10):2027-2038. doi: 10.1002/jbmr.4397. Epub 2021 Jul 16. PMID: 34155675; PMCID: PMC8815449.
Choi JH, Wang Z, Ross FP, van der Meulen MCH, Bostrom MPG. Systemic osteoprotegerin does not improve peri-implant bone volume or osseointegration in rabbits. J Orthop Res. 2021 Aug;39(8):1611-1621. doi: 10.1002/jor.24884. Epub 2020 Oct 27. PMID: 33049072.
Dvorzhinskiy A, Perino G, Chojnowski R, van der Meulen MCH, Bostrom MPG, Yang X. Ceramic composite with gentamicin decreases persistent infection and increases bone formation in a rat model of debrided osteomyelitis. J Bone Jt Infect. 2021 Jul 20;6(7):283-293. doi: 10.5194/jbji-6-283-2021. PMID: 34345576; PMCID: PMC8320378.
Luna M, Guss JD, Vasquez-Bolanos LS, Alepuz AJ, Dornevil S, Strong J, Alabi D, Shi Q, Pannellini T, Otero M, Brito IL, van der Meulen MCH, Goldring SR, Hernandez CJ. Obesity and load-induced posttraumatic osteoarthritis in the absence of fracture or surgical trauma. J Orthop Res. 2021 May;39(5):1007-1016. doi: 10.1002/jor.24799. Epub 2020 Jul 17. PMID: 32658313; PMCID: PMC7855296.

Vitousek

2025

Taff CC, Wingfield JC, Vitousek MN. Corticosterone Reaction Norms to Temperature in Wild Birds: Implications for Understanding Endocrine Flexibility and Climate Vulnerability. Integr Comp Biol. 2025 Oct 16;65(4):1051-1060. doi: 10.1093/icb/icaf011. PMID: 40199741.
Real MVF, Vitousek MN, Sheehan MJ, Moeller AH. The mouse gut microbiota responds to predator odor and predicts host behavior. bioRxiv [Preprint]. 2025 Sep 25:2025.07.01.662568. doi: 10.1101/2025.07.01.662568. PMID: 40631147; PMCID: PMC12236647.
Vitousek MN, Taff CC, Williamson JL. Resilience and robustness: from sub-organismal responses to communities. Trends Ecol Evol. 2025 May;40(5):468-478. doi: 10.1016/j.tree.2025.03.001. Epub 2025 Mar 27. PMID: 40148158.
Wolf SE, Woodruff MJ, Chang van Oordt DA, Clotfelter ED, Cristol DA, Derryberry EP, Ferguson SM, Stanback MT, Taff CC, Vitousek MN, Westneat DF, Rosvall KA. Among-population variation in telomere regulatory proteins and their potential role as hidden drivers of intraspecific variation in life history. J Anim Ecol. 2025 Mar;94(3):303-315. doi: 10.1111/1365-2656.14071. Epub 2024 Mar 21. PMID: 38509838; PMCID: PMC11415550.
Rohwer VG, Houtz JL, Vitousek MN, Bailey RL, Miller ET. The Evolution of Using Shed Snake Skin in Bird Nests. Am Nat. 2025 Feb;205(2):170-183. doi: 10.1086/733208. Epub 2024 Dec 18. PMID: 39913940.

2024

Uehling JJ, Regnier E, Vitousek MN. Does Migration Constrain Glucocorticoid Phenotypes? Testing Corticosterone Levels during Breeding in Migratory Versus Resident Birds. Integr Comp Biol. 2024 Dec 20;64(6):1826-1835. doi: 10.1093/icb/icae110. PMID: 38992259.
McNew SM, Taff CC, Vitousek MN. Manipulation of a social signal affects DNA methylation of a stress-related gene in a free-living bird. J Exp Biol. 2024 Aug 1;227(15):jeb246819. doi: 10.1242/jeb.246819. Epub 2024 Jul 30. PMID: 39022893; PMCID: PMC11418189.
Schoenle LA, Zimmer C, Miller ET, Vitousek MN. Corrigendum to “Does variation in glucocorticoid concentrations predict fitness? A phylogenetic meta-analysis” [Gen. Comp. Endocrinol. 300 (2021) 113611]. Gen Comp Endocrinol. 2024 Aug 1;354:114518. doi: 10.1016/j.ygcen.2024.114518. Epub 2024 Apr 26. Erratum for: Gen Comp Endocrinol. 2021 Jan 1;300:113611. doi: 10.1016/j.ygcen.2020.113611. PMID: 38670848.
Taff CC, McNew SM, Campagna L, Vitousek MN. Corticosterone exposure is associated with long-term changes in DNA methylation, physiology and breeding decisions in a wild bird. Mol Ecol. 2024 Aug;33(15):e17456. doi: 10.1111/mec.17456. Epub 2024 Jul 2. PMID: 38953311.
Uehling JJ, Regnier E, Vitousek MN. Does migration constrain glucocorticoid phenotypes? Testing corticosterone levels during breeding in migratory versus resident birds. Integr Comp Biol. 2024 Jul 11:icae110. doi: 10.1093/icb/icae110. Epub ahead of print. PMID: 38992259.
McNew SM, Taff CC, Zimmer C, Uehling JJ, Ryan TA, Chang van Oordt D, Houtz JL, Injaian AS, Vitousek MN. Developmental stage-dependent effects of perceived predation risk on nestling tree swallows (Tachycineta bicolor). Ecology. 2024 Jun;105(6):e4307. doi: 10.1002/ecy.4307. Epub 2024 May 9. PMID: 38724013.
Chang van Oordt DA, Taff CC, Pipkin MA, Ryan TA, Vitousek MN. Experimentally elevated corticosterone does not affect bacteria killing ability of breeding female tree swallows (Tachycineta bicolor). Horm Behav. 2024 Apr;160:105500. doi: 10.1016/j.yhbeh.2024.105500. Epub 2024 Feb 4. PMID: 38316079.
Taff CC, Baldan D, Mentesana L, Ouyang JQ, Vitousek MN, Hau M. Endocrine flexibility can facilitate or constrain the ability to cope with global change. Philos Trans R Soc Lond B Biol Sci. 2024 Mar 25;379(1898):20220502. doi: 10.1098/rstb.2022.0502. Epub 2024 Feb 5. PMID: 38310929; PMCID: PMC10838644.
Wolf SE, Woodruff MJ, Chang van Oordt DA, Clotfelter ED, Cristol DA, Derryberry EP, Ferguson SM, Stanback MT, Taff CC, Vitousek MN, Westneat DF, Rosvall KA. Among-population variation in telomere regulatory proteins and their potential role as hidden drivers of intraspecific variation in life history. J Anim Ecol. 2024 Mar 21:10.1111/1365-2656.14071. doi: 10.1111/1365-2656.14071. Epub ahead of print. PMID: 38509838; PMCID: PMC11415550.

2023

Taff CC, McNew SM, Zimmer C, Uehling JJ, Houtz JL, Ryan TA, Chang van Oordt D, Injaian AS, Vitousek MN. Social signal manipulation and environmental challenges have independent effects on physiology, internal microbiome, and reproductive performance in tree swallows (Tachycineta bicolor). J Exp Zool A Ecol Integr Physiol. 2023 Oct;339(8):723-735. doi: 10.1002/jez.2722. Epub 2023 Jun 12. PMID: 37306329.
Vitousek MN, Dantzer B, Fuxjager MJ, Schlinger BA. Evolutionary behavioral endocrinology: Introduction to the special issue. Horm Behav. 2023 Jun;152:105356. doi: 10.1016/j.yhbeh.2023.105356. Epub 2023 Apr 7. PMID: 37031556.
Ryan TA, Taff CC, Zimmer C, Vitousek MN. Cold temperatures induce priming of the glucose stress response in tree swallows. Comp Biochem Physiol A Mol Integr Physiol. 2023 Jun;280:111419. doi: 10.1016/j.cbpa.2023.111419. Epub 2023 Mar 23. PMID: 36965830.
Zimmer C, Taff CC, Ardia DR, Rosvall KA, Kallenberg C, Bentz AB, Taylor AR, Johnson LS, Vitousek MN. Gene expression in the female tree swallow brain is associated with inter- and intra-population variation in glucocorticoid levels. Horm Behav. 2023 Jan;147:105280. doi: 10.1016/j.yhbeh.2022.105280. Epub 2022 Nov 17. PMID: 36403365.

2022

Chang van Oordt DA, Taff CC, Ryan TA, Vitousek MN. Timing of Breeding Reveals a Trade-Off between Immune Investment and Life History in Tree Swallows. Integr Comp Biol. 2022 Dec 30;62(6):1629-1639. doi: 10.1093/icb/icac033. PMID: 35561702.
Houtz JL, Taff CC, Vitousek MN. Gut Microbiome as a Mediator of Stress Resilience: A Reactive Scope Model Framework. Integr Comp Biol. 2022 Aug 13;62(1):41-57. doi: 10.1093/icb/icac030. PMID: 35544275.
Taff CC, Wingfield JC, Vitousek MN. The relative speed of the glucocorticoid stress response varies independently of scope and is predicted by environmental variability and longevity across birds. Horm Behav. 2022 Aug;144:105226. doi: 10.1016/j.yhbeh.2022.105226. Epub 2022 Jul 18. PMID: 35863083.
Miller CR, Vitousek MN, Thaler JS. Light at night disrupts trophic interactions and population growth of lady beetles and pea aphids. Oecologia. 2022 Jul;199(3):527-535. doi: 10.1007/s00442-022-05146-3. Epub 2022 Mar 17. PMID: 35298703.
Taff CC, Zimmer C, Ryan TA, van Oordt DC, Aborn DA, Ardia DR, Johnson LS, Rose AP, Vitousek MN. Individual variation in natural or manipulated corticosterone does not covary with circulating glucose in a wild bird. J Exp Biol. 2022 Feb 15;225(4):jeb243262. doi: 10.1242/jeb.243262. Epub 2022 Feb 24. PMID: 35072205.

2021

Injaian AS, Uehling JJ, Taff CC, Vitousek MN. Effects of Artificial Light at Night on Avian Provisioning, Corticosterone, and Reproductive Success. Integr Comp Biol. 2021 Oct 4;61(3):1147-1159. doi: 10.1093/icb/icab055. PMID: 34021748.
Husak JF, Fuxjager MJ, Johnson MA, Vitousek MN, Donald JW, Francis CD, Goymann W, Hau M, Kircher BK, Knapp R, Martin LB, Miller ET, Schoenle LA, Williams TD. Life history and environment predict variation in testosterone across vertebrates. Evolution. 2021 May;75(5):1003-1010. doi: 10.1111/evo.14216. Epub 2021 Apr 2. PMID: 33755201.
Schoenle LA, Zimmer C, Miller ET, Vitousek MN. Does variation in glucocorticoid concentrations predict fitness? A phylogenetic meta-analysis. Gen Comp Endocrinol. 2021 Jan 1;300:113611. doi: 10.1016/j.ygcen.2020.113611. Epub 2020 Sep 18. Erratum in: Gen Comp Endocrinol. 2024 Aug 1;354:114518. doi: 10.1016/j.ygcen.2024.114518. PMID: 32950580.

Weiss

2025

Tavares NT, Lourenço C, Constâncio V, Fernandes-Pontes F, Fonseca D, Silva-Santos R, Braga I, Maurício J, Henrique R, Liu M, Weiss RS, Bagrodia A, Jerónimo C, Lobo J. MicroRNA-371-373 cluster extracellular vesicle-based communication in testicular germ cell tumors. Cell Commun Signal. 2025 May 30;23(1):252. doi: 10.1186/s12964-025-02250-8. PMID: 40448114; PMCID: PMC12124061.
Loehr AR, Timmerman DM, Liu M, Gillis AJM, Matthews M, Bloom JC, Nicholls PK, Page DC, Miller AD, Looijenga LHJ, Weiss RS. Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection. Sci Rep. 2025 Feb 6;15(1):4452. doi: 10.1038/s41598-025-88554-8. PMID: 39910147; PMCID: PMC11799207.

2024

Zhang B, Mullmann J, Ludewig AH, Fernandez IR, Bales TR, Weiss RS, Schroeder FC. Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites. Nat Chem Biol. 2024 Jul;20(7):812-822. doi: 10.1038/s41589-023-01511-2. Epub 2024 Jan 2. PMID: 38167917.
Ascenção C, Sims JR, Dziubek A, Comstock W, Fogarty EA, Badar J, Freire R, Grimson A, Weiss RS, Cohen PE, Smolka MB. A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation. Elife. 2024 Feb 23;12:RP90887. doi: 10.7554/eLife.90887. PMID: 38391183; PMCID: PMC10942628.
Erstling JA, Bag N, Gardinier TC, Kohle FFE, DomNwachukwu N, Butler SD, Kao T, Ma K, Turker MZ, Feuer GB, Lee R, Naguib N, Tallman JF, Malarkey HF, Tsaur L, Moore WL, Chapman DV, Aubert T, Mehta S, Cerione RA, Weiss RS, Baird BA, Wiesner UB. Overcoming Barriers Associated with Oral Delivery of Differently Sized Fluorescent Core-Shell Silica Nanoparticles. Adv Mater. 2024 Jan;36(1):e2305937. doi: 10.1002/adma.202305937. Epub 2023 Nov 23. PMID: 37689973.

2023

Shioda T, Weiss RS, Bagrodia A, Frazier AL. Comment on “Comment on ‘A Nested Case-Control Study of Serum Per- and Polyfluoroalkyl Substances and Testicular Germ Cell Tumors among U.S. Air Force Servicemen'”. Environ Health Perspect. 2023 Dec;131(12):128001. doi: 10.1289/EHP14247. Epub 2023 Dec 15. PMID: 38099920; PMCID: PMC10723136.
Roberts LC, Warnick LD, Weiss RS. Genomics at Cornell University College of Veterinary Medicine. Am J Vet Res. 2023 Jul 18;84(8):ajvr.23.06.0127. doi: 10.2460/ajvr.23.06.0127. PMID: 37442545.

2022

Latifkar A, Wang F, Mullmann JJ, Panizza E, Fernandez IR, Ling L, Miller AD, Fischbach C, Weiss RS, Lin H, Cerione RA, Antonyak MA. IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2200477119. doi: 10.1073/pnas.2200477119. Epub 2022 Nov 2. PMID: 36322753; PMCID: PMC9659396.
Fonseca A, Lobo J, Hazard FK, Gell J, Nicholls PK, Weiss RS, Klosterkemper L, Volchenboum SL, Nicholson JC, Frazier AL, Amatruda JF, Bagrodia A, Lockley M, Murray MJ. Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium. Br J Cancer. 2022 Nov;127(9):1577-1583. doi: 10.1038/s41416-022-02000-4. Epub 2022 Oct 13. PMID: 36229581; PMCID: PMC9596690.
Shah P, McGuigan CW, Cheng S, Vanpouille-Box C, Demaria S, Weiss RS, Lammerding J. ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels. Front Cell Dev Biol. 2022 Jun 1;10:875132. doi: 10.3389/fcell.2022.875132. PMID: 35721517; PMCID: PMC9198445.
Zhang S, Nelson OD, Price IR, Zhu C, Lu X, Fernandez IR, Weiss RS, Lin H. Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2117013119. doi: 10.1073/pnas.2117013119. Epub 2022 Mar 8. PMID: 35259022; PMCID: PMC8931372.
Kobayashi M, Kobayashi M, Odajima J, Shioda K, Hwang YS, Sasaki K, Chatterjee P, Kramme C, Kohman RE, Church GM, Loehr AR, Weiss RS, Jüppner H, Gell JJ, Lau CC, Shioda T. Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers. Stem Cell Reports. 2022 Mar 8;17(3):507-521. doi: 10.1016/j.stemcr.2022.01.012. Epub 2022 Feb 10. PMID: 35148847; PMCID: PMC9039862.
Sims JR, Faça VM, Pereira C, Ascenção C, Comstock W, Badar J, Arroyo-Martinez GA, Freire R, Cohen PE, Weiss RS, Smolka MB. Phosphoproteomics of ATR signaling in mouse testes. Elife. 2022 Feb 8;11:e68648. doi: 10.7554/eLife.68648. PMID: 35133275; PMCID: PMC8824463.
Pereira C, Arroyo-Martinez GA, Guo MZ, Downey MS, Kelly ER, Grive KJ, Mahadevaiah SK, Sims JR, Faca VM, Tsai C, Schiltz CJ, Wit N, Jacobs H, Clark NL, Freire R, Turner J, Lyndaker AM, Brieno-Enriquez MA, Cohen PE, Smolka MB, Weiss RS. Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis. Elife. 2022 Feb 8;11:e68677. doi: 10.7554/eLife.68677. PMID: 35133274; PMCID: PMC8824475.

2021

Loehr AR, Pierpont TM, Gelsleichter E, Galang AMD, Fernandez IR, Moore ES, Guo MZ, Miller AD, Weiss RS. Targeting Cancer Stem Cells with Differentiation Agents as an Alternative to Genotoxic Chemotherapy for the Treatment of Malignant Testicular Germ Cell Tumors. Cancers (Basel). 2021 Apr 23;13(9):2045. doi: 10.3390/cancers13092045. PMID: 33922599; PMCID: PMC8122873.
Abril YLN, Fernandez IR, Hong JY, Chiang YL, Kutateladze DA, Zhao Q, Yang M, Hu J, Sadhukhan S, Li B, He B, Remick B, Bai JJ, Mullmann J, Wang F, Maymi V, Dhawan R, Auwerx J, Southard T, Cerione RA, Lin H, Weiss RS. Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer. Oncogene. 2021 Mar;40(9):1644-1658. doi: 10.1038/s41388-020-01637-w. Epub 2021 Jan 21. PMID: 33479498; PMCID: PMC7935767.
Lyndaker AM, Pierpont TM, Loehr AR, Weiss RS. A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors. Methods Mol Biol. 2021;2195:147-165. doi: 10.1007/978-1-0716-0860-9_11. PMID: 32852763.

Wolf

2025

Carrisoza-Gaytán R, Daily A, Wolf KJ, Lasaad S, Cantalupo A, Nair P, Van Gaal R, Uhlén P, Lewis JA, Satlin LM. Ca2+ signal dynamics in maturing ureteric bud (UB) and collecting duct (CD) derived organoid tubules. Am J Physiol Cell Physiol. 2025 Sep 30. doi: 10.1152/ajpcell.00578.2025. Epub ahead of print. PMID: 41026830.
Wolf KJ, van Gaal RC, Uzel SGM, Rubins JE, Klaus AN, Printz A, Nair P, Kroll KT, Stankey P, Satlin LM, Lewis JA. Perfusable 3D models of ureteric bud and collecting duct tubules. bioRxiv [Preprint]. 2025 Jun 24:2025.06.19.659798. doi: 10.1101/2025.06.19.659798. PMID: 40667187; PMCID: PMC12262377.

2024

Kroll KT, Homan KA, Uzel SGM, Mata MM, Wolf KJ, Rubins JE, Lewis JA. A perfusable, vascularized kidney organoid-on-chip model. Biofabrication. 2024 Jul 5;16(4). doi: 10.1088/1758-5090/ad5ac0. PMID: 38906132.

2023

Garcia JH, Akins EA, Jain S, Wolf KJ, Zhang J, Choudhary N, Lad M, Shukla P, Rios J, Seo K, Gill SA, Carson WH, Carette LR, Zheng AC, Raleigh DR, Kumar S, Aghi MK. Multiomic screening of invasive GBM cells reveals targetable transsulfuration pathway alterations. J Clin Invest. 2023 Nov 16;134(3):e170397. doi: 10.1172/JCI170397. PMID: 37971886; PMCID: PMC10849762.

2022

Wolf KJ, Weiss JD, Uzel SGM, Skylar-Scott MA, Lewis JA. Biomanufacturing human tissues via organ building blocks. Cell Stem Cell. 2022 May 5;29(5):667-677. doi: 10.1016/j.stem.2022.04.012. PMID: 35523137; PMCID: PMC9617289.

2021

Lei R, Akins EA, Wong KCY, Repina NA, Wolf KJ, Dempsey GE, Schaffer DV, Stahl A, Kumar S. Multiwell Combinatorial Hydrogel Array for High-Throughput Analysis of Cell-ECM Interactions. ACS Biomater Sci Eng. 2021 Jun 14;7(6):2453-2465. doi: 10.1021/acsbiomaterials.1c00065. Epub 2021 May 24. PMID: 34028263; PMCID: PMC8900525.

Wolfner

2025

Gordon KE, Ray S, Marcin JM, Gonzales PM, Li ML, Liang C, Wolfner MF, Lazzaro BP. Trade-off between antibacterial immune defense and oogenesis progression in female Drosophila melanogaster. Genetics. 2025 Oct 8;231(2):iyaf151. doi: 10.1093/genetics/iyaf151. PMID: 40746174; PMCID: PMC12505294.
Yang M, White MA, Findlay GD, Vignogna RC, Apger-McGlaughon J, Clark NL, Choi JY, Fromme JC, Wolfner MF. Female membrane proteins regulate postmating ovulation in Drosophila melanogaster by ovulin-dependent and -independent pathways. Proc Natl Acad Sci U S A. 2025 Sep 16;122(37):e2508783122. doi: 10.1073/pnas.2508783122. Epub 2025 Sep 8. PMID: 40920921; PMCID: PMC12452909.
Chen DS, Marrero K, Sanchez-Lopez JA, Belenky M, Thomalla JM, Buehner NA, Apel I, Levi Y, Hafezi Y, Wang S, Clark AG, Heifetz Y, Siegal ML, Wolfner MF. Asymmetric development and function of paired sperm-storage organs in Drosophila melanogaster. Proc Natl Acad Sci U S A. 2025 Aug 26;122(34):e2512096122. doi: 10.1073/pnas.2512096122. Epub 2025 Aug 19. PMID: 40828028; PMCID: PMC12403100.
Guay SY, Patel PH, Thomalla JM, McDermott KL, O’Toole JM, Arnold SE, Obrycki SJ, Wolfner MF, Findlay GD. An orphan gene is essential for efficient sperm entry into eggs in Drosophila melanogaster. Genetics. 2025 Mar 17;229(3):iyaf008. doi: 10.1093/genetics/iyaf008. PMID: 39903197; PMCID: PMC12168066.
Thomalla JM, Wolfner MF. No transcription, no problem: Protein phosphorylation changes and the transition from oocyte to embryo. Curr Top Dev Biol. 2025;162:165-205. doi: 10.1016/bs.ctdb.2025.01.001. Epub 2025 Feb 18. PMID: 40180509; PMCID: PMC12412753.

2024

Guay SY, Patel PH, Thomalla JM, McDermott KL, O’Toole JM, Arnold SE, Obrycki SJ, Wolfner MF, Findlay GD. An orphan gene is essential for efficient sperm entry into eggs in Drosophila melanogaster. bioRxiv [Preprint]. 2024 Dec 14:2024.08.08.607187. doi: 10.1101/2024.08.08.607187. Update in: Genetics. 2025 Mar 17;229(3):iyaf008. doi: 10.1093/genetics/iyaf008. PMID: 39149251; PMCID: PMC11326263.
Amaro IA, Wohl MP, Pitcher S, Alfonso-Parra C, Avila FW, Paige AS, Helinski MEH, Duvall LB, Harrington LC, Wolfner MF, McMeniman CJ. Sex peptide receptor is not required for refractoriness to remating or induction of egg laying in Aedes aegypti. Genetics. 2024 May 7;227(1):iyae034. doi: 10.1093/genetics/iyae034. PMID: 38551457; PMCID: PMC11075561.
Hafezi Y, Omurzakov A, Carlisle JA, Caldas IV, Wolfner MF, Clark AG. The Drosophila melanogaster Y-linked gene, WDY, is required for sperm to swim in the female reproductive tract. Commun Biol. 2024 Jan 12;7(1):90. doi: 10.1038/s42003-023-05717-x. PMID: 38216628; PMCID: PMC10786823.

2023

Brown NC, Gordon B, McDonough-Goldstein CE, Misra S, Findlay GD, Clark AG, Wolfner MF. The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster. Elife. 2023 Dec 21;12:e86409. doi: 10.7554/eLife.86409. PMID: 38126735; PMCID: PMC10834028.
Thomalla JM, Wolfner MF. Reproductive biology: A genetic recipe for parthenogenesis. Curr Biol. 2023 Sep 11;33(17):R904-R906. doi: 10.1016/j.cub.2023.07.055. PMID: 37699347; PMCID: PMC10753294.
Wolfner MF, Suarez SS, Dorus S. Suspension of hostility: Positive interactions between spermatozoa and female reproductive tracts. Andrology. 2023 Jul;11(5):943-947. doi: 10.1111/andr.13349. Epub 2022 Dec 22. PMID: 36448311; PMCID: PMC10227186.
Delbare SYN, Jain AM, Clark AG, Wolfner MF. Transcriptional programs are activated and microRNAs are repressed within minutes after mating in the Drosophila melanogaster female reproductive tract. BMC Genomics. 2023 Jun 27;24(1):356. doi: 10.1186/s12864-023-09397-z. PMID: 37370014; PMCID: PMC10294459.
Delbare SYN, Venkatraman S, Scuderi K, Wells MT, Wolfner MF, Basu S, Clark AG. Time series transcriptome analysis implicates the circadian clock in the Drosophila melanogaster female’s response to sex peptide. Proc Natl Acad Sci U S A. 2023 Jan 31;120(5):e2214883120. doi: 10.1073/pnas.2214883120. Epub 2023 Jan 27. Erratum in: Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2305270120. doi: 10.1073/pnas.2305270120. PMID: 36706221; PMCID: PMC9945991.

2022

Misra S, Buehner NA, Singh A, Wolfner MF. Female factors modulate Sex Peptide’s association with sperm in Drosophila melanogaster. BMC Biol. 2022 Dec 14;20(1):279. doi: 10.1186/s12915-022-01465-2. PMID: 36514080; PMCID: PMC9749180.
McQueen EW, Afkhami M, Atallah J, Belote JM, Gompel N, Heifetz Y, Kamimura Y, Kornhauser SC, Masly JP, O’Grady P, Peláez J, Rebeiz M, Rice G, Sánchez-Herrero E, Santos Nunes MD, Santos Rampasso A, Schnakenberg SL, Siegal ML, Takahashi A, Tanaka KM, Turetzek N, Zelinger E, Courtier-Orgogozo V, Toda MJ, Wolfner MF, Yassin A. A standardized nomenclature and atlas of the female terminalia of Drosophila melanogaster. Fly (Austin). 2022 Dec;16(1):128-151. doi: 10.1080/19336934.2022.2058309. PMID: 35575031; PMCID: PMC9116418.
Wigby S, Brown NC, Sepil I, Wolfner MF. On how to identify a seminal fluid protein: A commentary on Hurtado et al. Insect Mol Biol. 2022 Oct;31(5):533-536. doi: 10.1111/imb.12783. Epub 2022 Aug 17. PMID: 35975871; PMCID: PMC9452446.
Chen DS, Clark AG, Wolfner MF. Octopaminergic/tyraminergic Tdc2 neurons regulate biased sperm usage in female Drosophila melanogaster. Genetics. 2022 Jul 30;221(4):iyac096. doi: 10.1093/genetics/iyac096. PMID: 35809068; PMCID: PMC9339280.
White MA, Wolfner MF. The Effects of Male Seminal Fluid Proteins on Gut/Gonad Interactions in Drosophila. Insects. 2022 Jul 13;13(7):623. doi: 10.3390/insects13070623. PMID: 35886799; PMCID: PMC9324770.
Gordon KE, Wolfner MF, Lazzaro BP. A single mating is sufficient to induce persistent reduction of immune defense in mated female Drosophila melanogaster. J Insect Physiol. 2022 Jul;140:104414. doi: 10.1016/j.jinsphys.2022.104414. Epub 2022 Jun 18. PMID: 35728669; PMCID: PMC10162487.
McCullough EL, Whittington E, Singh A, Pitnick S, Wolfner MF, Dorus S. The life history of Drosophila sperm involves molecular continuity between male and female reproductive tracts. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2119899119. doi: 10.1073/pnas.2119899119. Epub 2022 Mar 7. PMID: 35254899; PMCID: PMC8931355.
Li H, Janssens J, De Waegeneer M, Kolluru SS, Davie K, Gardeux V, Saelens W, David FPA, Brbić M, Spanier K, Leskovec J, McLaughlin CN, Xie Q, Jones RC, Brueckner K, Shim J, Tattikota SG, Schnorrer F, Rust K, Nystul TG, Carvalho-Santos Z, Ribeiro C, Pal S, Mahadevaraju S, Przytycka TM, Allen AM, Goodwin SF, Berry CW, Fuller MT, White-Cooper H, Matunis EL, DiNardo S, Galenza A, O’Brien LE, Dow JAT; FCA Consortium§; Jasper H, Oliver B, Perrimon N, Deplancke B, Quake SR, Luo L, Aerts S, Agarwal D, Ahmed-Braimah Y, Arbeitman M, Ariss MM, Augsburger J, Ayush K, Baker CC, Banisch T, Birker K, Bodmer R, Bolival B, Brantley SE, Brill JA, Brown NC, Buehner NA, Cai XT, Cardoso-Figueiredo R, Casares F, Chang A, Clandinin TR, Crasta S, Desplan C, Detweiler AM, Dhakan DB, Donà E, Engert S, Floc’hlay S, George N, González-Segarra AJ, Groves AK, Gumbin S, Guo Y, Harris DE, Heifetz Y, Holtz SL, Horns F, Hudry B, Hung RJ, Jan YN, Jaszczak JS, Jefferis GSXE, Karkanias J, Karr TL, Katheder NS, Kezos J, Kim AA, Kim SK, Kockel L, Konstantinides N, Kornberg TB, Krause HM, Labott AT, Laturney M, Lehmann R, Leinwand S, Li J, Li JSS, Li K, Li K, Li L, Li T, Litovchenko M, Liu HH, Liu Y, Lu TC, Manning J, Mase A, Matera-Vatnick M, Matias NR, McDonough-Goldstein CE, McGeever A, McLachlan AD, Moreno-Roman P, Neff N, Neville M, Ngo S, Nielsen T, O’Brien CE, Osumi-Sutherland D, Özel MN, Papatheodorou I, Petkovic M, Pilgrim C, Pisco AO, Reisenman C, Sanders EN, Dos Santos G, Scott K, Sherlekar A, Shiu P, Sims D, Sit RV, Slaidina M, Smith HE, Sterne G, Su YH, Sutton D, Tamayo M, Tan M, Tastekin I, Treiber C, Vacek D, Vogler G, Waddell S, Wang W, Wilson RI, Wolfner MF, Wong YE, Xie A, Xu J, Yamamoto S, Yan J, Yao Z, Yoda K, Zhu R, Zinzen RP. Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science. 2022 Mar 4;375(6584):eabk2432. doi: 10.1126/science.abk2432. Epub 2022 Mar 4. PMID: 35239393; PMCID: PMC8944923.

2021

Amaro IA, Ahmed-Braimah YH, League GP, Pitcher SA, Avila FW, Cruz PC, Harrington LC, Wolfner MF. Seminal fluid proteins induce transcriptome changes in the Aedes aegypti female lower reproductive tract. BMC Genomics. 2021 Dec 15;22(1):896. doi: 10.1186/s12864-021-08201-0. PMID: 34906087; PMCID: PMC8672594.
League GP, Degner EC, Pitcher SA, Hafezi Y, Tennant E, Cruz PC, Krishnan RS, Garcia Castillo SS, Alfonso-Parra C, Avila FW, Wolfner MF, Harrington LC. The impact of mating and sugar feeding on blood-feeding physiology and behavior in the arbovirus vector mosquito Aedes aegypti. PLoS Negl Trop Dis. 2021 Sep 30;15(9):e0009815. doi: 10.1371/journal.pntd.0009815. PMID: 34591860; PMCID: PMC8509887.
White MA, Chen DS, Wolfner MF. She’s got nerve: roles of octopamine in insect female reproduction. J Neurogenet. 2021 Sep;35(3):132-153. doi: 10.1080/01677063.2020.1868457. Epub 2021 Apr 28. PMID: 33909537; PMCID: PMC8455407.
Suarez SS, Wolfner MF. Cilia take the egg on a magic carpet ride. Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2108887118. doi: 10.1073/pnas.2108887118. PMID: 34162738; PMCID: PMC8271566.
Meyer H, Buhr A, Callaerts P, Schiemann R, Wolfner MF, Marygold SJ. Identification and bioinformatic analysis of neprilysin and neprilysin-like metalloendopeptidases in Drosophila melanogaster. MicroPubl Biol. 2021 Jun 23;2021:10.17912/micropub.biology.000410. doi: 10.17912/micropub.biology.000410. PMID: 34189422; PMCID: PMC8223033.
Immarigeon C, Frei Y, Delbare SYN, Gligorov D, Machado Almeida P, Grey J, Fabbro L, Nagoshi E, Billeter JC, Wolfner MF, Karch F, Maeda RK. Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2001897118. doi: 10.1073/pnas.2001897118. PMID: 33876742; PMCID: PMC8053986.
Koreman GT, Xu Y, Hu Q, Zhang Z, Allen SE, Wolfner MF, Wang B, Han C. Upgraded CRISPR/Cas9 tools for tissue-specific mutagenesis in Drosophila. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2014255118. doi: 10.1073/pnas.2014255118. PMID: 33782117; PMCID: PMC8040800.
Ahmed-Braimah YH, Wolfner MF, Clark AG. Differences in Postmating Transcriptional Responses between Conspecific and Heterospecific Matings in Drosophila. Mol Biol Evol. 2021 Mar 9;38(3):986-999. doi: 10.1093/molbev/msaa264. PMID: 33035303; PMCID: PMC7947788.
Allen SE, Koreman GT, Sarkar A, Wang B, Wolfner MF, Han C. Versatile CRISPR/Cas9-mediated mosaic analysis by gRNA-induced crossing-over for unmodified genomes. PLoS Biol. 2021 Jan 14;19(1):e3001061. doi: 10.1371/journal.pbio.3001061. PMID: 33444322; PMCID: PMC7837743.
White MA, Bonfini A, Wolfner MF, Buchon N. Drosophila melanogaster sex peptide regulates mated female midgut morphology and physiology. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2018112118. doi: 10.1073/pnas.2018112118. PMID: 33443193; PMCID: PMC7817148.

Yu

2025

Zhang J, Leung AK, Zhu Y, Yao L, Willis A, Pan X, Ozer A, Zhou Z, Siklenka K, Barrera A, Liang J, Tippens ND, Reddy TE, Lis JT, Yu H. Comprehensive evaluation of diverse massively parallel reporter assays to functionally characterize human enhancers genome-wide. Genome Biol. 2025 Nov 3;26(1):378. doi: 10.1186/s13059-025-03828-8. PMID: 41185025; PMCID: PMC12581240.
Ozer A, Kang JJ, Tang Y, Yugandhar K, Yu S, DeBerardine MD, Omar K, Lis JT, Yu H. Identification of human RNA Polymerase II interactors at early stages of transcription. bioRxiv [Preprint]. 2025 Oct 8:2025.10.08.681243. doi: 10.1101/2025.10.08.681243. PMID: 41279442; PMCID: PMC12632396.
Shah SR, Chen Y, Leung AK, Navarro PVC, Paramo MI, Gupta J, Gurumurthy A, Fite RF, Weimer AK, Du Q, Mohyeldin AM, Egli D, Creusot RJ, Ryan RJH, Snyder MP, Clark AG, Lis JT, Yu H. The regulatory landscape of nascent transcription in human health and disease. bioRxiv [Preprint]. 2025 Sep 26:2025.09.24.676871. doi: 10.1101/2025.09.24.676871. PMID: 41040139; PMCID: PMC12485982.
Liu Y, Cooper DN, Yu H. Disease-specific variant pathogenicity prediction using multimodal biomedical language models. bioRxiv [Preprint]. 2025 Sep 15:2025.09.09.675184. doi: 10.1101/2025.09.09.675184. PMID: 41000707; PMCID: PMC12458274.
Xiong D, Qiu Y, Zhao J, Zhou Y, Lee D, Gupta S, Torres M, Lu W, Liang S, Kang JJ, Eng C, Loscalzo J, Cheng F, Yu H. A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations. Nat Biotechnol. 2025 Sep;43(9):1510-1524. doi: 10.1038/s41587-024-02428-4. Epub 2024 Oct 24. PMID: 39448882.
Odell J, Tang Y, Ambekar YS, Kidiyoor GR, Saadi H, Woodworth GF, Holt LJ, Scarcelli G, Yu H, Lammerding J. The Deformability of the Mammalian Cell Nucleus is Determined by the Identity of the Lamin Rod Domain. bioRxiv [Preprint]. 2025 Jul 22:2025.07.22.666133. doi: 10.1101/2025.07.22.666133. PMID: 40777269; PMCID: PMC12330664.
Zhou Z, Li A, Zhang J, Yu H, Ozer A, Lis JT. Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin context. bioRxiv [Preprint]. 2025 Jul 9:2025.07.07.663560. doi: 10.1101/2025.07.07.663560. PMID: 40672313; PMCID: PMC12265581.
Xiong D, Torres M, Murray D, Li L, Naravane AC, Fragoza R, Honig B, Yu H. Integrating structural homology with deep learning to achieve highly accurate protein-protein interface prediction for the human interactome. bioRxiv [Preprint]. 2025 Jun 12:2025.06.09.658393. doi: 10.1101/2025.06.09.658393. PMID: 40661495; PMCID: PMC12259034.
Yao L, Shah SR, Ozer A, Zhang J, Pan X, Xia T, Fangal VD, Leung AK, Wei M, Lis JT, Yu H. High-resolution reconstruction of cell-type specific transcriptional regulatory processes from bulk sequencing samples. bioRxiv [Preprint]. 2025 Apr 8:2025.04.02.646189. doi: 10.1101/2025.04.02.646189. PMID: 40291712; PMCID: PMC12026507.
Li L, Roy PG, Liu Y, Zhang Z, Xiong D, Savan R, Gokhale NS, Schang LM, Das J, Yu H. Comprehensive Atomic-Scale 3D Viral-Host Protein Interactomes Enable Dissection of Key Mechanisms and Evolutionary Processes Underlying Viral Pathogenesis. bioRxiv [Preprint]. 2025 Apr 2:2025.03.28.645946. doi: 10.1101/2025.03.28.645946. PMID: 40236211; PMCID: PMC11996397.
Paramo MI, Leung AK, Shah SR, Zhang J, Tippens ND, Liang J, Yao L, Jin Y, Pan X, Ozer A, Lis JT, Yu H. Simultaneous measurement of intrinsic promoter and enhancer potential reveals principles of functional duality and regulatory reciprocity. bioRxiv [Preprint]. 2025 Mar 14:2025.03.14.643265. doi: 10.1101/2025.03.14.643265. PMID: 40161809; PMCID: PMC11952525.
Zhang Y, Leung AK, Kang JJ, Sun Y, Wu G, Li L, Sun J, Cheng L, Qiu T, Zhang J, Wierbowski SD, Gupta S, Booth JG, Yu H. A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology. Nat Commun. 2025 Jan 24;16(1):975. doi: 10.1038/s41467-024-54176-3. PMID: 39856048; PMCID: PMC11760531.
Wang N, Pachai MR, Li D, Lee CJ, Warda S, Khudoynazarova MN, Cho WH, Xie G, Shah SR, Yao L, Qian C, Wong EWP, Yan J, Tomas FV, Hu W, Kuo F, Gao SP, Luo J, Smith AE, Han M, Gao D, Ge K, Yu H, Chandarlapaty S, Iyer GV, Rosenberg JE, Solit DB, Al-Ahmadie HA, Chi P, Chen Y. Loss of Kmt2c or Kmt2d primes urothelium for tumorigenesis and redistributes KMT2A-menin to bivalent promoters. Nat Genet. 2025 Jan;57(1):165-179. doi: 10.1038/s41588-024-02015-y. Epub 2025 Jan 13. PMID: 39806204; PMCID: PMC11735410.

2024

You Chen, Sagar R. Shah, Alden K. Leung, Mauricio I. Paramo, Kelly Cochran, Anshul Kundaje, Andrew G. Clark, John T. Lis, Haiyuan Yu. Directionality of transcriptional regulatory elements. bioRxiv. 2024 Dec 01; 621925; doi: https://doi.org/10.1101/2024.12.01.621925
Cochran K, Yin M, Mantripragada A, Schreiber J, Marinov GK, Shah SR, Yu H, Lis JT, Kundaje A. Dissecting the cis-regulatory syntax of transcription initiation with deep learning. bioRxiv [Preprint]. 2024 Nov 21:2024.05.28.596138. doi: 10.1101/2024.05.28.596138. PMID: 38853896; PMCID: PMC11160661.
Wan M, Minelli ME, Zhao Q, Marshall S, Yu H, Smolka M, Mao Y. Phosphoribosyl modification of poly-ubiquitin chains at the Legionella-containing vacuole prohibiting autophagy adaptor recognition. Nat Commun. 2024 Aug 30;15(1):7481. doi: 10.1038/s41467-024-51273-1. PMID: 39214972; PMCID: PMC11364841.
Zhou Y, Liu Y, Gupta S, Paramo MI, Hou Y, Mao C, Luo Y, Judd J, Wierbowski S, Bertolotti M, Nerkar M, Jehi L, Drayman N, Nicolaescu V, Gula H, Tay S, Randall G, Wang P, Lis JT, Feschotte C, Erzurum SC, Cheng F, Yu H. A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets. Nat Biotechnol. 2023 Jan;41(1):128-139. doi: 10.1038/s41587-022-01474-0. Epub 2022 Oct 10. PMID: 36217030; PMCID: PMC9851973.

2023

Chen Y, Paramo MI, Zhang Y, Yao L, Shah SR, Jin Y, Zhang J, Pan X, Yu H. Finding Needles in the Haystack: Strategies for Uncovering Noncoding Regulatory Variants. Annu Rev Genet. 2023 Nov 27;57:201-222. doi: 10.1146/annurev-genet-030723-120717. Epub 2023 Aug 10. PMID: 37562413.
Ding X, Singh P, Schimenti K, Tran TN, Fragoza R, Hardy J, Orwig KE, Olszewska M, Kurpisz MK, Yatsenko AN, Conrad DF, Yu H, Schimenti JC. In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2219925120. doi: 10.1073/pnas.2219925120. Epub 2023 Jul 17. PMID: 37459509; PMCID: PMC10372637.

2022

Leung AK, Yao L, Yu H. Functional genomic assays to annotate enhancer-promoter interactions genome wide. Hum Mol Genet. 2022 Oct 20;31(R1):R97-R104. doi: 10.1093/hmg/ddac204. PMID: 36018818; PMCID: PMC9585677.
Santos MN, Paushter DH, Zhang T, Wu X, Feng T, Lou J, Du H, Becker SM, Fragoza R, Yu H, Hu F. Progranulin-derived granulin E and lysosome membrane protein CD68 interact to reciprocally regulate their protein homeostasis. J Biol Chem. 2022 Sep;298(9):102348. doi: 10.1016/j.jbc.2022.102348. Epub 2022 Aug 4. PMID: 35933009; PMCID: PMC9450144.
Yao L, Liang J, Ozer A, Leung AK, Lis JT, Yu H. A comparison of experimental assays and analytical methods for genome-wide identification of active enhancers. Nat Biotechnol. 2022 Jul;40(7):1056-1065. doi: 10.1038/s41587-022-01211-7. Epub 2022 Feb 17. PMID: 35177836; PMCID: PMC9288987.
Lee D, Xiong D, Wierbowski S, Li L, Liang S, Yu H. Deep learning methods for 3D structural proteome and interactome modeling. Curr Opin Struct Biol. 2022 Apr;73:102329. doi: 10.1016/j.sbi.2022.102329. Epub 2022 Feb 6. PMID: 35139457; PMCID: PMC8957610.
Chen Y, Clark AG, Yu H. Advancing discovery of risk-altering variants for complex diseases by functionally informed fine-mapping. Neuron. 2022 Mar 16;110(6):905-907. doi: 10.1016/j.neuron.2022.02.018. PMID: 35298913.
Hou Y, Zhou Y, Jehi L, Luo Y, Gack MU, Chan TA, Yu H, Eng C, Pieper AA, Cheng F. Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients. Aging Cell. 2022 Feb;21(2):e13544. doi: 10.1111/acel.13544. Epub 2022 Jan 12. PMID: 35023286; PMCID: PMC8844132.
Xiong D, Lee D, Li L, Zhao Q, Yu H. Implications of disease-related mutations at protein-protein interfaces. Curr Opin Struct Biol. 2022 Feb;72:219-225. doi: 10.1016/j.sbi.2021.11.012. Epub 2021 Dec 24. PMID: 34959033; PMCID: PMC8863207.
Chen S, Liu Y, Zhang Y, Wierbowski SD, Lipkin SM, Wei X, Yu H. A full-proteome, interaction-specific characterization of mutational hotspots across human cancers. Genome Res. 2022 Jan;32(1):135-149. doi: 10.1101/gr.275437.121. Epub 2021 Dec 28. PMID: 34963661; PMCID: PMC8744679.

2021

Wierbowski SD, Liang S, Liu Y, Chen Y, Gupta S, Andre NM, Lipkin SM, Whittaker GR, Yu H. A 3D structural SARS-CoV-2-human interactome to explore genetic and drug perturbations. Nat Methods. 2021 Dec;18(12):1477-1488. doi: 10.1038/s41592-021-01318-w. Epub 2021 Nov 29. PMID: 34845387; PMCID: PMC8665054.
Yugandhar K, Zhao Q, Gupta S, Xiong D, Yu H. Progress in methodologies and quality-control strategies in protein cross-linking mass spectrometry. Proteomics. 2021 Dec;21(23-24):e2100145. doi: 10.1002/pmic.202100145. Epub 2021 Oct 28. PMID: 34647422.
Furman CM, Wang TY, Zhao Q, Yugandhar K, Yu H, Alani E. Handcuffing intrinsically disordered regions in Mlh1-Pms1 disrupts mismatch repair. Nucleic Acids Res. 2021 Sep 20;49(16):9327-9341. doi: 10.1093/nar/gkab694. PMID: 34390347; PMCID: PMC8450099.
Singh P, Fragoza R, Blengini CS, Tran TN, Pannafino G, Al-Sweel N, Schimenti KJ, Schindler K, Alani EA, Yu H, Schimenti JC. Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging. Nat Commun. 2021 Aug 18;12(1):5005. doi: 10.1038/s41467-021-25028-1. PMID: 34408140; PMCID: PMC8373927.
Joiner AM, Phillips BP, Yugandhar K, Sanford EJ, Smolka MB, Yu H, Miller EA, Fromme JC. Structural basis of TRAPPIII-mediated Rab1 activation. EMBO J. 2021 Jun 15;40(12):e107607. doi: 10.15252/embj.2020107607. Epub 2021 May 21. PMID: 34018207; PMCID: PMC8204860.
Zhou Y, Xu J, Hou Y, Leverenz JB, Kallianpur A, Mehra R, Liu Y, Yu H, Pieper AA, Jehi L, Cheng F. Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment. Alzheimers Res Ther. 2021 Jun 9;13(1):110. doi: 10.1186/s13195-021-00850-3. PMID: 34108016; PMCID: PMC8189279.
Du H, Wong MY, Zhang T, Santos MN, Hsu C, Zhang J, Yu H, Luo W, Hu F. A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses. Life Sci Alliance. 2021 Jun 8;4(7):e202000874. doi: 10.26508/lsa.202000874. PMID: 34103390; PMCID: PMC8200295.
Li G, Pahari S, Murthy AK, Liang S, Fragoza R, Yu H, Alexov E. SAAMBE-SEQ: a sequence-based method for predicting mutation effect on protein-protein binding affinity. Bioinformatics. 2021 May 17;37(7):992-999. doi: 10.1093/bioinformatics/btaa761. PMID: 32866236; PMCID: PMC8128451.
Lanz MC, Yugandhar K, Gupta S, Sanford EJ, Faça VM, Vega S, Joiner AMN, Fromme JC, Yu H, Smolka MB. In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep. 2021 Feb 3;22(2):e51121. doi: 10.15252/embr.202051121. Epub 2021 Jan 25. PMID: 33491328; PMCID: PMC7857435.
Zhang, Y., Wierbowski, S.D. & Yu, H. Combining views for newly sequenced organisms. Nat Mach Intell 3, 1011–1012 (2021). https://doi.org/10.1038/s42256-021-00426-8

Zeng

2025

Choi I, Kim KA, Kim SC, Park D, Nam KT, Cha JH, Baek S, Cha J, Jo HY, Jung M, Zeng MY, Matei I, Bullman S, Ahn JB, Han YD, Kim HS, Lee I. Secretory IgA dysfunction underlies poor prognosis in Fusobacterium-infected colorectal cancer. Gut Microbes. 2025 Dec;17(1):2528428. doi: 10.1080/19490976.2025.2528428. Epub 2025 Jul 16. PMID: 40667611; PMCID: PMC12269704.
Iliev ID, Blander JM, Collins N, Guo CJ, Longman RS, Sonnenberg GF, Zeng MY, Artis D. Microbiota-mediated mechanisms of mucosal immunity across the lifespan. Nat Immunol. 2025 Oct;26(10):1645-1659. doi: 10.1038/s41590-025-02281-w. Epub 2025 Sep 16. PMID: 40957908; PMCID: PMC12700289.
Wang Z, Lipshutz A, Martínez de la Torre C, Trzeciak AJ, Liu ZL, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A, Schild T, Saitz Rojas W, Saavedra PHV, Baako AK, Fadojutimi K, Downey MS, Geissmann F, Faraco G, Gan L, Etchegaray JI, Lucas CD, Tanasova M, Parkhurst CN, Zeng MY, Keshari KR, Perry JSA. Early life high fructose impairs microglial phagocytosis and neurodevelopment. Nature. 2025 Aug;644(8077):759-768. doi: 10.1038/s41586-025-09098-5. Epub 2025 Jun 11. PMID: 40500435; PMCID: PMC7617807.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY, Hu Y, Mortensen RM, Greenson JK, Cascalho M, Wobus CE, Colacino JA, Nunez G, Rui L, Shah YM. Author Correction: Intestinal non-canonical NFκB signaling shapes the local and systemic immune response. Nat Commun. 2025 Jul 8;16(1):6280. doi: 10.1038/s41467-025-61581-9. Erratum for: Nat Commun. 2019 Feb 8;10(1):660. doi: 10.1038/s41467-019-08581-8. PMID: 40628801; PMCID: PMC12238639.
Brown JA, Bashir H, Zeng MY. Lifelong partners: Gut microbiota-immune cell interactions from infancy to old age. Mucosal Immunol. 2025 Jun;18(3):509-523. doi: 10.1016/j.mucimm.2025.01.006. Epub 2025 Jan 23. PMID: 39862964; PMCID: PMC12167161.
Wang W, Wang Y, Sanidad KZ, Wang Y, Zhang J, Yang W, Sun Q, Bayram I, Song R, Yang H, Johnson D, Sherman HL, Kim D, Minter LM, Wong JJ, Zeng MY, Decker EA, Zhang G. Oxidized Polyunsaturated Fatty Acid Promotes Colitis and Colitis-Associated Tumorigenesis in Mice. J Crohns Colitis. 2025 Mar 5;19(3):jjae148. doi: 10.1093/ecco-jcc/jjae148. PMID: 39279209; PMCID: PMC13032040.
Behnsen J, Huang KC, Sorbara MT, Wang MC, Yu J, Zeng MY. New opportunities in mechanistic and functional microbiome studies. Cell Chem Biol. 2025 Jan 16;32(1):5-8. doi: 10.1016/j.chembiol.2024.12.012. PMID: 39824158.

2024

Ardeshir A, Gensollen T, Zeng M, Al Nabhani Z, Blumberg R. Editorial: The early life window of opportunity: role of the microbiome on immune system imprinting. Front Immunol. 2024 May 3;15:1417060. doi: 10.3389/fimmu.2024.1417060. PMID: 38765014; PMCID: PMC11099258.
Sanidad KZ, Rager SL, Carrow HC, Ananthanarayanan A, Callaghan R, Hart LR, Li T, Ravisankar P, Brown JA, Amir M, Jin JC, Savage AR, Luo R, Rowdo FM, Martin ML, Silver RB, Guo CJ, Krumsiek J, Inohara N, Zeng MY. Gut bacteria-derived serotonin promotes immune tolerance in early life. Sci Immunol. 2024 Mar 15;9(93):eadj4775. doi: 10.1126/sciimmunol.adj4775. Epub 2024 Mar 15. PMID: 38489352; PMCID: PMC11328322.

2023

Yu S, Zeng MY. Sex-biased gut dopamine signaling in multiple sclerosis. Immunity. 2023 Dec 12;56(12):2674-2676. doi: 10.1016/j.immuni.2023.11.016. PMID: 38091947; PMCID: PMC10908588.
Yao Y, Choe U, Li Y, Liu Z, Zeng M, Wang TTY, Sun J, Wu X, Pehrsson P, He X, Zhang Y, Gao B, Moore JC, Chen P, Slavin M, Yu LL. Chemical Composition of Rosemary (Rosmarinus officinalis L.) Extract and Its Inhibitory Effects on SARS-CoV-2 Spike Protein-ACE2 Interaction and ACE2 Activity and Free Radical Scavenging Capacities. J Agric Food Chem. 2023 Dec 6;71(48):18735-18745. doi: 10.1021/acs.jafc.3c02301. Epub 2023 Nov 21. PMID: 37988686.
Wang Z, Lipshutz A, Liu ZL, Trzeciak AJ, Miranda IC, Martínez de la Torre C, Schild T, Lazarov T, Rojas WS, Saavedra PHV, Romero-Pichardo JE, Baako A, Geissmann F, Faraco G, Gan L, Etchegaray JI, Lucas CD, Parkhurst CN, Zeng MY, Keshari KR, Perry JSA. Early life high fructose exposure disrupts microglia function and impedes neurodevelopment. bioRxiv [Preprint]. 2023 Aug 15:2023.08.14.553242. doi: 10.1101/2023.08.14.553242. PMID: 37645894; PMCID: PMC10462086.
Jin JC, Ananthanarayanan A, Brown JA, Rager SL, Bram Y, Sanidad KZ, Amir M, Baergen RN, Stuhlmann H, Schwartz RE, Perlman JM, Zeng MY. SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy. Pediatr Res. 2023 Apr;93(5):1375-1382. doi: 10.1038/s41390-022-02266-7. Epub 2022 Aug 19. PMID: 35986143; PMCID: PMC9388973.
Xie Z, Li Y, Liu Z, Zeng M, Moore JC, Gao B, Wu X, Sun J, Wang TTY, Pehrsson P, He X, Yu LL. Bioactive Compositions of Cinnamon (Cinnamomum verum J. Presl) Extracts and Their Capacities in Suppressing SARS-CoV-2 Spike Protein Binding to ACE2, Inhibiting ACE2, and Scavenging Free Radicals. J Agric Food Chem. 2023 Mar 29;71(12):4890-4900. doi: 10.1021/acs.jafc.3c00285. Epub 2023 Mar 20. PMID: 36940448.
Rager SL, Zeng MY. The Gut-Liver Axis in Pediatric Liver Health and Disease. Microorganisms. 2023 Feb 27;11(3):597. doi: 10.3390/microorganisms11030597. PMID: 36985171; PMCID: PMC10051507.

2022

Li Y, Liu Z, Zeng M, El Kadiri A, Huang J, Kim A, He X, Sun J, Chen P, Wang TTY, Zhang Y, Gao B, Xie Z, Yu LL. Chemical Compositions of Clove (Syzygium aromaticum (L.) Merr. & L.) Extracts and Their Potentials in Suppressing SARS-CoV-2 Spike Protein-ACE2 Binding, Inhibiting ACE2, and Scavenging Free Radicals. J Agric Food Chem. 2022 Nov 16;70(45):14403-14413. doi: 10.1021/acs.jafc.2c06300. Epub 2022 Nov 1. PMID: 36318658.
Sanidad KZ, Amir M, Ananthanarayanan A, Singaraju A, Shiland NB, Hong HS, Kamada N, Inohara N, Núñez G, Zeng MY. Maternal gut microbiome-induced IgG regulates neonatal gut microbiome and immunity. Sci Immunol. 2022 Jun 10;7(72):eabh3816. doi: 10.1126/sciimmunol.abh3816. Epub 2022 Jun 10. PMID: 35687695; PMCID: PMC9375732.
Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, Schmidt F, Weisblum Y, Cioffi M, Li T, Rowdo FM, Martin ML, Guo CJ, Lyssiotis C, Layden BT, Dannenberg AJ, Bieniasz PD, Lee B, Inohara N, Matei I, Plemper RK, Zeng MY. Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection. Gut Microbes. 2022 Jan-Dec;14(1):2105609. doi: 10.1080/19490976.2022.2105609. PMID: 35915556; PMCID: PMC9348133.

2021

Amir M, Zeng MY. Immune imprinting in utero. Science. 2021 Aug 27;373(6558):967-968. doi: 10.1126/science.abl3631. PMID: 34446596; PMCID: PMC8740897.

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